Motif ID: MYBL2.p2

Z-value: 1.645


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYBL2chr20_+_41729122-0.572.2e-02Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_155686750 4.270 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr3_+_158637273 4.117 NM_002852
PTX3
pentraxin 3, long
chrX_-_33139349 4.004 NM_004006
DMD
dystrophin
chr2_-_198248828 3.956 NM_144629
RFTN2
raftlin family member 2
chr15_+_41597097 3.948 NM_002373
MAP1A
microtubule-associated protein 1A
chr2_+_170074457 3.630 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr3_+_100840129 3.147 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr17_-_15495534 3.117 TRIM16
tripartite motif containing 16
chr11_-_85107569 3.098 NM_206929
SYTL2
synaptotagmin-like 2
chr15_+_55298908 2.889 NM_207040
TCF12
transcription factor 12
chr10_+_17310263 2.803 NM_003380
VIM
vimentin
chr1_-_197173159 2.706 LOC100131234
familial acute myelogenous leukemia related factor
chr9_+_119506428 2.616 TLR4
toll-like receptor 4
chr3_-_15814678 2.589 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr9_+_119506446 2.588 TLR4
toll-like receptor 4
chr11_-_85108030 2.584 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr9_-_72219359 2.437 NM_001206
KLF9
Kruppel-like factor 9
chr5_-_39460787 2.410 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr3_-_115960807 2.398 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr1_-_191422346 2.358 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_-_189752575 2.351 NM_000393
COL5A2
collagen, type V, alpha 2
chr10_+_17310475 2.328 VIM
vimentin
chr17_-_46479127 2.260 SPAG9
sperm associated antigen 9
chr5_-_39460687 2.245 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr9_+_71848316 2.189 NM_153267
MAMDC2
MAM domain containing 2
chr5_-_39461054 2.147 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_-_40537002 2.012 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr15_+_47502666 1.899 NM_002009
FGF7
fibroblast growth factor 7
chr1_+_165330710 1.867 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr2_+_151922350 1.798 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr4_+_120276386 1.774 NM_016599
MYOZ2
myozenin 2
chr8_-_122722674 1.739 NM_005328
HAS2
hyaluronan synthase 2
chr12_+_32578513 1.694 FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_+_18464090 1.656 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr15_+_65205107 1.590 NM_001145102
SMAD3
SMAD family member 3
chr6_+_152053323 1.574 NM_001122742
ESR1
estrogen receptor 1
chr3_-_113841448 1.572 CCDC80
coiled-coil domain containing 80
chr12_+_55201854 1.535 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr3_+_35696119 1.521 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr16_+_14187965 1.510 MKL2
MKL/myocardin-like 2
chr9_-_94338072 1.492 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr5_+_36642424 1.477 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_208472817 1.460 NM_019605
SERTAD4
SERTA domain containing 4
chr9_-_72218098 1.456 KLF9
Kruppel-like factor 9
chr7_+_120416103 1.438 C7orf58
chromosome 7 open reading frame 58
chr4_+_3341521 1.376 NM_198227
RGS12
regulator of G-protein signaling 12
chr5_+_155686333 1.369 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr8_+_107807415 1.355 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_113841967 1.351 CCDC80
coiled-coil domain containing 80
chr1_+_216585298 1.303 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr9_+_71848555 1.300 MAMDC2
MAM domain containing 2
chr13_+_100902942 1.291 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr21_+_29439768 1.259 C21orf7
chromosome 21 open reading frame 7
chrX_-_10548458 1.249 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr9_+_119506274 1.238 NM_138554
TLR4
toll-like receptor 4
chr6_-_117853710 1.208 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr12_+_118515646 1.207 NM_001136534
TMEM233
transmembrane protein 233
chr1_+_557269 1.200


chr3_-_113841941 1.193 CCDC80
coiled-coil domain containing 80
chr2_-_152299229 1.192 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr5_-_54317102 1.189 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr17_+_7753428 1.151 CHD3
chromodomain helicase DNA binding protein 3
chr12_+_76749199 1.137 NM_014903
NAV3
neuron navigator 3
chr11_-_10487212 1.130 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr11_-_111287657 1.123 NM_001885
CRYAB
crystallin, alpha B
chrX_+_135106578 1.116 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr5_+_36644187 1.107 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_48902692 1.067 NM_001113547
LIMA1
LIM domain and actin binding 1
chrX_-_77801480 1.053 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr1_+_159943385 1.042 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr7_+_28497272 1.038 CREB5
cAMP responsive element binding protein 5
chr1_-_143786993 1.032 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr10_-_95231933 1.026 NM_013451
NM_133337
MYOF

