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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 5.793

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_101485946	11.780	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr13_-_109757442	10.059	NM_001845	COL4A1	collagen, type IV, alpha 1
chr13_+_109757593	9.313	NM_001846	COL4A2	collagen, type IV, alpha 2
chr2_+_9532087	6.725	NM_001039613	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr14_+_105012106	6.695	NM_001312	CRIP2	cysteine-rich protein 2
chrX_+_9943793	6.319	NM_015691	WWC3	WWC family member 3
chr12_+_26003218	6.005	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_-_160972606	5.935		RBMS1	RNA binding motif, single stranded interacting protein 1
chr4_-_24523605	5.776	NM_001130726	CCDC149	coiled-coil domain containing 149
chr1_-_85703198	5.310		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr14_+_92049396	5.258	NM_024832	RIN3	Ras and Rab interactor 3
chr6_+_3696224	5.081
chr3_+_61522310	5.056		PTPRG	protein tyrosine phosphatase, receptor type, G
chr4_-_177950658	4.956	NM_005429	VEGFC	vascular endothelial growth factor C
chr3_+_11171213	4.905	NM_001098212	HRH1	histamine receptor H1
chr7_-_81910956	4.857	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr9_-_135847106	4.848	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr13_+_97593711	4.757		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr14_+_54104099	4.709		SAMD4A	sterile alpha motif domain containing 4A
chr2_+_235525355	4.700	NM_014521	SH3BP4	SH3-domain binding protein 4
chr2_-_112907577	4.699	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr2_+_238200922	4.616	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr2_+_109112428	4.605	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr11_-_44928803	4.596	NM_001076787 NM_006034	TP53I11	tumor protein p53 inducible protein 11
chr1_-_223907283	4.545	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr9_-_21549696	4.493		LOC554202	hypothetical LOC554202
chr6_-_112301123	4.465	NM_002037	FYN	FYN oncogene related to SRC, FGR, YES
chr5_+_14196287	4.355	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr18_+_7557313	4.353	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr12_-_94708477	4.294		NTN4	netrin 4
chr4_-_141896920	4.287	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr5_+_92946348	4.244		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr2_-_127580975	4.236	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr8_+_38733913	4.121		TACC1	transforming, acidic coiled-coil containing protein 1
chr16_-_79395379	4.114	NM_152342	CDYL2	chromodomain protein, Y-like 2
chr2_+_29191711	4.088	NM_024692	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr1_-_95165089	4.042	NM_001839	CNN3	calponin 3, acidic
chr1_+_17738863	4.027	NM_018125	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr13_-_100866706	4.013	NM_052867	NALCN	sodium leak channel, non-selective
chr9_+_123501186	4.006		DAB2IP	DAB2 interacting protein
chr3_+_61522219	3.995	NM_002841	PTPRG	protein tyrosine phosphatase, receptor type, G
chr20_+_56701224	3.938	NM_024663	NPEPL1	aminopeptidase-like 1
chr10_+_124124196	3.896		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr20_-_17459973	3.817	NM_001195	BFSP1	beaded filament structural protein 1, filensin
chr7_-_27136876	3.810	NM_002141	HOXA4	homeobox A4
chr7_-_29995809	3.765	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr1_-_8008934	3.754		ERRFI1	ERBB receptor feedback inhibitor 1
chr6_+_147871477	3.746	NM_001030060	SAMD5	sterile alpha motif domain containing 5
chr12_+_20413445	3.729	NM_000921	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr1_-_56817568	3.709		PPAP2B	phosphatidic acid phosphatase type 2B
