Motif ID: PAX4.p2

Z-value: 1.568


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX4chr7_-_127042810-0.224.1e-01Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_101475149 4.182 S1PR1
sphingosine-1-phosphate receptor 1
chr4_+_39874921 4.015 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_12046020 3.285 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_+_101474892 3.177 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr8_-_21827057 2.738 NM_003974
DOK2
docking protein 2, 56kDa
chr1_-_158948176 2.401 NM_001778
CD48
CD48 molecule
chr6_+_32515596 2.239 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_+_1830763 2.150 NM_002339
LSP1
lymphocyte-specific protein 1
chr6_+_32713160 2.142 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_2928480 2.063 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr3_+_120781212 1.941 NM_001125
ADPRH
ADP-ribosylarginine hydrolase
chr7_+_26158257 1.930 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr1_-_25164061 1.900 NM_001031680
RUNX3
runt-related transcription factor 3
chr8_+_145718702 1.826


chr4_-_113426332 1.708 NM_052864
TIFA
TRAF-interacting protein with forkhead-associated domain
chr4_-_84250019 1.487 NM_001130716
PLAC8
placenta-specific 8
chr12_+_115481568 1.452 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr18_-_59137488 1.386 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr10_-_85921703 1.372 LOC642934
hypothetical LOC642934
chr2_-_136590210 1.334 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr11_-_58736897 1.333 NM_001039396
MPEG1
macrophage expressed 1
chr19_-_50688310 1.330 NM_206901
RTN2
reticulon 2
chr12_+_103375116 1.277 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr3_+_123779122 1.268 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr1_-_208024491 1.239 NM_152485
C1orf74
chromosome 1 open reading frame 74
chr20_-_23010786 1.217 CD93
CD93 molecule
chr1_+_149299530 1.211 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_96351345 1.199


chr1_+_149299504 1.176 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr17_+_22823151 1.168 NM_014238
KSR1
kinase suppressor of ras 1
chr18_-_51406841 1.160 NM_001083962
NM_003199
TCF4

transcription factor 4

chr5_+_162862808 1.158 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr17_+_4795128 1.145 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr7_+_26298136 1.131 SNX10
sorting nexin 10
chr19_+_14405216 1.113 PKN1
protein kinase N1
chr1_+_149299490 1.100 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr19_-_59476734 1.060 NM_001080978
NM_005874
LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2

chr6_-_137536412 1.057 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr11_+_20341806 1.039 NM_006410
NM_001098521
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr6_-_32665409 1.034 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr3_-_17757402 1.020 NM_014744
TBC1D5
TBC1 domain family, member 5
chr6_+_31661934 0.989 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr12_+_32003553 0.988 NM_018169
C12orf35
chromosome 12 open reading frame 35
chrX_-_101297417 0.987 NM_001159560
NM_001012978
BEX5

brain expressed, X-linked 5

chr12_+_32003648 0.975 C12orf35
chromosome 12 open reading frame 35
chr11_+_20341900 0.971 NM_001098522
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr1_+_15675182 0.968 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr1_-_202730135 0.967 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chrX_+_65300803 0.941 NM_001130860
NM_014799
HEPH

hephaestin

chr4_-_109308893 0.926 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr4_+_140806371 0.922 NM_002413
MGST2
microsomal glutathione S-transferase 2
chr18_+_71051713 0.919 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr4_+_140806536 0.912 MGST2
microsomal glutathione S-transferase 2
chr5_+_42792676 0.911 NM_001134848
CCDC152
coiled-coil domain containing 152
chr13_-_40491491 0.901 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_-_176970407 0.895 GPM6A
glycoprotein M6A
chr1_+_149298774 0.873 NM_006818
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_68703036 0.871 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr6_+_31662454 0.871 NM_205837
LST1
leukocyte specific transcript 1
chr7_-_23476497 0.867 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr19_-_46504831 0.866


chr12_-_93568336 0.862 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr22_-_16080265 0.854 CECR1
cat eye syndrome chromosome region, candidate 1
chrX_-_47815426 0.843 NM_001037735
ZNF630
zinc finger protein 630
chr3_+_188222337 0.839 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr1_-_158759606 0.834 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr1_-_149298706 0.828 NM_001038707
NM_020239
CDC42SE1

