Motif ID: ZFP161.p2

Z-value: 1.792


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZFP161chr18_-_52860130.273.2e-01Click!


Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_725522 4.020 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr9_+_126060063 2.315 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr5_-_88214720 2.309 MEF2C
myocyte enhancer factor 2C
chr9_+_126060108 2.199 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr5_+_14493905 2.055 TRIO
triple functional domain (PTPRF interacting)
chr2_+_207016525 2.017 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr12_-_31635089 1.955 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr3_+_61522310 1.949 PTPRG
protein tyrosine phosphatase, receptor type, G
chr9_+_126060072 1.921 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr5_-_88215034 1.900 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr18_-_21184824 1.879


chr2_+_56265260 1.817


chr9_+_126060407 1.805


chr3_+_61522219 1.800 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr9_+_126059603 1.793 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr9_+_126060283 1.715 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr3_-_151171190 1.674 NM_002628
NM_053024
PFN2

profilin 2

chr8_+_121892719 1.652


chr2_+_149895274 1.640 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr10_+_122206455 1.638 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr10_+_11099860 1.630 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr2_+_56264627 1.560 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr2_+_71547325 1.550 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr10_+_11100111 1.497 CELF2
CUGBP, Elav-like family member 2
chr1_+_229829143 1.479 NM_001012957
NM_001012958
NM_001012959
NM_001164537
NM_001164538
NM_001164539
NM_001164540
NM_001164541
NM_001164542
NM_001164544
NM_001164545
NM_001164546
NM_001164547
NM_001164548
NM_001164549
NM_001164550
NM_001164551
NM_001164552
NM_001164553
NM_001164554
NM_001164555
NM_001164556
NM_018662
DISC1






















disrupted in schizophrenia 1






















chr16_-_71639670 1.465 NM_006885
ZFHX3
zinc finger homeobox 3
chr10_+_11100075 1.452 CELF2
CUGBP, Elav-like family member 2
chr1_-_212791597 1.448 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_85703321 1.443 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_28469864 1.440 FOSL2
FOS-like antigen 2
chr9_-_21984414 1.438 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr14_-_73106243 1.391


chr22_-_27405708 1.383 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr15_-_61680003 1.371 LOC100130855
hypothetical LOC100130855
chr8_-_125809831 1.365 NM_014751
MTSS1
metastasis suppressor 1
chr2_+_203901160 1.355 NM_005759
ABI2
abl-interactor 2
chr17_-_19711580 1.350 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr17_+_56832255 1.337 TBX2
T-box 2
chr9_-_83493415 1.316 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr13_-_31900218 1.292 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr1_-_85703198 1.287 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_-_55496607 1.280 WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_5952631 1.254 NM_016588
NRN1
neuritin 1
chr2_+_28469850 1.245 FOSL2
FOS-like antigen 2
chr10_-_131652007 1.235 NM_001005463
EBF3
early B-cell factor 3
chr14_+_73105618 1.224 ACOT2
acyl-CoA thioesterase 2
chr3_-_55496370 1.217 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr8_-_125809559 1.202 MTSS1
metastasis suppressor 1
chr5_-_83716346 1.173 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr14_+_73073570 1.169 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr12_+_50271283 1.165 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr2_+_54536780 1.161 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr2_+_241586927 1.156 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr2_+_29191711 1.147 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr7_-_47588266 1.119 TNS3
tensin 3
chr2_-_175255717 1.117 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr12_-_24606616 1.103 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr10_+_90629880 1.097 NM_020799
STAMBPL1
STAM binding protein-like 1
chr2_-_216008689 1.080 FN1
fibronectin 1
chr10_+_124210980 1.068 NM_002775
HTRA1
HtrA serine peptidase 1
chr16_-_71650034 1.062 NM_001164766
ZFHX3
zinc finger homeobox 3
chr6_-_38715567 1.058 BTBD9
BTB (POZ) domain containing 9
chr9_-_21984379 1.056 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr7_-_55607692 1.047 NM_030796
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr9_-_21984329 1.039 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr6_-_143307976 1.035 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr14_-_89155078 1.033 NM_001085471
FOXN3
forkhead box N3
chr19_-_1518875 1.016 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr7_-_55607625 1.008 VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr2_-_161058120 1.006 RBMS1
RNA binding motif, single stranded interacting protein 1
chr9_-_131845277 0.989 NM_015033
FNBP1
formin binding protein 1
chr8_+_30361485 0.985 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr14_+_76297885 0.983 NM_014909
VASH1
vasohibin 1
chr19_+_41788042 0.981 NM_032825
ZNF382
zinc finger protein 382
chr1_+_234372454 0.979 NM_003272
GPR137B
G protein-coupled receptor 137B
chr10_+_124211353 0.979 HTRA1
HtrA serine peptidase 1
chr4_+_145786622 0.978 NM_022475
HHIP
hedgehog interacting protein
chr14_-_64948998 0.978 LOC645431
hypothetical LOC645431
chr13_-_27967215 0.973 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr19_+_41788065 0.956 ZNF382
zinc finger protein 382
chr11_+_86189138 0.956 NM_007173
PRSS23
protease, serine, 23
chr8_-_60194099 0.952 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr5_+_14196287 0.947 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr9_+_130354490 0.944 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr9_-_71476917 0.943 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr7_-_55607598 0.942 VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr19_-_41787999 0.938 NM_001145649
NM_001145650
ZNF529