chr7_-_81910740	3.685		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr20_-_49612574	3.645	NM_001136021	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr9_-_13269562	3.615		MPDZ	multiple PDZ domain protein
chr2_+_23461802	3.613	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr2_+_241586927	3.540	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr3_+_44878380	3.527	NM_144638	TMEM42	transmembrane protein 42
chr2_-_175578156	3.517	NM_001025201 NM_001822	CHN1	chimerin (chimaerin) 1
chr15_-_49174107	3.515		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr13_+_97593469	3.464		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr9_+_128128913	3.452	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr10_+_128583984	3.448	NM_001380	DOCK1	dedicator of cytokinesis 1
chr4_+_151218862	3.431	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr2_-_175255717	3.395	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr1_-_115682374	3.381	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr8_-_7200278	3.377		FAM66B	family with sequence similarity 66, member B
chr14_+_85069217	3.352
chr12_-_94708641	3.340	NM_021229	NTN4	netrin 4
chr9_+_136673534	3.337		COL5A1	collagen, type V, alpha 1
chr1_-_95165037	3.325		CNN3	calponin 3, acidic
chr2_-_165406173	3.317	NM_014900	COBLL1	COBL-like 1
chr14_+_54104383	3.290	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr22_-_19122047	3.288		SCARF2	scavenger receptor class F, member 2
chr21_-_43671355	3.276	NM_173354	SIK1	salt-inducible kinase 1
chr4_+_19864332	3.270	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chrX_+_135057202	3.258	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr11_-_110088330	3.239	NM_020809	ARHGAP20	Rho GTPase activating protein 20
chr6_+_72055235	3.236		OGFRL1	opioid growth factor receptor-like 1
chr16_-_71639670	3.217	NM_006885	ZFHX3	zinc finger homeobox 3
chr1_-_56817717	3.216		PPAP2B	phosphatidic acid phosphatase type 2B
chr18_+_65219114	3.216	NM_152721	DOK6	docking protein 6
chr12_+_95112131	3.215	NM_005230	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr6_+_72055197	3.192	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr17_+_58058774	3.186		MRC2	mannose receptor, C type 2
chr1_-_56817823	3.185	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr13_-_100866839	3.184		NALCN	sodium leak channel, non-selective
chr18_+_66107116	3.181	NM_004232	SOCS6	suppressor of cytokine signaling 6
chr5_-_171643399	3.149	NM_152277	UBTD2	ubiquitin domain containing 2
chr8_+_17398940	3.141	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr16_+_85158357	3.094	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr6_+_72055229	3.080		OGFRL1	opioid growth factor receptor-like 1
chr4_+_184257337	3.079	NM_024949	WWC2	WW and C2 domain containing 2
chr13_-_39075304	3.071		LHFP	lipoma HMGIC fusion partner
chr14_+_58174489	3.066	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr12_+_95112385	3.062		ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr8_-_41286088	3.050	NM_003012	SFRP1	secreted frizzled-related protein 1
chr17_-_74432671	3.049		TIMP2	TIMP metallopeptidase inhibitor 2
chr8_-_93184629	3.042	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_-_49612745	3.032		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr15_-_53667800	3.014		PYGO1	pygopus homolog 1 (Drosophila)
chr14_-_29466562	3.007	NM_002742	PRKD1	protein kinase D1
chr1_-_234294997	3.003		NID1	nidogen 1
chr5_-_146869613	2.992		DPYSL3	dihydropyrimidinase-like 3
chr1_+_15957832	2.983	NM_017556	FBLIM1	filamin binding LIM protein 1
chr9_-_110815542	2.978	NM_003798	CTNNAL1	catenin (cadherin-associated protein), alpha-like 1
chr8_-_48813236	2.965		CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr12_-_105165805	2.962	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr4_-_114902285	2.959	NM_001221 NM_172114 NM_172115 NM_172127 NM_172128 NM_172129	CAMK2D	calcium/calmodulin-dependent protein kinase II delta
