Motif ID: FOXD3.p2

Z-value: 1.074


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD3chr1_+_63561632-0.029.5e-01Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_19863716 2.394 RIN2
Ras and Rab interactor 2
chr3_+_138159396 1.948 NM_144717
IL20RB
interleukin 20 receptor beta
chr13_-_40491491 1.794 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr18_+_59405513 1.682 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_+_11242666 1.647 NM_001098211
HRH1
histamine receptor H1
chr13_-_40491405 1.497 ELF1
E74-like factor 1 (ets domain transcription factor)
chr18_+_27281729 1.473 NM_001944
DSG3
desmoglein 3
chr4_+_167013859 1.468 NM_012464
TLL1
tolloid-like 1
chr3_+_195336625 1.434 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr1_+_218768170 1.380 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr14_-_98807307 1.351 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr19_-_4782711 1.263 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr1_+_218768146 1.211 MARK1
MAP/microtubule affinity-regulating kinase 1
chr10_+_118177371 1.166 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr4_-_38710376 1.121 NM_024943
TMEM156
transmembrane protein 156
chr9_-_116608113 1.084 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr5_+_159368733 1.051 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr4_+_75393053 1.034 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr5_-_59100194 1.030 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_159368721 1.002 TTC1
tetratricopeptide repeat domain 1
chr3_+_190990142 0.986 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr5_+_159368690 0.982 TTC1
tetratricopeptide repeat domain 1
chr21_+_38550739 0.970 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_158948176 0.962 NM_001778
CD48
CD48 molecule
chr1_+_181421796 0.961 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr16_+_67235651 0.950 NM_001793
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr3_+_195336631 0.933 HES1
hairy and enhancer of split 1, (Drosophila)
chr19_-_4289750 0.915 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr21_-_38792173 0.911 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr16_+_80370400 0.864 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr22_+_36008511 0.843 CYTH4
cytohesin 4
chr3_+_133798770 0.830 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr1_+_13784553 0.809 NM_001006624
NM_001006625
PDPN

podoplanin

chr6_+_49626071 0.798 NM_001145652
C6orf141
chromosome 6 open reading frame 141
chr9_+_676640 0.791


chr1_-_100003936 0.789 NM_001013660
FRRS1
ferric-chelate reductase 1
chr22_+_36008465 0.787 CYTH4
cytohesin 4
chr19_+_12995782 0.784 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr22_+_36008369 0.751 NM_013385
CYTH4
cytohesin 4
chr1_-_27825178 0.749 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr4_-_90978469 0.731 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr3_-_184756101 0.720 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr13_-_85271329 0.712 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr2_-_215711313 0.707 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr15_-_38953628 0.698 NM_133639
RHOV
ras homolog gene family, member V
chr4_-_153820535 0.692 NM_152680
TMEM154
transmembrane protein 154
chr19_+_6415259 0.691 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr5_-_43432969 0.685 CCL28
chemokine (C-C motif) ligand 28
chr12_+_27066749 0.680 NM_004264
MED21
mediator complex subunit 21
chr4_+_100957003 0.679 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr20_+_51023159 0.674 TSHZ2
teashirt zinc finger homeobox 2
chr11_-_128399218 0.670 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr12_+_27066768 0.650 MED21
mediator complex subunit 21
chr10_-_116276560 0.640 ABLIM1
actin binding LIM protein 1
chr7_+_151284396 0.630 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr2_+_61225710 0.630 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr6_+_29963328 0.612 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr8_-_6407882 0.609 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr2_-_160765008 0.606 ITGB6
integrin, beta 6
chr12_-_28016182 0.606 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr6_+_10629550 0.593 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr10_+_47216925 0.591 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr3_-_191321367 0.587 LEPREL1
leprecan-like 1
chr10_-_46593923 0.583 NM_001040084
NM_001098845
ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr3_-_12561962 0.576 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr19_-_51319769 0.575 NM_207393
IGFL3
IGF-like family member 3
chr19_+_57564981 0.574 NM_001145434
ZNF880
zinc finger protein 880
chr19_+_42689881 0.572 ZNF793
zinc finger protein 793
chr12_+_29193399 0.572 FAR2
fatty acyl CoA reductase 2
chr22_+_43527101 0.563 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr10_+_47875229 0.548 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr10_-_98021144 0.543 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_-_11736946 0.536 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr12_-_15005761 0.533 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_+_89519004 0.530 HERC6
hect domain and RLD 6
chr2_+_102320148 0.530 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr6_+_31190505 0.527 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr6_+_26348539 0.527 NM_003540
HIST1H4F
histone cluster 1, H4f
chr5_+_145296313 0.526 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr1_+_61697209 0.522 NFIA
nuclear factor I/A
chr1_+_13782838 0.520 NM_006474
NM_198389
PDPN