zinc finger protein 529

chrX_-_34585287 0.933 NM_031442
TMEM47
transmembrane protein 47
chr22_-_30072329 0.931 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr15_+_29406335 0.928 NM_015995
KLF13
Kruppel-like factor 13
chr13_-_43259032 0.922 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr5_-_58370693 0.919 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr13_-_32822759 0.912 STARD13
StAR-related lipid transfer (START) domain containing 13
chr9_-_16860719 0.910 NM_017637
BNC2
basonuclin 2
chr1_+_181259317 0.910


chr3_+_112273464 0.905 NM_015480
PVRL3
poliovirus receptor-related 3
chr17_+_56831951 0.900 NM_005994
TBX2
T-box 2
chr17_+_56832492 0.898 TBX2
T-box 2
chr3_+_112273352 0.881 PVRL3
poliovirus receptor-related 3
chr1_-_212791467 0.881 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr9_-_16860664 0.878 BNC2
basonuclin 2
chr12_-_123617962 0.874 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr6_-_38715613 0.871 BTBD9
BTB (POZ) domain containing 9
chr20_-_43996980 0.867 FLJ40606
hypothetical protein LOC643549
chr6_+_107917965 0.865 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr1_-_143643324 0.863 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr4_-_141896920 0.851 NM_015130
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr7_-_45927263 0.851 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr3_+_44571600 0.849 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr11_+_133444175 0.849 JAM3
junctional adhesion molecule 3
chr20_+_44771532 0.843 NM_030777
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr7_+_78920846 0.841 LOC100505881
hypothetical LOC100505881
chr3_+_151171755 0.840 LOC646903
hypothetical LOC646903
chr2_-_197883569 0.840 ANKRD44
ankyrin repeat domain 44
chr9_-_4289915 0.839 GLIS3
GLIS family zinc finger 3
chr2_-_40532651 0.839 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_+_171558143 0.834 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr5_-_37285160 0.823 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr9_+_127549437 0.819 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr8_-_121892877 0.817 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr17_-_63798851 0.814 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr16_-_73842884 0.812 NM_001170717
NM_014567
BCAR1