chr17_+_26322168	2.949		RNF135	ring finger protein 135
chr17_-_74433048	2.946	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr4_-_122063118	2.945	NM_018699	PRDM5	PR domain containing 5
chr17_+_58058783	2.944		MRC2	mannose receptor, C type 2
chr5_-_58370693	2.941	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr8_+_32525269	2.927	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr6_+_1335067	2.925	NM_001452	FOXF2	forkhead box F2
chr22_-_19122107	2.917	NM_153334 NM_182895	SCARF2	scavenger receptor class F, member 2
chr17_+_26322081	2.901	NM_001184992 NM_032322 NM_197939	RNF135	ring finger protein 135
chr2_-_161058120	2.894		RBMS1	RNA binding motif, single stranded interacting protein 1
chr5_-_146869811	2.889	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr1_+_181258952	2.889	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr9_-_71476917	2.864	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr12_+_3056781	2.850	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr6_+_11646472	2.847	NM_001100829	TMEM170B	transmembrane protein 170B
chr11_-_110088097	2.834		ARHGAP20	Rho GTPase activating protein 20
chr16_+_85101605	2.831	NM_001451	FOXF1	forkhead box F1
chr17_+_11864841	2.822	NM_003010	MAP2K4	mitogen-activated protein kinase kinase 4
chr3_-_147451509	2.821		PLSCR4	phospholipid scramblase 4
chr16_-_62573	2.797	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr1_-_8008979	2.786	NM_018948	ERRFI1	ERBB receptor feedback inhibitor 1
chr18_+_75540786	2.785	NM_004715 NM_048368	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr6_-_105691235	2.785	NM_007073	BVES	blood vessel epicardial substance
chr7_-_131911808	2.782	NM_001105543 NM_020911	PLXNA4	plexin A4
chr20_+_39199542	2.780	NM_002660 NM_182811	PLCG1	phospholipase C, gamma 1
chr3_-_147451648	2.756	NM_001128306 NM_001177304 NM_020353	PLSCR4	phospholipid scramblase 4
chr5_-_16989290	2.756		MYO10	myosin X
chr7_+_79602023	2.754	NM_002069	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr19_-_1188840	2.751	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr21_+_25856311	2.751		MIR155HG	MIR155 host gene (non-protein coding)
chr10_+_71232281	2.746		COL13A1	collagen, type XIII, alpha 1
chr7_+_288195	2.728		FAM20C	family with sequence similarity 20, member C
chr10_+_112247614	2.722	NM_004419	DUSP5	dual specificity phosphatase 5
chr17_+_52026058	2.719	NM_005450	NOG	noggin
chr10_-_30065760	2.715		SVIL	supervillin
chr6_+_1556543	2.707		FOXC1	forkhead box C1
chr5_+_10617431	2.692	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr10_-_14686243	2.676		FAM107B	family with sequence similarity 107, member B
chr5_-_16989371	2.675	NM_012334	MYO10	myosin X
chr15_+_29406335	2.661	NM_015995	KLF13	Kruppel-like factor 13
chr18_-_20231709	2.642		OSBPL1A	oxysterol binding protein-like 1A
chr16_+_85101734	2.637		FOXF1	forkhead box F1
chr7_-_27162688	2.633	NM_006896	HOXA7	homeobox A7
chr15_-_81744469	2.616	NM_001717	BNC1	basonuclin 1
chr21_+_45649719	2.616
chr2_-_235070431	2.616	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr8_+_142207866	2.614	NM_014957	DENND3	DENN/MADD domain containing 3
chrX_+_149282097	2.602	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr1_+_10193267	2.599	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr12_-_24606616	2.598	NM_152989	SOX5	SRY (sex determining region Y)-box 5
chr14_+_51188289	2.591	NM_152330	FRMD6	FERM domain containing 6
chr17_-_74432800	2.574		TIMP2	TIMP metallopeptidase inhibitor 2
chr16_-_86082818	2.574	NM_015144	ZCCHC14	zinc finger, CCHC domain containing 14
chr7_+_55054416	2.573		EGFR	epidermal growth factor receptor
