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Motif ID: KLF12.p2

Z-value: 2.743

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_79855580	2.545		LIN7A	lin-7 homolog A (C. elegans)
chr12_-_79855618	2.436	NM_004664	LIN7A	lin-7 homolog A (C. elegans)
chr15_+_38550451	2.151	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr1_+_168899936	2.041	NM_006902 NM_022716	PRRX1	paired related homeobox 1
chr9_+_136673464	1.880	NM_000093	COL5A1	collagen, type V, alpha 1
chr10_+_94439658	1.780	NM_002729	HHEX	hematopoietically expressed homeobox
chr11_-_65841077	1.759	NM_020404	CD248	CD248 molecule, endosialin
chr16_-_66535923	1.747		SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4
chr2_+_85834111	1.667	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr9_+_136673534	1.490		COL5A1	collagen, type V, alpha 1
chr19_-_14121728	1.450		LPHN1	latrophilin 1
chr20_+_8060762	1.430	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr11_-_118716244	1.414		MFRP	membrane frizzled-related protein
chr16_-_66535457	1.333	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr2_-_25328452	1.308	NM_153759	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chr4_+_2783764	1.263		SH3BP2	SH3-domain binding protein 2
chr9_+_139292094	1.261	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr5_-_81082614	1.249		SSBP2	single-stranded DNA binding protein 2
chr2_-_220144254	1.243		OBSL1	obscurin-like 1
chr8_+_40130143	1.222	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr17_-_35331435	1.186		ORMDL3	ORM1-like 3 (S. cerevisiae)
chr11_+_1607580	1.157	NM_001001480	KRTAP5-5	keratin associated protein 5-5
chr7_+_149699185	1.135	NM_014374	REPIN1	replication initiator 1
chr1_+_26671488	1.132	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr16_+_2503915	1.122		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr10_-_105410840	1.110
chr17_+_35853177	1.110	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr12_+_119900931	1.104	NM_000545	HNF1A	HNF1 homeobox A
chr20_+_34603311	1.098		MYL9	myosin, light chain 9, regulatory
chr16_+_2503676	1.094	NM_001198569 NM_001694	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_-_1495742	1.083	NM_003693 NM_145350 NM_145352	SCARF1	scavenger receptor class F, member 1
chr3_-_130761967	1.075		PLXND1	plexin D1
chr11_+_65164767	1.068		SIPA1	signal-induced proliferation-associated 1
chr1_+_26895108	1.062	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr3_-_129690056	1.059	NM_001145661	GATA2	GATA binding protein 2
chr17_-_44026042	1.056	NM_002147	HOXB5	homeobox B5
chr5_-_149515331	1.048		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr17_-_38081967	1.045	NM_024927	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr11_+_65164963	1.025
chr16_+_82490230	1.007	NM_012213	MLYCD	malonyl-CoA decarboxylase
chr19_-_19487237	1.006	NM_032037	TSSK6	testis-specific serine kinase 6
chr16_+_27320983	0.997	NM_181078 NM_181079	IL21R	interleukin 21 receptor
chr12_+_119900677	0.984		HNF1A	HNF1 homeobox A
chr20_+_34206070	0.983	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr18_+_30810889	0.977	NM_001143826	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr13_-_110365336	0.977		ANKRD10	ankyrin repeat domain 10
chr8_-_145132582	0.970	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr6_+_11646472	0.967	NM_001100829	TMEM170B	transmembrane protein 170B
chr5_+_88220846	0.959
chr1_-_92724181	0.948	NM_001127216	GFI1	growth factor independent 1 transcription repressor
chr7_-_135083906	0.938	NM_205855	FAM180A	family with sequence similarity 180, member A
chr9_-_138387903	0.929		CARD9	caspase recruitment domain family, member 9
chr5_+_137716169	0.927	NM_016604	KDM3B	lysine (K)-specific demethylase 3B
chr17_-_44026321	0.924		HOXB5	homeobox B5
chr2_+_185171480	0.910		ZNF804A	zinc finger protein 804A
chr19_+_43572679	0.908	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr19_+_40322231	0.902	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr9_-_138387926	0.899	NM_052813 NM_052814	CARD9	caspase recruitment domain family, member 9
chr2_-_188127294	0.897		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr17_+_44643067	0.891		ABI3	ABI family, member 3
chr5_+_155686333	0.889	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr9_+_135232937	0.883		C9orf96	chromosome 9 open reading frame 96