breast cancer anti-estrogen resistance 1

chr7_-_27180398 0.812 NM_018951
HOXA10
homeobox A10
chr2_-_236740710 0.811


chr11_+_133444029 0.806 NM_032801
JAM3
junctional adhesion molecule 3
chrX_-_142549984 0.803 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr3_-_126257425 0.802 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr10_+_95743674 0.798 NM_016341
PLCE1
phospholipase C, epsilon 1
chr20_-_43997091 0.798 FLJ40606
hypothetical protein LOC643549
chr15_-_53822468 0.792 NM_173814
PRTG
protogenin
chr6_-_56816403 0.778 DST
dystonin
chr11_+_101485946 0.776 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr5_-_146869613 0.771 DPYSL3
dihydropyrimidinase-like 3
chr9_+_136673534 0.769 COL5A1
collagen, type V, alpha 1
chr11_-_1549719 0.766 NM_004420
DUSP8
dual specificity phosphatase 8
chr6_-_38715901 0.752 NM_001099272
NM_052893
BTBD9

BTB (POZ) domain containing 9

chr7_-_55607564 0.751 VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr10_+_129595349 0.748 PTPRE
protein tyrosine phosphatase, receptor type, E
chr9_+_132700567 0.747 NM_005157
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr20_-_20641122 0.743 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr3_+_160964574 0.743 SCHIP1
schwannomin interacting protein 1
chr1_+_208568811 0.739 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr20_+_11819364 0.738 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr10_+_129595289 0.736 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr3_-_129024665 0.732 NM_001003794
MGLL
monoglyceride lipase
chr1_+_216586199 0.731 TGFB2
transforming growth factor, beta 2
chr9_+_132700462 0.727 ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr1_+_181258952 0.727 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr9_-_4289574 0.724 GLIS3
GLIS family zinc finger 3
chr17_-_40263124 0.720 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr10_-_105604942 0.717 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr11_-_6396864 0.712 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr4_-_22126437 0.711 NM_145290
GPR125
G protein-coupled receptor 125
chr8_+_16929116 0.710 NM_181723
EFHA2
EF-hand domain family, member A2
chr7_-_27136876 0.709 NM_002141
HOXA4
homeobox A4
chr14_+_73105515 0.708 NM_006821
ACOT2
acyl-CoA thioesterase 2
chr22_-_37969897 0.705 PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr6_+_11646472 0.704 NM_001100829
TMEM170B
transmembrane protein 170B
chr11_+_113435506 0.703 ZBTB16
zinc finger and BTB domain containing 16
chr11_+_12355600 0.702 NM_018222
PARVA
parvin, alpha
chr6_-_166960496 0.702 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_29466562 0.698 NM_002742
PRKD1
protein kinase D1
chr13_-_73605914 0.697 NM_007249
KLF12
Kruppel-like factor 12
chr19_-_7244876 0.689 NM_000208
NM_001079817
INSR

insulin receptor

chr17_+_58058774 0.685 MRC2
mannose receptor, C type 2
chr10_+_89409332 0.684 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr19_+_1358664 0.681 DAZAP1
DAZ associated protein 1
chr6_-_166960649 0.680 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_+_61231795 0.679 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chrX_+_51944658 0.678 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr5_+_15553539 0.678 FBXL7
F-box and leucine-rich repeat protein 7
chr5_+_15553288 0.677 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr6_-_16869579 0.676 NM_000332
NM_001128164
ATXN1

ataxin 1

chr17_+_260408 0.673 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr12_+_88627601 0.671 LOC338758
hypothetical LOC338758
chr14_-_91483757 0.671 NM_006329
FBLN5
fibulin 5
chr12_+_58276114 0.669 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr14_-_91483325 0.669 FBLN5
fibulin 5
chr2_-_197883703 0.668 ANKRD44
ankyrin repeat domain 44
chr4_+_72271218 0.668 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr2_-_37752272 0.663 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr14_+_73128162 0.659 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr20_+_34523555 0.658 NM_183006
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr16_-_76026431 0.654 NM_199355
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr8_+_60194328 0.653


