Motif ID: BACH2.p2

Z-value: 1.044


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BACH2chr6_-_910631810.273.0e-01Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_19706979 3.561 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr1_-_207891264 2.711 NM_001017402
LAMB3
laminin, beta 3
chr17_-_36996611 2.486 NM_000526
KRT14
keratin 14
chr19_+_43486640 2.270 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr11_+_384238 2.048 PKP3
plakophilin 3
chr5_-_141041982 2.044 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr5_-_141041933 1.959 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr3_-_197549640 1.892 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr1_-_108032645 1.757 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr3_-_48607596 1.740 NM_000094
COL7A1
collagen, type VII, alpha 1
chr11_+_384199 1.691 NM_007183
PKP3
plakophilin 3
chr2_+_113591940 1.688 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr17_-_37022465 1.680 NM_005557
KRT16
keratin 16
chr1_+_181421984 1.618 LAMC2
laminin, gamma 2
chr3_-_197549588 1.577 TM4SF19
transmembrane 4 L six family member 19
chr11_-_117640166 1.564 MPZL2
myelin protein zero-like 2
chr2_-_85494639 1.511 CAPG
capping protein (actin filament), gelsolin-like
chr11_-_2907169 1.466 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr12_-_51629874 1.459 KRT8
keratin 8
chr11_-_119499188 1.443 TRIM29
tripartite motif containing 29
chr11_-_117640078 1.387


chr11_-_117640196 1.370 MPZL2
myelin protein zero-like 2
chr3_-_152517204 1.310 NM_023915
GPR87
G protein-coupled receptor 87
chr19_-_48661563 1.305 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr11_-_117640407 1.275 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr19_+_7859380 1.243 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr1_-_6474346 1.232 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_+_116099648 1.215 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr17_+_71229110 1.204 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr6_+_41712907 1.197 MDFI
MyoD family inhibitor
chr3_+_11153778 1.181 NM_001098213
HRH1
histamine receptor H1
chr6_+_31190505 1.178 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr18_+_54039818 1.149 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr17_+_71229151 1.138 ITGB4
integrin, beta 4
chr19_-_43955984 1.136 NM_002307
LGALS7
LGALS7B
lectin, galactoside-binding, soluble, 7
lectin, galactoside-binding, soluble, 7B
chr18_+_59295123 1.122 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr18_+_50646616 1.105 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr1_-_150276114 1.087 NM_005620
S100A11
S100 calcium binding protein A11
chr18_+_54039779 1.087 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_181422016 1.086 LAMC2
laminin, gamma 2
chr9_+_102231616 1.060 NM_001198806
C9orf30
chromosome 9 open reading frame 30
chr5_+_145297490 1.052 SH3RF2
SH3 domain containing ring finger 2
chr6_-_84197370 1.044 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr3_-_12775718 1.043 NM_018306
TMEM40
transmembrane protein 40
chr8_+_22900863 1.030 NM_001160036
RHOBTB2
Rho-related BTB domain containing 2
chr12_-_15005761 1.014 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr18_+_54039730 0.997 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_891739 0.995 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr6_-_84197463 0.978 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_+_221966951 0.973 CAPN2
calpain 2, (m/II) large subunit
chr6_-_84197477 0.970 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr8_+_120289735 0.969 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr10_-_21503025 0.951 NM_001173484
NM_213569
NEBL

nebulette

chr19_+_43971689 0.944 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr6_-_84197573 0.939 NM_002395
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr10_-_21502993 0.932 NEBL
nebulette
chr17_+_71229191 0.926 ITGB4
integrin, beta 4
chr8_-_144887876 0.903 NM_198488
FAM83H
family with sequence similarity 83, member H
chr11_+_67107641 0.895 NM_000852
GSTP1
glutathione S-transferase pi 1
chr6_+_74462630 0.892 CD109
CD109 molecule
chr6_+_74462485 0.889 CD109
CD109 molecule
chr9_+_676640 0.887


chr19_-_56215084 0.886 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr1_+_181421796 0.877 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr6_+_74462654 0.869 CD109
CD109 molecule
chr10_+_70745615 0.863 NM_033496
HK1
hexokinase 1
chr11_+_67107852 0.855 GSTP1
glutathione S-transferase pi 1
chr6_+_47774247 0.843 NM_153838
GPR115
G protein-coupled receptor 115
chr6_+_74462577 0.837 CD109
CD109 molecule
chr15_-_58477407 0.831 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr1_+_27062215 0.810 NM_006142
SFN
stratifin
chr4_+_88076418 0.809


chr1_-_6585268 0.804 KLHL21
kelch-like 21 (Drosophila)
chr6_+_74462226 0.798 NM_001159587
NM_001159588
NM_133493
CD109


