• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: NKX6-1,2.p2

Z-value: 0.882

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_169654742	2.220	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chrX_-_33139349	1.484	NM_004006	DMD	dystrophin
chr8_-_122722674	1.291	NM_005328	HAS2	hyaluronan synthase 2
chr12_+_32546243	1.204	NM_139241	FGD4	FYVE, RhoGEF and PH domain containing 4
chr21_-_35343065	1.018		RUNX1	runt-related transcription factor 1
chr1_+_194887630	0.999	NM_000186 NM_001014975	CFH	complement factor H
chr21_-_35343448	0.996		RUNX1	runt-related transcription factor 1
chr3_-_143230124	0.974	NM_001178141 NM_001178142 NM_006286	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr5_+_155686333	0.962	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr9_+_81376666	0.937	NM_007005	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_-_217267742	0.923		IGFBP5	insulin-like growth factor binding protein 5
chr21_-_35343456	0.919	NM_001754	RUNX1	runt-related transcription factor 1
chr4_-_138673078	0.903	NM_019035	PCDH18	protocadherin 18
chr7_+_93862137	0.894		COL1A2 PLAG1	collagen, type I, alpha 2 pleiomorphic adenoma gene 1
chr21_-_35343500	0.861		RUNX1	runt-related transcription factor 1
chr3_-_64186151	0.852	NM_198859	PRICKLE2	prickle homolog 2 (Drosophila)
chr3_-_15814678	0.830	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr1_-_53972464	0.825	NM_147193	GLIS1	GLIS family zinc finger 1
chr21_-_35343331	0.817		RUNX1	runt-related transcription factor 1
chr9_+_81377419	0.815		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_+_16191159	0.808	NM_054110	GALNTL2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr7_-_41709191	0.804	NM_002192	INHBA	inhibin, beta A
chr13_-_32658215	0.772	NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr1_+_78858675	0.768	NM_006820	IFI44L	interferon-induced protein 44-like
chr3_+_175641340	0.763		NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2
chr2_-_151052391	0.751	NM_005168	RND3	Rho family GTPase 3
chr3_-_11585264	0.737	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chr21_-_35343428	0.706		RUNX1	runt-related transcription factor 1
chr9_+_81377289	0.700		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_52939584	0.698	NM_001127322	CBX5	chromobox homolog 5
chr18_+_30544193	0.676	NM_001198941 NM_032978	DTNA	dystrobrevin, alpha
chr4_-_177427252	0.648	NM_080874	ASB5	ankyrin repeat and SOCS box containing 5
chr1_+_199884152	0.644		NAV1	neuron navigator 1
chr11_+_48466844	0.633	NM_001005512	OR4A47	olfactory receptor, family 4, subfamily A, member 47
chr4_-_138673014	0.610		PCDH18	protocadherin 18
chr12_-_52939636	0.606	NM_001127321	CBX5	chromobox homolog 5
chr3_-_21767819	0.598	NM_024697	ZNF385D	zinc finger protein 385D
chr2_-_225519974	0.591		DOCK10	dedicator of cytokinesis 10
chr5_-_111119846	0.590	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr19_+_24061717	0.581	NM_203282	ZNF254	zinc finger protein 254
chr14_+_62740878	0.569	NM_020663	RHOJ	ras homolog gene family, member J
chr12_-_90029328	0.558		LUM	lumican
chr6_-_37773609	0.548	NM_153487	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1
chr7_+_102340579	0.534	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr1_+_78888064	0.533	NM_006417	IFI44	interferon-induced protein 44
chr2_-_190635566	0.520	NM_005259	MSTN	myostatin
chr6_+_136214495	0.518	NM_018945	PDE7B	phosphodiesterase 7B
chr2_-_202271598	0.516	NM_033066	MPP4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr4_-_152368492	0.511		SH3D19	SH3 domain containing 19
chr15_+_47502666	0.509	NM_002009	FGF7	fibroblast growth factor 7