chr2_+_185171537	0.879		ZNF804A	zinc finger protein 804A
chr2_+_185171682	0.875		ZNF804A	zinc finger protein 804A
chr5_+_34692239	0.874		RAI14	retinoic acid induced 14
chr17_-_34084682	0.872	NM_001130677	C17orf96	chromosome 17 open reading frame 96
chr3_+_49033621	0.872	NM_199073	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr5_-_176868483	0.864		DOK3	docking protein 3
chr1_-_32479785	0.863		MTMR9LP	myotubularin related protein 9-like, pseudogene
chr6_+_116939500	0.862	NM_153711	FAM26E	family with sequence similarity 26, member E
chr6_+_17708483	0.854	NM_016255	FAM8A1	family with sequence similarity 8, member A1
chr5_-_81082699	0.853	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr17_+_1612092	0.846		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_56135353	0.845	NM_031479	INHBE	inhibin, beta E
chr5_+_88221013	0.828		RPS6	ribosomal protein S6
chr17_-_16197549	0.823		CENPV	centromere protein V
chr2_-_219791638	0.818		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_16247870	0.811	NM_001165945	CLCNKB	chloride channel Kb
chr6_-_11490487	0.804	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr16_-_30301357	0.794		SEPT1	septin 1
chr2_-_188127430	0.793	NM_001032281 NM_006287	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr17_+_1612031	0.781		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_-_25390266	0.781		DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_+_43127628	0.780	NM_014726	TBKBP1	TBK1 binding protein 1
chr17_-_71352090	0.778		UNC13D	unc-13 homolog D (C. elegans)
chr5_+_34692124	0.775	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr2_-_220144427	0.775		OBSL1	obscurin-like 1
chr15_+_87432384	0.774	NM_007011 NM_152924	ABHD2	abhydrolase domain containing 2
chr2_+_169367345	0.771	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr5_-_176857158	0.769		PDLIM7	PDZ and LIM domain 7 (enigma)
chr2_-_220144511	0.765	NM_001173408 NM_001173431 NM_015311	OBSL1	obscurin-like 1
chr17_-_45620911	0.765		COL1A1	collagen, type I, alpha 1
chr11_+_116575249	0.762	NM_001001522 NM_003186	TAGLN	transgelin
chr19_-_50688310	0.762	NM_206901	RTN2	reticulon 2
chr3_-_52542748	0.759	NM_001134231	NT5DC2	5'-nucleotidase domain containing 2
chr9_-_138880530	0.758	NM_003792 NM_153200	EDF1	endothelial differentiation-related factor 1
chr7_+_37926943	0.749		EPDR1	ependymin related protein 1 (zebrafish)
chr11_-_118716736	0.749		C1QTNF5 MFRP	C1q and tumor necrosis factor related protein 5 membrane frizzled-related protein
chr6_-_166716353	0.747		BRP44L	brain protein 44-like
chr20_+_34603290	0.744	NM_006097 NM_181526	MYL9	myosin, light chain 9, regulatory
chr16_+_2503994	0.741		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr3_-_188492163	0.735	NM_001031849 NM_001879 NM_139125	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr2_+_232281491	0.734		PTMA	prothymosin, alpha
chr20_-_1113116	0.731	NM_018354	C20orf46	chromosome 20 open reading frame 46
chr10_+_76256305	0.728	NM_012330	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4
chr16_+_2503978	0.728		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr2_-_219791902	0.728	NM_005689	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_244954153	0.724		SCCPDH	saccharopine dehydrogenase (putative)
chr3_+_195888701	0.721		FAM43A	family with sequence similarity 43, member A
chr7_-_75461814	0.720		TMEM120A	transmembrane protein 120A
chr1_+_6767968	0.719	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr11_-_110755112	0.714		POU2AF1	POU class 2 associating factor 1
chr17_+_1612056	0.709		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_104394185	0.706	NM_030912	TRIM8	tripartite motif containing 8
chr19_+_50963484	0.704
chr14_+_74964261	0.700	NM_001135047	JDP2	Jun dimerization protein 2
chr3_+_49034050	0.697	NM_199069 NM_199070	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr16_-_31427130	0.693	NM_022744	C16orf58	chromosome 16 open reading frame 58
chr6_-_110843432	0.692	NM_003649 NM_004032	DDO	D-aspartate oxidase
chr13_-_110365416	0.692	NM_017664	ANKRD10	ankyrin repeat domain 10
chr17_+_35751796	0.689	NM_001024809	RARA	retinoic acid receptor, alpha
