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Motif ID: POU5F1.p2

Z-value: 1.660

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_76667045	3.765	NM_006682	FGL2	fibrinogen-like 2
chr1_-_153098811	3.327	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr10_-_98021144	3.170	NM_001114094 NM_013314	BLNK	B-cell linker
chr5_-_124108672	2.848	NM_020747	ZNF608	zinc finger protein 608
chr10_+_11246934	2.433	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr5_-_88155360	2.413	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr4_-_91979113	2.352	NM_183049	TMSL3	thymosin-like 3
chr22_-_44828636	2.178	NM_018280	C22orf26	chromosome 22 open reading frame 26
chr19_-_43800374	2.152	NM_001042600 NM_007181	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr1_+_165565006	2.019		POU2F1	POU class 2 homeobox 1
chr5_-_111119846	1.961	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr12_-_16649211	1.904		LMO3	LIM domain only 3 (rhombotin-like 2)
chr1_-_197173159	1.880		LOC100131234	familial acute myelogenous leukemia related factor
chr12_+_14409875	1.827	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr3_+_179736917	1.809	NM_181361	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_-_93512818	1.793		ASB2	ankyrin repeat and SOCS box containing 2
chr6_-_42527760	1.769	NM_033502	TRERF1	transcriptional regulating factor 1
chr3_+_99733432	1.737	NM_005290	GPR15	G protein-coupled receptor 15
chr1_+_165564904	1.737	NM_001198783	POU2F1	POU class 2 homeobox 1
chr15_-_78050515	1.729	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr6_-_26151863	1.692	NM_021062	HIST1H2BB	histone cluster 1, H2bb
chrX_-_62891066	1.686		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_+_242281175	1.669	NM_205768	ZNF238	zinc finger protein 238
chr17_-_59363352	1.653	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr2_+_68815416	1.651	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr3_-_64186151	1.651	NM_198859	PRICKLE2	prickle homolog 2 (Drosophila)
chr1_+_33494745	1.639	NM_152493	ZNF362	zinc finger protein 362
chr5_+_140871107	1.580
chr3_-_129023850	1.578	NM_007283	MGLL	monoglyceride lipase
chr5_-_88215034	1.528	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr1_+_242281199	1.499		ZNF238	zinc finger protein 238
chr19_+_14554895	1.488	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr1_-_205012348	1.486	NM_000572	IL10	interleukin 10
chr14_-_93512647	1.461		ASB2	ankyrin repeat and SOCS box containing 2
chr6_+_21701942	1.450	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr12_+_111829121	1.420	NM_001032409 NM_002534 NM_016816	OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_16650697	1.405	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr6_-_33016561	1.394	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr2_+_88966170	1.389
chr5_-_176868483	1.388		DOK3	docking protein 3
chr8_+_11388918	1.294	NM_001715	BLK	B lymphoid tyrosine kinase
chr16_+_10878539	1.292	NM_000246	CIITA	class II, major histocompatibility complex, transactivator
chrX_-_106846684	1.283		TSC22D3	TSC22 domain family, member 3
chr12_-_48902692	1.248	NM_001113547	LIMA1	LIM domain and actin binding 1
chr1_-_158948176	1.248	NM_001778	CD48	CD48 molecule
chr1_-_108308997	1.228	NM_006113	VAV3	vav 3 guanine nucleotide exchange factor
chr7_+_128795280	1.191		AHCYL2	adenosylhomocysteinase-like 2
chrX_+_12903145	1.178	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr6_-_32665409	1.172	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr8_-_72431274	1.172	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr12_+_91620749	1.171	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr3_-_16530132	1.171	NM_015150	RFTN1	raftlin, lipid raft linker 1
chrX_-_106846924	1.144	NM_004089	TSC22D3	TSC22 domain family, member 3
chr1_+_100957883	1.144	NM_001078 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr1_-_31003181	1.138		LAPTM5	lysosomal protein transmembrane 5
chr21_-_35343065	1.129		RUNX1	runt-related transcription factor 1
chr1_+_208008517	1.120		TRAF3IP3	TRAF3 interacting protein 3
chr1_-_31003260	1.119	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr19_-_1083109	1.111	NM_001100122	SBNO2	strawberry notch homolog 2 (Drosophila)
chr10_+_11247059	1.108		CELF2	CUGBP, Elav-like family member 2
chr3_+_135996990	1.104		EPHB1	EPH receptor B1
chr5_+_140870881	1.099