chr3_-_126257425	2.572	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr14_+_95575319	2.562		C14orf132	chromosome 14 open reading frame 132
chr1_-_92124201	2.557	NM_001195683 NM_003243	TGFBR3	transforming growth factor, beta receptor III
chr6_-_143307976	2.554	NM_006734	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr14_-_89155078	2.547	NM_001085471	FOXN3	forkhead box N3
chr11_+_109469296	2.538	NM_033390	ZC3H12C	zinc finger CCCH-type containing 12C
chr22_-_41446740	2.535	NM_017436	A4GALT	alpha 1,4-galactosyltransferase
chr6_+_139055244	2.535		FLJ46906	hypothetical LOC441172
chr8_+_22492586	2.529		PDLIM2	PDZ and LIM domain 2 (mystique)
chr3_-_126414252	2.522	NM_024628	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr14_+_63389360	2.510	NM_015180 NM_182914	SYNE2	spectrin repeat containing, nuclear envelope 2
chr11_+_64838882	2.501	NM_006779	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2
chr3_+_30623376	2.480		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr16_+_2510323	2.471	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chr5_+_76047536	2.463	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr1_-_234295117	2.463		NID1	nidogen 1
chr13_+_26029879	2.451		WASF3	WAS protein family, member 3
chr21_+_32706615	2.447	NM_058187	C21orf63	chromosome 21 open reading frame 63
chr13_-_39075355	2.447	NM_005780	LHFP	lipoma HMGIC fusion partner
chr7_+_55054152	2.444	NM_005228 NM_201282 NM_201283 NM_201284	EGFR	epidermal growth factor receptor
chr6_-_105691675	2.442		BVES	blood vessel epicardial substance
chr6_+_139391511	2.438	NM_021243	C6orf115	chromosome 6 open reading frame 115
chr1_+_208472817	2.434	NM_019605	SERTAD4	SERTA domain containing 4
chr8_-_94781836	2.431		LOC642924	hypothetical LOC642924
chr11_+_12355600	2.426	NM_018222	PARVA	parvin, alpha
chr18_-_24011349	2.424	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_165406098	2.418		COBLL1	COBL-like 1
chr9_+_136673464	2.414	NM_000093	COL5A1	collagen, type V, alpha 1
chr8_-_145090892	2.407	NM_201381	PLEC	plectin
chr15_+_66658626	2.403	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr2_+_54537842	2.399		SPTBN1	spectrin, beta, non-erythrocytic 1
chr10_+_124124083	2.396	NM_001001974	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_+_288051	2.382	NM_020223	FAM20C	family with sequence similarity 20, member C
chr8_+_27547379	2.377	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr11_+_86189138	2.374	NM_007173	PRSS23	protease, serine, 23
chr11_+_19691397	2.369	NM_145117 NM_182964	NAV2	neuron navigator 2
chr6_+_3697328	2.360
chr2_-_239987557	2.328	NM_006037	HDAC4	histone deacetylase 4
chr1_-_56817802	2.324		PPAP2B	phosphatidic acid phosphatase type 2B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.41	1.70e-17	GO:0023051	regulation of signaling
1.44	2.36e-17	GO:0009966	regulation of signal transduction
1.54	2.42e-16	GO:0022008	neurogenesis
1.09	7.52e-16	GO:0009987	cellular process
1.15	1.35e-15	GO:0050794	regulation of cellular process
1.33	3.44e-15	GO:0030154	cell differentiation
1.54	4.59e-15	GO:0048699	generation of neurons
1.40	7.04e-15	GO:0007399	nervous system development
1.24	7.84e-15	GO:0007275	multicellular organismal development
1.33	8.43e-15	GO:0048869	cellular developmental process
1.22	6.11e-14	GO:0032502	developmental process
1.69	8.67e-14	GO:0000904	cell morphogenesis involved in differentiation
1.64	9.86e-14	GO:0048666	neuron development
1.73	1.63e-13	GO:0048667	cell morphogenesis involved in neuron differentiation
1.72	2.55e-13	GO:0048812	neuron projection morphogenesis
1.31	3.09e-13	GO:0048523	negative regulation of cellular process
1.73	3.81e-13	GO:0007409	axonogenesis
1.37	3.97e-13	GO:0009653	anatomical structure morphogenesis
1.61	5.67e-13	GO:0000902	cell morphogenesis
1.13	8.13e-13	GO:0050789	regulation of biological process
