Motif ID: PATZ1.p2

Z-value: 2.568


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300715650.665.1e-03Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_34114924 8.113 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_-_25328452 5.884 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_+_34115383 4.248 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chrX_+_9392980 4.079 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr16_+_88542639 3.789 NM_017702
NM_207514
DEF8

differentially expressed in FDCP 8 homolog (mouse)

chr1_-_32574185 3.674 NM_023009
MARCKSL1
MARCKS-like 1
chr19_-_55524445 3.566 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr20_-_62181588 3.467 NM_001039467
RGS19
regulator of G-protein signaling 19
chr17_-_73636386 3.354 NM_001127198
TMC6
transmembrane channel-like 6
chr20_-_30534848 3.315 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr17_-_34015631 3.307 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr17_-_73636362 3.294 TMC6
transmembrane channel-like 6
chr8_+_144706699 3.263 NM_001166237
GSDMD
gasdermin D
chr6_+_34312979 3.259 HMGA1
high mobility group AT-hook 1
chr6_+_34313007 3.237 HMGA1
high mobility group AT-hook 1
chr16_+_1979959 3.184 NM_004209
SYNGR3
synaptogyrin 3
chr1_+_3679168 3.174 NM_001163724
LOC388588
hypothetical protein LOC388588
chr9_+_70509925 3.109 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr9_-_125732005 3.059 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chrX_+_138060 2.999 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr2_-_174537354 2.969 SP3
Sp3 transcription factor
chr22_-_17545872 2.891 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_-_77094426 2.857 ACTG1
actin, gamma 1
chr19_-_2653662 2.827 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr17_-_77094375 2.822 NM_001614
ACTG1
actin, gamma 1
chr17_-_71352090 2.810 UNC13D
unc-13 homolog D (C. elegans)
chr22_-_17546296 2.786 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr9_-_115178969 2.779 HDHD3
haloacid dehalogenase-like hydrolase domain containing 3
chr20_+_61841662 2.753 SLC2A4RG
SLC2A4 regulator
chr16_-_88613287 2.749 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr19_+_34994701 2.699 NM_001238
CCNE1
cyclin E1
chr10_+_124885556 2.663 NM_001105574
HMX3
H6 family homeobox 3
chr20_+_61841553 2.648 NM_020062
SLC2A4RG
SLC2A4 regulator
chr1_-_21868380 2.647 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr22_-_17546234 2.630 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr20_+_30813851 2.595 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr17_-_71352017 2.547 UNC13D
unc-13 homolog D (C. elegans)
chr16_+_87047159 2.542 ZFPM1
zinc finger protein, multitype 1
chr19_-_2653738 2.534 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr20_-_62181231 2.532 NM_005873
RGS19
regulator of G-protein signaling 19
chr17_+_52688842 2.491 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr2_+_170298700 2.488 KLHL23
kelch-like 23 (Drosophila)
chr19_+_8180179 2.443 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr7_-_158073121 2.435 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr9_+_94860769 2.413 NM_145006
SUSD3
sushi domain containing 3
chr11_+_63829616 2.406 NM_004451
ESRRA
estrogen-related receptor alpha
chr9_+_94860828 2.401 SUSD3
sushi domain containing 3
chr3_-_13436725 2.395 NUP210
nucleoporin 210kDa
chr19_-_4017739 2.389 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr6_+_37245860 2.384 NM_002648
PIM1
pim-1 oncogene
chr7_-_100077072 2.375 NM_003227
TFR2
transferrin receptor 2
chr6_+_34313347 2.374 HMGA1
high mobility group AT-hook 1
chr19_+_659766 2.354 NM_001040134
NM_002579
PALM

