Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.904


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNTchr1_-_149115771-0.381.5e-01Click!
AHRchr7_+_173047070.282.9e-01Click!
ARNT2chr15_+_78520634-0.146.0e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_6298284 2.175 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr3_-_162305319 2.121 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr1_+_61320213 2.119 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr5_+_60663842 1.931 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr12_-_87498225 1.917 NM_000899
NM_003994
KITLG

KIT ligand

chr4_-_57671112 1.690 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671307 1.681 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671273 1.662 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr9_-_25668230 1.584 TUSC1
tumor suppressor candidate 1
chr21_-_38954433 1.485 ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr11_-_78829342 1.477 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr16_+_81218142 1.462 CDH13
cadherin 13, H-cadherin (heart)
chr7_-_27149750 1.383 NM_019102
HOXA5
homeobox A5
chr16_-_86082818 1.309 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr1_+_199519202 1.264 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr16_+_81218074 1.225 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr7_-_27136876 1.179 NM_002141
HOXA4
homeobox A4
chr12_-_74710741 1.166 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr6_-_10520592 1.144 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr21_-_35182842 1.128 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 153 entries
enrichment   p-value GO term description
6.78 1.53e-02 GO:0010719 negative regulation of epithelial to mesenchymal transition
4.43 1.39e-04 GO:0010717 regulation of epithelial to mesenchymal transition
3.42 2.71e-02 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
2.86 1.49e-02 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.81 2.05e-02 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
2.61 4.26e-05 GO:0006469 negative regulation of protein kinase activity
2.55 4.85e-02 GO:0010563 negative regulation of phosphorus metabolic process
2.55 4.85e-02 GO:0045936 negative regulation of phosphate metabolic process
2.47 2.06e-04 GO:0033673 negative regulation of kinase activity
2.42 6.42e-05 GO:0006184 GTP catabolic process
2.34 1.09e-03 GO:0051348 negative regulation of transferase activity
2.30 2.08e-04 GO:0046039 GTP metabolic process
2.29 2.59e-03 GO:0048705 skeletal system morphogenesis
2.29 3.95e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.29 7.40e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.27 4.89e-03 GO:0022604 regulation of cell morphogenesis
2.10 4.40e-02 GO:0060537 muscle tissue development
2.01 8.48e-04 GO:0009261 ribonucleotide catabolic process
1.99 1.48e-03 GO:0009154 purine ribonucleotide catabolic process
1.99 1.85e-03 GO:0009203 ribonucleoside triphosphate catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
1.43 1.04e-02 GO:0044451 nucleoplasm part
1.37 2.73e-04 GO:0005654 nucleoplasm
1.32 1.04e-04 GO:0031981 nuclear lumen
1.30 2.54e-05 GO:0070013 intracellular organelle lumen
1.29 5.32e-05 GO:0043233 organelle lumen
1.29 5.42e-05 GO:0031974 membrane-enclosed lumen
1.28 2.09e-04 GO:0044428 nuclear part
1.23 2.55e-11 GO:0005634 nucleus
1.23 2.47e-02 GO:0005829 cytosol
1.16 4.87e-10 GO:0005737 cytoplasm
1.15 1.23e-10 GO:0043231 intracellular membrane-bounded organelle
1.15 1.82e-10 GO:0043227 membrane-bounded organelle
1.14 1.78e-18 GO:0005622 intracellular
1.13 1.53e-14 GO:0044424 intracellular part
1.13 2.83e-09 GO:0043229 intracellular organelle
1.13 3.95e-09 GO:0043226 organelle
1.13 2.82e-03 GO:0044444 cytoplasmic part
1.13 8.06e-03 GO:0044446 intracellular organelle part
1.13 1.52e-02 GO:0044422 organelle part
1.05 3.12e-05 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
3.58 3.21e-02 GO:0019003 GDP binding
1.98 6.39e-04 GO:0003924 GTPase activity
1.76 2.59e-04 GO:0005525 GTP binding
1.70 9.60e-04 GO:0019001 guanyl nucleotide binding
1.70 9.60e-04 GO:0032561 guanyl ribonucleotide binding
1.48 3.45e-03 GO:0043565 sequence-specific DNA binding
1.46 5.62e-05 GO:0030528 transcription regulator activity
1.43 7.31e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.43 9.34e-03 GO:0016462 pyrophosphatase activity
1.43 1.37e-02 GO:0017111 nucleoside-triphosphatase activity
1.42 8.11e-03 GO:0003723 RNA binding
1.42 9.02e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.41 1.64e-03 GO:0001071 nucleic acid binding transcription factor activity
1.41 1.64e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.40 2.63e-10 GO:0000166 nucleotide binding
1.33 5.62e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.32 1.08e-04 GO:0017076 purine nucleotide binding
1.31 1.90e-04 GO:0032553 ribonucleotide binding
1.31 1.90e-04 GO:0032555 purine ribonucleotide binding
1.21 6.64e-15 GO:0005515 protein binding