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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.904

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_6298284	2.175	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr3_-_162305319	2.121	NM_033169 NM_001038628 NM_003781 NM_033167 NM_033168	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_61320213	2.119	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr5_+_60663842	1.931	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr12_-_87498225	1.917	NM_000899 NM_003994	KITLG	KIT ligand
chr4_-_57671112	1.690		IGFBP7	insulin-like growth factor binding protein 7
chr4_-_57671307	1.681		IGFBP7	insulin-like growth factor binding protein 7
chr4_-_57671273	1.662	NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr9_-_25668230	1.584		TUSC1	tumor suppressor candidate 1
chr21_-_38954433	1.485		ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr11_-_78829342	1.477	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr16_+_81218142	1.462		CDH13	cadherin 13, H-cadherin (heart)
chr7_-_27149750	1.383	NM_019102	HOXA5	homeobox A5
chr16_-_86082818	1.309	NM_015144	ZCCHC14	zinc finger, CCHC domain containing 14
chr1_+_199519202	1.264	NM_000299 NM_001005337	PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr16_+_81218074	1.225	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr7_-_27136876	1.179	NM_002141	HOXA4	homeobox A4
chr12_-_74710741	1.166		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr6_-_10520592	1.144	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr21_-_35182842	1.128	NM_001001890 NM_001122607	RUNX1	runt-related transcription factor 1
chr21_-_35182873	1.100		RUNX1	runt-related transcription factor 1
chr3_-_65999548	1.075	NM_001033057 NM_004742 NM_015520	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_-_61680510	1.074	NM_022103	ZNF667	zinc finger protein 667
chrX_-_128616594	1.072	NM_017413	APLN	apelin
chr1_+_85819004	0.994	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr6_+_21701942	0.985	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr3_-_31998241	0.959	NM_001174060 NM_017784	OSBPL10	oxysterol binding protein-like 10
chr18_+_19523526	0.958	NM_001127717 NM_198129	LAMA3	laminin, alpha 3
chr6_-_10520264	0.950		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_-_83494198	0.932		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_+_219141546	0.930		RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr12_-_88269884	0.930		DUSP6	dual specificity phosphatase 6
chr7_+_113513828	0.925		FOXP2	forkhead box P2
chr16_-_85099941	0.920		LOC400550	hypothetical LOC400550
chr2_+_29191711	0.913	NM_024692	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr3_+_195336625	0.877	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr22_-_34754343	0.868	NM_001082578 NM_001082579	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_-_115120251	0.862	NM_024590	ARSJ	arylsulfatase family, member J
chr6_+_1336077	0.853
chr15_-_61461127	0.848	NM_001218 NM_206925	CA12	carbonic anhydrase XII
chr2_+_206255376	0.839	NM_003872 NM_018534 NM_201264 NM_201266 NM_201267 NM_201279	NRP2	neuropilin 2
chr18_-_21184824	0.837
chr15_-_69194854	0.835	NM_001102658	CT62	cancer/testis antigen 62
chr17_+_76988134	0.834	NM_001080519	BAHCC1	BAH domain and coiled-coil containing 1
chr13_-_32822759	0.823		STARD13	StAR-related lipid transfer (START) domain containing 13
chr4_-_122063118	0.822	NM_018699	PRDM5	PR domain containing 5
chr3_+_195336631	0.815		HES1	hairy and enhancer of split 1, (Drosophila)
chr17_-_8000362	0.805		PER1	period homolog 1 (Drosophila)
