Motif ID: POU5F1.p2

Z-value: 1.660


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_31246159-0.712.3e-03Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_76667045 3.765 NM_006682
FGL2
fibrinogen-like 2
chr1_-_153098811 3.327 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr10_-_98021144 3.170 NM_001114094
NM_013314
BLNK

B-cell linker

chr5_-_124108672 2.848 NM_020747
ZNF608
zinc finger protein 608
chr10_+_11246934 2.433 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr5_-_88155360 2.413 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr4_-_91979113 2.352 NM_183049
TMSL3
thymosin-like 3
chr22_-_44828636 2.178 NM_018280
C22orf26
chromosome 22 open reading frame 26
chr19_-_43800374 2.152 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr1_+_165565006 2.019 POU2F1
POU class 2 homeobox 1
chr5_-_111119846 1.961 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr12_-_16649211 1.904 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_197173159 1.880 LOC100131234
familial acute myelogenous leukemia related factor
chr12_+_14409875 1.827 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr3_+_179736917 1.809 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_-_93512818 1.793 ASB2
ankyrin repeat and SOCS box containing 2
chr6_-_42527760 1.769 NM_033502
TRERF1
transcriptional regulating factor 1
chr3_+_99733432 1.737 NM_005290
GPR15
G protein-coupled receptor 15
chr1_+_165564904 1.737 NM_001198783
POU2F1
POU class 2 homeobox 1
chr15_-_78050515 1.729 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr6_-_26151863 1.692 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chrX_-_62891066 1.686 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_+_242281175 1.669 NM_205768
ZNF238
zinc finger protein 238
chr17_-_59363352 1.653 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr2_+_68815416 1.651 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr3_-_64186151 1.651 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_+_33494745 1.639 NM_152493
ZNF362
zinc finger protein 362
chr5_+_140871107 1.580


chr3_-_129023850 1.578 NM_007283
MGLL
monoglyceride lipase
chr5_-_88215034 1.528 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_+_242281199 1.499 ZNF238
zinc finger protein 238
chr19_+_14554895 1.488 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr1_-_205012348 1.486 NM_000572
IL10
interleukin 10
chr14_-_93512647 1.461 ASB2
ankyrin repeat and SOCS box containing 2
chr6_+_21701942 1.450 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr12_+_111829121 1.420 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr12_-_16650697 1.405 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_33016561 1.394 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_+_88966170 1.389


chr5_-_176868483 1.388 DOK3
docking protein 3
chr8_+_11388918 1.294 NM_001715
BLK
B lymphoid tyrosine kinase
chr16_+_10878539 1.292 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chrX_-_106846684 1.283 TSC22D3
TSC22 domain family, member 3
chr12_-_48902692 1.248 NM_001113547
LIMA1
LIM domain and actin binding 1
chr1_-_158948176 1.248 NM_001778
CD48
CD48 molecule
chr1_-_108308997 1.228 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr7_+_128795280 1.191 AHCYL2
adenosylhomocysteinase-like 2
chrX_+_12903145 1.178 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr6_-_32665409 1.172 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr8_-_72431274 1.172 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr12_+_91620749 1.171 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr3_-_16530132 1.171 NM_015150
RFTN1
raftlin, lipid raft linker 1
chrX_-_106846924 1.144 NM_004089
TSC22D3
TSC22 domain family, member 3
chr1_+_100957883 1.144 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr1_-_31003181 1.138 LAPTM5
lysosomal protein transmembrane 5
chr21_-_35343065 1.129 RUNX1
runt-related transcription factor 1
chr1_+_208008517 1.120 TRAF3IP3
TRAF3 interacting protein 3
chr1_-_31003260 1.119 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr19_-_1083109 1.111 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr10_+_11247059 1.108 CELF2
CUGBP, Elav-like family member 2
chr3_+_135996990 1.104 EPHB1
EPH receptor B1
chr5_+_140870881 1.099


chr4_-_110443247 1.098 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr6_+_167456230 1.089 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr1_-_42738535 1.081 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr3_+_135996734 1.069 NM_004441
EPHB1
EPH receptor B1
chr9_+_94766379 1.065 FGD3
FYVE, RhoGEF and PH domain containing 3
chr19_+_40511909 1.055 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chrX_-_33267646 1.052 NM_000109
DMD
dystrophin
chr13_+_110637173 1.050 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_153493133 1.042 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr5_+_49998677 1.041 PARP8
poly (ADP-ribose) polymerase family, member 8
chr4_-_113656762 1.040 NM_024019
NEUROG2
neurogenin 2
chrX_-_80344096 1.033 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chr3_-_113334657 1.028 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr18_+_40514772 1.017 NM_015559
SETBP1
SET binding protein 1
chr1_+_145479805 1.010 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr17_-_16816113 1.009 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr12_-_101115677 0.998 NM_002674
PMCH
pro-melanin-concentrating hormone
chr5_+_49998528 0.992 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr18_-_59137488 0.988 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr7_+_128795178 0.985 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr10_+_91051685 0.965 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr1_-_23758503 0.949 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_-_207738858 0.947 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_+_5750229 0.943 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr17_-_8756524 0.936 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr2_+_68445821 0.923 NM_002664
PLEK
pleckstrin
chr7_+_18501876 0.919 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr3_-_52235218 0.918 NM_017442
TLR9
toll-like receptor 9
chr11_+_5610060 0.915 NM_130390
TRIM34
tripartite motif containing 34
chr11_+_46339691 0.913 NM_001105540
DGKZ
diacylglycerol kinase, zeta
chr12_-_16650687 0.911 LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_3049872 0.909 NM_032415
CARD11
caspase recruitment domain family, member 11
chr4_+_81325447 0.905 NM_020226
PRDM8
PR domain containing 8
chr2_+_237143118 0.897 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr22_+_20715340 0.888


