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Motif ID: PBX1.p2

Z-value: 1.502

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_27108826	3.777	NM_006735	HOXA2	homeobox A2
chr13_-_32757835	3.274	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr2_-_189752575	3.045	NM_000393	COL5A2	collagen, type V, alpha 2
chr5_+_3649167	3.041	NM_024337	IRX1	iroquois homeobox 1
chr18_+_42780784	2.983	NM_031303	KATNAL2	katanin p60 subunit A-like 2
chr1_+_24518501	2.921	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr1_+_24518398	2.609	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr3_-_113495763	2.487	NM_183061	SLC9A10	solute carrier family 9, member 10
chr12_+_77782719	2.455		SYT1	synaptotagmin I
chr6_-_166960690	2.360	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_+_113671744	2.351	NM_006169	NNMT	nicotinamide N-methyltransferase
chr6_-_166960649	2.257		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_+_51025604	2.088	NM_001042481	FRMD6	FERM domain containing 6
chr5_-_58607673	2.086	NM_001197220	PDE4D	phosphodiesterase 4D, cAMP-specific
chr12_-_28016182	2.063	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr21_+_29439768	1.891		C21orf7	chromosome 21 open reading frame 7
chr3_+_157877146	1.853	NM_001184718	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr6_-_166960496	1.834		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_-_177950658	1.798	NM_005429	VEGFC	vascular endothelial growth factor C
chr1_+_162795328	1.774	NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr3_+_195336625	1.762	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr19_+_13767207	1.739	NM_023072	ZSWIM4	zinc finger, SWIM-type containing 4
chr13_-_109236897	1.714	NM_003749	IRS2	insulin receptor substrate 2
chr18_+_45342398	1.699	NM_006033	LIPG	lipase, endothelial
chr3_+_195336631	1.646		HES1	hairy and enhancer of split 1, (Drosophila)
chr22_-_28972683	1.627	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr6_-_26125939	1.542	NM_005325	HIST1H1A	histone cluster 1, H1a
chrX_-_10548458	1.539	NM_000381 NM_033289	MID1	midline 1 (Opitz/BBB syndrome)
chr3_-_21767819	1.537	NM_024697	ZNF385D	zinc finger protein 385D
chr5_-_171814026	1.529	NM_001017995	SH3PXD2B	SH3 and PX domains 2B
chr14_-_75196911	1.491		C14orf1	chromosome 14 open reading frame 1
chr9_-_83494198	1.440		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr13_+_94052022	1.426	NM_180989	GPR180	G protein-coupled receptor 180
chr21_-_35174742	1.420		RUNX1	runt-related transcription factor 1
chr2_+_12774264	1.342	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chr6_-_26379567	1.339	NM_003534	HIST1H3G	histone cluster 1, H3g
chr14_+_75197303	1.251	NM_015072	TTLL5	tubulin tyrosine ligase-like family, member 5
chr16_+_81218074	1.234	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr4_+_87734489	1.143	NM_006264 NM_080683 NM_080684 NM_080685	PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr5_-_171813960	1.126		SH3PXD2B	SH3 and PX domains 2B
chr20_-_45848043	1.111	NM_018837	SULF2	sulfatase 2
chr14_+_75197345	1.103		TTLL5	tubulin tyrosine ligase-like family, member 5
chr14_+_75197409	1.094		TTLL5	tubulin tyrosine ligase-like family, member 5
chr14_+_54104383	1.094	NM_001161576 NM_015589	SAMD4A	sterile alpha motif domain containing 4A
chr1_-_147665783	1.065		HIST2H2BF	histone cluster 2, H2bf
chr15_+_39032927	1.058	NM_001142776 NM_024111	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)
chr8_-_49996353	1.041	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr4_+_86968069	1.040		ARHGAP24	Rho GTPase activating protein 24
chr3_+_173951163	1.034		ECT2	epithelial cell transforming sequence 2 oncogene
chr4_-_186537145	1.025	NM_018409	LRP2BP	LRP2 binding protein
chr16_+_81218142	1.010		CDH13	cadherin 13, H-cadherin (heart)
chr2_+_218843358	0.960	NM_001077399 NM_015488	PNKD	paroxysmal nonkinesigenic dyskinesia
chrX_-_15263596	0.950	NM_002641 NM_020473	PIGA	phosphatidylinositol glycan anchor biosynthesis, class A
