Motif ID: NFKB1_REL_RELA.p2

Z-value: 4.389


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFKB1chr4_+_1036418540.721.6e-03Click!
RELchr2_+_609622790.683.5e-03Click!
RELAchr11_-_651870030.683.8e-03Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_104145421 10.283 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_-_6542012 7.956 CD70
CD70 molecule
chr2_+_219453487 7.433 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr10_+_104144218 6.628 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr20_-_4743768 6.023 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr19_+_4180494 5.616 NM_005755
EBI3
Epstein-Barr virus induced 3
chr2_-_231498184 5.469 NM_005683
GPR55
G protein-coupled receptor 55
chr1_-_207891264 5.343 NM_001017402
LAMB3
laminin, beta 3
chr8_-_70909754 5.231 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr2_-_162883062 4.947 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr19_+_3087026 4.904 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr6_+_116798791 4.865 NM_013352
DSE
dermatan sulfate epimerase
chr17_+_35277942 4.761 NM_198844
NM_199321
ZPBP2

zona pellucida binding protein 2

chr1_-_207892420 4.548 NM_000228
LAMB3
laminin, beta 3
chr11_+_101693403 4.346 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr12_-_55790355 4.342 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_-_24386324 4.304 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr14_-_95250155 4.177 NM_001098725
NM_021966
TCL1A

T-cell leukemia/lymphoma 1A

chr6_+_32713160 4.081 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_-_6542082 4.057 CD70
CD70 molecule
chr6_+_30958672 4.035 DDR1
discoidin domain receptor tyrosine kinase 1
chr22_-_35875890 4.008 NM_000878
IL2RB
interleukin 2 receptor, beta
chr10_+_12431477 3.999 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr5_+_10617431 3.968 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr3_-_113334657 3.965 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr16_+_49333513 3.857 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr5_-_149772469 3.789 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr3_-_58175437 3.770 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr16_+_49333461 3.769 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr5_-_149772528 3.754


chr17_+_22823151 3.649 NM_014238
KSR1
kinase suppressor of ras 1
chr11_+_120828058 3.590 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_126094388 3.570 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr22_-_42539399 3.485 NM_022785
NM_198856
EFCAB6

EF-hand calcium binding domain 6

chr7_-_44985084 3.483 MYO1G
myosin IG
chr20_-_24986501 3.458 ACSS1
acyl-CoA synthetase short-chain family member 1
chr15_+_83724743 3.456 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chrX_-_30505804 3.418 NM_025159
CXorf21
chromosome X open reading frame 21
chr6_-_31432934 3.414 HLA-B
major histocompatibility complex, class I, B
chr22_-_35970133 3.363 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_+_123279439 3.356 NM_006889
CD86
CD86 molecule
chr8_-_11361594 3.330 NM_053279
FAM167A
family with sequence similarity 167, member A
chr9_+_126094067 3.314 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr6_+_14225932 3.292 CD83
CD83 molecule
chr19_+_47073029 3.264 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr8_-_11096257 3.262 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr16_+_49288550 3.235 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr20_+_44180296 3.222 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr14_+_102313585 3.170 TRAF3
TNF receptor-associated factor 3
chr22_-_35970230 3.164 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_48976852 3.157 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_12431714 3.135 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr9_-_135334003 3.130 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr11_+_66580884 3.122 RHOD
ras homolog gene family, member D
chr11_-_64327197 3.088 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr3_-_48607596 2.985 NM_000094
COL7A1
collagen, type VII, alpha 1
chr8_-_95343716 2.984 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr17_-_16816113 2.978 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr11_+_66580861 2.946 NM_014578
RHOD
ras homolog gene family, member D
chr10_-_134940315 2.935 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_-_208046011 2.838 NM_006147
IRF6
interferon regulatory factor 6
chr1_-_21489235 2.826 NM_001113349
ECE1
endothelin converting enzyme 1
chr19_-_4289750 2.820 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr14_+_75058591 2.818 BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_102313566 2.783 NM_003300
NM_145725
NM_145726
TRAF3