1.56	1.15e-12	GO:0030182	neuron differentiation
1.48	1.16e-12	GO:0048468	cell development
1.66	2.84e-12	GO:0031175	neuron projection development
1.65	3.20e-12	GO:0048858	cell projection morphogenesis
1.28	3.37e-12	GO:0048519	negative regulation of biological process
1.63	9.61e-12	GO:0032990	cell part morphogenesis
1.24	4.44e-11	GO:0048731	system development
1.12	4.50e-11	GO:0065007	biological regulation
1.55	5.09e-11	GO:0032989	cellular component morphogenesis
1.30	5.50e-11	GO:0048583	regulation of response to stimulus
1.54	8.19e-11	GO:0030030	cell projection organization
1.26	1.36e-10	GO:0048522	positive regulation of cellular process
1.22	1.56e-10	GO:0048856	anatomical structure development
1.23	8.32e-10	GO:0048518	positive regulation of biological process
1.51	1.18e-09	GO:0007167	enzyme linked receptor protein signaling pathway
1.19	2.35e-09	GO:0031323	regulation of cellular metabolic process
1.20	3.71e-09	GO:0016043	cellular component organization
1.70	5.62e-09	GO:0007411	axon guidance
1.19	6.59e-09	GO:0080090	regulation of primary metabolic process
1.38	7.64e-09	GO:0010646	regulation of cell communication
1.22	3.04e-08	GO:0071842	cellular component organization at cellular level
1.18	1.00e-07	GO:0071840	cellular component organization or biogenesis
1.18	2.70e-07	GO:0060255	regulation of macromolecule metabolic process
1.30	4.20e-07	GO:0035556	intracellular signal transduction
1.20	6.24e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.16	6.63e-07	GO:0019222	regulation of metabolic process
1.25	1.38e-06	GO:0006464	protein modification process
1.51	1.58e-06	GO:0072358	cardiovascular system development
1.51	1.58e-06	GO:0072359	circulatory system development
1.41	3.87e-06	GO:0009890	negative regulation of biosynthetic process
1.57	4.12e-06	GO:0051056	regulation of small GTPase mediated signal transduction
1.34	6.53e-06	GO:0009892	negative regulation of metabolic process
1.34	6.95e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.17	7.77e-06	GO:0007165	signal transduction
1.23	8.89e-06	GO:0043412	macromolecule modification
1.35	1.12e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.20	1.18e-05	GO:0010468	regulation of gene expression
1.38	1.42e-05	GO:2000026	regulation of multicellular organismal development
1.34	1.69e-05	GO:0031324	negative regulation of cellular metabolic process
1.40	1.74e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.35	1.98e-05	GO:0040011	locomotion
1.41	3.01e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.11	3.07e-05	GO:0044237	cellular metabolic process
1.45	3.08e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.66	3.15e-05	GO:0046578	regulation of Ras protein signal transduction
1.15	4.64e-05	GO:0023052	signaling
1.40	5.01e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.33	5.74e-05	GO:0050793	regulation of developmental process
1.38	8.64e-05	GO:0051254	positive regulation of RNA metabolic process
1.38	9.36e-05	GO:0045595	regulation of cell differentiation
1.59	9.70e-05	GO:0001944	vasculature development
1.44	1.48e-04	GO:0048585	negative regulation of response to stimulus
1.17	1.58e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.48	1.73e-04	GO:0009968	negative regulation of signal transduction
1.17	1.94e-04	GO:0009889	regulation of biosynthetic process
1.39	2.03e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.17	2.07e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37	2.19e-04	GO:0010628	positive regulation of gene expression
1.39	2.35e-04	GO:0010629	negative regulation of gene expression
1.18	2.36e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.44	2.47e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.64	2.56e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.17	2.70e-04	GO:0031326	regulation of cellular biosynthetic process