paralemmin

chr17_+_44429748 2.327 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr22_-_17546276 2.310 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_-_18807805 2.307 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr22_+_20101661 2.303 NM_015094
HIC2
hypermethylated in cancer 2
chr20_+_30814048 2.274 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr3_-_13436802 2.254 NM_024923
NUP210
nucleoporin 210kDa
chr2_+_218972963 2.247 NM_182642
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr22_+_38183480 2.193 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr20_+_34635362 2.165 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr16_+_29725311 2.152 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr11_+_63758550 2.139 NM_003377
VEGFB
vascular endothelial growth factor B
chr16_+_29730909 2.131 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr17_-_71352182 2.109 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr4_+_1764802 2.109 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr1_+_945331 2.109 NM_198576
AGRN
agrin
chr7_-_103417198 2.109 NM_005045
NM_173054
RELN

reelin

chr13_-_113066366 2.099 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr11_+_46358909 2.098 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr6_+_11646472 2.086 NM_001100829
TMEM170B
transmembrane protein 170B
chr22_-_21231421 2.081 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr17_-_39632845 2.080 ATXN7L3
ataxin 7-like 3
chr19_-_14062230 2.065 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr6_-_32265489 2.058 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr17_+_73676219 2.055 NM_004710
SYNGR2
synaptogyrin 2
chr2_-_61551403 2.049 USP34
ubiquitin specific peptidase 34
chr5_+_139008667 2.038 CXXC5
CXXC finger protein 5
chr5_+_176446425 2.037 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr7_-_150305933 2.015 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr9_-_122679387 1.990 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr12_-_61614930 1.988 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_34312906 1.941 HMGA1
high mobility group AT-hook 1
chr14_-_90953883 1.928 NM_001080414
CCDC88C
coiled-coil domain containing 88C
chr16_+_29731058 1.927 PRRT2
proline-rich transmembrane protein 2
chr7_-_150306169 1.923 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr21_-_37260488 1.920 HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr16_+_2461500 1.916 NM_006181
NTN3
netrin 3
chr13_-_113066202 1.913 GRTP1
growth hormone regulated TBC protein 1
chr12_+_56202874 1.899 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr22_-_49042065 1.886 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr14_-_21064182 1.877 SALL2
sal-like 2 (Drosophila)
chr17_+_38186141 1.864 NM_032387
WNK4
WNK lysine deficient protein kinase 4
chr17_+_75366524 1.854 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr20_-_30535045 1.851 C20orf112
chromosome 20 open reading frame 112
chr2_+_10101081 1.831 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr15_+_78232232 1.820 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr11_+_46359781 1.819 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr7_-_154425510 1.819 NM_007349
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chr16_+_88422354 1.813 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr12_+_54910767 1.803 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr19_+_61344501 1.800 ZNF444
zinc finger protein 444
chr2_+_170298487 1.798


chr14_-_37134191 1.784 NM_004496
FOXA1
forkhead box A1
chr10_+_102719239 1.784 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr19_-_2672337 1.782 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr20_-_3102169 1.779 ProSAPiP1
ProSAPiP1 protein
chr7_-_100325209 1.772 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr20_+_44083667 1.772 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr19_-_1966628 1.772 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr22_-_18384251 1.771 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr12_-_123914375 1.760 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr17_+_26060617 1.754


chr17_-_77512346 1.753 NM_178493
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr8_+_27404508 1.748 NM_001979
EPHX2
epoxide hydrolase 2, cytoplasmic
chr16_-_88295595 1.745 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr9_+_132961723 1.738 AIF1L
allograft inflammatory factor 1-like
chr5_+_139008209 1.734 NM_016463
CXXC5
CXXC finger protein 5
chr11_-_64268841 1.733 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_218972721 1.733 NM_021198
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr21_+_46473494 1.723 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr7_-_100331417 1.714 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr17_-_38081967 1.700 NM_024927
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr5_-_134397740 1.698 NM_002653
PITX1
paired-like homeodomain 1
chr19_-_14177980 1.697 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr6_+_33495824 1.697 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr16_+_49139694 1.691 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr19_+_13090101 1.677 NM_052876
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr19_+_18069596 1.677 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr19_+_10404110 1.676 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr16_-_30042083 1.673 NM_001040056
NM_001109891
NM_002746
MAPK3


mitogen-activated protein kinase 3


chr1_+_945472 1.672 AGRN
agrin
chr16_+_29725597 1.672


chr11_+_117812282 1.666 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr12_+_100615530 1.664 NM_020244
CHPT1
choline phosphotransferase 1
chr12_-_61615124 1.661 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_+_26895108 1.660 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr19_+_7891193 1.656 NM_003083
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chrX_+_152643516 1.640 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr7_-_102044374 1.630 RASA4
RAS p21 protein activator 4
chr11_+_550868 1.629 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr6_+_7052798 1.629 NM_001168344
RREB1
ras responsive element binding protein 1
chr19_+_59064795 1.624 MYADM
myeloid-associated differentiation marker
chr12_-_123914219 1.614 SCARB1
scavenger receptor class B, member 1
chr16_-_2186465 1.614 NM_020764
CASKIN1
CASK interacting protein 1
chr2_+_74635019 1.601 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr20_-_30636535 1.599 LOC284804
hypothetical protein LOC284804
chr19_+_40224457 1.596 HPN
hepsin
chr19_+_47480445 1.593 NM_015125
CIC
capicua homolog (Drosophila)
chr9_+_132961683 1.591 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr15_-_20637731 1.579 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr19_+_14405216 1.574 PKN1
protein kinase N1
chr22_-_30072217 1.556 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr19_-_50688310 1.552 NM_206901
RTN2
reticulon 2
chr7_+_151792052 1.550 LOC100128822
hypothetical LOC100128822
chr2_-_32089608 1.546 MEMO1
mediator of cell motility 1
chr19_-_18409788 1.544 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr19_+_40900965 1.541 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr19_+_61344341 1.541 NM_018337
ZNF444
zinc finger protein 444
chr7_+_72720256 1.540 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr20_-_62151216 1.539 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr1_-_1283770 1.539 NM_032348
MXRA8
matrix-remodelling associated 8
chr1_-_233879617 1.531 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr20_-_49592444 1.529 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_945399 1.528


chr7_-_150283794 1.520 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr16_+_2503676 1.520 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr11_+_46359855 1.514 MDK
midkine (neurite growth-promoting factor 2)
chr2_+_42128521 1.513 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_-_41480368 1.513 SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr4_-_6253152 1.510 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr17_-_37586716 1.509 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr16_+_2503915 1.507 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr22_-_30072329 1.503 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_-_51138306 1.500 NM_001080430
TOX3
TOX high mobility group box family member 3
chr16_-_30014993 1.500 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr2_+_112372671 1.490 MERTK
c-mer proto-oncogene tyrosine kinase
chr20_+_30410447 1.489 ASXL1
additional sex combs like 1 (Drosophila)
chr14_+_74964261 1.488 NM_001135047
JDP2
Jun dimerization protein 2
chr12_+_56291484 1.487 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr15_+_38520594 1.485 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr17_-_3743019 1.482 CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr17_+_71097147 1.478 MYO15B
myosin XVB pseudogene
chr16_-_1369613 1.476 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr2_-_61551350 1.476 NM_014709
USP34
ubiquitin specific peptidase 34
chr11_-_65082208 1.476 NM_001130144
NM_001164266
NM_021070
LTBP3


latent transforming growth factor beta binding protein 3


chr7_-_102044419 1.474 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr5_-_176671897 1.462 NM_001142935
NM_031300
MXD3

MAX dimerization protein 3

chr16_-_371823 1.458 NM_021259
TMEM8A
transmembrane protein 8A
chr11_+_46359836 1.456 MDK
midkine (neurite growth-promoting factor 2)
chr19_+_53951155 1.454 NM_019113
FGF21
fibroblast growth factor 21
chr19_+_54708389 1.454 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr2_-_42574587 1.447 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr16_+_29725665 1.441


chr6_+_169866714 1.439 LOC729088
hypothetical LOC729088
chr10_+_76256305 1.437 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr12_-_123914299 1.436 SCARB1
scavenger receptor class B, member 1
chr16_-_87280380 1.423 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr8_-_146023228 1.417 LOC100130027
hypothetical LOC100130027