chr4_-_110443247	1.098	NM_032518 NM_198721	COL25A1	collagen, type XXV, alpha 1
chr6_+_167456230	1.089	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr1_-_42738535	1.081		TMSB4XP1	thymosin beta 4, X-linked pseudogene 1
chr3_+_135996734	1.069	NM_004441	EPHB1	EPH receptor B1
chr9_+_94766379	1.065		FGD3	FYVE, RhoGEF and PH domain containing 3
chr19_+_40511909	1.055	NM_001185099 NM_001185100 NM_001185101 NM_001771	CD22	CD22 molecule
chrX_-_33267646	1.052	NM_000109	DMD	dystrophin
chr13_+_110637173	1.050	NM_001113513	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_153493133	1.042	NM_018315	FBXW7	F-box and WD repeat domain containing 7
chr5_+_49998677	1.041		PARP8	poly (ADP-ribose) polymerase family, member 8
chr4_-_113656762	1.040	NM_024019	NEUROG2	neurogenin 2
chrX_-_80344096	1.033	NM_030763	HMGN5	high-mobility group nucleosome binding domain 5
chr3_-_113334657	1.028	NM_001190259 NM_001190260 NM_152785	GCET2	germinal center expressed transcript 2
chr18_+_40514772	1.017	NM_015559	SETBP1	SET binding protein 1
chr1_+_145479805	1.010	NM_004326	BCL9	B-cell CLL/lymphoma 9
chr17_-_16816113	1.009	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr12_-_101115677	0.998	NM_002674	PMCH	pro-melanin-concentrating hormone
chr5_+_49998528	0.992	NM_001178056 NM_024615	PARP8	poly (ADP-ribose) polymerase family, member 8
chr18_-_59137488	0.988	NM_000633 NM_000657	BCL2	B-cell CLL/lymphoma 2
chr7_+_128795178	0.985	NM_001130723	AHCYL2	adenosylhomocysteinase-like 2
chr10_+_91051685	0.965	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chr1_-_23758503	0.949		ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_-_207738858	0.947	NM_003709	KLF7	Kruppel-like factor 7 (ubiquitous)
chr2_+_5750229	0.943	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr17_-_8756524	0.936	NM_014308	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5
chr2_+_68445821	0.923	NM_002664	PLEK	pleckstrin
chr7_+_18501876	0.919	NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr3_-_52235218	0.918	NM_017442	TLR9	toll-like receptor 9
chr11_+_5610060	0.915	NM_130390	TRIM34	tripartite motif containing 34
chr11_+_46339691	0.913	NM_001105540	DGKZ	diacylglycerol kinase, zeta
chr12_-_16650687	0.911		LMO3	LIM domain only 3 (rhombotin-like 2)
chr7_-_3049872	0.909	NM_032415	CARD11	caspase recruitment domain family, member 11
chr4_+_81325447	0.905	NM_020226	PRDM8	PR domain containing 8
chr2_+_237143118	0.897	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr22_+_20715340	0.888
chr3_+_129124591	0.886	NM_207335	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr1_+_161305558	0.878	NM_001113381	RGS4	regulator of G-protein signaling 4
chr1_+_190552744	0.864	NM_001039152	RGS21	regulator of G-protein signaling 21
chr2_+_170742900	0.864	NM_001083615 NM_001171642 NM_138995	MYO3B	myosin IIIB
chr11_+_128068982	0.861	NM_002017	FLI1	Friend leukemia virus integration 1
chr1_+_66570683	0.861		PDE4B	phosphodiesterase 4B, cAMP-specific
chr2_+_189547358	0.857		COL3A1	collagen, type III, alpha 1
chrX_-_77469635	0.856	NM_006639	CYSLTR1	cysteinyl leukotriene receptor 1
chr5_-_36337756	0.847	NM_001161429 NM_145000	RANBP3L	RAN binding protein 3-like
chr8_+_123863075	0.847	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr18_+_40513889	0.845	NM_001130110	SETBP1	SET binding protein 1
chr7_+_45033757	0.844	NM_001029835	CCM2	cerebral cavernous malformation 2
chr5_-_111120764	0.839		C5orf13	chromosome 5 open reading frame 13
chrX_+_80344253	0.839		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr14_-_105804211	0.837		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_+_123863169	0.836		ZHX2	zinc fingers and homeoboxes 2
chr3_-_16529996	0.830		RFTN1	raftlin, lipid raft linker 1
chr9_-_35608300	0.828	NM_001782	CD72	CD72 molecule
chr7_-_129868059	0.821	NM_018718	TSGA14	testis specific, 14
chr10_+_68355797	0.818	NM_178011	LRRTM3	leucine rich repeat transmembrane neuronal 3
chr12_+_111829191	0.817		OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chr11_+_128069203	0.814		FLI1	Friend leukemia virus integration 1
chr17_-_39094787	0.810	NM_001040002	MEOX1	mesenchyme homeobox 1
chr11_+_128069183	0.801		FLI1	Friend leukemia virus integration 1
chr3_+_29297806	0.799	NM_001003792 NM_001003793 NM_001177711 NM_001177712 NM_014483	RBMS3	RNA binding motif, single stranded interacting protein 3
