Motif ID: TFEB.p2

Z-value: 2.249


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41781655-0.485.9e-02Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_27162688 8.339 NM_006896
HOXA7
homeobox A7
chr5_+_34692124 6.175 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr2_+_223625105 5.575 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr5_+_34692239 5.422 RAI14
retinoic acid induced 14
chr5_+_34692352 5.130 NM_001145520
RAI14
retinoic acid induced 14
chr1_-_68470585 4.849 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr10_-_14090459 4.827 FRMD4A
FERM domain containing 4A
chr9_-_16860719 4.816 NM_017637
BNC2
basonuclin 2
chr22_+_34107051 4.535 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr6_+_87921980 4.515 NM_015021
ZNF292
zinc finger protein 292
chr2_+_85834111 4.469 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr22_+_34107087 4.456 HMOX1
heme oxygenase (decycling) 1
chr1_-_152459667 4.439 C1orf43
chromosome 1 open reading frame 43
chr13_+_112999462 4.328 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr7_-_47588652 4.109 TNS3
tensin 3
chr6_-_80713589 3.987 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr7_-_47588160 3.976 TNS3
tensin 3
chrX_-_34585287 3.747 NM_031442
TMEM47
transmembrane protein 47
chr1_-_152459506 3.688 C1orf43
chromosome 1 open reading frame 43
chr1_+_201364050 3.677 ADORA1
adenosine A1 receptor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
7.47 4.42e-02 GO:0032006 regulation of TOR signaling cascade
7.11 1.26e-03 GO:0015682 ferric iron transport
7.11 1.26e-03 GO:0033572 transferrin transport
6.32 4.56e-02 GO:0007040 lysosome organization
5.33 3.11e-03 GO:0007033 vacuole organization
4.78 4.38e-03 GO:0048704 embryonic skeletal system morphogenesis
4.05 6.85e-03 GO:0048706 embryonic skeletal system development
3.24 1.17e-02 GO:0048705 skeletal system morphogenesis
3.05 6.34e-03 GO:0009952 anterior/posterior pattern formation
2.04 1.10e-02 GO:0034613 cellular protein localization
2.02 1.30e-02 GO:0070727 cellular macromolecule localization
1.92 7.56e-06 GO:0008104 protein localization
1.88 9.53e-04 GO:0015031 protein transport
1.84 1.82e-03 GO:0045184 establishment of protein localization
1.82 9.29e-03 GO:0046907 intracellular transport
1.80 1.42e-05 GO:0033036 macromolecule localization
1.68 1.91e-03 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
8.89 4.66e-02 GO:0030897 HOPS complex
8.54 6.02e-04 GO:0033176 proton-transporting V-type ATPase complex
4.67 4.25e-04 GO:0031902 late endosome membrane
3.98 1.18e-07 GO:0005774 vacuolar membrane
3.83 3.82e-05 GO:0005770 late endosome
3.81 3.50e-07 GO:0044437 vacuolar part
3.60 5.43e-03 GO:0042470 melanosome
3.60 5.43e-03 GO:0048770 pigment granule
3.53 5.68e-04 GO:0005765 lysosomal membrane
3.41 8.82e-05 GO:0005769 early endosome
3.32 8.30e-11 GO:0005773 vacuole
2.93 2.55e-06 GO:0000323 lytic vacuole
2.93 2.55e-06 GO:0005764 lysosome
2.93 7.06e-06 GO:0010008 endosome membrane
2.90 8.65e-06 GO:0044440 endosomal part
2.53 3.96e-07 GO:0005768 endosome
1.72 2.43e-02 GO:0044451 nucleoplasm part
1.41 8.51e-03 GO:0044428 nuclear part
1.28 4.41e-05 GO:0044422 organelle part
1.28 7.25e-05 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.22 1.41e-04 GO:0005515 protein binding