Motif ID: PAX5.p2

Z-value: 2.943


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.391.4e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_61742111 8.083 NM_020828
 ZFP28
zinc finger protein 28 homolog (mouse)
chr13_-_43351825 5.530 NM_144974
 CCDC122
coiled-coil domain containing 122
chr4_-_7991992 5.260 NM_001134647
NM_198595
 AFAP1

actin filament associated protein 1

chr2_+_235525355 4.954 NM_014521
 SH3BP4
SH3-domain binding protein 4
chr10_-_30064600 4.647 NM_003174
 SVIL
supervillin
chr13_+_43351968 4.241 NM_153218
 C13orf31
chromosome 13 open reading frame 31
chrX_+_43399101 4.134 MAOA
monoamine oxidase A
chr10_-_105604942 4.099 NM_014631
 SH3PXD2A
SH3 and PX domains 2A
chr1_+_15957832 3.988 NM_017556
 FBLIM1
filamin binding LIM protein 1
chr5_+_96023926 3.712 CAST
calpastatin
chr12_+_13044604 3.671 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr17_-_78199384 3.635 NM_019613
 WDR45L
WDR45-like
chr3_-_133923992 3.597 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr21_+_32706615 3.470 NM_058187
 C21orf63
chromosome 21 open reading frame 63
chr13_-_105985313 3.338 NM_004093
 EFNB2
ephrin-B2
chr1_-_223907283 3.325 NM_001008493
NM_018212
 ENAH

enabled homolog (Drosophila)

chr4_-_177950658 3.273 NM_005429
 VEGFC
vascular endothelial growth factor C
chr3_-_133923906 3.262 NM_153240
 NPHP3
nephronophthisis 3 (adolescent)
chr3_+_133923758 3.231 NCRNA00119
non-protein coding RNA 119
chr2_+_238265617 3.166 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 136 entries
enrichment   p-value GO term description
1.82 3.62e-02 GO:0050770 regulation of axonogenesis
1.81 1.21e-05 GO:0006470 protein dephosphorylation
1.81 3.89e-03 GO:0006665 sphingolipid metabolic process
1.79 2.32e-03 GO:0006643 membrane lipid metabolic process
1.73 6.70e-05 GO:0016311 dephosphorylation
1.72 6.20e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.71 9.39e-04 GO:0022604 regulation of cell morphogenesis
1.58 2.02e-02 GO:0034330 cell junction organization
1.55 5.29e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.54 3.34e-02 GO:0051272 positive regulation of cellular component movement
1.50 6.14e-05 GO:0060284 regulation of cell development
1.49 9.19e-07 GO:0009968 negative regulation of signal transduction
1.49 3.42e-06 GO:0007264 small GTPase mediated signal transduction
1.49 2.70e-04 GO:0051270 regulation of cellular component movement
1.49 1.37e-03 GO:0030334 regulation of cell migration
1.49 1.55e-03 GO:2000145 regulation of cell motility
1.46 1.54e-03 GO:0040012 regulation of locomotion
1.46 4.04e-03 GO:0035295 tube development
1.46 1.90e-02 GO:0001558 regulation of cell growth
1.43 1.26e-07 GO:0000902 cell morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
2.03 1.66e-08 GO:0005925 focal adhesion
1.99 2.75e-08 GO:0005924 cell-substrate adherens junction
1.98 3.51e-12 GO:0005912 adherens junction
1.98 2.36e-08 GO:0030055 cell-substrate junction
1.87 2.23e-10 GO:0070161 anchoring junction
1.76 1.44e-03 GO:0001726 ruffle
1.73 3.96e-03 GO:0016327 apicolateral plasma membrane
1.72 7.97e-03 GO:0043296 apical junction complex
1.67 2.55e-06 GO:0031252 cell leading edge
1.66 6.42e-03 GO:0019898 extrinsic to membrane
1.48 7.27e-04 GO:0016323 basolateral plasma membrane
1.45 1.40e-02 GO:0005911 cell-cell junction
1.39 4.38e-03 GO:0015629 actin cytoskeleton
1.37 6.92e-05 GO:0000139 Golgi membrane
1.35 1.69e-05 GO:0044431 Golgi apparatus part
1.34 2.11e-05 GO:0030054 cell junction
1.33 2.34e-09 GO:0005794 Golgi apparatus
1.32 3.78e-02 GO:0048471 perinuclear region of cytoplasm
1.29 3.49e-04 GO:0015630 microtubule cytoskeleton
1.29 2.16e-02 GO:0005768 endosome

Gene overrepresentation in function category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
3.14 4.83e-03 GO:0030275 LRR domain binding
1.73 2.39e-03 GO:0004725 protein tyrosine phosphatase activity
1.70 7.83e-06 GO:0004721 phosphoprotein phosphatase activity
1.63 1.59e-02 GO:0017124 SH3 domain binding
1.57 3.38e-02 GO:0035091 phosphatidylinositol binding
1.49 5.65e-04 GO:0016791 phosphatase activity
1.46 4.04e-07 GO:0019904 protein domain specific binding
1.41 4.93e-04 GO:0042578 phosphoric ester hydrolase activity
1.38 3.60e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.37 1.38e-04 GO:0030695 GTPase regulator activity
1.35 1.45e-03 GO:0004674 protein serine/threonine kinase activity
1.35 3.97e-02 GO:0016563 transcription activator activity
1.31 2.52e-03 GO:0008092 cytoskeletal protein binding
1.29 3.47e-06 GO:0030234 enzyme regulator activity
1.27 8.69e-04 GO:0019899 enzyme binding
1.24 1.52e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.24 1.63e-02 GO:0042802 identical protein binding
1.23 1.15e-03 GO:0030528 transcription regulator activity
1.23 1.39e-02 GO:0016301 kinase activity
1.23 4.88e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor