Motif ID: POU1F1.p2

Z-value: 1.181


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_874083010.401.2e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_105511615 1.792 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr17_-_36232366 1.442 NM_000421
KRT10
keratin 10
chr13_-_45654292 1.396 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_59564323 1.360 NM_173801
PLAC1L
placenta-specific 1-like
chr13_-_45654296 1.215 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_14840506 1.202 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_33149244 1.125 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr13_-_45654327 1.058 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_143351536 1.045 NM_001032998
NM_003937
KYNU

kynureninase

chr3_+_123779122 1.015 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr1_-_1701313 0.973 NM_001198994
NADK
NAD kinase
chr5_-_41249270 0.945 NM_000065
C6
complement component 6
chr19_+_47073029 0.945 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr6_+_132000134 0.945 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_+_45174446 0.932 NM_152719
SPERT
spermatid associated
chr4_+_88076418 0.902


chr5_-_78318112 0.902 NM_000046
ARSB
arylsulfatase B
chr6_+_26359805 0.814 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr3_-_122862447 0.805 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_+_188197029 0.784



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
9.99 6.94e-04 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
4.02 4.21e-22 GO:0007608 sensory perception of smell
3.94 3.54e-02 GO:0002449 lymphocyte mediated immunity
3.69 2.29e-20 GO:0007606 sensory perception of chemical stimulus
2.59 1.47e-02 GO:0002253 activation of immune response
2.38 9.91e-11 GO:0007600 sensory perception
2.35 2.19e-02 GO:0050778 positive regulation of immune response
2.16 3.93e-03 GO:0050776 regulation of immune response
1.97 2.51e-04 GO:0006955 immune response
1.86 1.70e-03 GO:0006952 defense response
1.80 3.32e-06 GO:0050877 neurological system process
1.76 1.92e-07 GO:0003008 system process
1.62 8.68e-03 GO:0002376 immune system process
1.35 3.51e-09 GO:0050896 response to stimulus
1.27 1.99e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
12.13 1.51e-05 GO:0042613 MHC class II protein complex
5.97 3.19e-03 GO:0042611 MHC protein complex
1.42 3.03e-08 GO:0071944 cell periphery
1.42 3.09e-08 GO:0005886 plasma membrane
1.38 3.00e-02 GO:0005576 extracellular region
1.28 6.16e-05 GO:0016021 integral to membrane
1.27 5.95e-05 GO:0031224 intrinsic to membrane
1.22 3.85e-04 GO:0044425 membrane part
1.16 7.90e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.78 3.56e-02 GO:0003823 antigen binding
4.21 4.82e-24 GO:0004984 olfactory receptor activity
2.51 4.70e-14 GO:0004930 G-protein coupled receptor activity
2.19 1.72e-14 GO:0004888 transmembrane receptor activity
1.86 8.07e-11 GO:0004872 receptor activity
1.70 4.43e-09 GO:0004871 signal transducer activity
1.70 4.43e-09 GO:0060089 molecular transducer activity