1.30	3.09e-04	GO:0006793	phosphorus metabolic process
1.30	3.09e-04	GO:0006796	phosphate metabolic process
1.19	4.16e-04	GO:0051252	regulation of RNA metabolic process
1.45	5.00e-04	GO:0010648	negative regulation of cell communication
1.25	5.59e-04	GO:0051239	regulation of multicellular organismal process
1.18	6.53e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.44	7.34e-04	GO:0023057	negative regulation of signaling
1.13	8.23e-04	GO:0051716	cellular response to stimulus
1.31	8.46e-04	GO:0008219	cell death
1.31	9.29e-04	GO:0016265	death
1.88	1.10e-03	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
1.37	1.15e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12	1.17e-03	GO:0044260	cellular macromolecule metabolic process
1.56	1.19e-03	GO:0001568	blood vessel development
1.51	1.27e-03	GO:0060284	regulation of cell development
1.26	1.37e-03	GO:0031325	positive regulation of cellular metabolic process
1.39	1.49e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.54	1.54e-03	GO:0035295	tube development
1.38	1.62e-03	GO:0051253	negative regulation of RNA metabolic process
1.18	1.64e-03	GO:0006355	regulation of transcription, DNA-dependent
1.39	1.68e-03	GO:0006935	chemotaxis
1.39	1.68e-03	GO:0042330	taxis
1.32	1.84e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.45	1.98e-03	GO:0007264	small GTPase mediated signal transduction
1.32	1.98e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.36	2.04e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
2.40	2.11e-03	GO:0030509	BMP signaling pathway
1.44	2.32e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.82	2.35e-03	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.25	2.50e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.73	2.67e-03	GO:0016311	dephosphorylation
1.36	3.43e-03	GO:0042060	wound healing
1.50	3.72e-03	GO:0048729	tissue morphogenesis
1.31	3.78e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53	4.56e-03	GO:0016567	protein ubiquitination
1.38	4.82e-03	GO:0007417	central nervous system development
1.24	5.02e-03	GO:0009893	positive regulation of metabolic process
1.37	5.08e-03	GO:0010942	positive regulation of cell death
1.40	5.62e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.29	6.80e-03	GO:0051128	regulation of cellular component organization
1.31	7.68e-03	GO:0012501	programmed cell death
1.26	8.32e-03	GO:0032268	regulation of cellular protein metabolic process
1.28	8.33e-03	GO:0009891	positive regulation of biosynthetic process
1.29	8.49e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.25	9.56e-03	GO:0010941	regulation of cell death
1.37	1.04e-02	GO:0043068	positive regulation of programmed cell death
1.31	1.13e-02	GO:0006915	apoptosis
1.40	1.52e-02	GO:0016477	cell migration
1.25	1.61e-02	GO:0043067	regulation of programmed cell death
1.36	1.72e-02	GO:0043065	positive regulation of apoptosis
1.24	1.87e-02	GO:0051246	regulation of protein metabolic process
1.25	1.98e-02	GO:0042981	regulation of apoptosis
1.70	2.04e-02	GO:0006470	protein dephosphorylation
1.94	2.12e-02	GO:0007173	epidermal growth factor receptor signaling pathway
1.30	2.13e-02	GO:0009790	embryo development
1.18	2.17e-02	GO:0007166	cell surface receptor linked signaling pathway
1.28	2.18e-02	GO:0031399	regulation of protein modification process
1.47	2.40e-02	GO:0051270	regulation of cellular component movement
1.34	2.48e-02	GO:0006928	cellular component movement
1.49	2.55e-02	GO:0045596	negative regulation of cell differentiation
1.34	2.66e-02	GO:0023056	positive regulation of signaling
1.45	2.75e-02	GO:0022603	regulation of anatomical structure morphogenesis
1.47	3.01e-02	GO:0032446	protein modification by small protein conjugation
1.10	3.09e-02	GO:0043170	macromolecule metabolic process