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 1.34e-23 GO:0009987 cellular process
1.13 6.43e-18 GO:0044237 cellular metabolic process
1.15 3.20e-15 GO:0044260 cellular macromolecule metabolic process
1.57 2.38e-14 GO:0016568 chromatin modification
1.16 6.34e-12 GO:0031323 regulation of cellular metabolic process
1.10 2.00e-11 GO:0008152 metabolic process
1.16 2.24e-11 GO:0016043 cellular component organization
1.16 2.80e-11 GO:0060255 regulation of macromolecule metabolic process
1.15 3.22e-11 GO:0080090 regulation of primary metabolic process
1.10 8.93e-11 GO:0044238 primary metabolic process
1.18 1.62e-10 GO:0010468 regulation of gene expression
1.14 2.24e-10 GO:0019222 regulation of metabolic process
1.70 2.33e-10 GO:0016569 covalent chromatin modification
1.70 3.59e-10 GO:0016570 histone modification
1.09 5.53e-10 GO:0050794 regulation of cellular process
1.15 8.48e-10 GO:0071840 cellular component organization or biogenesis
1.08 1.66e-09 GO:0065007 biological regulation
1.17 3.41e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 5.69e-09 GO:0006464 protein modification process
1.17 7.21e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.16 7.89e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 1.01e-08 GO:0051252 regulation of RNA metabolic process
1.11 1.32e-08 GO:0043170 macromolecule metabolic process
1.15 1.62e-08 GO:0034641 cellular nitrogen compound metabolic process
1.16 1.71e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.17 2.00e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.08 2.58e-08 GO:0050789 regulation of biological process
1.14 3.13e-08 GO:0006807 nitrogen compound metabolic process
1.40 6.23e-08 GO:0006325 chromatin organization
1.16 7.31e-08 GO:0071842 cellular component organization at cellular level
1.17 1.40e-07 GO:0006355 regulation of transcription, DNA-dependent
1.15 2.02e-07 GO:0009889 regulation of biosynthetic process
1.18 2.04e-07 GO:0043412 macromolecule modification
1.15 2.27e-07 GO:0031326 regulation of cellular biosynthetic process
1.17 8.20e-07 GO:0048523 negative regulation of cellular process
1.15 8.63e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.26 9.59e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.32 2.92e-06 GO:0051276 chromosome organization
1.19 4.19e-06 GO:0006996 organelle organization
1.15 4.23e-06 GO:0044267 cellular protein metabolic process
1.16 4.80e-06 GO:0090304 nucleic acid metabolic process
1.15 1.26e-05 GO:0048519 negative regulation of biological process
1.30 2.65e-05 GO:0010629 negative regulation of gene expression
1.31 5.40e-05 GO:0051253 negative regulation of RNA metabolic process
1.24 5.70e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.31 6.52e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.14 6.79e-05 GO:0048522 positive regulation of cellular process
1.22 9.67e-05 GO:0007049 cell cycle
1.23 2.42e-04 GO:0006351 transcription, DNA-dependent
1.22 2.76e-04 GO:0009892 negative regulation of metabolic process
1.28 3.50e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 4.21e-04 GO:0007399 nervous system development
1.26 5.26e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.12 5.49e-04 GO:0048518 positive regulation of biological process
1.27 5.66e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.19 6.11e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.27 6.14e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.22 7.72e-04 GO:0031324 negative regulation of cellular metabolic process