chr10_+_102782151	0.804		SFXN3	sideroflexin 3
chr3_-_31997738	0.804		OSBPL10	oxysterol binding protein-like 10
chr1_-_203557379	0.800	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr15_-_27901828	0.793	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr7_+_113513726	0.791		FOXP2	forkhead box P2
chr7_-_27120015	0.777		HOXA3	homeobox A3
chr15_-_61460967	0.748		CA12	carbonic anhydrase XII
chr19_+_50663089	0.745	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr18_-_5533967	0.740	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr1_-_58815415	0.730		TACSTD2	tumor-associated calcium signal transducer 2
chr20_+_51022352	0.726	NM_173485	TSHZ2	teashirt zinc finger homeobox 2
chr7_-_131911768	0.718		PLXNA4	plexin A4
chr3_+_189354167	0.717	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chrX_+_17303798	0.711		NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr3_+_31998269	0.711	NM_001137674	ZNF860	zinc finger protein 860
chr1_+_219119623	0.709		HLX	H2.0-like homeobox
chr14_+_73073570	0.708	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr9_-_109290528	0.704		KLF4	Kruppel-like factor 4 (gut)
chr5_-_172688024	0.698		STC2	stanniocalcin 2
chr10_+_102782156	0.694		SFXN3	sideroflexin 3
chr3_+_30623376	0.693		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr2_+_219141761	0.689	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr5_-_172687798	0.682		STC2	stanniocalcin 2
chr10_+_124210980	0.677	NM_002775	HTRA1	HtrA serine peptidase 1
chr1_+_219119468	0.674		HLX	H2.0-like homeobox
chr20_+_51023159	0.663		TSHZ2	teashirt zinc finger homeobox 2
chr4_-_143987053	0.663	NM_001101669 NM_003866	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr13_-_37341859	0.655	NM_001135955 NM_001135956 NM_001135957 NM_001135958 NM_003306 NM_016179	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chr2_-_219141199	0.643	NM_020935	USP37	ubiquitin specific peptidase 37
chr16_+_22733307	0.640	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr9_-_112381593	0.632	NM_153366	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr20_-_49818306	0.629	NM_006045	ATP9A	ATPase, class II, type 9A
chr5_-_16989290	0.627		MYO10	myosin X
chr4_-_103968104	0.626	NM_003340 NM_181886 NM_181888 NM_181889	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr5_-_16989371	0.623	NM_012334	MYO10	myosin X
chr1_+_208472817	0.622	NM_019605	SERTAD4	SERTA domain containing 4
chr15_-_27901628	0.618		TJP1	tight junction protein 1 (zona occludens 1)
chr13_-_77391525	0.614
chr9_-_13269562	0.613		MPDZ	multiple PDZ domain protein
chr8_+_69026895	0.612		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr18_-_20231783	0.612	NM_080597	OSBPL1A	oxysterol binding protein-like 1A
chr19_-_2378581	0.607		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr7_+_113513600	0.606		FOXP2	forkhead box P2
chr3_-_71196696	0.604		FOXP1	forkhead box P1
chr9_-_109290107	0.599		KLF4	Kruppel-like factor 4 (gut)
chr20_-_10602429	0.597	NM_000214	JAG1	jagged 1
chr5_+_63497408	0.595	NM_001113561 NM_178532	RNF180	ring finger protein 180
chr1_+_199975674	0.592		NAV1	neuron navigator 1
chr3_-_191321367	0.589		LEPREL1	leprecan-like 1
chr5_+_151131709	0.588		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr18_+_45342398	0.583	NM_006033	LIPG	lipase, endothelial
chr3_-_129024665	0.582	NM_001003794	MGLL	monoglyceride lipase
chr18_-_20231709	0.582		OSBPL1A	oxysterol binding protein-like 1A
chr1_+_182622987	0.577		C1orf21	chromosome 1 open reading frame 21
chr20_-_49818268	0.576		ATP9A	ATPase, class II, type 9A
chr10_+_17311307	0.568		VIM	vimentin