1.74	3.24e-02	GO:0035023	regulation of Rho protein signal transduction
1.77	3.52e-02	GO:0010720	positive regulation of cell development
1.51	3.99e-02	GO:0007507	heart development
1.34	4.29e-02	GO:0010647	positive regulation of cell communication
1.37	4.67e-02	GO:0008285	negative regulation of cell proliferation
1.48	4.72e-02	GO:2000145	regulation of cell motility
1.48	4.76e-02	GO:0030334	regulation of cell migration
1.72	4.79e-02	GO:0006469	negative regulation of protein kinase activity
1.42	4.87e-02	GO:0007389	pattern specification process
1.40	4.87e-02	GO:0048598	embryonic morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	6.66e-24	GO:0005622	intracellular
1.10	7.14e-24	GO:0044424	intracellular part
1.12	8.62e-16	GO:0005737	cytoplasm
1.10	6.17e-13	GO:0043226	organelle
1.10	7.62e-13	GO:0043229	intracellular organelle
1.10	3.29e-10	GO:0043227	membrane-bounded organelle
1.10	4.90e-10	GO:0043231	intracellular membrane-bounded organelle
1.93	7.53e-08	GO:0005912	adherens junction
1.83	1.11e-07	GO:0031252	cell leading edge
1.12	2.03e-07	GO:0044444	cytoplasmic part
1.12	3.28e-07	GO:0005634	nucleus
1.83	6.42e-07	GO:0070161	anchoring junction
1.21	2.44e-06	GO:0005829	cytosol
1.03	9.61e-06	GO:0044464	cell part
1.03	1.04e-05	GO:0005623	cell
1.34	5.67e-04	GO:0030054	cell junction
1.91	1.31e-03	GO:0030027	lamellipodium
1.80	1.31e-03	GO:0030055	cell-substrate junction
1.25	2.16e-03	GO:0005794	Golgi apparatus
1.81	2.51e-03	GO:0005925	focal adhesion
1.76	5.49e-03	GO:0005924	cell-substrate adherens junction
1.92	1.64e-02	GO:0031256	leading edge membrane
1.76	2.26e-02	GO:0001726	ruffle
1.41	2.48e-02	GO:0015629	actin cytoskeleton
1.17	4.11e-02	GO:0005856	cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.08	7.06e-14	GO:0005488	binding
1.12	1.91e-11	GO:0005515	protein binding
1.15	4.79e-07	GO:0046872	metal ion binding
1.50	5.10e-07	GO:0060589	nucleoside-triphosphatase regulator activity
1.50	9.73e-07	GO:0030695	GTPase regulator activity
1.15	1.08e-06	GO:0043167	ion binding
1.15	1.21e-06	GO:0043169	cation binding
1.57	2.10e-06	GO:0042578	phosphoric ester hydrolase activity
1.44	2.98e-06	GO:0008092	cytoskeletal protein binding
1.29	5.75e-05	GO:0030528	transcription regulator activity
1.59	9.21e-05	GO:0016791	phosphatase activity
1.53	1.76e-04	GO:0005083	small GTPase regulator activity
2.40	1.94e-04	GO:0046332	SMAD binding
1.33	2.17e-04	GO:0019899	enzyme binding
1.52	2.20e-04	GO:0008134	transcription factor binding
1.28	2.28e-04	GO:0001071	nucleic acid binding transcription factor activity
1.28	2.28e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.71	2.57e-04	GO:0005085	guanyl-nucleotide exchange factor activity
1.49	4.07e-04	GO:0003779	actin binding
1.69	6.00e-04	GO:0004721	phosphoprotein phosphatase activity
1.58	6.93e-04	GO:0004842	ubiquitin-protein ligase activity
1.48	7.62e-04	GO:0016563	transcription activator activity
1.51	1.53e-03	GO:0016881	acid-amino acid ligase activity
1.78	1.63e-03	GO:0051020	GTPase binding
1.47	2.14e-03	GO:0016564	transcription repressor activity
1.57	2.66e-03	GO:0000975	regulatory region DNA binding
1.57	2.66e-03	GO:0001067	regulatory region nucleic acid binding
1.57	2.66e-03	GO:0044212	transcription regulatory region DNA binding
1.52	3.61e-03	GO:0019787	small conjugating protein ligase activity
1.46	3.99e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.17	4.76e-03	GO:0008270	zinc ion binding
1.84	4.77e-03	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.56	6.55e-03	GO:0010843	promoter binding
1.15	8.73e-03	GO:0046914	transition metal ion binding
1.89	1.67e-02	GO:0005089	Rho guanyl-nucleotide exchange factor activity
1.74	2.33e-02	GO:0031267	small GTPase binding
1.76	3.28e-02	GO:0017016	Ras GTPase binding
1.33	4.92e-02	GO:0019904	protein domain specific binding