podoplanin

chr4_+_89518898 0.508 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr14_-_60817946 0.506


chr14_-_60818263 0.506 NM_001017970
TMEM30B
transmembrane protein 30B
chr21_+_41719847 0.503 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr18_+_59705918 0.497 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr17_-_53847937 0.489 RNF43
ring finger protein 43
chr14_-_98807574 0.484 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr11_-_107969554 0.482 NM_015065
EXPH5
exophilin 5
chr3_-_191321601 0.472 NM_018192
LEPREL1
leprecan-like 1
chr1_-_159275334 0.469 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr3_-_194118321 0.463 MB21D2
Mab-21 domain containing 2
chr6_-_10520264 0.458 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_121798443 0.457 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr5_-_94442941 0.448 MCTP1
multiple C2 domains, transmembrane 1
chr19_+_42689680 0.441 NM_001013659
ZNF793
zinc finger protein 793
chr20_-_23014828 0.441 NM_012072
CD93
CD93 molecule
chr19_+_48772791 0.440 NM_001193621
LOC390940
hypothetical protein LOC390940
chr7_+_113842470 0.439 FOXP2
forkhead box P2
chr15_-_32398220 0.434 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_+_34993234 0.433 NM_005268
GJB5
gap junction protein, beta 5, 31.1kDa
chr12_+_46799279 0.431 NM_000289
PFKM
phosphofructokinase, muscle
chr2_-_20390601 0.429 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr15_-_61460967 0.427 CA12
carbonic anhydrase XII
chr1_+_179719338 0.426 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr6_+_148705817 0.425 SASH1
SAM and SH3 domain containing 1
chr19_+_3087026 0.423 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr7_-_87180499 0.413 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_-_160764819 0.404 NM_000888
ITGB6
integrin, beta 6
chr12_+_91620749 0.399 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr19_+_59820413 0.395 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr15_-_61461127 0.395 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr4_-_87989291 0.395 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr19_-_14853166 0.393 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chrX_+_123062143 0.391 STAG2
stromal antigen 2
chr9_-_25668230 0.390 TUSC1
tumor suppressor candidate 1
chr10_+_71231693 0.389 COL13A1
collagen, type XIII, alpha 1
chr17_-_26665194 0.389 EVI2B
ecotropic viral integration site 2B
chr19_-_61876057 0.388 NM_001005850
ZNF835
zinc finger protein 835
chr5_+_68746694 0.386 NM_001038603
MARVELD2
MARVEL domain containing 2
chr20_-_45848043 0.384 NM_018837
SULF2
sulfatase 2
chr5_+_108111421 0.383 NM_005246
FER
fer (fps/fes related) tyrosine kinase
chr6_+_153060722 0.383 NM_025107
MYCT1
myc target 1
chr17_-_26665213 0.380 EVI2B
ecotropic viral integration site 2B
chr1_-_159275357 0.379 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr3_+_123385219 0.379 NM_000388
CASR
calcium-sensing receptor
chr1_-_25164061 0.377 NM_001031680
RUNX3
runt-related transcription factor 3
chr9_+_27099138 0.375 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr8_+_69026895 0.374 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr5_-_58607673 0.374 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_149895390 0.373 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr17_-_26665144 0.373 EVI2B
ecotropic viral integration site 2B
chr12_+_53178834 0.372 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr8_+_54926920 0.370 NM_170587
RGS20
regulator of G-protein signaling 20
chr1_-_168310232 0.366 NM_014970
KIFAP3
kinesin-associated protein 3
chr16_+_67328805 0.360 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr12_-_83954185 0.360 NM_001100917
TSPAN19
tetraspanin 19
chr4_-_64957595 0.358 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr8_+_27687821 0.358 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr9_-_98815676 0.356 HIATL2
hippocampus abundant transcript-like 2
chrX_+_99726445 0.350 NM_022144
TNMD
tenomodulin
chr21_+_38550533 0.348 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr9_-_205892 0.348 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr2_-_158008763 0.347 NM_004288
CYTIP
cytohesin 1 interacting protein
chr6_-_32892705 0.346 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr17_-_26665220 0.341 NM_006495
EVI2B
ecotropic viral integration site 2B
chr10_+_71231649 0.341 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr7_+_113842284 0.337 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr14_+_20319049 0.337 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr3_+_123526700 0.336 NM_005213
CSTA
cystatin A (stefin A)
chr9_+_96176638 0.336 NM_032558
HIATL1
hippocampus abundant transcript-like 1
chr3_-_57505107 0.334 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr6_+_126282078 0.333 NCOA7
nuclear receptor coactivator 7
chr8_-_68821131 0.333 NM_020361
CPA6
carboxypeptidase A6
chr2_+_237143118 0.333 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr6_+_114285209 0.332 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_107485071 0.332 NTNG1
netrin G1
chr14_+_101345878 0.332 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr2_-_133145539 0.331 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr16_-_3567354 0.330 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr7_-_25234582 0.330 NM_022150
NPVF
neuropeptide VF precursor
chr8_+_123863224 0.329 ZHX2
zinc fingers and homeoboxes 2
chr21_-_42219849 0.329 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr22_+_44828338 0.328