chr17_-_60208083	0.566		LOC146880	hypothetical LOC146880
chr10_+_17311283	0.566		VIM	vimentin
chr10_+_17311282	0.565		VIM	vimentin
chr10_+_17311242	0.565		VIM	vimentin
chr4_+_81337663	0.560	NM_001099403	PRDM8	PR domain containing 8
chr7_-_131911808	0.559	NM_001105543 NM_020911	PLXNA4	plexin A4
chr22_-_17891777	0.557		CLDN5	claudin 5
chr5_-_107034484	0.557	NM_001962	EFNA5	ephrin-A5
chr10_+_17311347	0.553		VIM	vimentin
chr7_+_28415495	0.552		LOC401317	hypothetical LOC401317
chr1_+_216586199	0.552		TGFB2	transforming growth factor, beta 2
chr19_+_12966970	0.552	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_223907283	0.549	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr10_+_114700775	0.547		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr15_+_96304942	0.533		ARRDC4	arrestin domain containing 4
chr19_-_2378530	0.533		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr15_+_37660568	0.531	NM_003246	THBS1	thrombospondin 1
chr3_-_49424427	0.529		RHOA	ras homolog gene family, member A
chr11_-_44928803	0.528	NM_001076787 NM_006034	TP53I11	tumor protein p53 inducible protein 11
chr8_-_125809831	0.526	NM_014751	MTSS1	metastasis suppressor 1
chr11_+_102485293	0.526	NM_001080463 NM_001377	DYNC2H1	dynein, cytoplasmic 2, heavy chain 1
chr1_-_203916239	0.522	NM_033102	SLC45A3	solute carrier family 45, member 3
chr8_+_69027277	0.522		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_+_116099648	0.519	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr1_+_181258952	0.519	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr7_+_44110527	0.518		AEBP1	AE binding protein 1
chr3_-_49424413	0.516		RHOA	ras homolog gene family, member A
chr1_+_199975563	0.515	NM_001167738	NAV1	neuron navigator 1
chr16_+_30617962	0.513	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr1_+_181259317	0.513
chr3_-_45242072	0.511		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr5_+_42459568	0.507	NM_000163	GHR	growth hormone receptor
chr15_+_96304911	0.505	NM_183376	ARRDC4	arrestin domain containing 4
chr2_-_101291483	0.504	NM_173647	RNF149	ring finger protein 149
chr3_-_186353421	0.503	NM_001025266	C3orf70	chromosome 3 open reading frame 70
chr8_+_1759502	0.500	NM_014629	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10
chr8_+_102574012	0.498		GRHL2	grainyhead-like 2 (Drosophila)
chr17_+_19081267	0.497	NM_001102664 NM_014964 NM_148921	EPN2	epsin 2
chr12_-_41269679	0.496	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr4_-_103967784	0.496	NM_181887 NM_181891	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr12_-_53099203	0.493		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr16_+_22732982	0.493		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr10_-_30065760	0.492		SVIL	supervillin
chr8_-_103737058	0.492	NM_005655	KLF10	Kruppel-like factor 10
chr1_+_32992131	0.490
chr6_+_3696224	0.489
chr2_+_219283751	0.488	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4
chr8_+_69027166	0.480		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr17_+_58058783	0.475		MRC2	mannose receptor, C type 2
chr9_-_94472090	0.474		IPPK	inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr13_-_39075200	0.469		LHFP	lipoma HMGIC fusion partner
chr17_-_35510074	0.467		NR1D1	nuclear receptor subfamily 1, group D, member 1
chr7_+_16652282	0.461	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2
chr8_+_102573837	0.459	NM_024915	GRHL2	grainyhead-like 2 (Drosophila)
chr15_+_81907176	0.459		SH3GL3	SH3-domain GRB2-like 3