myoferlin

chr7_+_120416680 1.026 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr12_-_16649211 1.019 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_15145001 1.010 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr3_-_113842133 0.997 CCDC80
coiled-coil domain containing 80
chr14_-_88086559 0.995 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr7_+_93388951 0.969 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr1_+_146843980 0.953 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr14_+_57964148 0.946


chr14_+_58174489 0.940 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr3_+_137167153 0.908 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr6_-_152744022 0.900 SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_+_160964574 0.899 SCHIP1
schwannomin interacting protein 1
chr15_-_23201740 0.895 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr12_-_74764677 0.890 NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_168898898 0.876 PRRX1
paired related homeobox 1
chr11_+_32994303 0.874 NM_139160
DEPDC7
DEP domain containing 7
chr1_+_556968 0.865


chr19_+_24061717 0.858 NM_203282
ZNF254
zinc finger protein 254
chr3_-_113841200 0.835 CCDC80
coiled-coil domain containing 80
chrX_+_74410774 0.827


chr4_+_148621694 0.824 EDNRA
endothelin receptor type A
chr1_+_143807748 0.820 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr12_-_26169074 0.818 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_+_99884018 0.809 NM_017734
PALMD
palmdelphin
chr3_-_113842652 0.770 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr9_+_115396020 0.760 NM_144489
RGS3
regulator of G-protein signaling 3
chr11_-_35503720 0.757 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr3_-_113842553 0.756 CCDC80
coiled-coil domain containing 80
chr21_+_39745649 0.748 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr12_-_74765004 0.747 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr5_-_90645974 0.739 LOC100505994
hypothetical LOC100505994
chr1_+_559618 0.736


chr4_-_177427252 0.732 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr5_-_94443300 0.726 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr4_-_74307637 0.714 ANKRD17
ankyrin repeat domain 17
chr21_+_36429079 0.713 NM_001236
CBR3
carbonyl reductase 3
chr10_-_92670764 0.711 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr5_-_94442941 0.701 MCTP1
multiple C2 domains, transmembrane 1
chr6_-_101018271 0.691 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr9_+_117955890 0.687 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr2_+_190710730 0.677 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chrX_-_21686079 0.670 NM_014332
SMPX
small muscle protein, X-linked
chr7_-_13997574 0.666 NM_001163148
ETV1
ets variant 1
chr1_-_153209625 0.666 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr5_-_79982584 0.652 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr6_-_169392771 0.652


chr10_+_104525877 0.643 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr21_+_45396903 0.634 ADARB1
adenosine deaminase, RNA-specific, B1
chr1_-_21373816 0.629 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_+_29297806 0.629 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr11_+_65024889 0.627 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr4_+_120167264 0.627 SYNPO2
synaptopodin 2
chr8_-_95343696 0.626 GEM
GTP binding protein overexpressed in skeletal muscle
chr2_-_227952249 0.621 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr5_+_40877053 0.616 NM_032587
CARD6
caspase recruitment domain family, member 6
chr1_-_171838802 0.616 NM_178527
SLC9A11
solute carrier family 9, member 11
chr19_-_13808101 0.615 LOC284454
hypothetical LOC284454
chr10_+_44726635 0.606 NM_001123376
TMEM72
transmembrane protein 72
chr10_-_106088151 0.602 ITPRIP
inositol 1,4,5-triphosphate receptor interacting protein
chr11_-_85103438 0.594 NM_032379
SYTL2
synaptotagmin-like 2
chr9_+_96806235 0.592 C9orf3
chromosome 9 open reading frame 3
chr1_+_226352179 0.587 ARF1
ADP-ribosylation factor 1
chr3_-_113842350 0.572 CCDC80
coiled-coil domain containing 80
chr7_+_104539548 0.571 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_+_143326315 0.564 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr7_+_129771865 0.560 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr12_+_79362256 0.560 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr3_+_33293915 0.559 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr6_-_127822227 0.558 NM_014702
KIAA0408
KIAA0408
chr10_-_92671005 0.558 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_98315090 0.554 TM9SF3
transmembrane 9 superfamily member 3
chr4_-_122357104 0.552 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr3_-_113842255 0.549 CCDC80
coiled-coil domain containing 80
chr4_-_151993422 0.523


