Motif ID: MZF1.p2

Z-value: 4.833


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_637764420.611.2e-02Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_22513043 17.473 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr9_+_108665168 16.599 NM_021224
ZNF462
zinc finger protein 462
chr2_-_161058120 12.391 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_161058550 11.461 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_-_36531958 10.403 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr11_-_127897098 10.083 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr1_-_72521079 9.565


chr5_+_17270781 9.534 BASP1
brain abundant, membrane attached signal protein 1
chr7_-_27120015 8.926 HOXA3
homeobox A3
chr3_-_189354510 8.560 LOC339929
hypothetical LOC339929
chr2_-_216944911 8.333 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr10_-_105604942 8.285 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr3_-_121652183 8.240 NM_007085
FSTL1
follistatin-like 1
chr11_-_127897271 8.146 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr3_+_189354167 8.067 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_64504835 7.970 HMGA2
high mobility group AT-hook 2
chr6_-_10523203 7.885 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_-_126839000 7.698 CTBP2
C-terminal binding protein 2
chr22_-_28972683 7.620 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr6_-_75972473 7.499 COL12A1
collagen, type XII, alpha 1
chr4_-_158111916 7.384 PDGFC
platelet derived growth factor C
chr10_-_126839056 7.295 NM_001329
CTBP2
C-terminal binding protein 2
chr7_+_55054152 7.275 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr5_-_9599157 7.222 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chrX_+_73557809 7.138 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr4_-_158111995 7.096 NM_016205
PDGFC
platelet derived growth factor C
chr2_+_69093641 7.041 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr13_-_43259032 6.887 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr8_+_95722448 6.845 ESRP1
epithelial splicing regulatory protein 1
chr1_-_72520735 6.779 NM_173808
NEGR1
neuronal growth regulator 1
chr1_+_15957832 6.719 NM_017556
FBLIM1
filamin binding LIM protein 1
chr22_-_34566276 6.568 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr18_+_54682261 6.485 ZNF532
zinc finger protein 532
chr6_+_17501589 6.468 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr6_-_10523424 6.406 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_30361485 6.399 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr12_-_51912101 6.191 NM_000966
RARG
retinoic acid receptor, gamma
chr18_-_55515623 6.165 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr6_-_72187168 6.052 C6orf155
chromosome 6 open reading frame 155
chr10_+_73393998 6.026 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr18_-_55515552 5.986 CCBE1
collagen and calcium binding EGF domains 1
chr1_+_181259317 5.960


chr21_+_46226072 5.933 NM_001848
COL6A1
collagen, type VI, alpha 1
chr1_-_223907283 5.907 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chrX_+_100361588 5.894 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr3_+_23219707 5.727 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr1_+_162795328 5.715 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr2_-_56004366 5.549 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr13_-_39075200 5.511 LHFP
lipoma HMGIC fusion partner
chr5_-_92942680 5.471 FLJ42709
hypothetical LOC441094
chr21_-_27261276 5.457 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_-_24068759 5.419 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr22_-_34566210 5.406 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr9_-_14304036 5.405 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chrX_-_1291526 5.366 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr11_+_36354110 5.364 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr12_+_63958949 5.299 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr17_+_30594192 5.298 NM_144975
SLFN5
schlafen family member 5