CDC42 small effector 1

chr1_+_149299307 0.821 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr22_-_20314366 0.812 YDJC
YdjC homolog (bacterial)
chr13_-_28190961 0.801 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr7_-_135263737 0.793 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr1_-_30977931 0.784 LAPTM5
lysosomal protein transmembrane 5
chr7_+_68702516 0.777 AUTS2
autism susceptibility candidate 2
chrX_+_154880439 0.770 NM_002186
IL9R
interleukin 9 receptor
chr20_-_30703219 0.749 NM_182584
C20orf203
chromosome 20 open reading frame 203
chr19_+_17239264 0.735 BABAM1
BRISC and BRCA1 A complex member 1
chr11_-_67174684 0.735 NM_080658
ACY3
aspartoacylase (aminocyclase) 3
chr17_-_44037332 0.730 NM_018952
HOXB6
homeobox B6
chr3_-_79899748 0.728 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr15_+_64481270 0.725 MAP2K1
mitogen-activated protein kinase kinase 1
chr11_+_20341835 0.723 NM_001098520
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr6_-_90119329 0.720 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr7_+_68702252 0.710 AUTS2
autism susceptibility candidate 2
chr4_-_176970372 0.710 GPM6A
glycoprotein M6A
chr6_-_50025115 0.708 NM_001166478
DEFB133
defensin, beta 133
chr17_+_69781980 0.683 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr2_-_232087293 0.677 C2orf52
chromosome 2 open reading frame 52
chr9_+_27099138 0.669 NM_000459
TEK
TEK tyrosine kinase, endothelial
chrX_+_106050261 0.668 NM_020384
CLDN2
claudin 2
chr5_+_68702617 0.655 NM_133340
NM_133341
RAD17

RAD17 homolog (S. pombe)

chr7_+_150013716 0.650 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr19_-_55008172 0.643 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr7_-_112545840 0.642 LOC401397
hypothetical LOC401397
chr6_+_31690957 0.636 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr19_+_59833719 0.635 NM_001081638
NM_001081639
NM_001081637
LILRB1


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1


chr16_+_28850760 0.632 NM_001178098
NM_001770
CD19

CD19 molecule

chr7_+_77307382 0.632 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr6_-_90119169 0.631 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr6_-_32913797 0.626 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_38170004 0.626 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr7_-_112545847 0.625 LOC401397
hypothetical LOC401397
chr1_+_84540921 0.625 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr17_-_39651189 0.621 NM_014233
UBTF
upstream binding transcription factor, RNA polymerase I
chr19_-_55834895 0.620 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr15_+_78232232 0.613 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr8_-_102029997 0.610 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr20_+_61654816 0.610 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr12_+_54832470 0.603 NM_002475
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr1_-_158815850 0.603 CD84
CD84 molecule
chr15_+_78232160 0.601 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr10_+_35524835 0.600 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr5_-_43550891 0.591 NM_198566
C5orf34
chromosome 5 open reading frame 34
chr16_-_87297525 0.591 NM_001171816
RNF166
ring finger protein 166
chr20_-_4743768 0.589 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr3_+_195887903 0.589 NM_153690
FAM43A
family with sequence similarity 43, member A
chr19_+_14405100 0.578 NM_002741
PKN1
protein kinase N1
chr12_-_6615348 0.572 NM_020400
LPAR5
lysophosphatidic acid receptor 5
chr3_+_190831909 0.568 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr18_-_59137948 0.568 BCL2
B-cell CLL/lymphoma 2
chr2_-_64944214 0.561


chr7_+_106292975 0.557 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_+_82171142 0.556 NM_001201
BMP3
bone morphogenetic protein 3
chr7_-_33047042 0.555 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr11_+_65027721 0.553


chr4_-_40212670 0.552 NM_019027
RBM47
RNA binding motif protein 47
chr1_-_229443479 0.552 NM_152379
C1orf131
chromosome 1 open reading frame 131
chr15_+_78232184 0.547 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr9_+_109131814 0.547 RAD23B
RAD23 homolog B (S. cerevisiae)
chr4_-_176970895 0.540 GPM6A
glycoprotein M6A
chr12_+_69148120 0.539