chr11_+_128069165	0.799		FLI1	Friend leukemia virus integration 1
chrX_-_77801480	0.798	NM_152694	ZCCHC5	zinc finger, CCHC domain containing 5
chr6_-_56824672	0.797		DST	dystonin
chr11_-_26700121	0.797	NM_178498	SLC5A12	solute carrier family 5 (sodium/glucose cotransporter), member 12
chr6_+_26381122	0.796	NM_003525	HIST1H2BI	histone cluster 1, H2bi
chr13_-_98757634	0.794	NM_004951	GPR183	G protein-coupled receptor 183
chr10_+_11247243	0.787		CELF2	CUGBP, Elav-like family member 2
chr4_-_38460983	0.775	NM_001017388 NM_001195106 NM_001195107 NM_001195108 NM_030956	TLR10	toll-like receptor 10
chr4_+_113958652	0.773	NM_001127493	ANK2	ankyrin 2, neuronal
chr22_+_21370394	0.772		IGL@	immunoglobulin lambda locus
chr2_+_189547377	0.771		COL3A1	collagen, type III, alpha 1
chr9_+_18464138	0.769		ADAMTSL1	ADAMTS-like 1
chr21_+_25933938	0.766		JAM2	junctional adhesion molecule 2
chr8_+_123863224	0.766		ZHX2	zinc fingers and homeoboxes 2
chr2_+_108751033	0.762		RANBP2	RAN binding protein 2
chr5_-_111120817	0.755	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr4_-_164754106	0.754	NM_017923	MARCH1	membrane-associated ring finger (C3HC4) 1
chr8_+_70567634	0.752		SULF1	sulfatase 1
chr1_+_190811479	0.750	NM_002922	RGS1	regulator of G-protein signaling 1
chr8_+_86287161	0.746	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr21_+_25933916	0.743		JAM2	junctional adhesion molecule 2
chr2_-_225519974	0.740		DOCK10	dedicator of cytokinesis 10
chr10_+_63331401	0.737		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr6_-_32892705	0.733	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr6_-_25044156	0.730		FAM65B	family with sequence similarity 65, member B
chrX_-_135690699	0.728		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_179719338	0.727	NM_000721	CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_66570363	0.726	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr22_-_34886727	0.724	NM_145640	APOL3	apolipoprotein L, 3
chr17_+_64922420	0.720	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chrX_-_33139349	0.718	NM_004006	DMD	dystrophin
chrX_+_80344215	0.718		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr9_+_112470871	0.718	NM_001166280 NM_001166281 NM_005592	MUSK	muscle, skeletal, receptor tyrosine kinase
chr6_-_149847809	0.717	NM_207360	ZC3H12D	zinc finger CCCH-type containing 12D
chrX_+_154264931	0.716	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr19_-_53444733	0.713	NM_001184901 NM_001184903 NM_014959	CARD8	caspase recruitment domain family, member 8
chr3_-_58175437	0.711	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr15_-_50608296	0.709	NM_000259 NM_001142495	MYO5A	myosin VA (heavy chain 12, myoxin)
chr11_+_128069340	0.703		FLI1	Friend leukemia virus integration 1
chr6_-_149847718	0.698		ZC3H12D	zinc finger CCCH-type containing 12D
chr1_-_42156957	0.690		HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr22_+_30072739	0.686		FLJ20464	hypothetical protein FLJ20464
chr6_-_56824371	0.684		DST	dystonin
chr1_-_28376041	0.683	NM_000952	PTAFR	platelet-activating factor receptor
chr1_-_111544603	0.681
chr22_-_36212160	0.679	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_+_142587973	0.677
chr5_-_54317102	0.675	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr1_-_171442937	0.674	NM_003326	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chrX_-_135690770	0.673		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr16_+_31274020	0.670		ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr14_-_105623358	0.669		IGHA1 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_83052606	0.668	NM_001884	HAPLN1	hyaluronan and proteoglycan link protein 1
chr8_+_70567581	0.653	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr5_+_49997489	0.648	NM_001178055	PARP8	poly (ADP-ribose) polymerase family, member 8
chr7_+_73826244	0.648	NM_000265	NCF1 NCF1B NCF1C	neutrophil cytosolic factor 1 neutrophil cytosolic factor 1B pseudogene neutrophil cytosolic factor 1C pseudogene
chr2_-_213723298	0.648	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr11_+_65027721	0.647
chr1_-_42157077	0.647	NM_001127714 NM_024503	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr7_+_99654806	0.644	NM_024070	PVRIG	poliovirus receptor related immunoglobulin domain containing
chr14_-_106241445	0.644		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr7_+_149842850	0.644	NM_153236	GIMAP7	GTPase, IMAP family member 7