chr11_+_64950074 0.523 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_+_20269239 0.505 NM_000929
PLA2G5
phospholipase A2, group V
chr16_+_55373241 0.502 NUP93
nucleoporin 93kDa
chr15_-_74941339 0.499 NM_001145923
SCAPER
S-phase cyclin A-associated protein in the ER
chr12_+_5411534 0.499 NM_001102654
NTF3
neurotrophin 3
chr4_-_148086413 0.496 NM_031956
TTC29
tetratricopeptide repeat domain 29
chr10_-_69762654 0.495 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr10_-_32707549 0.493 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_195818927 0.493 DENND1B
DENN/MADD domain containing 1B
chr11_+_27019084 0.486 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr18_+_19286784 0.485 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr14_-_74669864 0.474 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr5_-_156935283 0.460


chr1_-_115102084 0.460 CSDE1
cold shock domain containing E1, RNA-binding
chr2_+_127130209 0.459 GYPC
glycophorin C (Gerbich blood group)
chr17_+_46176105 0.453 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr4_+_148621567 0.450 EDNRA
endothelin receptor type A
chr2_+_84597087 0.448 NM_001370
DNAH6
dynein, axonemal, heavy chain 6
chr9_+_4782974 0.444 RCL1
RNA terminal phosphate cyclase-like 1
chr9_-_36266930 0.438 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr5_+_162862808 0.436 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr5_-_58607673 0.435 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_115102109 0.433 CSDE1
cold shock domain containing E1, RNA-binding
chr19_-_60528480 0.433 NM_001085488
TMEM150B
transmembrane protein 150B
chr1_+_559129 0.433


chr1_-_115102124 0.433 CSDE1
cold shock domain containing E1, RNA-binding
chr4_+_77575276 0.432 NM_020859
SHROOM3
shroom family member 3
chr8_-_17599438 0.430 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr8_+_32905027 0.427


chr6_-_111995213 0.427 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr3_+_131547048 0.423 NM_153264
COL6A5
collagen, type VI, alpha 5
chr12_+_54400417 0.422 NM_002905
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr17_-_45619038 0.420 COL1A1
collagen, type I, alpha 1
chr8_-_95343716 0.418 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr19_+_53520439 0.417 NM_001425
EMP3
epithelial membrane protein 3
chr1_-_115102106 0.417 CSDE1
cold shock domain containing E1, RNA-binding
chr3_-_188935363 0.408 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr10_+_99322187 0.407 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr1_+_242283129 0.405 NM_006352
ZNF238
zinc finger protein 238
chr17_+_39990124 0.404 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr1_-_85816520 0.403 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_41163680 0.402 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr2_+_127130148 0.401 NM_002101
NM_016815
GYPC

glycophorin C (Gerbich blood group)

chr1_+_19807168 0.400


chr1_-_94147537 0.399 GCLM
glutamate-cysteine ligase, modifier subunit
chr11_+_6762823 0.398 NM_001004489
OR2AG1
olfactory receptor, family 2, subfamily AG, member 1
chrX_-_11194015 0.397 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr10_-_28611020 0.397 NM_173496
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr19_+_53520632 0.393 EMP3
epithelial membrane protein 3
chr1_-_103269356 0.389 COL11A1
collagen, type XI, alpha 1
chr13_+_96797290 0.387


chr6_-_112186977 0.386 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr4_+_41234944 0.383 LIMCH1
LIM and calponin homology domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 3.72e-02 GO:0003008 system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.48 4.10e-03 GO:0030016 myofibril
1.31 4.31e-03 GO:0005886 plasma membrane
1.30 5.10e-03 GO:0071944 cell periphery
3.28 8.64e-03 GO:0043292 contractile fiber
3.34 1.20e-02 GO:0044449 contractile fiber part
3.34 3.87e-02 GO:0030017 sarcomere

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.30 2.73e-03 GO:0004984 olfactory receptor activity