chr4_+_81406765 5.295 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr20_+_51022352 5.244 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr4_+_30330963 5.228 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr22_-_34566367 5.219 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr20_+_17498507 5.218 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr6_-_10520592 5.176 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_18255753 5.156 FLJ35934
FLJ35934
chr6_-_10520264 5.154 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_95722575 5.137 ESRP1
epithelial splicing regulatory protein 1
chr17_+_58058783 5.114 MRC2
mannose receptor, C type 2
chr5_-_127901633 5.095 NM_001999
FBN2
fibrillin 2
chr8_+_95722516 5.073 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr12_-_47468985 5.062 NM_020983
ADCY6
adenylate cyclase 6
chr10_+_114699953 5.047 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_+_36436316 5.030 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_92944680 5.028 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr4_-_158111504 5.024 PDGFC
platelet derived growth factor C
chr5_-_73972055 4.947 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr12_-_105056577 4.931 NUAK1
NUAK family, SNF1-like kinase, 1
chr4_+_183302105 4.914 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr16_-_71650034 4.878 NM_001164766
ZFHX3
zinc finger homeobox 3
chr11_+_86189138 4.827 NM_007173
PRSS23
protease, serine, 23
chr7_-_27136876 4.809 NM_002141
HOXA4
homeobox A4
chr19_+_46416975 4.780 AXL
AXL receptor tyrosine kinase
chr4_-_11039600 4.758 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_-_126839546 4.753 NM_001083914
CTBP2
C-terminal binding protein 2
chr5_+_17270474 4.747 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr9_-_14303943 4.694 NFIB
nuclear factor I/B
chr19_-_242335 4.676 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr9_+_138341752 4.674 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr4_-_140696740 4.667 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_+_55054416 4.643 EGFR
epidermal growth factor receptor
chrX_+_154650590 4.633 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr9_-_14303899 4.580 NFIB
nuclear factor I/B
chr12_+_55201854 4.545 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr6_-_42527760 4.537 NM_033502
TRERF1
transcriptional regulating factor 1
chr5_+_82803248 4.521 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr19_-_242168 4.472 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr11_-_27677755 4.418 NM_170734
BDNF
brain-derived neurotrophic factor
chr12_+_63958689 4.394 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr9_-_4289574 4.387 GLIS3
GLIS family zinc finger 3
chr16_-_63713485 4.369 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr7_+_27102508 4.361


chr6_+_121798443 4.359 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr1_-_212791597 4.359 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr16_-_63713466 4.346 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_13240987 4.309 EMP1
epithelial membrane protein 1
chr16_-_63713382 4.298 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr17_-_24069299 4.277 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr14_+_85069217 4.254


chr19_+_12996745 4.227 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_+_77695334 4.192 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr1_+_181258952 4.148 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr19_+_46416938 4.136 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr17_-_69151821 4.132 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr10_+_71231693 4.125 COL13A1
collagen, type XIII, alpha 1
chr17_+_7728819 4.121 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr19_+_46416971 4.085 AXL
AXL receptor tyrosine kinase
chr6_+_116798791 4.084 NM_013352
DSE
dermatan sulfate epimerase
chr12_-_26169074 4.082 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_+_198975227 4.052 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr7_+_78920846 4.040 LOC100505881
hypothetical LOC100505881
chr4_+_30331289 4.034 PCDH7
protocadherin 7
chr9_+_111850770 4.033 AKAP2
A kinase (PRKA) anchor protein 2
chr13_+_113574925 4.030 NM_001143945
GAS6
growth arrest-specific 6
chr11_+_69165119 4.015 CCND1
cyclin D1
chr1_+_218768423 3.996 MARK1
MAP/microtubule affinity-regulating kinase 1
chr9_+_111850698 3.991 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr7_-_78920806 3.989 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_18003401 3.930 NM_005257