chr8_+_69027143	0.454	NM_024870 NM_025170	PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr11_-_2907169	0.452	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr9_-_109291866	0.451	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr3_+_157875063	0.451		TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr4_-_140696740	0.451	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr12_+_64504835	0.448		HMGA2	high mobility group AT-hook 2
chr3_-_49424397	0.446		RHOA	ras homolog gene family, member A
chr1_-_203916160	0.443		SLC45A3	solute carrier family 45, member 3
chr15_-_73719546	0.443	NM_018285	IMP3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr3_-_189354510	0.442		LOC339929	hypothetical LOC339929
chr11_-_86061003	0.441	NM_006680	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chrX_+_149282097	0.441	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr10_+_124211353	0.440		HTRA1	HtrA serine peptidase 1
chr1_+_64709063	0.440	NM_020925	CACHD1	cache domain containing 1
chr20_+_13924263	0.437		MACROD2	MACRO domain containing 2
chr7_-_84654106	0.435		SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr11_+_66827563	0.434		SSH3	slingshot homolog 3 (Drosophila)
chr1_+_1437400	0.434		ATAD3A ATAD3B	ATPase family, AAA domain containing 3A ATPase family, AAA domain containing 3B
chr1_+_199975271	0.433		NAV1	neuron navigator 1
chr19_-_63301418	0.433	NM_001145543 NM_001145544 NM_023926	ZSCAN18	zinc finger and SCAN domain containing 18
chr13_-_39075304	0.432		LHFP	lipoma HMGIC fusion partner
chr1_+_61319976	0.431	NM_001145512	NFIA	nuclear factor I/A
chr19_-_63301386	0.426		ZSCAN18	zinc finger and SCAN domain containing 18
chr7_-_93357881	0.424	NM_006528	TFPI2	tissue factor pathway inhibitor 2
chrX_-_18282698	0.423	NM_006089	SCML2	sex comb on midleg-like 2 (Drosophila)
chr5_+_151131707	0.421		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr12_-_24606616	0.421	NM_152989	SOX5	SRY (sex determining region Y)-box 5
chr3_+_195888701	0.420		FAM43A	family with sequence similarity 43, member A
chr3_-_49424380	0.419		RHOA	ras homolog gene family, member A
chr17_+_52026058	0.419	NM_005450	NOG	noggin
chr11_-_87548199	0.417	NM_022337	RAB38	RAB38, member RAS oncogene family
chr20_-_10602139	0.416		JAG1	jagged 1
chr5_+_151131704	0.416		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr2_-_160972606	0.414		RBMS1	RNA binding motif, single stranded interacting protein 1
chr10_-_35970363	0.413	NM_031866	FZD8	frizzled homolog 8 (Drosophila)
chr20_+_13924014	0.411	NM_080676	MACROD2	MACRO domain containing 2
chr15_+_78775008	0.411		FAM108C1	family with sequence similarity 108, member C1
chr7_-_5429702	0.409	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr2_+_10101081	0.408	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr3_+_157874898	0.408	NM_015508	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr3_-_49424361	0.407		RHOA	ras homolog gene family, member A

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	5.59e-16	GO:0050794	regulation of cellular process
1.21	1.61e-13	GO:0050789	regulation of biological process
1.19	1.70e-12	GO:0065007	biological regulation
1.30	3.64e-12	GO:0044260	cellular macromolecule metabolic process
1.12	7.99e-12	GO:0009987	cellular process
1.22	3.15e-11	GO:0044237	cellular metabolic process
1.31	2.16e-09	GO:0031323	regulation of cellular metabolic process
1.31	8.36e-09	GO:0060255	regulation of macromolecule metabolic process
1.35	1.47e-08	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	4.15e-08	GO:0008152	metabolic process
1.29	4.33e-08	GO:0080090	regulation of primary metabolic process
1.27	4.53e-08	GO:0019222	regulation of metabolic process