chr13_-_76358370 0.653 KCTD12
potassium channel tetramerisation domain containing 12
chr5_-_107034484 0.649 NM_001962
EFNA5
ephrin-A5
chr20_+_8997791 0.648 PLCB4
phospholipase C, beta 4
chr21_-_27261276 0.646 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr15_+_73074882 0.645 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr11_-_6397207 0.645 NM_145689
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr18_-_11138760 0.644 NM_022068
FAM38B
family with sequence similarity 38, member B
chr7_-_47588160 0.642 TNS3
tensin 3
chr5_+_15553736 0.641 FBXL7
F-box and leucine-rich repeat protein 7
chr5_+_10617431 0.636 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr7_+_2638108 0.635 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr7_-_47588652 0.634 TNS3
tensin 3
chr8_+_97575370 0.634 SDC2
syndecan 2
chr13_-_76358433 0.634 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr18_-_16945763 0.631 NM_005406
ROCK1
Rho-associated, coiled-coil containing protein kinase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 8.92e-15 GO:0032502 developmental process
1.31 4.35e-14 GO:0007275 multicellular organismal development
1.50 1.11e-13 GO:0009653 anatomical structure morphogenesis
1.48 8.89e-13 GO:0007399 nervous system development
1.18 2.86e-12 GO:0050794 regulation of cellular process
1.39 5.97e-12 GO:0030154 cell differentiation
1.38 6.06e-12 GO:0048869 cellular developmental process
1.16 2.49e-11 GO:0050789 regulation of biological process
1.60 3.47e-11 GO:0022008 neurogenesis
1.60 1.38e-10 GO:0048699 generation of neurons
1.10 1.92e-10 GO:0009987 cellular process
1.33 1.92e-10 GO:0048522 positive regulation of cellular process
1.28 3.46e-10 GO:0048856 anatomical structure development
1.29 9.67e-10 GO:0048731 system development
1.22 1.17e-09 GO:0044260 cellular macromolecule metabolic process
1.14 6.93e-09 GO:0065007 biological regulation
1.30 7.27e-09 GO:0071842 cellular component organization at cellular level
1.51 1.24e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.30 2.79e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.62 3.54e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.38 4.36e-08 GO:0023051 regulation of signaling
1.40 5.23e-08 GO:0009966 regulation of signal transduction
1.27 1.09e-07 GO:0048518 positive regulation of biological process
1.24 1.10e-07 GO:0016043 cellular component organization
1.34 1.18e-07 GO:0006464 protein modification process
1.27 1.28e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.63 1.32e-07 GO:0000902 cell morphogenesis
1.69 1.66e-07 GO:0000904 cell morphogenesis involved in differentiation
1.16 2.36e-07 GO:0044237 cellular metabolic process
1.28 2.54e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.61 2.59e-07 GO:0032989 cellular component morphogenesis
1.57 3.38e-07 GO:0030182 neuron differentiation
1.28 3.46e-07 GO:0010468 regulation of gene expression
1.49 4.92e-07 GO:0048468 cell development
1.23 4.98e-07 GO:0060255 regulation of macromolecule metabolic process
1.66 6.46e-07 GO:0032990 cell part morphogenesis
1.74 7.96e-07 GO:0009968 negative regulation of signal transduction
1.72 1.10e-06 GO:0007409 axonogenesis
1.70 1.17e-06 GO:0048812 neuron projection morphogenesis
1.65 1.34e-06 GO:0048858 cell projection morphogenesis
1.29 1.62e-06 GO:0048523 negative regulation of cellular process
1.22 1.88e-06 GO:0071840 cellular component organization or biogenesis
1.61 1.95e-06 GO:0048666 neuron development
1.65 2.43e-06 GO:0031175 neuron projection development
1.56 2.93e-06 GO:0030030 cell projection organization
1.28 3.24e-06 GO:0051252 regulation of RNA metabolic process
1.17 3.42e-06 GO:0043170 macromolecule metabolic process
1.31 3.55e-06 GO:0043412 macromolecule modification
1.21 4.13e-06 GO:0031323 regulation of cellular metabolic process