GATA6
GATA binding protein 6
chr12_+_74071145 3.920 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr22_+_29974368 3.909 LIMK2
LIM domain kinase 2
chr19_+_43572679 3.902 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr9_-_109291866 3.864 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_-_20684858 3.838 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_127458231 3.836 NM_022143
LRRC4
leucine rich repeat containing 4
chr4_-_115120251 3.831 NM_024590
ARSJ
arylsulfatase family, member J
chr10_-_35143900 3.825 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr13_+_72531098 3.808 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr9_-_4290028 3.803 NM_001042413
GLIS3
GLIS family zinc finger 3
chr22_-_26527469 3.795 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr8_+_123863224 3.778 ZHX2
zinc fingers and homeoboxes 2
chr1_-_85816520 3.760 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_+_69165065 3.747 CCND1
cyclin D1
chr4_-_86106567 3.735 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr1_+_199884152 3.710 NAV1
neuron navigator 1
chr12_-_94708641 3.710 NM_021229
NTN4
netrin 4
chr8_-_127639647 3.707 FAM84B
family with sequence similarity 84, member B
chr7_+_28415495 3.704 LOC401317
hypothetical LOC401317
chr19_+_46417117 3.687 AXL
AXL receptor tyrosine kinase
chr9_-_109291575 3.667 KLF4
Kruppel-like factor 4 (gut)
chr2_+_36436873 3.666 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_+_69165018 3.657 NM_053056
CCND1
cyclin D1
chr4_-_102487506 3.650 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_68470585 3.636 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr14_-_52487558 3.629 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr9_-_20612433 3.627 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr19_-_56178882 3.553 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr4_+_145786622 3.551 NM_022475
HHIP
hedgehog interacting protein
chr3_-_55496370 3.540 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr11_+_35596310 3.532 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr20_+_1823825 3.531 NM_001040023
SIRPA
signal-regulatory protein alpha
chr17_+_52026058 3.510 NM_005450
NOG
noggin
chr12_+_74071116 3.509 GLIPR1L2
GLI pathogenesis-related 1 like 2
chr18_-_22382497 3.494 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr15_+_66658626 3.486 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr19_+_46417099 3.486 AXL
AXL receptor tyrosine kinase
chr2_+_5750229 3.478 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr20_+_1823534 3.471 SIRPA
signal-regulatory protein alpha
chr6_-_75972286 3.462 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr12_+_52618815 3.458 NM_017410
HOXC13
homeobox C13
chr20_+_1824006 3.456 SIRPA
signal-regulatory protein alpha
chr13_-_109236897 3.446 NM_003749
IRS2
insulin receptor substrate 2
chr12_-_94708477 3.440 NTN4
netrin 4
chr16_-_52877868 3.403 NM_024336
IRX3
iroquois homeobox 3
chr19_+_12996830 3.376 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr18_-_51406359 3.363 TCF4
transcription factor 4
chr8_-_11096257 3.343 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr12_-_93568336 3.334 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr7_+_114349376 3.323 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr12_+_13240983 3.309 EMP1
epithelial membrane protein 1
chr12_-_105165805 3.302 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr8_+_37672427 3.269 NM_025069
ZNF703
zinc finger protein 703
chr7_-_19123765 3.269 TWIST1
twist homolog 1 (Drosophila)
chr9_+_117955890 3.269 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_+_70952729 3.243 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr7_+_28692122 3.236 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr6_-_170441493 3.236 NM_005618
DLL1
delta-like 1 (Drosophila)
chr9_-_4289915 3.230 GLIS3
GLIS family zinc finger 3
chr10_+_71231649 3.227 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr2_+_85834111 3.197 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr2_-_207738858 3.187 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_143750988 3.186 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr18_+_44319365 3.172 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr20_+_1822943 3.165 SIRPA
signal-regulatory protein alpha
