Motif ID: POU5F1.p2

Z-value: 1.660


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_31246159-0.712.3e-03Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_76667045 3.765 NM_006682
 FGL2
fibrinogen-like 2
chr1_-_153098811 3.327 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr10_-_98021144 3.170 NM_001114094
NM_013314
 BLNK

B-cell linker

chr5_-_124108672 2.848 NM_020747
 ZNF608
zinc finger protein 608
chr10_+_11246934 2.433 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr5_-_88155360 2.413 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr4_-_91979113 2.352 NM_183049
 TMSL3
thymosin-like 3
chr22_-_44828636 2.178 NM_018280
 C22orf26
chromosome 22 open reading frame 26
chr19_-_43800374 2.152 NM_001042600
NM_007181
 MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr1_+_165565006 2.019 POU2F1
POU class 2 homeobox 1
chr5_-_111119846 1.961 NM_001142483
 C5orf13
chromosome 5 open reading frame 13
chr12_-_16649211 1.904 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_197173159 1.880 LOC100131234
familial acute myelogenous leukemia related factor
chr12_+_14409875 1.827 NM_018179
 ATF7IP
activating transcription factor 7 interacting protein
chr3_+_179736917 1.809 NM_181361
 KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_-_93512818 1.793 ASB2
ankyrin repeat and SOCS box containing 2
chr6_-_42527760 1.769 NM_033502
 TRERF1
transcriptional regulating factor 1
chr3_+_99733432 1.737 NM_005290
 GPR15
G protein-coupled receptor 15
chr1_+_165564904 1.737 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr15_-_78050515 1.729 NM_001114735
NM_004049
 BCL2A1

BCL2-related protein A1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
1.68 2.06e-02 GO:0001775 cell activation
1.66 3.27e-02 GO:0007417 central nervous system development
1.63 1.07e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.61 8.44e-03 GO:0010628 positive regulation of gene expression
1.58 1.62e-02 GO:0030182 neuron differentiation
1.55 1.74e-02 GO:0006955 immune response
1.54 7.89e-07 GO:0007399 nervous system development
1.53 2.32e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.53 4.11e-03 GO:0022008 neurogenesis
1.52 1.59e-02 GO:0048699 generation of neurons
1.48 8.10e-04 GO:0002376 immune system process
1.45 5.21e-06 GO:0048513 organ development
1.44 4.19e-10 GO:0048731 system development
1.41 1.82e-04 GO:0007166 cell surface receptor linked signaling pathway
1.40 6.94e-06 GO:0051252 regulation of RNA metabolic process
1.40 9.68e-06 GO:0006355 regulation of transcription, DNA-dependent
1.39 4.34e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 9.43e-09 GO:0048856 anatomical structure development
1.37 8.50e-06 GO:0010468 regulation of gene expression
1.36 2.68e-05 GO:0010556 regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.24 2.21e-08 GO:0005634 nucleus
1.17 2.16e-02 GO:0005886 plasma membrane
1.17 3.16e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
3.47 2.83e-02 GO:0003823 antigen binding
2.78 1.93e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.92 6.64e-04 GO:0003779 actin binding
1.61 3.88e-06 GO:0001071 nucleic acid binding transcription factor activity
1.61 3.88e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.60 1.39e-03 GO:0043565 sequence-specific DNA binding
1.56 4.10e-05 GO:0030528 transcription regulator activity
1.38 2.26e-06 GO:0003677 DNA binding
1.26 2.75e-04 GO:0003676 nucleic acid binding
1.13 3.60e-03 GO:0005515 protein binding
1.07 3.81e-03 GO:0005488 binding