1.43 5.44e-06 GO:0006793 phosphorus metabolic process
1.43 5.44e-06 GO:0006796 phosphate metabolic process
1.21 6.14e-06 GO:0080090 regulation of primary metabolic process
1.68 6.17e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.25 6.33e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 1.15e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.55 1.20e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.25 1.22e-05 GO:0031326 regulation of cellular biosynthetic process
1.24 1.40e-05 GO:0009889 regulation of biosynthetic process
1.24 1.50e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.27 1.60e-05 GO:0006355 regulation of transcription, DNA-dependent
1.49 1.85e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52 1.92e-05 GO:0045595 regulation of cell differentiation
1.75 2.23e-05 GO:0007411 axon guidance
1.58 2.42e-05 GO:0051253 negative regulation of RNA metabolic process
1.47 2.66e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.64 2.80e-05 GO:0023057 negative regulation of signaling
1.45 2.85e-05 GO:0040011 locomotion
1.51 2.86e-05 GO:0009890 negative regulation of biosynthetic process
1.52 2.93e-05 GO:0051254 positive regulation of RNA metabolic process
1.51 2.98e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.64 3.28e-05 GO:0010648 negative regulation of cell communication
1.58 3.72e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.53 4.45e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.53 5.23e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 5.75e-05 GO:0050793 regulation of developmental process
1.53 6.63e-05 GO:0010629 negative regulation of gene expression
1.13 7.61e-05 GO:0044238 primary metabolic process
1.49 1.08e-04 GO:0010628 positive regulation of gene expression
1.59 1.27e-04 GO:0072358 cardiovascular system development
1.59 1.27e-04 GO:0072359 circulatory system development
1.51 1.29e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.56 1.54e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.72 1.88e-04 GO:0060284 regulation of cell development
1.24 2.11e-04 GO:0048519 negative regulation of biological process
1.12 2.22e-04 GO:0008152 metabolic process
1.63 3.06e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.40 3.13e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.43 3.23e-04 GO:0051128 regulation of cellular component organization
1.27 3.47e-04 GO:0048583 regulation of response to stimulus
1.55 4.30e-04 GO:0048585 negative regulation of response to stimulus
1.40 4.61e-04 GO:0031324 negative regulation of cellular metabolic process
1.67 5.03e-04 GO:0045597 positive regulation of cell differentiation
1.44 5.04e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.17 5.24e-04 GO:0019222 regulation of metabolic process
1.44 5.28e-04 GO:2000026 regulation of multicellular organismal development
2.22 5.99e-04 GO:0010720 positive regulation of cell development
1.19 8.72e-04 GO:0007165 signal transduction
1.36 8.73e-04 GO:0010646 regulation of cell communication
1.55 9.21e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.07 1.44e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.67 1.45e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.40 1.49e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.22 1.55e-03 GO:0044267 cellular protein metabolic process
2.05 1.89e-03 GO:0022604 regulation of cell morphogenesis
2.03 2.04e-03 GO:0006470 protein dephosphorylation
1.36 2.14e-03 GO:0009892 negative regulation of metabolic process
1.38 2.44e-03 GO:0006351 transcription, DNA-dependent
1.54 2.59e-03 GO:0051094 positive regulation of developmental process
1.38 3.34e-03 GO:0009891 positive regulation of biosynthetic process
1.15 4.68e-03 GO:0051716 cellular response to stimulus
1.16 5.69e-03 GO:0023052 signaling