chr3_+_129124591 0.886 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_+_161305558 0.878 NM_001113381
RGS4
regulator of G-protein signaling 4
chr1_+_190552744 0.864 NM_001039152
RGS21
regulator of G-protein signaling 21
chr2_+_170742900 0.864 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr11_+_128068982 0.861 NM_002017
FLI1
Friend leukemia virus integration 1
chr1_+_66570683 0.861 PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_+_189547358 0.857 COL3A1
collagen, type III, alpha 1
chrX_-_77469635 0.856 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr5_-_36337756 0.847 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr8_+_123863075 0.847 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr18_+_40513889 0.845 NM_001130110
SETBP1
SET binding protein 1
chr7_+_45033757 0.844 NM_001029835
CCM2
cerebral cavernous malformation 2
chr5_-_111120764 0.839 C5orf13
chromosome 5 open reading frame 13
chrX_+_80344253 0.839 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr14_-_105804211 0.837 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_+_123863169 0.836 ZHX2
zinc fingers and homeoboxes 2
chr3_-_16529996 0.830 RFTN1
raftlin, lipid raft linker 1
chr9_-_35608300 0.828 NM_001782
CD72
CD72 molecule
chr7_-_129868059 0.821 NM_018718
TSGA14
testis specific, 14
chr10_+_68355797 0.818 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr12_+_111829191 0.817 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr11_+_128069203 0.814 FLI1
Friend leukemia virus integration 1
chr17_-_39094787 0.810 NM_001040002
MEOX1
mesenchyme homeobox 1
chr11_+_128069183 0.801 FLI1
Friend leukemia virus integration 1
chr3_+_29297806 0.799 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr11_+_128069165 0.799 FLI1
Friend leukemia virus integration 1
chrX_-_77801480 0.798 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr6_-_56824672 0.797 DST
dystonin
chr11_-_26700121 0.797 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr6_+_26381122 0.796 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr13_-_98757634 0.794 NM_004951
GPR183
G protein-coupled receptor 183
chr10_+_11247243 0.787 CELF2
CUGBP, Elav-like family member 2
chr4_-_38460983 0.775 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr4_+_113958652 0.773 NM_001127493
ANK2
ankyrin 2, neuronal
chr22_+_21370394 0.772 IGL@
immunoglobulin lambda locus
chr2_+_189547377 0.771 COL3A1
collagen, type III, alpha 1
chr9_+_18464138 0.769 ADAMTSL1
ADAMTS-like 1
chr21_+_25933938 0.766 JAM2
junctional adhesion molecule 2
chr8_+_123863224 0.766 ZHX2
zinc fingers and homeoboxes 2
chr2_+_108751033 0.762 RANBP2
RAN binding protein 2
chr5_-_111120817 0.755 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr4_-_164754106 0.754 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr8_+_70567634 0.752 SULF1
sulfatase 1
chr1_+_190811479 0.750 NM_002922
RGS1
regulator of G-protein signaling 1
chr8_+_86287161 0.746 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr21_+_25933916 0.743 JAM2
junctional adhesion molecule 2
chr2_-_225519974 0.740 DOCK10
dedicator of cytokinesis 10
chr10_+_63331401 0.737 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_-_32892705 0.733 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr6_-_25044156 0.730 FAM65B
family with sequence similarity 65, member B
chrX_-_135690699 0.728 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_179719338 0.727 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_66570363 0.726 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr22_-_34886727 0.724 NM_145640
APOL3
apolipoprotein L, 3
chr17_+_64922420 0.720 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chrX_-_33139349 0.718 NM_004006
DMD
dystrophin
chrX_+_80344215 0.718 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr9_+_112470871 0.718 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr6_-_149847809 0.717 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chrX_+_154264931 0.716 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr19_-_53444733 0.713 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr3_-_58175437 0.711 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr15_-_50608296 0.709 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr11_+_128069340 0.703 FLI1
Friend leukemia virus integration 1
chr6_-_149847718 0.698 ZC3H12D
zinc finger CCCH-type containing 12D
chr1_-_42156957 0.690 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr22_+_30072739 0.686 FLJ20464
hypothetical protein FLJ20464
chr6_-_56824371 0.684 DST
dystonin
chr1_-_28376041 0.683 NM_000952
PTAFR
platelet-activating factor receptor
chr1_-_111544603 0.681