chrX_+_46581418	0.931		RP2	retinitis pigmentosa 2 (X-linked recessive)
chr1_-_219982081	0.930	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr11_+_13646727	0.925	NM_032228	FAR1	fatty acyl CoA reductase 1
chr10_+_99390459	0.924		PI4K2A	phosphatidylinositol 4-kinase type 2 alpha
chr3_+_185762233	0.918	NM_004443	EPHB3	EPH receptor B3
chrX_-_15263586	0.910		PIGA	phosphatidylinositol glycan anchor biosynthesis, class A
chr1_-_219982049	0.903		DUSP10	dual specificity phosphatase 10
chrX_-_15263555	0.887		PIGA	phosphatidylinositol glycan anchor biosynthesis, class A
chr17_+_8132539	0.849	NM_001177801 NM_001177802 NM_016492	RANGRF	RAN guanine nucleotide release factor
chr3_+_138132006	0.847	NM_001190796	NCK1	NCK adaptor protein 1
chr6_-_32892705	0.845	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr3_-_71196696	0.844		FOXP1	forkhead box P1
chrX_+_46581368	0.831		RP2	retinitis pigmentosa 2 (X-linked recessive)
chr11_+_13646839	0.830		FAR1	fatty acyl CoA reductase 1
chr11_+_13646822	0.822		FAR1	fatty acyl CoA reductase 1
chr1_-_219982016	0.822		DUSP10	dual specificity phosphatase 10
chr12_+_21059896	0.820	NM_001009562	LST-3TM12	organic anion transporter LST-3b
chr12_+_77782648	0.801		SYT1	synaptotagmin I
chr22_-_37520049	0.797		DNAL4	dynein, axonemal, light chain 4
chr6_-_46728188	0.792	NM_016593	CYP39A1	cytochrome P450, family 39, subfamily A, polypeptide 1
chr4_-_140696740	0.792	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr7_-_7646573	0.788		RPA3	replication protein A3, 14kDa
chr12_-_54409710	0.788		CD63	CD63 molecule
chr13_+_96726197	0.780		MBNL2	muscleblind-like 2 (Drosophila)
chr3_+_161040439	0.766		SCHIP1	schwannomin interacting protein 1
chr20_+_43874735	0.763		UBE2C	ubiquitin-conjugating enzyme E2C
chr5_-_94442941	0.763		MCTP1	multiple C2 domains, transmembrane 1
chrX_+_46581290	0.762	NM_006915	RP2	retinitis pigmentosa 2 (X-linked recessive)
chr7_+_7646840	0.761		LOC729852	hypothetical LOC729852
chr14_+_73621408	0.758	NM_001024674	LIN52	lin-52 homolog (C. elegans)
chr16_-_3433490	0.755	NM_152457	ZNF597	zinc finger protein 597
chr9_-_14303509	0.745		NFIB	nuclear factor I/B
chr10_+_13182061	0.729	NM_001008211 NM_001008212 NM_001008213 NM_021980	OPTN	optineurin
chr14_+_99220349	0.726	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr4_+_81325447	0.722	NM_020226	PRDM8	PR domain containing 8
chr3_+_161040343	0.718	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr14_-_91642703	0.712	NM_001127696 NM_001127697 NM_001164774 NM_001164776 NM_001164777 NM_001164778 NM_001164779 NM_001164780 NM_001164781 NM_001164782 NM_004993 NM_030660	ATXN3	ataxin 3
chr2_+_28469850	0.707		FOSL2	FOS-like antigen 2
chr7_-_121571472	0.689	NM_005763	AASS	aminoadipate-semialdehyde synthase
chr13_+_78953258	0.681	NM_001161407 NM_019080	NDFIP2	Nedd4 family interacting protein 2
chr11_-_56951628	0.678	NM_017611	SLC43A3	solute carrier family 43, member 3
chr19_-_63092099	0.647	NM_001144989	ZNF814	zinc finger protein 814
chr11_+_122258600	0.646	NM_024806 NM_199124	C11orf63	chromosome 11 open reading frame 63
chr21_-_31012965	0.641	NM_001164435	KRTAP21-3	keratin associated protein 21-3
chr10_+_17310263	0.639	NM_003380	VIM	vimentin
chr7_+_106596641	0.637	NM_012257	HBP1	HMG-box transcription factor 1
chr20_+_56369012	0.636
chr1_-_149586341	0.634	NM_000449 NM_001025603	RFX5	regulatory factor X, 5 (influences HLA class II expression)
chr12_-_14982708	0.633	NM_152321	ERP27	endoplasmic reticulum protein 27
chr16_+_3433606	0.633	NM_001083601	NAT15	N-acetyltransferase 15 (GCN5-related, putative)
chr6_+_26153590	0.621	NM_003531	HIST1H3C	histone cluster 1, H3c
chr2_+_191454157	0.617		GLS	glutaminase
chr1_-_205272619	0.614	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr11_+_13646806	0.606		FAR1	fatty acyl CoA reductase 1
chr4_-_118226119	0.604	NM_152402	TRAM1L1	translocation associated membrane protein 1-like 1
chr3_-_191322919	0.602	NM_001134418	LEPREL1	leprecan-like 1