1.16 1.11e-03 GO:0034645 cellular macromolecule biosynthetic process
1.20 1.13e-03 GO:0051246 regulation of protein metabolic process
1.15 1.22e-03 GO:0016070 RNA metabolic process
1.20 1.30e-03 GO:0032268 regulation of cellular protein metabolic process
1.15 1.39e-03 GO:0009059 macromolecule biosynthetic process
1.25 1.40e-03 GO:0009890 negative regulation of biosynthetic process
1.25 1.94e-03 GO:0010628 positive regulation of gene expression
1.12 2.01e-03 GO:0044249 cellular biosynthetic process
1.24 2.26e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.33 3.30e-03 GO:0018193 peptidyl-amino acid modification
1.39 3.67e-03 GO:0016567 protein ubiquitination
1.25 4.13e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.12 4.26e-03 GO:0009058 biosynthetic process
1.34 4.35e-03 GO:0070647 protein modification by small protein conjugation or removal
1.24 5.08e-03 GO:0051254 positive regulation of RNA metabolic process
1.22 5.75e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 6.10e-03 GO:0030154 cell differentiation
1.70 6.33e-03 GO:0006338 chromatin remodeling
1.17 8.47e-03 GO:0009893 positive regulation of metabolic process
1.20 9.50e-03 GO:0048468 cell development
1.14 9.61e-03 GO:0010467 gene expression
1.64 9.62e-03 GO:0018205 peptidyl-lysine modification
1.26 1.22e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.17 1.36e-02 GO:0031325 positive regulation of cellular metabolic process
1.72 1.37e-02 GO:0006475 internal protein amino acid acetylation
1.10 1.40e-02 GO:0048856 anatomical structure development
1.21 1.40e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.16 1.54e-02 GO:0033036 macromolecule localization
1.21 1.58e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.35 1.80e-02 GO:0032446 protein modification by small protein conjugation
1.39 2.06e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.12 2.10e-02 GO:0048869 cellular developmental process
1.70 2.36e-02 GO:0018394 peptidyl-lysine acetylation
1.18 2.46e-02 GO:0022607 cellular component assembly
1.19 2.94e-02 GO:0048699 generation of neurons
1.29 2.97e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.65 3.36e-02 GO:0006473 protein acetylation
1.20 3.85e-02 GO:0022402 cell cycle process
1.15 3.87e-02 GO:0009966 regulation of signal transduction
1.69 4.06e-02 GO:0018393 internal peptidyl-lysine acetylation
1.08 4.18e-02 GO:0032502 developmental process
1.14 4.63e-02 GO:0023051 regulation of signaling
1.10 4.78e-02 GO:0048731 system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 8.37e-43 GO:0044424 intracellular part
1.10 2.49e-42 GO:0005622 intracellular
1.13 2.56e-35 GO:0043227 membrane-bounded organelle
1.12 4.44e-35 GO:0043231 intracellular membrane-bounded organelle
1.11 1.99e-31 GO:0043229 intracellular organelle
1.11 2.33e-31 GO:0043226 organelle
1.16 7.91e-28 GO:0005634 nucleus
1.11 1.04e-23 GO:0005737 cytoplasm
1.25 4.49e-19 GO:0044428 nuclear part
1.24 4.80e-14 GO:0031981 nuclear lumen
1.11 3.41e-13 GO:0044444 cytoplasmic part
1.21 3.46e-13 GO:0005829 cytosol
1.20 3.55e-13 GO:0043233 organelle lumen
1.12 4.02e-13 GO:0044446 intracellular organelle part
1.20 6.43e-13 GO:0070013 intracellular organelle lumen
1.11 7.53e-13 GO:0044422 organelle part
1.20 1.25e-12 GO:0031974 membrane-enclosed lumen
1.23 3.42e-09 GO:0005654 nucleoplasm
1.03 8.95e-07 GO:0044464 cell part
1.03 9.97e-07 GO:0005623 cell