chr12_+_21175394 0.327 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr12_+_111375382 0.327 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr11_+_20005704 0.320 NAV2
neuron navigator 2
chr13_+_20081940 0.320


chr12_-_120591938 0.320 NM_173855
MORN3
MORN repeat containing 3
chr9_+_92629525 0.319 NM_001174167
SYK
spleen tyrosine kinase
chr16_+_67328737 0.317 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr3_+_123779122 0.316 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr6_-_26358811 0.314 NM_021018
HIST1H3F
histone cluster 1, H3f
chr1_-_150044365 0.311 NM_001004432
LINGO4
leucine rich repeat and Ig domain containing 4
chr11_-_64327197 0.311 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr20_-_14266200 0.310 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr5_+_55182963 0.310 NM_139017
IL31RA
interleukin 31 receptor A
chr7_-_20223467 0.310 NM_182762
MACC1
metastasis associated in colon cancer 1
chr11_-_26550243 0.310 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr5_+_147562531 0.309 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr9_+_27514311 0.309 NM_020124
IFNK
interferon, kappa
chrX_-_138552517 0.309 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr19_-_19793512 0.309 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr2_-_157890400 0.308 NM_020711
ERMN
ermin, ERM-like protein
chr1_-_24112345 0.308 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr6_-_44341296 0.308 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_-_42742729 0.307 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr12_+_47584159 0.307 NM_033124
CCDC65
coiled-coil domain containing 65
chr18_+_59726183 0.304 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_84382575 0.303 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_-_11614279 0.302 NM_001080491
USP6NL
USP6 N-terminal like
chr10_+_8137356 0.297 GATA3
GATA binding protein 3
chr1_+_32512298 0.297 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr22_+_23753940 0.295 NM_001145206
KIAA1671
KIAA1671
chr6_-_136889302 0.294 MAP7
microtubule-associated protein 7
chr2_+_64534774 0.294 NM_014181
HSPC159
galectin-related protein
chr3_-_9265592 0.293 SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr11_+_112763722 0.292 NM_178510
ANKK1
ankyrin repeat and kinase domain containing 1
chr1_+_190811479 0.292 NM_002922
RGS1
regulator of G-protein signaling 1
chr2_-_218739891 0.290 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 5.21e-03 GO:0002376 immune system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 3.20e-03 GO:0071944 cell periphery
1.15 4.39e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.25 1.44e-02 GO:0004872 receptor activity
1.22 1.82e-02 GO:0004871 signal transducer activity
1.22 1.82e-02 GO:0060089 molecular transducer activity