chr15_+_97010219 3.122 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr13_-_39075355 3.111 NM_005780
LHFP
lipoma HMGIC fusion partner
chrX_+_66680593 3.111 NM_000044
AR
androgen receptor
chr13_-_39075304 3.108 LHFP
lipoma HMGIC fusion partner
chr8_-_75396016 3.092 NM_020647
JPH1
junctophilin 1
chr2_+_28469864 3.074 FOSL2
FOS-like antigen 2
chrX_-_62891730 3.066 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 1.20e-22 GO:0009653 anatomical structure morphogenesis
1.08 6.38e-19 GO:0009987 cellular process
1.12 1.60e-18 GO:0065007 biological regulation
1.20 1.02e-17 GO:0032502 developmental process
1.13 1.29e-17 GO:0050794 regulation of cellular process
1.21 3.15e-17 GO:0007275 multicellular organismal development
1.12 5.36e-17 GO:0050789 regulation of biological process
1.26 5.75e-17 GO:0048522 positive regulation of cellular process
1.24 8.72e-17 GO:0048731 system development
1.22 1.75e-16 GO:0048856 anatomical structure development
1.33 5.94e-16 GO:0007399 nervous system development
1.24 7.25e-16 GO:0048518 positive regulation of biological process
1.42 1.54e-14 GO:0022008 neurogenesis
1.57 1.61e-14 GO:0000904 cell morphogenesis involved in differentiation
1.50 1.61e-14 GO:0032989 cellular component morphogenesis
1.27 2.13e-14 GO:0030154 cell differentiation
1.26 8.25e-14 GO:0048869 cellular developmental process
1.46 2.42e-13 GO:0030182 neuron differentiation
1.40 2.88e-13 GO:0048468 cell development
1.50 3.42e-13 GO:0000902 cell morphogenesis
1.40 1.69e-12 GO:0048699 generation of neurons
1.52 8.64e-12 GO:0031175 neuron projection development
1.17 1.32e-11 GO:0031323 regulation of cellular metabolic process
1.23 2.23e-11 GO:0048523 negative regulation of cellular process
1.47 2.66e-11 GO:0048666 neuron development
1.54 3.12e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.22 4.21e-11 GO:0048519 negative regulation of biological process
1.53 7.21e-11 GO:0048812 neuron projection morphogenesis
1.17 1.10e-10 GO:0080090 regulation of primary metabolic process
1.43 1.92e-10 GO:0030030 cell projection organization
1.53 3.06e-10 GO:0007409 axonogenesis
1.48 6.74e-10 GO:0048858 cell projection morphogenesis
1.17 7.10e-10 GO:0060255 regulation of macromolecule metabolic process
1.47 1.11e-09 GO:0032990 cell part morphogenesis
1.35 1.28e-09 GO:0050793 regulation of developmental process
1.13 2.26e-09 GO:0043170 macromolecule metabolic process
1.32 8.70e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.36 1.12e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.35 1.55e-08 GO:0051128 regulation of cellular component organization
1.15 1.72e-08 GO:0023052 signaling
1.19 1.99e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 3.01e-08 GO:0009790 embryo development
1.14 3.27e-08 GO:0019222 regulation of metabolic process
1.39 4.23e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.13 5.84e-08 GO:0044260 cellular macromolecule metabolic process
1.28 7.35e-08 GO:0031325 positive regulation of cellular metabolic process
1.35 7.41e-08 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 9.27e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.50 1.28e-07 GO:0043009 chordate embryonic development
1.37 1.31e-07 GO:0051254 positive regulation of RNA metabolic process
1.10 1.32e-07 GO:0044238 primary metabolic process
1.17 1.79e-07 GO:0031326 regulation of cellular biosynthetic process
1.17 1.82e-07 GO:0009889 regulation of biosynthetic process
1.49 2.18e-07 GO:0009792 embryo development ending in birth or egg hatching
1.26 2.24e-07 GO:0009893 positive regulation of metabolic process
1.38 2.62e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.21 4.69e-07 GO:0048513 organ development
1.17 4.93e-07 GO:0010468 regulation of gene expression
1.32 5.69e-07 GO:0031328 positive regulation of cellular biosynthetic process
1.27 5.99e-07 GO:0010604 positive regulation of macromolecule metabolic process
1.22 7.40e-07 GO:0023051 regulation of signaling
1.35 8.74e-07 GO:0010628 positive regulation of gene expression
1.31 1.01e-06 GO:0009891 positive regulation of biosynthetic process
1.33 1.11e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.42 1.11e-06 GO:0072358 cardiovascular system development
1.42 1.11e-06 GO:0072359 circulatory system development
1.33 1.11e-06 GO:2000026 regulation of multicellular organismal development