chr7_-_149960218 0.539 GIMAP6
GTPase, IMAP family member 6
chr12_+_74160779 0.538 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr10_+_6226764 0.536 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chrX_-_154216929 0.533 NM_001289
CLIC2
chloride intracellular channel 2
chr19_+_10077898 0.533 NM_020230
NM_001040664
NM_001198690
PPAN
PPAN-P2RY11

peter pan homolog (Drosophila)
PPAN-P2RY11 readthrough

chr19_+_17239148 0.533 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1

chr1_+_208067986 0.529 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr20_+_42644633 0.527 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr18_-_59138192 0.525 BCL2
B-cell CLL/lymphoma 2
chr14_+_66901237 0.523 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr15_-_58477407 0.519 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr12_-_55432348 0.517 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr1_-_39910296 0.515 NM_032526
NT5C1A
5'-nucleotidase, cytosolic IA
chr10_-_32707549 0.511 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr9_-_129707392 0.510 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_47468029 0.506 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr15_+_78232395 0.499 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr21_+_42807052 0.496 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr6_+_42859133 0.495 FLJ38717
FLJ38717 protein
chr12_+_25096755 0.493 LRMP
lymphoid-restricted membrane protein
chr7_+_134567270 0.491 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr1_+_229443582 0.489 GNPAT
glyceronephosphate O-acyltransferase
chr15_+_78232194 0.489 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr19_-_4867814 0.485


chr1_-_26517342 0.485 NM_145345
UBXN11
UBX domain protein 11
chr1_-_31003181 0.482 LAPTM5
lysosomal protein transmembrane 5
chr12_+_122283411 0.482 C12orf65
chromosome 12 open reading frame 65
chr12_-_119172339 0.480 NM_025157
PXN
paxillin
chr4_+_22608252 0.477


chr15_-_20638283 0.473 NM_001142275
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr19_-_60320592 0.471 NM_017607
PPP1R12C
protein phosphatase 1, regulatory (inhibitor) subunit 12C
chr1_+_229443575 0.469 GNPAT
glyceronephosphate O-acyltransferase
chr4_+_47181987 0.468 NM_020453
ATP10D
ATPase, class V, type 10D
chr2_+_215884923 0.468 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_+_133884388 0.468 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr18_+_28023984 0.467 NM_005925
MEP1B
meprin A, beta
chr13_-_24395054 0.466 NM_018451
CENPJ
centromere protein J
chr4_+_75242671 0.466 NM_001144978
MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr1_+_208067974 0.463 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr9_-_98580148 0.462 NM_014930
ZNF510
zinc finger protein 510
chr2_+_218833982 0.459 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr2_+_215885053 0.458 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_+_33151703 0.458 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr17_+_40655060 0.454 NM_005892
FMNL1
formin-like 1
chrX_-_46889009 0.454 NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr16_+_31273969 0.452 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_-_231498184 0.452 NM_005683
GPR55
G protein-coupled receptor 55
chr12_-_112058403 0.452 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chrX_-_52562712 0.450 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr2_-_213723298 0.449 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_-_107234702 0.447 SLC35F2
solute carrier family 35, member F2
chr1_+_148726537 0.445 NM_025150
TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr1_+_26516967 0.445 NM_001803
CD52
CD52 molecule
chr2_+_102345528 0.441 NM_003855
IL18R1
interleukin 18 receptor 1
chr4_+_123311207 0.436 NM_015312
KIAA1109
KIAA1109
chr1_+_208067890 0.436 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr11_+_113671744 0.434 NM_006169
NNMT
nicotinamide N-methyltransferase
chr7_-_126680372 0.428 GRM8
glutamate receptor, metabotropic 8
chr6_-_31805932 0.428 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_16111594 0.427


chr1_+_51208499 0.426 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr1_+_148726497 0.425 TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr6_-_31806012 0.424 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr12_-_116890410 0.422 NM_173598
KSR2
kinase suppressor of ras 2
chrX_-_52276878 0.421 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr14_+_20319049 0.420 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr10_-_61570665 0.418 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_69216747 0.417 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_-_84099261 0.411


chrX_-_134257624 0.408 NM_001185063
NM_007131
ZNF75D

zinc finger protein 75D


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.