1.19	8.07e-08	GO:0044238	primary metabolic process
1.23	1.37e-07	GO:0043170	macromolecule metabolic process
1.44	3.31e-07	GO:0023051	regulation of signaling
1.33	3.32e-07	GO:0048518	positive regulation of biological process
1.41	4.00e-07	GO:0010467	gene expression
1.26	5.75e-07	GO:0032502	developmental process
1.70	7.72e-07	GO:0045595	regulation of cell differentiation
1.29	8.85e-07	GO:0034641	cellular nitrogen compound metabolic process
1.46	9.13e-07	GO:0007399	nervous system development
1.68	1.92e-06	GO:0019220	regulation of phosphate metabolic process
1.68	1.92e-06	GO:0051174	regulation of phosphorus metabolic process
1.26	2.14e-06	GO:0023052	signaling
1.27	3.98e-06	GO:0007275	multicellular organismal development
1.44	5.49e-06	GO:0009966	regulation of signal transduction
1.27	5.59e-06	GO:0006807	nitrogen compound metabolic process
1.57	6.21e-06	GO:0050793	regulation of developmental process
1.30	6.24e-06	GO:0048731	system development
1.39	6.85e-06	GO:0016070	RNA metabolic process
1.66	7.05e-06	GO:0042325	regulation of phosphorylation
1.32	7.62e-06	GO:0048522	positive regulation of cellular process
1.27	8.46e-06	GO:0048856	anatomical structure development
1.34	8.98e-06	GO:0048523	negative regulation of cellular process
1.51	9.29e-06	GO:0051246	regulation of protein metabolic process
1.46	1.34e-05	GO:0009893	positive regulation of metabolic process
1.52	1.44e-05	GO:0032268	regulation of cellular protein metabolic process
1.65	3.90e-05	GO:0001932	regulation of protein phosphorylation
2.61	4.26e-05	GO:0006469	negative regulation of protein kinase activity
1.31	5.20e-05	GO:0048519	negative regulation of biological process
2.42	6.42e-05	GO:0006184	GTP catabolic process
1.29	8.29e-05	GO:0044267	cellular protein metabolic process
1.24	9.41e-05	GO:0007165	signal transduction
1.45	1.06e-04	GO:0031325	positive regulation of cellular metabolic process
1.77	1.07e-04	GO:0023057	negative regulation of signaling
1.74	1.18e-04	GO:0045859	regulation of protein kinase activity
4.43	1.39e-04	GO:0010717	regulation of epithelial to mesenchymal transition
1.49	1.98e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.47	2.06e-04	GO:0033673	negative regulation of kinase activity
2.30	2.08e-04	GO:0046039	GTP metabolic process
1.86	2.47e-04	GO:0045597	positive regulation of cell differentiation
1.38	2.58e-04	GO:0009653	anatomical structure morphogenesis
1.30	2.85e-04	GO:0090304	nucleic acid metabolic process
1.55	2.94e-04	GO:2000026	regulation of multicellular organismal development
1.46	3.05e-04	GO:0010646	regulation of cell communication
1.32	3.70e-04	GO:0030154	cell differentiation
1.51	4.30e-04	GO:0009891	positive regulation of biosynthetic process
1.31	4.59e-04	GO:0048869	cellular developmental process
1.50	4.68e-04	GO:0006351	transcription, DNA-dependent
1.69	4.81e-04	GO:0043549	regulation of kinase activity
1.43	4.83e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.72	4.93e-04	GO:0010648	negative regulation of cell communication
1.26	7.73e-04	GO:0009889	regulation of biosynthetic process
1.71	7.85e-04	GO:0051094	positive regulation of developmental process
2.01	8.48e-04	GO:0009261	ribonucleotide catabolic process
1.74	8.95e-04	GO:0009968	negative regulation of signal transduction
1.87	8.99e-04	GO:0009144	purine nucleoside triphosphate metabolic process
1.84	9.22e-04	GO:0001501	skeletal system development
1.88	1.06e-03	GO:0001944	vasculature development
2.34	1.09e-03	GO:0051348	negative regulation of transferase activity
1.85	1.09e-03	GO:0009141	nucleoside triphosphate metabolic process