chr22_-_36212160 0.679 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr3_+_142587973 0.677


chr5_-_54317102 0.675 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_-_171442937 0.674 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chrX_-_135690770 0.673 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr16_+_31274020 0.670 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr14_-_105623358 0.669 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_83052606 0.668 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr8_+_70567581 0.653 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr5_+_49997489 0.648 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_+_73826244 0.648 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr2_-_213723298 0.648 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_+_65027721 0.647


chr1_-_42157077 0.647 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr7_+_99654806 0.644 NM_024070
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr14_-_106241445 0.644 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr7_+_149842850 0.644 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr3_-_102194938 0.643 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr7_-_44088561 0.640 POLM
polymerase (DNA directed), mu
chr5_-_140875591 0.634 DIAPH1
diaphanous homolog 1 (Drosophila)
chr6_-_170442090 0.631


chr16_+_31274030 0.626 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr8_-_119703297 0.623 SAMD12
sterile alpha motif domain containing 12
chr2_+_189547323 0.620 NM_000090
COL3A1
collagen, type III, alpha 1
chr11_-_47356479 0.619 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr15_-_40537002 0.617 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr15_-_38387357 0.617 PLCB2
phospholipase C, beta 2
chr6_+_44295219 0.617 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr5_+_155686333 0.616 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr12_-_8656705 0.614 NM_020661
AICDA
activation-induced cytidine deaminase
chr7_-_27186400 0.613 NM_153715
HOXA10
homeobox A10
chr5_+_132037271 0.608 NM_000589
NM_172348
IL4

interleukin 4

chr19_+_57531309 0.602 NM_001161425
NM_001161426
NM_001161427
ZNF610


zinc finger protein 610



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.24 7.70e-12 GO:0050794 regulation of cellular process
1.22 1.99e-10 GO:0050789 regulation of biological process
1.44 4.19e-10 GO:0048731 system development
1.20 8.01e-10 GO:0065007 biological regulation
1.38 9.43e-09 GO:0048856 anatomical structure development
1.27 1.68e-08 GO:0032501 multicellular organismal process
1.35 6.77e-08 GO:0007275 multicellular organismal development
1.32 1.62e-07 GO:0032502 developmental process
1.54 7.89e-07 GO:0007399 nervous system development
1.21 2.21e-06 GO:0050896 response to stimulus
1.39 4.34e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.45 5.21e-06 GO:0048513 organ development
1.40 6.94e-06 GO:0051252 regulation of RNA metabolic process
1.37 8.50e-06 GO:0010468 regulation of gene expression
1.40 9.68e-06 GO:0006355 regulation of transcription, DNA-dependent
1.36 2.68e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.33 8.99e-05 GO:0031326 regulation of cellular biosynthetic process
1.33 1.25e-04 GO:0009889 regulation of biosynthetic process
1.26 1.71e-04 GO:0023052 signaling
1.41 1.82e-04 GO:0007166 cell surface receptor linked signaling pathway
1.27 4.32e-04 GO:0060255 regulation of macromolecule metabolic process
1.26 4.55e-04 GO:0031323 regulation of cellular metabolic process
1.27 5.85e-04 GO:0007165 signal transduction
1.31 6.09e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 7.53e-04 GO:0080090 regulation of primary metabolic process
1.48 8.10e-04 GO:0002376 immune system process
1.30 1.11e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.23 2.01e-03 GO:0019222 regulation of metabolic process
1.53 2.32e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.29 2.81e-03 GO:0048518 positive regulation of biological process
1.53 4.11e-03 GO:0022008 neurogenesis
1.33 5.22e-03 GO:0030154 cell differentiation
1.21 5.34e-03 GO:0051716 cellular response to stimulus
1.61 8.44e-03 GO:0010628 positive regulation of gene expression
1.32 9.25e-03 GO:0048869 cellular developmental process
1.63 1.07e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.52 1.59e-02 GO:0048699 generation of neurons
1.58 1.62e-02 GO:0030182 neuron differentiation
1.55 1.74e-02 GO:0006955 immune response
1.68 2.06e-02 GO:0001775 cell activation
1.28 2.19e-02 GO:0048522 positive regulation of cellular process
1.66 3.27e-02 GO:0007417 central nervous system development
1.08 3.37e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 2.21e-08 GO:0005634 nucleus
1.17 2.16e-02 GO:0005886 plasma membrane
1.17 3.16e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.38 2.26e-06 GO:0003677 DNA binding
1.61 3.88e-06 GO:0001071 nucleic acid binding transcription factor activity
1.61 3.88e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.56 4.10e-05 GO:0030528 transcription regulator activity
1.26 2.75e-04 GO:0003676 nucleic acid binding
1.92 6.64e-04 GO:0003779 actin binding
1.60 1.39e-03 GO:0043565 sequence-specific DNA binding
1.13 3.60e-03 GO:0005515 protein binding
1.07 3.81e-03 GO:0005488 binding
2.78 1.93e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
3.47 2.83e-02 GO:0003823 antigen binding