Motif ID: POU1F1.p2

Z-value: 1.181


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_874083010.401.2e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_105511615 1.792 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr17_-_36232366 1.442 NM_000421
KRT10
keratin 10
chr13_-_45654292 1.396 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_59564323 1.360 NM_173801
PLAC1L
placenta-specific 1-like
chr13_-_45654296 1.215 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_-_14840506 1.202 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_33149244 1.125 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr13_-_45654327 1.058 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_143351536 1.045 NM_001032998
NM_003937
KYNU

kynureninase

chr3_+_123779122 1.015 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr1_-_1701313 0.973 NM_001198994
NADK
NAD kinase
chr5_-_41249270 0.945 NM_000065
C6
complement component 6
chr19_+_47073029 0.945 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr6_+_132000134 0.945 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_+_45174446 0.932 NM_152719
SPERT
spermatid associated
chr4_+_88076418 0.902


chr5_-_78318112 0.902 NM_000046
ARSB
arylsulfatase B
chr6_+_26359805 0.814 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr3_-_122862447 0.805 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_+_188197029 0.784


chr2_+_37282516 0.776 LOC100505876
hypothetical LOC100505876
chr6_+_167456230 0.765 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr21_+_41663853 0.760 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr19_-_53081326 0.736 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr1_+_12046020 0.715 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chrX_-_30505804 0.709 NM_025159
CXorf21
chromosome X open reading frame 21
chr12_-_101835183 0.693 PAH
phenylalanine hydroxylase
chr4_+_73123712 0.682 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr15_-_32398220 0.666 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr17_-_38385511 0.664 NM_025267
AARSD1
alanyl-tRNA synthetase domain containing 1
chr7_+_143043871 0.664 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr3_-_122862391 0.653 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_-_53444733 0.639 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr9_-_70780574 0.638


chr12_+_53534565 0.630 NM_058173
MUCL1
mucin-like 1
chr3_+_152970904 0.622 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr6_-_41276901 0.617 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chr17_+_54587882 0.614 PRR11
proline rich 11
chr8_-_17797127 0.610 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr6_+_31647854 0.606 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr1_-_159546348 0.605 NM_000530
MPZ
myelin protein zero
chr21_-_31995972 0.602 SCAF4
SR-related CTD-associated factor 4
chr6_+_64344307 0.600 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr21_-_42659671 0.585 NM_003225
TFF1
trefoil factor 1
chr15_+_64481270 0.583 MAP2K1
mitogen-activated protein kinase kinase 1
chr2_-_88208650 0.581 NM_001443
FABP1
fatty acid binding protein 1, liver
chr8_+_82807218 0.568 NM_152284
CHMP4C
chromatin modifying protein 4C
chr16_-_28528149 0.564 NM_177530
NM_177534
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr7_-_44985175 0.562 MYO1G
myosin IG
chr7_+_137411717 0.557 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr3_-_186752952 0.547 NM_139248
LIPH
lipase, member H
chr1_-_158815895 0.547 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr2_-_6924092 0.539 CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr7_-_44985084 0.536 MYO1G
myosin IG
chr1_-_41399632 0.530 NM_001031694
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr7_-_44985202 0.530 NM_033054
MYO1G
myosin IG
chr18_-_3001944 0.498 NM_014646
LPIN2
lipin 2
chr6_-_149847809 0.496 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr5_-_75954807 0.496 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr4_-_70115037 0.473 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr4_+_141484046 0.473 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr2_+_24660849 0.471 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr17_-_36418869 0.471 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr12_+_43972732 0.462 NM_001142678
ANO6
anoctamin 6
chr22_-_25205376 0.461 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr4_-_110942783 0.459 NM_000204
CFI
complement factor I
chr16_-_28528780 0.458 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr3_+_192413015 0.458 NM_198184
OSTN
osteocrin
chr9_+_130056513 0.456


chr9_+_124072947 0.447 NM_199177
MRRF
mitochondrial ribosome recycling factor
chr1_+_165565006 0.445 POU2F1
POU class 2 homeobox 1
chr4_+_95595419 0.444 PDLIM5
PDZ and LIM domain 5
chr6_+_32515596 0.443 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr1_+_13903936 0.438 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr6_-_76022565 0.436 TMEM30A
transmembrane protein 30A
chr2_+_68445936 0.425 PLEK
pleckstrin
chr6_-_33028790 0.424 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr2_-_230798687 0.422 NM_001185015
SP110
SP110 nuclear body protein
chr1_+_166516901 0.419 NM_005149
TBX19
T-box 19
chr20_+_71230 0.419 NM_030931
DEFB126
defensin, beta 126
chr17_-_64649608 0.419 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr6_-_149847718 0.416 ZC3H12D
zinc finger CCCH-type containing 12D
chr17_-_31281398 0.415 NM_001163122
NM_001163124
NM_001163125
NM_001163130
RDM1