TNF receptor-associated factor 3


chr16_+_84490267 2.782 NM_002163
IRF8
interferon regulatory factor 8
chr4_-_119493322 2.780 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr12_+_6925997 2.779 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_-_7672978 2.772 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr19_-_56214765 2.760 NM_145888
KLK10
kallikrein-related peptidase 10
chr11_+_120828275 2.722 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr15_+_79376295 2.721 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr3_-_13089547 2.685 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr5_+_110587546 2.679 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr1_+_26744929 2.643 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_-_149772563 2.624 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr14_+_75058518 2.610 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr8_-_139995417 2.608 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr17_+_7402315 2.605 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr1_+_40193424 2.550 MFSD2A
major facilitator superfamily domain containing 2A
chr6_-_31432954 2.515 NM_005514
HLA-B
major histocompatibility complex, class I, B
chr17_+_8865547 2.488 NM_004822
NTN1
netrin 1
chr19_-_48977247 2.472 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr7_-_44985202 2.470 NM_033054
MYO1G
myosin IG
chr19_+_50196526 2.431 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr1_-_85235210 2.427 NM_153259
MCOLN2
mucolipin 2
chr1_+_26744893 2.425 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_-_6542136 2.390 NM_001252
CD70
CD70 molecule
chr7_+_68702516 2.381 AUTS2
autism susceptibility candidate 2
chr19_-_4782711 2.363 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr19_+_5082230 2.320 KDM4B
lysine (K)-specific demethylase 4B
chr6_-_31432877 2.312 HLA-B
major histocompatibility complex, class I, B
chr12_+_111980044 2.309 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr3_-_52065130 2.303 NM_001947
DUSP7
dual specificity phosphatase 7
chr17_+_62804036 2.289 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_+_208102860 2.276 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr22_-_32646325 2.271 NM_004737
NM_133642
LARGE

like-glycosyltransferase

chr20_+_54637714 2.255 NM_003222
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr1_-_180840016 2.244 NM_002928
RGS16
regulator of G-protein signaling 16
chr12_+_6926014 2.232 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr7_-_44985175 2.193 MYO1G
myosin IG
chr4_-_147079018 2.185 NM_178835
ZNF827
zinc finger protein 827
chr1_+_6767968 2.169 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr7_-_24763556 2.144 DFNA5
deafness, autosomal dominant 5
chr3_-_150858274 2.143 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr17_+_62803824 2.141 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_-_58877276 2.130 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr1_-_184916044 2.107 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_116799548 2.106 LOC100287467
hypothetical LOC100287467
chr6_+_106640903 2.106 PRDM1
PR domain containing 1, with ZNF domain
chr5_+_56505412 2.091 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr20_+_44180355 2.081 CD40
CD40 molecule, TNF receptor superfamily member 5
chr12_-_28016182 2.080 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr6_+_31647854 2.070 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr6_-_132764257 2.041 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr5_+_56505608 2.018 GPBP1
GC-rich promoter binding protein 1
chr7_+_18515440 2.017 HDAC9
histone deacetylase 9
chr17_+_4922445 2.014 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr2_-_74522513 2.007 RTKN
rhotekin
chrX_+_12795111 2.002 NM_016562
TLR7
toll-like receptor 7
chr15_+_57517564 1.994 NM_152450
FAM81A
family with sequence similarity 81, member A
chr16_-_21221872 1.994 NM_001014444
NM_001888
CRYM

crystallin, mu

chrX_+_78087484 1.989 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr7_+_18515488 1.986 HDAC9
histone deacetylase 9
chr17_-_6400470 1.977 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr6_-_32919751 1.968 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr15_+_80434362 1.949 UBE2Q2P2
ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr19_+_40632456 1.948 NM_005306
FFAR2
free fatty acid receptor 2
chr9_+_4480193 1.946 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr3_+_113200696 1.903 NM_001008273
TAGLN3
transgelin 3
chr17_-_35506493 1.899 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr18_+_22060383 1.896 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_+_152644668 1.889 IL6R
interleukin 6 receptor
chr7_+_100584397 1.889 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr4_-_147079410 1.879


chr6_+_29799095 1.877 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr19_+_55614006 1.871 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr17_+_19999784 1.865 NM_001033554
NM_001033555
SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr16_+_55580910 1.856 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr22_+_38720881 1.856 NM_138435
FAM83F
family with sequence similarity 83, member F
chr6_+_31648071 1.853 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr6_+_106640881 1.850 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr4_+_142777172 1.846 NM_000585
NM_172174
IL15