CD109 molecule


chr6_+_1556543 0.795 FOXC1
forkhead box C1
chr12_-_46439127 0.790 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_-_85494664 0.783 CAPG
capping protein (actin filament), gelsolin-like
chr1_+_154351082 0.780 NM_005572
NM_170707
NM_170708
LMNA


lamin A/C


chrX_+_30143595 0.760 NM_002364
MAGEB2
melanoma antigen family B, 2
chr1_+_154351162 0.754 LMNA
lamin A/C
chr1_-_156923111 0.741 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_+_161877640 0.738 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr17_+_72827227 0.735 SEPT9
septin 9
chr9_+_131291144 0.734


chrX_-_15421279 0.710 NM_001018109
NM_003662
PIR

pirin (iron-binding nuclear protein)

chr8_-_68821131 0.707 NM_020361
CPA6
carboxypeptidase A6
chr20_-_1257782 0.707 SDCBP2
syndecan binding protein (syntenin) 2
chr11_-_65424434 0.699 FOSL1
FOS-like antigen 1
chr12_-_46438447 0.694 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chrX_-_129072152 0.693 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chr11_-_65424385 0.692 FOSL1
FOS-like antigen 1
chr11_+_1812115 0.675 NM_138567
SYT8
synaptotagmin VIII
chr1_-_27212035 0.658 FAM46B
family with sequence similarity 46, member B
chr20_-_1257809 0.657 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr4_+_108965167 0.646 NM_001136258
SGMS2
sphingomyelin synthase 2
chr7_-_107430566 0.637 NM_002291
LAMB1
laminin, beta 1
chr17_+_72827185 0.635 NM_006640
SEPT9
septin 9
chr12_-_37585602 0.631 NM_153634
CPNE8
copine VIII
chr4_-_89299034 0.630 NM_004827
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr4_+_74825138 0.615 NM_000584
IL8
interleukin 8
chr11_-_66898223 0.615 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chrX_-_129072103 0.614 ELF4
E74-like factor 4 (ets domain transcription factor)
chrX_-_15198093 0.605 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr1_+_221966835 0.605 CAPN2
calpain 2, (m/II) large subunit
chr9_+_131291224 0.599 LOC100506190
hypothetical LOC100506190
chrX_-_129072333 0.590 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr1_-_1679940 0.585 NM_001198995
NADK
NAD kinase
chr1_+_221966684 0.585 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr1_+_221966849 0.580 CAPN2
calpain 2, (m/II) large subunit
chr14_+_104218487 0.579


chr17_-_7064092 0.578 NM_001365
DLG4
discs, large homolog 4 (Drosophila)
chr1_+_151270301 0.572 NM_003125
SPRR1B
small proline-rich protein 1B
chr4_+_152549776 0.566 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr19_-_48977247 0.564 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_-_65424436 0.564 NM_005438
FOSL1
FOS-like antigen 1
chr19_-_48866111 0.558 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr6_+_32229278 0.549 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr1_-_28392966 0.548 NM_001164722
NM_001164721
PTAFR