1.51	1.18e-03	GO:0031399	regulation of protein modification process
1.34	1.27e-03	GO:0009059	macromolecule biosynthetic process
1.81	1.32e-03	GO:0009259	ribonucleotide metabolic process
1.88	1.33e-03	GO:0071900	regulation of protein serine/threonine kinase activity
1.64	1.43e-03	GO:0051338	regulation of transferase activity
1.99	1.48e-03	GO:0009154	purine ribonucleotide catabolic process
1.85	1.49e-03	GO:0009199	ribonucleoside triphosphate metabolic process
1.25	1.54e-03	GO:0031326	regulation of cellular biosynthetic process
1.90	1.68e-03	GO:0001568	blood vessel development
1.52	1.70e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.82	1.73e-03	GO:0060284	regulation of cell development
1.99	1.85e-03	GO:0009203	ribonucleoside triphosphate catabolic process
1.99	1.85e-03	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.48	1.97e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.98	2.18e-03	GO:0009146	purine nucleoside triphosphate catabolic process
1.38	2.41e-03	GO:0051239	regulation of multicellular organismal process
1.72	2.41e-03	GO:0006163	purine nucleotide metabolic process
1.44	2.57e-03	GO:0032774	RNA biosynthetic process
2.29	2.59e-03	GO:0048705	skeletal system morphogenesis
1.83	2.82e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.33	3.08e-03	GO:0034645	cellular macromolecule biosynthetic process
1.96	3.52e-03	GO:0009143	nucleoside triphosphate catabolic process
1.63	3.65e-03	GO:0000904	cell morphogenesis involved in differentiation
1.91	3.86e-03	GO:0006195	purine nucleotide catabolic process
2.29	3.95e-03	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.49	4.59e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	4.83e-03	GO:0010468	regulation of gene expression
2.27	4.89e-03	GO:0022604	regulation of cell morphogenesis
1.21	5.28e-03	GO:0016043	cellular component organization
1.48	5.36e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.53	5.76e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.77	6.11e-03	GO:0009150	purine ribonucleotide metabolic process
1.24	6.18e-03	GO:0071842	cellular component organization at cellular level
1.24	6.81e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.20	6.82e-03	GO:0071840	cellular component organization or biogenesis
1.24	7.24e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	7.27e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.55	7.38e-03	GO:0000902	cell morphogenesis
2.29	7.40e-03	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.94	7.55e-03	GO:0048514	blood vessel morphogenesis
1.44	8.27e-03	GO:0022008	neurogenesis
1.84	8.98e-03	GO:0009166	nucleotide catabolic process
1.86	9.25e-03	GO:0072523	purine-containing compound catabolic process
1.59	9.94e-03	GO:0048585	negative regulation of response to stimulus
1.52	1.10e-02	GO:0006396	RNA processing
1.44	1.17e-02	GO:0048699	generation of neurons
1.79	1.22e-02	GO:0051270	regulation of cellular component movement
1.29	1.24e-02	GO:0048513	organ development
1.23	1.43e-02	GO:0051171	regulation of nitrogen compound metabolic process
2.86	1.49e-02	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
6.78	1.53e-02	GO:0010719	negative regulation of epithelial to mesenchymal transition
1.49	1.81e-02	GO:0009890	negative regulation of biosynthetic process
1.51	1.84e-02	GO:0045893	positive regulation of transcription, DNA-dependent
2.81	2.05e-02	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
1.62	2.17e-02	GO:0007268	synaptic transmission
1.58	2.21e-02	GO:0019226	transmission of nerve impulse
1.58	2.21e-02	GO:0035637	multicellular organismal signaling