chr8_+_79591074	0.508		PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr10_+_31650069	0.502	NM_001128128 NM_001174094	ZEB1	zinc finger E-box binding homeobox 1
chr19_+_12036513	0.495	NM_001136501	ZNF844	zinc finger protein 844
chr7_+_28692122	0.491	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr1_-_110735158	0.484	NM_004696	SLC16A4	solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr7_+_28305464	0.480	NM_182899	CREB5	cAMP responsive element binding protein 5
chr3_-_52269467	0.478		WDR82	WD repeat domain 82
chr12_-_90029672	0.476	NM_002345	LUM	lumican
chr8_-_72431274	0.461	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr7_-_76667045	0.458	NM_006682	FGL2	fibrinogen-like 2
chr20_+_11846536	0.456	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr2_+_12775814	0.451
chr12_+_74071116	0.444		GLIPR1L2	GLI pathogenesis-related 1 like 2
chr7_-_137337354	0.443	NM_194071	CREB3L2	cAMP responsive element binding protein 3-like 2
chr1_+_242691295	0.440	NM_001130957 NM_173807	C1orf101	chromosome 1 open reading frame 101
chr3_-_150903749	0.436	NM_001168278	WWTR1	WW domain containing transcription regulator 1
chr8_+_79590890	0.431	NM_006823 NM_181839	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr12_+_118100977	0.430	NM_014365	HSPB8	heat shock 22kDa protein 8
chr2_+_66519949	0.423		MEIS1	Meis homeobox 1
chr10_+_86174665	0.422		FAM190B	family with sequence similarity 190, member B
chr2_+_33213111	0.409	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr6_-_56824371	0.402		DST	dystonin
chr8_+_42671718	0.399	NM_000749	CHRNB3	cholinergic receptor, nicotinic, beta 3
chr1_-_152394215	0.393	NM_001159484 NM_207308	NUP210L	nucleoporin 210kDa-like
chr3_-_170348215	0.390	NM_001164000	MECOM	MDS1 and EVI1 complex locus
chr21_+_29439768	0.385		C21orf7	chromosome 21 open reading frame 7
chr2_-_188127430	0.378	NM_001032281 NM_006287	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr14_-_60185659	0.376	NM_005982	SIX1	SIX homeobox 1
chr2_+_108751033	0.375		RANBP2	RAN binding protein 2
chr8_+_133060353	0.370		EFR3A	EFR3 homolog A (S. cerevisiae)
chr8_-_133841988	0.369	NM_001145153 NM_144649	TMEM71	transmembrane protein 71
chr6_+_88026338	0.369		ZNF292	zinc finger protein 292
chr6_+_26071255	0.367		TRIM38	tripartite motif containing 38
chr8_-_72437020	0.360	NM_000503	EYA1	eyes absent homolog 1 (Drosophila)
chr8_-_37916803	0.356	NM_152413	GOT1L1	glutamic-oxaloacetic transaminase 1-like 1
chrX_+_47326746	0.355		TIMP1	TIMP metallopeptidase inhibitor 1
chr1_+_15145001	0.352	NM_001017999	KAZN	kazrin, periplakin interacting protein
chr1_-_219982049	0.350		DUSP10	dual specificity phosphatase 10
chr11_+_12265022	0.346	NM_032867	MICALCL	MICAL C-terminal like
chr4_+_120167721	0.342		SYNPO2	synaptopodin 2
chr1_-_219982081	0.339	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr1_-_195818927	0.337		DENND1B	DENN/MADD domain containing 1B
chr15_-_74941339	0.336	NM_001145923	SCAPER	S-phase cyclin A-associated protein in the ER
chr5_-_64813459	0.336	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr1_-_149115667	0.334		ARNT	aryl hydrocarbon receptor nuclear translocator
chr11_-_7684516	0.327	NM_198185	OVCH2	ovochymase 2 (gene/pseudogene)
chr7_-_13992351	0.327	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr1_-_219982016	0.327		DUSP10	dual specificity phosphatase 10
chr12_+_9871343	0.325	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chr11_+_65026382	0.321
chr2_-_188127294	0.321		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_+_72034735	0.316		POM121	POM121 membrane glycoprotein
chr1_+_154120170	0.313		SYT11	synaptotagmin XI