interleukin 15

chr2_-_74522534 1.839 RTKN
rhotekin
chr4_+_107036076 1.835 NPNT
nephronectin
chr5_+_167651063 1.833 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr14_-_64040072 1.829 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr11_+_61352348 1.822 FADS2
fatty acid desaturase 2
chr2_-_74522563 1.821 NM_001015055
RTKN
rhotekin
chr1_-_159275334 1.820 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr19_+_1018536 1.804 HMHA1
histocompatibility (minor) HA-1
chr11_-_76800525 1.787 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr2_-_235070431 1.769 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr6_+_32919873 1.760


chr5_-_54866126 1.757 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr19_-_17819814 1.744 NM_000215
JAK3
Janus kinase 3
chr19_+_17499064 1.741 FAM129C
family with sequence similarity 129, member C
chr19_+_11936868 1.733 NM_001012753
ZNF763
zinc finger protein 763
chr11_-_3818759 1.721 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr19_+_49943773 1.710 NM_005178
BCL3
B-cell CLL/lymphoma 3
chr20_-_57015547 1.701 CTSZ
cathepsin Z
chr10_-_105427898 1.694 SH3PXD2A
SH3 and PX domains 2A
chr1_+_35104120 1.690


chr19_+_43502301 1.686 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr19_+_54786723 1.681 NM_020719
PRR12
proline rich 12
chr19_-_17819773 1.681 JAK3
Janus kinase 3
chr18_-_26996742 1.676 NM_004948
NM_024421
DSC1

desmocollin 1

chr6_+_29799182 1.672 HLA-F
major histocompatibility complex, class I, F
chr5_+_177473071 1.665 NM_015111
N4BP3
NEDD4 binding protein 3
chr6_+_29963328 1.665 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr7_-_24763841 1.664 DFNA5
deafness, autosomal dominant 5
chr1_-_27834210 1.651 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr3_+_53170254 1.650 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr22_+_44828338 1.641