chr2_+_42128521	0.687	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr17_-_1342700	0.685	NM_001080779	MYO1C	myosin IC
chr17_-_1029758	0.681	NM_021962	ABR	active BCR-related gene
chr5_+_133870175	0.679
chr22_+_18499354	0.678	NM_001185024 NM_013373	ZDHHC8	zinc finger, DHHC-type containing 8
chr19_-_51081147	0.677	NM_015649	IRF2BP1	interferon regulatory factor 2 binding protein 1
chr3_+_52543023	0.676
chr17_-_59273988	0.673		SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr17_+_23723180	0.672		SARM1	sterile alpha and TIR motif containing 1
chr3_-_129689394	0.671	NM_001145662	GATA2	GATA binding protein 2
chr7_-_75461868	0.669		TMEM120A	transmembrane protein 120A
chr20_-_2769245	0.668	NM_022760	FAM113A	family with sequence similarity 113, member A
chr20_+_2769338	0.668	NM_022575 NM_080413	VPS16	vacuolar protein sorting 16 homolog (S. cerevisiae)
chr11_-_70971556	0.660	NM_001005405	KRTAP5-11	keratin associated protein 5-11
chr17_-_36451189	0.660	NM_030967	KRTAP1-3 KRTAP1-1	keratin associated protein 1-3 keratin associated protein 1-1
chr19_-_11169457	0.658		KANK2	KN motif and ankyrin repeat domains 2
chr22_-_41372620	0.657		CYB5R3	cytochrome b5 reductase 3
chr5_-_176857207	0.653	NM_005451 NM_203352 NM_213636	PDLIM7	PDZ and LIM domain 7 (enigma)
chr17_-_1336073	0.651		MYO1C	myosin IC
chr13_-_27967215	0.651	NM_001159920 NM_001160030 NM_001160031 NM_002019	FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
chr17_+_23723220	0.648		SARM1	sterile alpha and TIR motif containing 1
chr11_+_67563030	0.644	NM_006019	TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr17_+_23723113	0.642	NM_015077	SARM1	sterile alpha and TIR motif containing 1
chr3_-_185578621	0.641	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr17_-_71352017	0.640		UNC13D	unc-13 homolog D (C. elegans)
chr17_-_44642934	0.640	NM_001198754	GNGT2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_-_182273451	0.636	NM_015101	GLT25D2	glycosyltransferase 25 domain containing 2
chr20_-_2769120	0.634		FAM113A	family with sequence similarity 113, member A
chr2_-_73152323	0.634	NM_144579	SFXN5	sideroflexin 5
chr20_-_2769789	0.631		FAM113A	family with sequence similarity 113, member A
chr9_+_135233047	0.624	NM_153710	C9orf96	chromosome 9 open reading frame 96
chr19_-_3928516	0.622		EEF2	eukaryotic translation elongation factor 2
chr3_+_171619346	0.621	NM_005602	CLDN11	claudin 11
chr6_-_111911106	0.616	NM_002912	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr1_+_1994943	0.615	NM_001033581	PRKCZ	protein kinase C, zeta
chr10_-_44200458	0.615	NM_000609 NM_001033886 NM_001178134 NM_199168	CXCL12	chemokine (C-X-C motif) ligand 12
chr14_-_22891263	0.612	NM_020372	SLC22A17	solute carrier family 22, member 17
chr11_-_118471313	0.611		H2AFX	H2A histone family, member X
chr6_+_32003380	0.610		C2	complement component 2
chr7_-_99871981	0.608	NM_145030	C7orf47	chromosome 7 open reading frame 47
chr14_-_22358752	0.607	NM_001126106	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr15_-_80123935	0.606		MEX3B	mex-3 homolog B (C. elegans)
chr6_+_19945578	0.605	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr16_-_30301634	0.605	NM_052838	SEPT1	septin 1
chr4_+_72271218	0.602	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chrX_-_154146930	0.602	NM_171998	RAB39B	RAB39B, member RAS oncogene family
chr7_+_23496661	0.601		RPS2P32	ribosomal protein S2 pseudogene 32
chr5_+_34692352	0.600	NM_001145520	RAI14	retinoic acid induced 14
chr5_-_176869463	0.600	NM_024872	DOK3	docking protein 3
chr17_-_59131194	0.599		LIMD2	LIM domain containing 2
chr17_-_59131210	0.592	NM_030576	LIMD2	LIM domain containing 2
chr16_+_65756179	0.590		HSF4	heat shock transcription factor 4
chr1_+_149286796	0.589	NM_017860	C1orf56	chromosome 1 open reading frame 56
chr10_+_111755715	0.583	NM_019903	ADD3	adducin 3 (gamma)
chr15_+_62230962	0.582	NM_024798	SNX22	sorting nexin 22
chr17_-_71352182	0.581	NM_199242	UNC13D	unc-13 homolog D (C. elegans)
chr15_-_72952648	0.581	NM_005697	SCAMP2	secretory carrier membrane protein 2
chr5_-_32480586	0.580	NM_016107	ZFR	zinc finger RNA binding protein
chr5_-_176869943	0.578	NM_001144875 NM_001144876	DOK3	docking protein 3
chr7_+_90177082	0.578		CDK14	cyclin-dependent kinase 14
chr1_+_26220895	0.578		EXTL1	exostoses (multiple)-like 1