chr2_-_237987554	0.307		COL6A3	collagen, type VI, alpha 3
chr9_-_72673753	0.304	NM_001007470 NM_020952 NM_024971 NM_206944 NM_206945 NM_206946 NM_206947 NM_206948	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr13_-_98757634	0.303	NM_004951	GPR183	G protein-coupled receptor 183
chr1_+_12149662	0.303		TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr10_-_69661860	0.300	NM_145178	ATOH7	atonal homolog 7 (Drosophila)
chr6_+_26548678	0.298	NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr3_+_195688974	0.295		FLJ34208	hypothetical LOC401106
chr3_-_116272911	0.295	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chrX_+_47326594	0.294	NM_003254	TIMP1	TIMP metallopeptidase inhibitor 1
chr2_-_144994038	0.294		ZEB2	zinc finger E-box binding homeobox 2
chr2_-_237987545	0.290		COL6A3	collagen, type VI, alpha 3
chr2_-_217268492	0.287	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr2_-_162808123	0.287	NM_004460	FAP	fibroblast activation protein, alpha
chr6_+_26070957	0.287	NM_006355	TRIM38	tripartite motif containing 38
chr13_-_46368968	0.285	NM_000621 NM_001165947	HTR2A	5-hydroxytryptamine (serotonin) receptor 2A
chr2_-_237987579	0.282	NM_004369 NM_057164 NM_057165 NM_057166 NM_057167	COL6A3	collagen, type VI, alpha 3
chr2_-_237987553	0.281		COL6A3	collagen, type VI, alpha 3
chr6_-_80303822	0.280	NM_001122769 NM_181714	LCA5	Leber congenital amaurosis 5
chr1_-_199613427	0.274	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr11_+_93916653	0.273	NM_002033	PIWIL4 FUT4	piwi-like 4 (Drosophila) fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr18_-_12646730	0.272	NM_001128627	SPIRE1	spire homolog 1 (Drosophila)
chr11_-_56951628	0.271	NM_017611	SLC43A3	solute carrier family 43, member 3
chr21_-_34820916	0.270	NM_203418	RCAN1	regulator of calcineurin 1
chr12_-_52281050	0.268	NM_001130059	ATF7	activating transcription factor 7
chr1_+_108904191	0.267		FAM102B	family with sequence similarity 102, member B
chr15_+_87540238	0.267		ABHD2	abhydrolase domain containing 2
chr3_-_113495763	0.267	NM_183061	SLC9A10	solute carrier family 9, member 10
chrX_+_55951280	0.266
chr2_-_178681311	0.264	NM_001077197	PDE11A	phosphodiesterase 11A
chr12_-_51887266	0.263	NM_000889	ITGB7	integrin, beta 7
chr12_+_46799279	0.263	NM_000289	PFKM	phosphofructokinase, muscle
chr1_+_12149637	0.262	NM_001066	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr2_-_65447267	0.259		SPRED2	sprouty-related, EVH1 domain containing 2
chr8_-_23768242	0.257	NM_003155	STC1	stanniocalcin 1
chr2_-_227952249	0.255	NM_024795	TM4SF20	transmembrane 4 L six family member 20
chr4_+_120167770	0.253		SYNPO2	synaptopodin 2
chr20_-_45360903	0.251		ZMYND8	zinc finger, MYND-type containing 8
chr3_-_39209075	0.251	NM_194293 NM_001198621	XIRP1	xin actin-binding repeat containing 1
chr6_+_116956868	0.246	NM_153036	FAM26D	family with sequence similarity 26, member D
chr6_-_56824672	0.245		DST	dystonin
chr19_-_53912025	0.245	NM_182574	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator
chr6_+_96132064	0.245	NM_024641	MANEA	mannosidase, endo-alpha
chr13_+_22653059	0.244	NM_000231	SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_-_89261021	0.244	NM_018284	GBP3	guanylate binding protein 3
chr1_+_242582559	0.243	NM_001012970	C1orf100	chromosome 1 open reading frame 100
chr2_-_144711375	0.241	NM_024659	GTDC1	glycosyltransferase-like domain containing 1
chr5_-_88235624	0.241	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr1_-_149115686	0.241		ARNT	aryl hydrocarbon receptor nuclear translocator
chr5_+_35892747	0.239	NM_002185	IL7R	interleukin 7 receptor