RAD52 motif 1



chr2_-_174475528 0.414


chr1_-_100416358 0.411 NM_144620
LRRC39
leucine rich repeat containing 39
chr5_+_137701122 0.404 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr11_+_5862076 0.403 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr4_-_140280031 0.399 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr16_+_14938800 0.397 NM_006985
NPIP
nuclear pore complex interacting protein
chr17_-_59437782 0.395 NM_000873
ICAM2
intercellular adhesion molecule 2
chr8_-_42742729 0.394 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr12_-_85756766 0.393 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_167822248 0.393 F5
coagulation factor V (proaccelerin, labile factor)
chr15_-_53349775 0.392 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chrX_-_23765377 0.387 RPL9
ribosomal protein L9
chr17_-_59817456 0.386 PECAM1
platelet/endothelial cell adhesion molecule
chr12_+_130004404 0.384 NM_198827
GPR133
G protein-coupled receptor 133
chr2_-_224974954 0.383 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr6_-_52736231 0.379 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr3_+_181803649 0.375 TTC14
tetratricopeptide repeat domain 14
chr7_+_77307382 0.374 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr12_-_8656705 0.371 NM_020661
AICDA
activation-induced cytidine deaminase
chr12_-_101835026 0.369 PAH
phenylalanine hydroxylase
chr13_-_40454360 0.368 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_-_7541974 0.366 NM_001037763
COL28A1
collagen, type XXVIII, alpha 1
chr1_-_158815850 0.364 CD84
CD84 molecule
chr8_-_38127489 0.356 NM_000349
STAR
steroidogenic acute regulatory protein
chr4_+_74520796 0.356 NM_001134
AFP
alpha-fetoprotein
chr2_+_201464884 0.355 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr3_-_113334657 0.351 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr4_-_71751070 0.348 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_+_156628929 0.348 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_89364273 0.347 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr5_+_68703036 0.341 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr21_-_32879617 0.341 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr11_+_123600553 0.340 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr7_+_106897737 0.339 NM_005295
GPR22
G protein-coupled receptor 22
chr1_-_246869181 0.338 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr11_+_93940121 0.333 NM_152431
PIWIL4
piwi-like 4 (Drosophila)
chrX_-_1291526 0.332 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr8_-_17811750 0.325 FGL1
fibrinogen-like 1
chr8_+_39890484 0.322 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr16_+_11966464 0.322 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr20_-_36191623 0.321 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr1_+_158603480 0.320 NM_005598
NHLH1
nescient helix loop helix 1
chr19_-_11355882 0.320 NM_000121
EPOR
erythropoietin receptor
chr4_+_71261066 0.319 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr11_-_102250876 0.316 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chrX_-_39921525 0.315 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr5_-_39238818 0.313 FYB
FYN binding protein
chr4_-_83566045 0.311


chr13_+_23742846 0.310 SPATA13
spermatogenesis associated 13
chr11_+_4976788 0.308 NM_001004755
OR51L1
olfactory receptor, family 51, subfamily L, member 1
chr9_-_99746923 0.308 NM_018437
HEMGN
hemogen
chr4_-_38710376 0.305 NM_024943
TMEM156
transmembrane protein 156
chr10_+_89107404 0.305 NM_001009610
FAM22A
FAM22D
family with sequence similarity 22, member A
family with sequence similarity 22, member D
chr5_-_78317444 0.305 NM_198709
ARSB
arylsulfatase B
chr15_+_32425357 0.303 NM_175741
C15orf55
chromosome 15 open reading frame 55
chr7_+_29486010 0.303 NM_001039936
CHN2
chimerin (chimaerin) 2
chr2_+_183290912 0.303 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr6_+_28217590 0.301 NM_006298
ZNF192
zinc finger protein 192
chr9_-_205892 0.299 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr17_+_30472710 0.297 NM_017559
FNDC8
fibronectin type III domain containing 8
chr17_-_59817575 0.295 PECAM1
platelet/endothelial cell adhesion molecule
chr4_-_151990061 0.291 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr6_-_109795925 0.287 CD164
CD164 molecule, sialomucin
chr3_+_143824955 0.287 NM_002670
PLS1
plastin 1
chr11_-_129322510 0.282 NM_199438
NM_199439
PRDM10

PR domain containing 10

chr4_+_74500748 0.282 ALB
albumin
chr14_-_19843969 0.280 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr19_+_6981593 0.277 NM_001136507
MBD3L5
methyl-CpG-binding domain protein 3-like 5-like
chr3_-_49826221 0.276 UBA7
ubiquitin-like modifier activating enzyme 7
chr10_+_91488704 0.276 KIF20B
kinesin family member 20B
chr2_+_102744921 0.275 NM_144632
TMEM182
transmembrane protein 182
chr13_-_40454188 0.275 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_143075560 0.275 NM_178230
NM_001143883
NM_001135789
PPIAL4A
PPIAL4G
PPIAL4B
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4G
peptidylprolyl isomerase A (cyclophilin A)-like 4B
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr1_+_178232379 0.275 CEP350
centrosomal protein 350kDa
chr10_+_5976354 0.273 NM_032807
FBXO18
F-box protein, helicase, 18
chr16_+_68156497 0.273 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NFAT5