chr3_-_102194938	0.643	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr7_-_44088561	0.640		POLM	polymerase (DNA directed), mu
chr5_-_140875591	0.634		DIAPH1	diaphanous homolog 1 (Drosophila)
chr6_-_170442090	0.631
chr16_+_31274030	0.626		ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr8_-_119703297	0.623		SAMD12	sterile alpha motif domain containing 12
chr2_+_189547323	0.620	NM_000090	COL3A1	collagen, type III, alpha 1
chr11_-_47356479	0.619		SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr15_-_40537002	0.617	NM_022473	ZFP106	zinc finger protein 106 homolog (mouse)
chr15_-_38387357	0.617		PLCB2	phospholipase C, beta 2
chr6_+_44295219	0.617	NM_001078174 NM_004955	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr5_+_155686333	0.616	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr12_-_8656705	0.614	NM_020661	AICDA	activation-induced cytidine deaminase
chr7_-_27186400	0.613	NM_153715	HOXA10	homeobox A10
chr5_+_132037271	0.608	NM_000589 NM_172348	IL4	interleukin 4
chr19_+_57531309	0.602	NM_001161425 NM_001161426 NM_001161427	ZNF610	zinc finger protein 610

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	7.70e-12	GO:0050794	regulation of cellular process
1.22	1.99e-10	GO:0050789	regulation of biological process
1.44	4.19e-10	GO:0048731	system development
1.20	8.01e-10	GO:0065007	biological regulation
1.38	9.43e-09	GO:0048856	anatomical structure development
1.27	1.68e-08	GO:0032501	multicellular organismal process
1.35	6.77e-08	GO:0007275	multicellular organismal development
1.32	1.62e-07	GO:0032502	developmental process
1.54	7.89e-07	GO:0007399	nervous system development
1.21	2.21e-06	GO:0050896	response to stimulus
1.39	4.34e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.45	5.21e-06	GO:0048513	organ development
1.40	6.94e-06	GO:0051252	regulation of RNA metabolic process
1.37	8.50e-06	GO:0010468	regulation of gene expression
1.40	9.68e-06	GO:0006355	regulation of transcription, DNA-dependent
1.36	2.68e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.33	8.99e-05	GO:0031326	regulation of cellular biosynthetic process
1.33	1.25e-04	GO:0009889	regulation of biosynthetic process
1.26	1.71e-04	GO:0023052	signaling
1.41	1.82e-04	GO:0007166	cell surface receptor linked signaling pathway
1.27	4.32e-04	GO:0060255	regulation of macromolecule metabolic process
1.26	4.55e-04	GO:0031323	regulation of cellular metabolic process
1.27	5.85e-04	GO:0007165	signal transduction
1.31	6.09e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26	7.53e-04	GO:0080090	regulation of primary metabolic process
1.48	8.10e-04	GO:0002376	immune system process
1.30	1.11e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.23	2.01e-03	GO:0019222	regulation of metabolic process
1.53	2.32e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.29	2.81e-03	GO:0048518	positive regulation of biological process
1.53	4.11e-03	GO:0022008	neurogenesis
1.33	5.22e-03	GO:0030154	cell differentiation
1.21	5.34e-03	GO:0051716	cellular response to stimulus
1.61	8.44e-03	GO:0010628	positive regulation of gene expression
1.32	9.25e-03	GO:0048869	cellular developmental process
1.63	1.07e-02	GO:0045893	positive regulation of transcription, DNA-dependent
1.52	1.59e-02	GO:0048699	generation of neurons
1.58	1.62e-02	GO:0030182	neuron differentiation
1.55	1.74e-02	GO:0006955	immune response
1.68	2.06e-02	GO:0001775	cell activation
1.28	2.19e-02	GO:0048522	positive regulation of cellular process
1.66	3.27e-02	GO:0007417	central nervous system development
1.08	3.37e-02	GO:0009987	cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.24	2.21e-08	GO:0005634	nucleus
1.17	2.16e-02	GO:0005886	plasma membrane
1.17	3.16e-02	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.38	2.26e-06	GO:0003677	DNA binding
1.61	3.88e-06	GO:0001071	nucleic acid binding transcription factor activity
1.61	3.88e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.56	4.10e-05	GO:0030528	transcription regulator activity
1.26	2.75e-04	GO:0003676	nucleic acid binding
1.92	6.64e-04	GO:0003779	actin binding
1.60	1.39e-03	GO:0043565	sequence-specific DNA binding
1.13	3.60e-03	GO:0005515	protein binding
1.07	3.81e-03	GO:0005488	binding
2.78	1.93e-02	GO:0005089	Rho guanyl-nucleotide exchange factor activity
3.47	2.83e-02	GO:0003823	antigen binding