2.33 6.07e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.92 7.86e-03 GO:0016311 dephosphorylation
2.13 7.88e-03 GO:0030198 extracellular matrix organization
1.69 1.07e-02 GO:0050767 regulation of neurogenesis
1.31 1.19e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.40 1.41e-02 GO:0009790 embryo development
1.38 1.54e-02 GO:0006468 protein phosphorylation
1.29 1.99e-02 GO:0031325 positive regulation of cellular metabolic process
1.51 2.10e-02 GO:0016477 cell migration
1.85 2.43e-02 GO:0043062 extracellular structure organization
1.35 2.57e-02 GO:0016310 phosphorylation
1.43 2.80e-02 GO:0006928 cellular component movement
1.73 2.80e-02 GO:0045664 regulation of neuron differentiation
1.42 2.91e-02 GO:0009887 organ morphogenesis
1.63 3.06e-02 GO:0001568 blood vessel development
1.47 3.14e-02 GO:0048870 cell motility
1.47 3.14e-02 GO:0051674 localization of cell
1.69 3.74e-02 GO:0048514 blood vessel morphogenesis
1.60 4.10e-02 GO:0001944 vasculature development
1.26 4.84e-02 GO:0035556 intracellular signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 2.49e-16 GO:0044424 intracellular part
1.23 3.72e-16 GO:0005634 nucleus
1.10 9.94e-15 GO:0005622 intracellular
1.13 2.95e-14 GO:0043226 organelle
1.14 4.15e-14 GO:0043227 membrane-bounded organelle
1.13 4.31e-14 GO:0043229 intracellular organelle
1.14 6.51e-14 GO:0043231 intracellular membrane-bounded organelle
1.34 8.77e-09 GO:0031981 nuclear lumen
1.31 9.55e-09 GO:0044428 nuclear part
1.36 1.58e-06 GO:0005654 nucleoplasm
1.11 1.98e-06 GO:0005737 cytoplasm
1.26 7.78e-06 GO:0070013 intracellular organelle lumen
1.25 1.26e-05 GO:0043233 organelle lumen
1.24 2.43e-05 GO:0031974 membrane-enclosed lumen
1.42 2.27e-04 GO:0044451 nucleoplasm part
1.13 3.92e-04 GO:0044446 intracellular organelle part
1.04 6.69e-04 GO:0044464 cell part
1.04 7.04e-04 GO:0005623 cell
1.12 1.73e-03 GO:0044422 organelle part
1.80 8.72e-03 GO:0005912 adherens junction
1.99 1.03e-02 GO:0005925 focal adhesion
1.71 1.17e-02 GO:0031252 cell leading edge
1.95 1.38e-02 GO:0005924 cell-substrate adherens junction
1.93 1.44e-02 GO:0030055 cell-substrate junction
1.19 2.98e-02 GO:0005829 cytosol
1.44 3.83e-02 GO:0043005 neuron projection
1.56 4.08e-02 GO:0005667 transcription factor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.50e-14 GO:0005515 protein binding
1.09 2.18e-11 GO:0005488 binding
1.47 1.73e-08 GO:0030528 transcription regulator activity
1.72 3.26e-05 GO:0016564 transcription repressor activity
1.80 4.82e-05 GO:0016791 phosphatase activity
1.71 8.72e-05 GO:0008134 transcription factor binding
1.93 3.10e-04 GO:0004721 phosphoprotein phosphatase activity
1.62 3.51e-04 GO:0042578 phosphoric ester hydrolase activity
1.34 9.01e-04 GO:0001071 nucleic acid binding transcription factor activity
1.34 9.01e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
4.93 2.01e-03 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
1.40 2.97e-03 GO:0043565 sequence-specific DNA binding
1.20 3.43e-03 GO:0003677 DNA binding
1.49 4.01e-03 GO:0019904 protein domain specific binding
1.37 6.57e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.17 6.94e-03 GO:0019199 transmembrane receptor protein kinase activity
2.56 1.31e-02 GO:0046332 SMAD binding
1.68 1.41e-02 GO:0000975 regulatory region DNA binding
1.68 1.41e-02 GO:0001067 regulatory region nucleic acid binding
1.68 1.41e-02 GO:0044212 transcription regulatory region DNA binding
1.70 1.49e-02 GO:0010843 promoter binding
1.35 1.67e-02 GO:0019899 enzyme binding
1.48 2.59e-02 GO:0000988 protein binding transcription factor activity
1.48 2.59e-02 GO:0000989 transcription factor binding transcription factor activity
1.32 3.33e-02 GO:0016301 kinase activity
1.37 3.73e-02 GO:0004672 protein kinase activity
1.47 3.91e-02 GO:0003712 transcription cofactor activity
1.18 4.63e-02 GO:0000166 nucleotide binding