1.24	2.27e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.28	2.29e-02	GO:0048583	regulation of response to stimulus
1.28	2.35e-02	GO:0006464	protein modification process
1.40	2.36e-02	GO:0032879	regulation of localization
1.49	2.37e-02	GO:0051254	positive regulation of RNA metabolic process
1.62	2.41e-02	GO:0072521	purine-containing compound metabolic process
1.41	2.43e-02	GO:0048468	cell development
3.42	2.71e-02	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
1.56	2.84e-02	GO:0007417	central nervous system development
1.48	2.93e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.77	3.06e-02	GO:0061061	muscle structure development
1.90	3.41e-02	GO:0043405	regulation of MAP kinase activity
1.24	3.44e-02	GO:0051252	regulation of RNA metabolic process
1.17	3.47e-02	GO:0051716	cellular response to stimulus
1.97	3.60e-02	GO:0030900	forebrain development
1.47	3.81e-02	GO:0010628	positive regulation of gene expression
1.31	3.91e-02	GO:0065009	regulation of molecular function
2.10	4.40e-02	GO:0060537	muscle tissue development
1.35	4.43e-02	GO:0050790	regulation of catalytic activity
1.74	4.54e-02	GO:0040012	regulation of locomotion
2.55	4.85e-02	GO:0010563	negative regulation of phosphorus metabolic process
2.55	4.85e-02	GO:0045936	negative regulation of phosphate metabolic process
1.60	4.90e-02	GO:0008285	negative regulation of cell proliferation
1.54	4.96e-02	GO:0006753	nucleoside phosphate metabolic process
1.54	4.96e-02	GO:0009117	nucleotide metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	1.78e-18	GO:0005622	intracellular
1.13	1.53e-14	GO:0044424	intracellular part
1.23	2.55e-11	GO:0005634	nucleus
1.15	1.23e-10	GO:0043231	intracellular membrane-bounded organelle
1.15	1.82e-10	GO:0043227	membrane-bounded organelle
1.16	4.87e-10	GO:0005737	cytoplasm
1.13	2.83e-09	GO:0043229	intracellular organelle
1.13	3.95e-09	GO:0043226	organelle
1.30	2.54e-05	GO:0070013	intracellular organelle lumen
1.05	3.12e-05	GO:0044464	cell part
1.05	3.27e-05	GO:0005623	cell
1.29	5.32e-05	GO:0043233	organelle lumen
1.29	5.42e-05	GO:0031974	membrane-enclosed lumen
1.32	1.04e-04	GO:0031981	nuclear lumen
1.28	2.09e-04	GO:0044428	nuclear part
1.37	2.73e-04	GO:0005654	nucleoplasm
1.13	2.82e-03	GO:0044444	cytoplasmic part
1.13	8.06e-03	GO:0044446	intracellular organelle part
1.43	1.04e-02	GO:0044451	nucleoplasm part
1.13	1.52e-02	GO:0044422	organelle part
1.23	2.47e-02	GO:0005829	cytosol

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	6.64e-15	GO:0005515	protein binding
1.12	2.60e-14	GO:0005488	binding
1.40	2.63e-10	GO:0000166	nucleotide binding
1.46	5.62e-05	GO:0030528	transcription regulator activity
1.33	5.62e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.32	1.08e-04	GO:0017076	purine nucleotide binding
1.31	1.90e-04	GO:0032553	ribonucleotide binding
1.31	1.90e-04	GO:0032555	purine ribonucleotide binding
1.76	2.59e-04	GO:0005525	GTP binding
1.98	6.39e-04	GO:0003924	GTPase activity
1.21	7.61e-04	GO:0003676	nucleic acid binding
1.70	9.60e-04	GO:0019001	guanyl nucleotide binding
1.70	9.60e-04	GO:0032561	guanyl ribonucleotide binding
1.41	1.64e-03	GO:0001071	nucleic acid binding transcription factor activity
1.41	1.64e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.48	3.45e-03	GO:0043565	sequence-specific DNA binding
1.43	7.31e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.42	8.11e-03	GO:0003723	RNA binding
1.42	9.02e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
1.43	9.34e-03	GO:0016462	pyrophosphatase activity
1.43	1.37e-02	GO:0017111	nucleoside-triphosphatase activity
3.58	3.21e-02	GO:0019003	GDP binding