chr10_-_102269580	0.576	NM_015490	SEC31B	SEC31 homolog B (S. cerevisiae)
chr8_-_145119627	0.576	NM_201378	PLEC	plectin
chr1_-_182273114	0.576		GLT25D2	glycosyltransferase 25 domain containing 2
chr16_+_66129481	0.573		FAM65A	family with sequence similarity 65, member A
chr9_-_90983501	0.573	NM_016848	SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr5_-_32480486	0.570		ZFR	zinc finger RNA binding protein
chr1_-_42978320	0.570	NM_001123395 NM_001185117 NM_148960	CLDN19	claudin 19
chr17_+_12633504	0.570	NM_014859	ARHGAP44	Rho GTPase activating protein 44
chr19_+_47521600	0.567	NM_001410	MEGF8	multiple EGF-like-domains 8
chr1_-_53380709	0.567	NM_006671	SLC1A7	solute carrier family 1 (glutamate transporter), member 7
chr2_+_232281470	0.567	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr16_+_31132842	0.566	NM_001008274	TRIM72	tripartite motif containing 72
chr19_+_10689772	0.565		DNM2	dynamin 2
chr17_+_71772875	0.564	NM_182565	FAM100B	family with sequence similarity 100, member B
chr6_-_166716449	0.564	NM_016098	BRP44L	brain protein 44-like
chr6_-_109882116	0.562		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr3_-_121883647	0.562		HGD	homogentisate 1,2-dioxygenase
chr19_+_6723705	0.561	NM_005428	VAV1	vav 1 guanine nucleotide exchange factor

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	2.64e-07	GO:0065007	biological regulation
1.10	1.51e-06	GO:0050789	regulation of biological process
1.10	7.08e-06	GO:0050794	regulation of cellular process
1.19	1.30e-05	GO:0048518	positive regulation of biological process
1.22	3.33e-05	GO:0048523	negative regulation of cellular process
1.20	4.12e-05	GO:0048519	negative regulation of biological process
1.15	4.32e-05	GO:0023052	signaling
1.26	7.53e-05	GO:0007399	nervous system development
1.14	2.24e-04	GO:0032502	developmental process
1.15	2.93e-04	GO:0007275	multicellular organismal development
1.20	3.47e-04	GO:0065008	regulation of biological quality
1.26	7.24e-04	GO:0051239	regulation of multicellular organismal process
1.21	8.93e-04	GO:0048583	regulation of response to stimulus
1.16	1.74e-03	GO:0048731	system development
1.15	1.89e-03	GO:0048856	anatomical structure development
1.05	1.99e-03	GO:0009987	cellular process
1.19	2.18e-03	GO:0030154	cell differentiation
1.17	2.34e-03	GO:0048522	positive regulation of cellular process
1.14	2.38e-03	GO:0007165	signal transduction
1.28	3.11e-03	GO:0032879	regulation of localization
1.28	4.08e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.40	5.23e-03	GO:0019226	transmission of nerve impulse
1.40	5.23e-03	GO:0035637	multicellular organismal signaling
1.18	5.25e-03	GO:0048869	cellular developmental process
1.35	7.69e-03	GO:0010629	negative regulation of gene expression
1.19	9.91e-03	GO:0007166	cell surface receptor linked signaling pathway
1.16	1.09e-02	GO:0010468	regulation of gene expression
1.36	1.91e-02	GO:0051253	negative regulation of RNA metabolic process
1.25	2.07e-02	GO:0010646	regulation of cell communication
1.10	2.11e-02	GO:0032501	multicellular organismal process
1.16	2.75e-02	GO:0051252	regulation of RNA metabolic process
1.27	2.79e-02	GO:0050793	regulation of developmental process
1.35	3.10e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.30	3.70e-02	GO:0051049	regulation of transport
1.19	3.93e-02	GO:0023051	regulation of signaling
1.25	3.95e-02	GO:0007154	cell communication
1.29	3.97e-02	GO:2000026	regulation of multicellular organismal development
1.30	4.48e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.32	4.63e-02	GO:0051172	negative regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.19	1.58e-05	GO:0033267	axon part
1.63	1.49e-03	GO:0030424	axon
2.36	1.74e-03	GO:0044306	neuron projection terminus
1.41	2.13e-03	GO:0043005	neuron projection
2.80	2.37e-03	GO:0043195	terminal button
2.28	9.74e-03	GO:0043679	axon terminus
1.55	1.16e-02	GO:0030425	dendrite
1.25	1.91e-02	GO:0005626	insoluble fraction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.09	2.70e-05	GO:0005515	protein binding
1.31	3.74e-05	GO:0001071	nucleic acid binding transcription factor activity
1.31	3.74e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.37	4.12e-05	GO:0043565	sequence-specific DNA binding
1.28	2.89e-04	GO:0030528	transcription regulator activity