nuclear factor of activated T-cells 5, tonicity-responsive




chr1_+_179269183 0.272 NM_001194999
NM_001195000
NM_001195035
NM_001531
MR1



major histocompatibility complex, class I-related



chr2_-_157890400 0.272 NM_020711
ERMN
ermin, ERM-like protein
chr6_+_44076281 0.268 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr22_+_38627129 0.267 GRAP2
GRB2-related adaptor protein 2
chr12_-_54150188 0.267 NM_001005499
OR6C70
olfactory receptor, family 6, subfamily C, member 70
chr14_+_38772870 0.266 NM_054024
MIA2
melanoma inhibitory activity 2
chr4_+_100714995 0.265 MTTP
microsomal triglyceride transfer protein
chr20_+_5935897 0.264 NM_001127458
CRLS1
cardiolipin synthase 1
chr8_-_82536312 0.264 NM_001080526
FABP9
fatty acid binding protein 9, testis
chr12_+_109956210 0.263 NM_015267
CUX2
cut-like homeobox 2
chr9_+_101717278 0.262 STX17
syntaxin 17
chr6_+_32713160 0.260 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr2_+_68445821 0.260 NM_002664
PLEK
pleckstrin
chr6_-_32665409 0.259 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr14_-_19843918 0.259 TTC5
tetratricopeptide repeat domain 5
chrX_-_141120722 0.259 NM_016249
MAGEC2
melanoma antigen family C, 2
chr10_+_97505398 0.258 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr17_-_54587581 0.258 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr14_+_22911857 0.258 NM_172314
NM_022789
IL25

interleukin 25

chrX_-_153698930 0.254 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr2_+_173940179 0.253 CDCA7
cell division cycle associated 7
chr1_+_190811479 0.250 NM_002922
RGS1
regulator of G-protein signaling 1
chr19_+_59973074 0.249 NM_014218
KIR2DS2
KIR2DL1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr4_-_83566246 0.247 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_-_38379031 0.246 ATL2
atlastin GTPase 2
chr12_-_9777126 0.244 NM_172004
CLECL1
C-type lectin-like 1
chr1_+_179269761 0.244 MR1
major histocompatibility complex, class I-related
chr22_-_38619739 0.244 NM_152512
ENTHD1
ENTH domain containing 1
chr7_-_135263737 0.243 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr2_-_39310176 0.242 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr4_-_100431093 0.242 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr1_+_179269689 0.241 MR1
major histocompatibility complex, class I-related
chr4_+_166350620 0.240 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr10_-_48426868 0.239 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr1_+_84646621 0.237 NM_058248
DNASE2B
deoxyribonuclease II beta
chr5_-_37220702 0.235 C5orf42
chromosome 5 open reading frame 42
chrX_-_49347279 0.234 NM_003785
PAGE1
P antigen family, member 1 (prostate associated)
chr10_-_6144119 0.233 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr10_+_88975184 0.232 NM_001099338
FAM22A
FAM22D
family with sequence similarity 22, member A
family with sequence similarity 22, member D
chr16_-_3567354 0.230 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr17_-_36192311 0.228 NM_181537
KRT27
keratin 27

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.02 4.21e-22 GO:0007608 sensory perception of smell
3.69 2.29e-20 GO:0007606 sensory perception of chemical stimulus
2.38 9.91e-11 GO:0007600 sensory perception
1.35 3.51e-09 GO:0050896 response to stimulus
1.76 1.92e-07 GO:0003008 system process
1.80 3.32e-06 GO:0050877 neurological system process
1.97 2.51e-04 GO:0006955 immune response
9.99 6.94e-04 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
1.86 1.70e-03 GO:0006952 defense response
1.27 1.99e-03 GO:0032501 multicellular organismal process
2.16 3.93e-03 GO:0050776 regulation of immune response
1.62 8.68e-03 GO:0002376 immune system process
2.59 1.47e-02 GO:0002253 activation of immune response
2.35 2.19e-02 GO:0050778 positive regulation of immune response
3.94 3.54e-02 GO:0002449 lymphocyte mediated immunity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.42 3.03e-08 GO:0071944 cell periphery
1.42 3.09e-08 GO:0005886 plasma membrane
12.13 1.51e-05 GO:0042613 MHC class II protein complex
1.27 5.95e-05 GO:0031224 intrinsic to membrane
1.28 6.16e-05 GO:0016021 integral to membrane
1.22 3.85e-04 GO:0044425 membrane part
5.97 3.19e-03 GO:0042611 MHC protein complex
1.16 7.90e-03 GO:0016020 membrane
1.38 3.00e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.21 4.82e-24 GO:0004984 olfactory receptor activity
2.19 1.72e-14 GO:0004888 transmembrane receptor activity
2.51 4.70e-14 GO:0004930 G-protein coupled receptor activity
1.86 8.07e-11 GO:0004872 receptor activity
1.70 4.43e-09 GO:0004871 signal transducer activity
1.70 4.43e-09 GO:0060089 molecular transducer activity
4.78 3.56e-02 GO:0003823 antigen binding