chr6_-_50039776	0.239	NM_001037499	DEFB114	defensin, beta 114
chr12_-_92489652	0.235		LOC144481	hypothetical protein LOC144481
chr5_+_149977398	0.234	NM_001166209	SYNPO	synaptopodin
chr5_+_140719773	0.233	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr11_+_100063061	0.228	NM_152432	ARHGAP42	Rho GTPase activating protein 42
chr1_-_149115771	0.227		ARNT	aryl hydrocarbon receptor nuclear translocator
chr14_-_79748273	0.225	NM_000793 NM_013989	DIO2	deiodinase, iodothyronine, type II
chrX_+_80344253	0.224		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr1_+_12325632	0.224		VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr3_-_171070314	0.223	NM_024727	LRRC31	leucine rich repeat containing 31
chr15_-_87257553	0.221		MFGE8	milk fat globule-EGF factor 8 protein
chr17_-_36475652	0.220	NM_033184	KRTAP2-4	keratin associated protein 2-4
chr4_-_87593306	0.218	NM_002753	MAPK10	mitogen-activated protein kinase 10
chr21_-_35174742	0.218		RUNX1	runt-related transcription factor 1
chr1_-_199613406	0.218		TNNT2	troponin T type 2 (cardiac)
chrX_+_51503219	0.216	NM_018094	GSPT2	G1 to S phase transition 2
chr11_-_126375895	0.215	NM_001161707 NM_032531	KIRREL3	kin of IRRE like 3 (Drosophila)
chr4_+_166097548	0.215	NM_153027	C4orf39	chromosome 4 open reading frame 39
chr1_+_170656450	0.211	NM_139240	C1orf105	chromosome 1 open reading frame 105
chr13_-_20533629	0.209		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr10_+_28918672	0.208		WAC	WW domain containing adaptor with coiled-coil
chr1_-_20374273	0.208	NM_001105572	PLA2G2C	phospholipase A2, group IIC
chr14_-_94669547	0.206	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr2_-_198248828	0.205	NM_144629	RFTN2	raftlin family member 2
chr3_+_51550635	0.200	NM_015106	RAD54L2	RAD54-like 2 (S. cerevisiae)
chr14_+_87921818	0.199		SPATA7	spermatogenesis associated 7
chr11_+_59027624	0.197	NM_001004706	OR4D11	olfactory receptor, family 4, subfamily D, member 11
chr13_-_20533703	0.196	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr4_+_54790190	0.193		PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr14_+_100365162	0.193		MEG3	maternally expressed 3 (non-protein coding)
chr2_+_87536174	0.193		NCRNA00152	non-protein coding RNA 152
chr13_-_98708549	0.193	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr3_-_106903734	0.193		CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr1_+_242281199	0.193		ZNF238	zinc finger protein 238
chr1_+_156229686	0.191	NM_018240	KIRREL	kin of IRRE like (Drosophila)
chr11_-_73371945	0.188		UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chrX_-_19898302	0.187	NM_198279	CXorf23	chromosome X open reading frame 23
chr1_+_15128882	0.186	NM_001018001	KAZN	kazrin, periplakin interacting protein
chr6_+_147568795	0.183		STXBP5	syntaxin binding protein 5 (tomosyn)
chr6_-_66346417	0.183	NM_198283	EYS	eyes shut homolog (Drosophila)
chr5_+_95092384	0.182	NM_014899	RHOBTB3	Rho-related BTB domain containing 3
chrX_+_80344215	0.182		SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr12_+_10348311	0.180	NM_001114396	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr1_+_85300580	0.180	NM_145172	WDR63	WD repeat domain 63
chr4_+_187227302	0.180	NM_003265	TLR3	toll-like receptor 3
chr4_+_40953652	0.179	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr6_+_39868116	0.178
chr5_+_31229549	0.178	NM_004932	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.20	2.85e-02	GO:0050896	response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
13.16	2.80e-03	GO:0016011	dystroglycan complex
12.28	3.71e-02	GO:0016012	sarcoglycan complex

Nothing significant found in function category.