1.25 3.31e-05 GO:0044451 nucleoplasm part
1.12 5.65e-05 GO:0043234 protein complex
1.27 1.65e-04 GO:0005694 chromosome
1.65 3.53e-04 GO:0016585 chromatin remodeling complex
1.10 5.35e-04 GO:0032991 macromolecular complex
1.60 7.83e-04 GO:0005925 focal adhesion
1.66 7.86e-04 GO:0000790 nuclear chromatin
1.26 2.91e-03 GO:0044427 chromosomal part
1.54 3.78e-03 GO:0030055 cell-substrate junction
1.38 4.23e-03 GO:0000228 nuclear chromosome
1.20 4.51e-03 GO:0031410 cytoplasmic vesicle
1.43 5.07e-03 GO:0070161 anchoring junction
1.19 5.55e-03 GO:0031982 vesicle
1.20 5.82e-03 GO:0031988 membrane-bounded vesicle
1.20 6.35e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.52 8.95e-03 GO:0005924 cell-substrate adherens junction
1.13 1.27e-02 GO:0012505 endomembrane system
1.44 1.29e-02 GO:0000151 ubiquitin ligase complex
1.34 1.35e-02 GO:0000785 chromatin
1.40 1.37e-02 GO:0044454 nuclear chromosome part
1.20 1.42e-02 GO:0015630 microtubule cytoskeleton
1.41 2.44e-02 GO:0005912 adherens junction
1.16 4.13e-02 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.08e-28 GO:0005515 protein binding
1.08 3.27e-27 GO:0005488 binding
1.15 3.42e-10 GO:0003676 nucleic acid binding
1.26 3.96e-08 GO:0030528 transcription regulator activity
1.16 1.26e-07 GO:0003677 DNA binding
1.29 1.68e-06 GO:0043565 sequence-specific DNA binding
1.15 2.15e-06 GO:0000166 nucleotide binding
1.25 2.60e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.23 4.18e-06 GO:0001071 nucleic acid binding transcription factor activity
1.23 4.18e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.26 6.58e-06 GO:0019899 enzyme binding
1.26 8.34e-06 GO:0016301 kinase activity
1.34 1.08e-05 GO:0019904 protein domain specific binding
1.41 2.23e-05 GO:0008134 transcription factor binding
1.25 9.08e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.43 1.13e-04 GO:0019787 small conjugating protein ligase activity
1.43 3.71e-04 GO:0004842 ubiquitin-protein ligase activity
1.15 5.69e-04 GO:0016740 transferase activity
1.35 1.16e-03 GO:0016564 transcription repressor activity
1.33 1.75e-03 GO:0016563 transcription activator activity
1.07 2.22e-03 GO:0003824 catalytic activity
1.29 5.18e-03 GO:0003712 transcription cofactor activity
1.66 5.94e-03 GO:0042393 histone binding
1.29 6.51e-03 GO:0000988 protein binding transcription factor activity
1.29 6.51e-03 GO:0000989 transcription factor binding transcription factor activity
1.34 7.03e-03 GO:0016881 acid-amino acid ligase activity
1.24 7.34e-03 GO:0008092 cytoskeletal protein binding
1.35 9.16e-03 GO:0003702 RNA polymerase II transcription factor activity
1.32 9.81e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.14 1.07e-02 GO:0030554 adenyl nucleotide binding
1.14 1.23e-02 GO:0032559 adenyl ribonucleotide binding
1.26 1.27e-02 GO:0004674 protein serine/threonine kinase activity
1.12 1.72e-02 GO:0032553 ribonucleotide binding
1.12 1.72e-02 GO:0032555 purine ribonucleotide binding
1.14 1.82e-02 GO:0005524 ATP binding
1.12 1.82e-02 GO:0017076 purine nucleotide binding
1.12 2.00e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.11 2.03e-02 GO:0008270 zinc ion binding
1.19 2.07e-02 GO:0042802 identical protein binding
1.22 2.29e-02 GO:0004672 protein kinase activity
1.38 3.07e-02 GO:0003682 chromatin binding
1.29 3.70e-02 GO:0003779 actin binding
1.07 4.07e-02 GO:0043169 cation binding
1.40 4.21e-02 GO:0000287 magnesium ion binding
1.07 4.58e-02 GO:0043167 ion binding