chr1_-_207892296 1.640 NM_001127641
LAMB3
laminin, beta 3
chr11_-_3818713 1.638 RHOG
ras homolog gene family, member G (rho G)
chr7_+_114349376 1.631 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr5_-_131854325 1.629 NM_002198
IRF1
interferon regulatory factor 1
chr1_+_26896519 1.628 ARID1A
AT rich interactive domain 1A (SWI-like)
chr19_+_45915122 1.619 ITPKC
inositol 1,4,5-trisphosphate 3-kinase C
chr12_+_12761085 1.610 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr8_-_95343696 1.603 GEM
GTP binding protein overexpressed in skeletal muscle
chr8_+_54955962 1.602 NM_003702
RGS20
regulator of G-protein signaling 20
chr15_-_72804763 1.597 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr11_-_133332089 1.596 NM_014987
IGSF9B
immunoglobulin superfamily, member 9B
chr11_-_117521344 1.594 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr19_+_8180179 1.591 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr20_+_58146916 1.588 LOC284757
hypothetical protein LOC284757
chr19_-_55091942 1.586 NM_152899
IL4I1
interleukin 4 induced 1
chrX_-_83329562 1.576 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr1_-_93199586 1.559 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr19_+_43502591 1.559 KCNK6
potassium channel, subfamily K, member 6
chr3_+_120496180 1.558 ARHGAP31
Rho GTPase activating protein 31
chr19_+_45389356 1.549 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr1_-_183210155 1.544 FAM129A
family with sequence similarity 129, member A
chr2_+_208102937 1.520 CREB1
cAMP responsive element binding protein 1
chr6_+_31538934 1.519 NM_006674
HCP5
HLA complex P5
chr1_-_159275357 1.516 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr1_-_181826633 1.515 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr6_+_30018265 1.515 HLA-A
major histocompatibility complex, class I, A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 1.21e-08 GO:0002682 regulation of immune system process
1.81 4.93e-08 GO:0006955 immune response
1.31 3.21e-06 GO:0007165 signal transduction
1.54 6.06e-06 GO:0002376 immune system process
2.40 6.77e-06 GO:0051249 regulation of lymphocyte activation
1.28 9.19e-06 GO:0023052 signaling
1.94 1.34e-05 GO:0002684 positive regulation of immune system process
2.10 1.76e-05 GO:0031347 regulation of defense response
2.27 2.91e-05 GO:0002694 regulation of leukocyte activation
2.48 4.37e-05 GO:0045088 regulation of innate immune response
1.32 5.87e-05 GO:0048518 positive regulation of biological process
1.34 9.16e-05 GO:0048522 positive regulation of cellular process
2.18 1.17e-04 GO:0050865 regulation of cell activation
2.44 1.60e-04 GO:0051251 positive regulation of lymphocyte activation
1.84 2.43e-04 GO:0050776 regulation of immune response
1.92 3.50e-04 GO:0045087 innate immune response
2.45 5.88e-04 GO:0002697 regulation of immune effector process
1.23 5.99e-04 GO:0051716 cellular response to stimulus
1.51 1.09e-03 GO:0006793 phosphorus metabolic process
1.51 1.09e-03 GO:0006796 phosphate metabolic process
2.27 1.26e-03 GO:0002696 positive regulation of leukocyte activation
1.36 1.81e-03 GO:0006464 protein modification process
2.29 1.91e-03 GO:0050863 regulation of T cell activation
2.23 2.04e-03 GO:0050867 positive regulation of cell activation
4.40 2.14e-03 GO:0060443 mammary gland morphogenesis
1.72 2.21e-03 GO:0080134 regulation of response to stress
3.11 2.52e-03 GO:0034130 toll-like receptor 1 signaling pathway
3.11 2.52e-03 GO:0034134 toll-like receptor 2 signaling pathway
2.87 2.55e-03 GO:0002224 toll-like receptor signaling pathway
1.35 2.69e-03 GO:0048583 regulation of response to stimulus
1.58 2.92e-03 GO:0006468 protein phosphorylation
2.99 3.09e-03 GO:0002699 positive regulation of immune effector process
1.41 3.26e-03 GO:0035556 intracellular signal transduction
1.55 3.54e-03 GO:0048584 positive regulation of response to stimulus
2.76 3.62e-03 GO:0002758 innate immune response-activating signal transduction
2.95 4.01e-03 GO:0034142 toll-like receptor 4 signaling pathway
2.26 5.51e-03 GO:0031349 positive regulation of defense response
2.70 5.66e-03 GO:0002218 activation of innate immune response
2.74 6.52e-03 GO:0002221 pattern recognition receptor signaling pathway
1.52 6.62e-03 GO:0016310 phosphorylation
1.33 6.82e-03 GO:0043412 macromolecule modification
2.94 7.32e-03 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.75 8.72e-03 GO:0007243 intracellular protein kinase cascade
1.75 8.72e-03 GO:0023014 signal transduction via phosphorylation event
2.42 1.14e-02 GO:0045089 positive regulation of innate immune response
2.33 1.31e-02 GO:0050870 positive regulation of T cell activation
2.82 1.53e-02 GO:0008063 Toll signaling pathway
5.13 1.54e-02 GO:0060330 regulation of response to interferon-gamma
5.13 1.54e-02 GO:0060334 regulation of interferon-gamma-mediated signaling pathway
1.14 1.69e-02 GO:0050794 regulation of cellular process
2.12 1.99e-02 GO:0002764 immune response-regulating signaling pathway
1.41 2.06e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.15 2.18e-02 GO:0050896 response to stimulus
1.95 2.35e-02 GO:0045321 leukocyte activation
2.11 2.86e-02 GO:0002757 immune response-activating signal transduction
1.43 2.91e-02 GO:0010941 regulation of cell death
1.43 3.14e-02 GO:0043067 regulation of programmed cell death
1.43 3.17e-02 GO:0042981 regulation of apoptosis
1.63 3.42e-02 GO:0043068 positive regulation of programmed cell death
2.94 3.48e-02 GO:0034138 toll-like receptor 3 signaling pathway
1.62 3.52e-02 GO:0010942 positive regulation of cell death
2.68 3.81e-02 GO:0034341 response to interferon-gamma
2.44 4.24e-02 GO:0070663 regulation of leukocyte proliferation
1.84 4.62e-02 GO:0050778 positive regulation of immune response
1.86 4.71e-02 GO:0001817 regulation of cytokine production
4.64 4.85e-02 GO:0060603 mammary gland duct morphogenesis
1.62 4.91e-02 GO:0043065 positive regulation of apoptosis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
9.75 5.14e-03 GO:0033256 I-kappaB/NF-kappaB complex
1.25 3.42e-02 GO:0005829 cytosol
1.24 4.47e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 1.74e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.64 1.78e-02 GO:0004674 protein serine/threonine kinase activity
1.42 2.70e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.45 3.47e-02 GO:0016301 kinase activity
1.50 4.62e-02 GO:0004672 protein kinase activity