platelet-activating factor receptor

chr15_+_38849450 0.545 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr10_-_6059460 0.543 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr18_+_59405513 0.534 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr19_-_48976852 0.530 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_-_74307637 0.529 ANKRD17
ankyrin repeat domain 17
chr15_+_99276982 0.526 NM_024652
LRRK1
leucine-rich repeat kinase 1
chr1_-_154941861 0.524 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr1_-_94779727 0.523 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr12_-_56445653 0.522 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr20_+_43468617 0.521 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr17_+_71893014 0.516 SPHK1
sphingosine kinase 1
chr6_-_150388292 0.508 NM_130900
RAET1L
retinoic acid early transcript 1L
chr13_-_40491405 0.506 ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_-_65860450 0.503 NM_004292
RIN1
Ras and Rab interactor 1
chr7_-_1465487 0.500 MICALL2
MICAL-like 2
chr11_-_128399218 0.498 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_-_209915443 0.488 NM_002497
NEK2
NIMA (never in mitosis gene a)-related kinase 2
chr12_-_51153788 0.480 NM_173086
KRT6C
keratin 6C
chr2_+_47449790 0.476 NM_002354
EPCAM
epithelial cell adhesion molecule
chr20_-_17487480 0.476 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr11_-_6298284 0.472 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr16_-_2848106 0.470 NM_022119
PRSS22
protease, serine, 22
chr16_+_56219802 0.466 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr18_-_45630154 0.461 MYO5B
myosin VB
chr17_+_71892538 0.458 SPHK1
sphingosine kinase 1
chr17_+_71892781 0.452 NM_001142602
SPHK1
sphingosine kinase 1
chr1_+_154351200 0.451 LMNA
lamin A/C
chr1_-_27211913 0.451 NM_052943
FAM46B
family with sequence similarity 46, member B
chr11_+_10433241 0.451 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr4_-_177950658 0.446 NM_005429
VEGFC
vascular endothelial growth factor C
chr12_+_55018925 0.440 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr13_-_40491491 0.438 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_220200530 0.437 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr17_+_7063970 0.433 ACADVL
acyl-CoA dehydrogenase, very long chain
chr16_-_1369613 0.428 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr17_+_18566060 0.420 NM_001037330
TRIM16L
tripartite motif containing 16-like
chr1_-_6585485 0.417 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr3_+_11242666 0.417 NM_001098211
HRH1
histamine receptor H1
chr6_-_150001376 0.412 NM_007044
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr17_+_22823151 0.410 NM_014238
KSR1
kinase suppressor of ras 1
chr6_+_44302973 0.409 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr6_-_138470160 0.405 NM_022121
PERP
PERP, TP53 apoptosis effector
chr10_-_73281056 0.397 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr18_+_59593591 0.394 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_148747208 0.392 ECM1
extracellular matrix protein 1
chr2_+_47449951 0.389 EPCAM
epithelial cell adhesion molecule
chr10_-_88720908 0.385 LOC100133190
hypothetical LOC100133190
chr22_-_35914200 0.384 NM_031910
NM_182486
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr1_-_151788341 0.381 NM_002960
S100A3
S100 calcium binding protein A3
chr1_+_152644292 0.380 NM_000565
NM_181359
IL6R

interleukin 6 receptor

chr17_+_7063873 0.377 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr4_+_159351092 0.376 TMEM144
transmembrane protein 144
chr10_-_73281047 0.376 PSAP
prosaposin
chr21_-_35181956 0.375 RUNX1
runt-related transcription factor 1
chr17_-_3407780 0.375 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr5_+_40877053 0.375 NM_032587
CARD6
caspase recruitment domain family, member 6
chr17_-_39700960 0.373 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr6_-_31853027 0.371 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr3_+_175641340 0.371 NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr22_+_19191884 0.370 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr1_-_205290921 0.369 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr16_-_62573 0.368 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_-_177378801 0.367 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr1_+_17719405 0.363 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_152644668 0.360 IL6R
interleukin 6 receptor
chr1_-_150276091 0.360 S100A11
S100 calcium binding protein A11
chr6_-_28429950 0.360 NM_145909
ZNF323
zinc finger protein 323
chr22_+_19191875 0.358 MED15
mediator complex subunit 15
chr9_-_124030770 0.355 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr8_+_144888275 0.355 LOC100128338
hypothetical LOC100128338
chr22_+_19191886 0.354 MED15
mediator complex subunit 15
chr10_-_73280964 0.352 PSAP
prosaposin
chr17_-_36792161 0.351 NM_021013
KRT34
keratin 34
chr2_+_201830998 0.350 NM_001080125
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr8_-_127639647 0.350 FAM84B
family with sequence similarity 84, member B
chr22_+_19191898 0.346 MED15
mediator complex subunit 15
chr22_+_19191964 0.346 MED15
mediator complex subunit 15
chr1_-_221920023 0.345 NM_001143962
CAPN8
calpain 8
chr16_+_82544327 0.344 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr1_+_148747110 0.344 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr4_-_100575313 0.344 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr1_+_35019376 0.340 NM_024009
GJB3
gap junction protein, beta 3, 31kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.43 1.67e-03 GO:0007264 small GTPase mediated signal transduction

Nothing significant found in compartment category.

Nothing significant found in function category.