Motif ID: MZF1.p2

Z-value: 4.833


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637764420.611.2e-02Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_22513043 17.473 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr9_+_108665168 16.599 NM_021224
 ZNF462
zinc finger protein 462
chr2_-_161058120 12.391 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_161058550 11.461 NM_002897
NM_016836
 RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_-_36531958 10.403 NM_020856
 TSHZ3
teashirt zinc finger homeobox 3
chr11_-_127897098 10.083 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr1_-_72521079 9.565


chr5_+_17270781 9.534 BASP1
brain abundant, membrane attached signal protein 1
chr7_-_27120015 8.926 HOXA3
homeobox A3
chr3_-_189354510 8.560 LOC339929
hypothetical LOC339929
chr2_-_216944911 8.333 NM_020814
 MARCH4
membrane-associated ring finger (C3HC4) 4
chr10_-_105604942 8.285 NM_014631
 SH3PXD2A
SH3 and PX domains 2A
chr3_-_121652183 8.240 NM_007085
 FSTL1
follistatin-like 1
chr11_-_127897271 8.146 NM_001162422
NM_005238
 ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr3_+_189354167 8.067 NM_001167672
 LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_64504835 7.970 HMGA2
high mobility group AT-hook 2
chr6_-_10523203 7.885 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_-_126839000 7.698 CTBP2
C-terminal binding protein 2
chr22_-_28972683 7.620 NM_002309
 LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr6_-_75972473 7.499 COL12A1
collagen, type XII, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 173 entries
enrichment   p-value GO term description
1.83 8.86e-03 GO:0042326 negative regulation of phosphorylation
1.78 1.44e-02 GO:2000027 regulation of organ morphogenesis
1.77 2.60e-02 GO:0010563 negative regulation of phosphorus metabolic process
1.77 2.60e-02 GO:0045936 negative regulation of phosphate metabolic process
1.71 8.47e-03 GO:0030326 embryonic limb morphogenesis
1.71 8.47e-03 GO:0035113 embryonic appendage morphogenesis
1.71 3.37e-02 GO:0048706 embryonic skeletal system development
1.67 1.85e-02 GO:0003007 heart morphogenesis
1.63 1.87e-02 GO:0072001 renal system development
1.61 4.30e-03 GO:0060537 muscle tissue development
1.61 1.10e-02 GO:0014706 striated muscle tissue development
1.58 4.01e-03 GO:0001655 urogenital system development
1.57 1.61e-14 GO:0000904 cell morphogenesis involved in differentiation
1.57 2.89e-02 GO:0048705 skeletal system morphogenesis
1.57 3.50e-02 GO:0010639 negative regulation of organelle organization
1.56 8.42e-03 GO:0045165 cell fate commitment
1.55 1.90e-04 GO:0001701 in utero embryonic development
1.54 3.12e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.54 6.08e-06 GO:0001568 blood vessel development
1.53 7.21e-11 GO:0048812 neuron projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
1.74 1.06e-04 GO:0005925 focal adhesion
1.73 4.75e-05 GO:0030055 cell-substrate junction
1.72 1.54e-04 GO:0005924 cell-substrate adherens junction
1.60 1.04e-04 GO:0005912 adherens junction
1.53 5.87e-04 GO:0070161 anchoring junction
1.52 1.12e-05 GO:0016323 basolateral plasma membrane
1.43 2.31e-02 GO:0030424 axon
1.36 4.48e-07 GO:0030054 cell junction
1.32 2.28e-03 GO:0045202 synapse
1.30 8.74e-03 GO:0043005 neuron projection
1.30 3.05e-02 GO:0048471 perinuclear region of cytoplasm
1.21 2.25e-02 GO:0044451 nucleoplasm part
1.17 6.35e-03 GO:0005654 nucleoplasm
1.16 1.78e-05 GO:0005829 cytosol
1.16 2.43e-04 GO:0031981 nuclear lumen
1.14 7.70e-04 GO:0044428 nuclear part
1.13 1.27e-04 GO:0043234 protein complex
1.13 2.17e-03 GO:0043233 organelle lumen
1.12 7.52e-03 GO:0070013 intracellular organelle lumen
1.12 7.80e-03 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.92 1.89e-02 GO:0008013 beta-catenin binding
1.53 1.77e-04 GO:0010843 promoter binding
1.50 5.33e-04 GO:0000975 regulatory region DNA binding
1.50 5.33e-04 GO:0001067 regulatory region nucleic acid binding
1.50 5.33e-04 GO:0044212 transcription regulatory region DNA binding
1.43 4.65e-12 GO:0043565 sequence-specific DNA binding
1.38 2.79e-03 GO:0008134 transcription factor binding
1.34 4.40e-04 GO:0019904 protein domain specific binding
1.33 1.54e-10 GO:0001071 nucleic acid binding transcription factor activity
1.33 1.54e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.32 3.95e-02 GO:0003779 actin binding
1.31 3.28e-09 GO:0030528 transcription regulator activity
1.30 6.07e-04 GO:0008092 cytoskeletal protein binding
1.23 8.07e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 1.04e-02 GO:0019899 enzyme binding
1.23 4.65e-02 GO:0004672 protein kinase activity
1.22 1.63e-02 GO:0016301 kinase activity
1.13 3.91e-19 GO:0005515 protein binding
1.06 7.10e-11 GO:0005488 binding