1.25 1.42e-06 GO:0051239 regulation of multicellular organismal process
1.24 1.64e-06 GO:0009966 regulation of signal transduction
1.34 2.07e-06 GO:0045595 regulation of cell differentiation
1.13 2.15e-06 GO:0051716 cellular response to stimulus
1.14 2.24e-06 GO:0007165 signal transduction
1.30 2.45e-06 GO:0031324 negative regulation of cellular metabolic process
1.16 2.53e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 3.14e-06 GO:0009887 organ morphogenesis
1.16 3.41e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.08 5.14e-06 GO:0008152 metabolic process
1.54 6.08e-06 GO:0001568 blood vessel development
1.27 6.92e-06 GO:0009892 negative regulation of metabolic process
1.17 1.12e-05 GO:0051252 regulation of RNA metabolic process
1.38 1.16e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 1.19e-05 GO:0071840 cellular component organization or biogenesis
1.13 2.17e-05 GO:0016043 cellular component organization
1.28 2.31e-05 GO:0009888 tissue development
1.28 2.44e-05 GO:0006351 transcription, DNA-dependent
1.49 3.31e-05 GO:0001944 vasculature development
1.26 3.79e-05 GO:0032879 regulation of localization
1.09 4.00e-05 GO:0044237 cellular metabolic process
1.48 4.06e-05 GO:0048729 tissue morphogenesis
1.15 4.62e-05 GO:0071842 cellular component organization at cellular level
1.45 5.12e-05 GO:0007411 axon guidance
1.27 5.23e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.15 8.04e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.38 8.67e-05 GO:0048646 anatomical structure formation involved in morphogenesis
1.18 1.09e-04 GO:0048583 regulation of response to stimulus
1.42 1.17e-04 GO:0048598 embryonic morphogenesis
1.32 1.25e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.38 1.27e-04 GO:0051094 positive regulation of developmental process
1.30 1.49e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.37 1.60e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.30 1.61e-04 GO:0009890 negative regulation of biosynthetic process
1.55 1.90e-04 GO:0001701 in utero embryonic development
1.29 1.97e-04 GO:0006468 protein phosphorylation
1.16 2.33e-04 GO:0006355 regulation of transcription, DNA-dependent
1.31 2.44e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 3.09e-04 GO:0035295 tube development
1.42 3.12e-04 GO:0007389 pattern specification process
1.50 4.19e-04 GO:0051129 negative regulation of cellular component organization
1.13 5.09e-04 GO:0019538 protein metabolic process
1.17 5.10e-04 GO:0006464 protein modification process
1.17 8.40e-04 GO:0010467 gene expression
1.25 1.33e-03 GO:0008219 cell death
1.42 1.54e-03 GO:0051130 positive regulation of cellular component organization
1.23 1.64e-03 GO:0032774 RNA biosynthetic process
1.30 1.98e-03 GO:0010629 negative regulation of gene expression
1.41 2.11e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.24 2.41e-03 GO:0016265 death
1.22 2.84e-03 GO:0032268 regulation of cellular protein metabolic process
1.13 3.07e-03 GO:0009058 biosynthetic process
1.13 3.09e-03 GO:0044267 cellular protein metabolic process
1.22 3.44e-03 GO:0006793 phosphorus metabolic process
1.22 3.44e-03 GO:0006796 phosphate metabolic process
1.58 4.01e-03 GO:0001655 urogenital system development
1.14 4.23e-03 GO:0044249 cellular biosynthetic process
1.39 4.24e-03 GO:0001501 skeletal system development
1.61 4.30e-03 GO:0060537 muscle tissue development
1.47 4.42e-03 GO:0002009 morphogenesis of an epithelium
1.26 4.49e-03 GO:0006915 apoptosis
1.16 5.11e-03 GO:0007166 cell surface receptor linked signaling pathway
1.45 5.79e-03 GO:0003002 regionalization
1.14 7.35e-03 GO:0042221 response to chemical stimulus
1.21 8.17e-03 GO:0009605 response to external stimulus
1.56 8.42e-03 GO:0045165 cell fate commitment
1.71 8.47e-03 GO:0030326 embryonic limb morphogenesis
1.71 8.47e-03 GO:0035113 embryonic appendage morphogenesis
1.36 8.49e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.83 8.86e-03 GO:0042326 negative regulation of phosphorylation
1.37 9.25e-03 GO:0045597 positive regulation of cell differentiation
1.41 1.04e-02 GO:0010608 posttranscriptional regulation of gene expression
1.16 1.04e-02 GO:0016070 RNA metabolic process
1.29 1.10e-02 GO:0051253 negative regulation of RNA metabolic process
1.61 1.10e-02 GO:0014706 striated muscle tissue development
1.29 1.12e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.20 1.15e-02 GO:0051246 regulation of protein metabolic process
1.23 1.17e-02 GO:0016310 phosphorylation
1.37 1.39e-02 GO:0051093 negative regulation of developmental process
1.25 1.41e-02 GO:0012501 programmed cell death
1.27 1.42e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.78 1.44e-02 GO:2000027 regulation of organ morphogenesis
1.14 1.47e-02 GO:0065008 regulation of biological quality
1.45 1.47e-02 GO:0048514 blood vessel morphogenesis
1.40 1.48e-02 GO:0061061 muscle structure development
1.27 1.58e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 1.59e-02 GO:0009059 macromolecule biosynthetic process
1.16 1.73e-02 GO:0034645 cellular macromolecule biosynthetic process
1.67 1.85e-02 GO:0003007 heart morphogenesis
1.63 1.87e-02 GO:0072001 renal system development
1.10 2.16e-02 GO:0051179 localization
1.33 2.31e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.31 2.34e-02 GO:0032583 regulation of gene-specific transcription
1.25 2.39e-02 GO:0042325 regulation of phosphorylation
1.26 2.59e-02 GO:0001932 regulation of protein phosphorylation
1.77 2.60e-02 GO:0010563 negative regulation of phosphorus metabolic process
1.77 2.60e-02 GO:0045936 negative regulation of phosphate metabolic process
1.57 2.89e-02 GO:0048705 skeletal system morphogenesis
1.40 3.05e-02 GO:0045596 negative regulation of cell differentiation
1.71 3.37e-02 GO:0048706 embryonic skeletal system development
1.14 3.47e-02 GO:0043412 macromolecule modification
1.24 3.50e-02 GO:0019220 regulation of phosphate metabolic process
1.24 3.50e-02 GO:0051174 regulation of phosphorus metabolic process
1.57 3.50e-02 GO:0010639 negative regulation of organelle organization
1.41 4.45e-02 GO:0048568 embryonic organ development
1.19 4.64e-02 GO:0010941 regulation of cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 5.08e-12 GO:0044424 intracellular part
1.06 2.47e-10 GO:0005622 intracellular
1.11 9.03e-09 GO:0005634 nucleus
1.08 1.56e-08 GO:0005737 cytoplasm
1.06 3.15e-08 GO:0043226 organelle
1.07 4.20e-08 GO:0043227 membrane-bounded organelle
1.07 5.05e-08 GO:0043231 intracellular membrane-bounded organelle
1.06 6.62e-08 GO:0043229 intracellular organelle
1.36 4.48e-07 GO:0030054 cell junction
1.03 9.42e-07 GO:0044464 cell part
1.03 1.04e-06 GO:0005623 cell
1.52 1.12e-05 GO:0016323 basolateral plasma membrane
1.16 1.78e-05 GO:0005829 cytosol
1.73 4.75e-05 GO:0030055 cell-substrate junction
1.60 1.04e-04 GO:0005912 adherens junction
1.74 1.06e-04 GO:0005925 focal adhesion
1.13 1.27e-04 GO:0043234 protein complex
1.72 1.54e-04 GO:0005924 cell-substrate adherens junction
1.16 2.43e-04 GO:0031981 nuclear lumen
1.53 5.87e-04 GO:0070161 anchoring junction
1.14 7.70e-04 GO:0044428 nuclear part
1.13 2.17e-03 GO:0043233 organelle lumen
1.32 2.28e-03 GO:0045202 synapse
1.10 2.63e-03 GO:0032991 macromolecular complex
1.17 6.35e-03 GO:0005654 nucleoplasm
1.12 7.52e-03 GO:0070013 intracellular organelle lumen
1.12 7.80e-03 GO:0031974 membrane-enclosed lumen
1.30 8.74e-03 GO:0043005 neuron projection
1.21 2.25e-02 GO:0044451 nucleoplasm part
1.43 2.31e-02 GO:0030424 axon
1.30 3.05e-02 GO:0048471 perinuclear region of cytoplasm
1.11 3.93e-02 GO:0044459 plasma membrane part
1.06 4.52e-02 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 3.91e-19 GO:0005515 protein binding
1.43 4.65e-12 GO:0043565 sequence-specific DNA binding
1.06 7.10e-11 GO:0005488 binding
1.33 1.54e-10 GO:0001071 nucleic acid binding transcription factor activity
1.33 1.54e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 3.28e-09 GO:0030528 transcription regulator activity
1.53 1.77e-04 GO:0010843 promoter binding
1.34 4.40e-04 GO:0019904 protein domain specific binding
1.50 5.33e-04 GO:0000975 regulatory region DNA binding
1.50 5.33e-04 GO:0001067 regulatory region nucleic acid binding
1.50 5.33e-04 GO:0044212 transcription regulatory region DNA binding
1.30 6.07e-04 GO:0008092 cytoskeletal protein binding
1.38 2.79e-03 GO:0008134 transcription factor binding
1.23 8.07e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 1.04e-02 GO:0019899 enzyme binding
1.22 1.63e-02 GO:0016301 kinase activity
1.92 1.89e-02 GO:0008013 beta-catenin binding
1.32 3.95e-02 GO:0003779 actin binding
1.23 4.65e-02 GO:0004672 protein kinase activity