chr17_+_70495318	0.596	NM_014603	CDR2L	cerebellar degeneration-related protein 2-like
chr2_-_162808123	0.594	NM_004460	FAP	fibroblast activation protein, alpha
chr6_+_26381122	0.589	NM_003525	HIST1H2BI	histone cluster 1, H2bi
chr6_+_26333361	0.587	NM_003532	HIST1H3E	histone cluster 1, H3e
chr17_+_72380323	0.577	NM_198955	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr5_-_171643247	0.563		UBTD2	ubiquitin domain containing 2
chr14_-_90596665	0.555	NM_004755 NM_182398	RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr14_-_91642641	0.553		ATXN3 ATXN8	ataxin 3 ataxin 8
chr8_-_108579270	0.550	NM_001146	ANGPT1	angiopoietin 1
chr22_-_37520092	0.549	NM_005740	DNAL4	dynein, axonemal, light chain 4
chr19_-_63301386	0.547		ZSCAN18	zinc finger and SCAN domain containing 18
chr22_-_41741073	0.533		PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chrX_-_107568211	0.531	NM_033641	COL4A6	collagen, type IV, alpha 6
chr22_-_41741100	0.521	NM_001184970	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr22_+_28164571	0.515	NM_021026	RFPL1	ret finger protein-like 1
chr4_-_48477038	0.514	NM_015030	FRYL	FRY-like
chr1_+_85300580	0.509	NM_145172	WDR63	WD repeat domain 63
chr8_+_107807415	0.508	NM_001198534 NM_001198535	OXR1	oxidation resistance 1
chr20_+_43874654	0.505	NM_007019 NM_181799 NM_181800 NM_181802 NM_181803	UBE2C	ubiquitin-conjugating enzyme E2C
chr1_-_149586298	0.503		RFX5	regulatory factor X, 5 (influences HLA class II expression)
chr4_-_48477021	0.499		FRYL	FRY-like
chr3_+_130641840	0.498		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr7_+_29569913	0.489	NM_175887	PRR15	proline rich 15
chr12_+_52689062	0.487	NM_022658	HOXC8	homeobox C8
chr12_+_27568311	0.486	NM_001198915 NM_001198916 NM_003622 NM_177444	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr19_-_44573468	0.485	NM_019088	PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr9_+_112470871	0.483	NM_001166280 NM_001166281 NM_005592	MUSK	muscle, skeletal, receptor tyrosine kinase
chr1_-_159257486	0.479		F11R	F11 receptor
chr19_+_16157198	0.472	NM_014077	FAM32A	family with sequence similarity 32, member A
chr14_-_73620912	0.470	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr9_+_129604962	0.463	NM_004957	FPGS	folylpolyglutamate synthase
chr2_+_191454036	0.460		GLS	glutaminase
chr8_-_25371708	0.454		KCTD9	potassium channel tetramerisation domain containing 9
chr14_-_22722680	0.452	NM_012244	SLC7A8	solute carrier family 7 (amino acid transporter, L-type), member 8
chr12_-_51173238	0.451	NM_005554	KRT6A	keratin 6A
chr4_+_77575276	0.451	NM_020859	SHROOM3	shroom family member 3
chr12_+_28234657	0.449
chr3_-_150578023	0.449		TM4SF1	transmembrane 4 L six family member 1
chr19_+_55221023	0.448	NM_001006656 NM_015428	ZNF473	zinc finger protein 473
chr17_+_17816851	0.442	NM_001130090 NM_001130091 NM_001130092 NM_031294	LRRC48	leucine rich repeat containing 48
chr8_-_25371663	0.439		KCTD9	potassium channel tetramerisation domain containing 9
chr20_+_11846536	0.438	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr12_-_51132129	0.437	NM_005555	KRT6B	keratin 6B
chr10_+_99390431	0.436	NM_018425	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha
chr6_-_27222556	0.435	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr2_-_108972100	0.435	NM_022336	EDAR	ectodysplasin A receptor
chr3_+_130641639	0.433	NM_018262 NM_052985 NM_052989 NM_052990	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr5_-_145503190	0.432		LARS	leucyl-tRNA synthetase
chr10_+_63092724	0.432	NM_173554	C10orf107	chromosome 10 open reading frame 107
chr19_+_14501413	0.432		TECR	trans-2,3-enoyl-CoA reductase
chr14_+_23008723	0.430	NM_001042635 NM_015514	NGDN	neuroguidin, EIF4E binding protein
chr10_-_105835525	0.426		COL17A1	collagen, type XVII, alpha 1
chr15_-_84139021	0.425		KLHL25	kelch-like 25 (Drosophila)
chr11_+_6904167	0.422	NM_013250	ZNF215	zinc finger protein 215
chr5_+_86712376	0.421
chr2_+_28469864	0.420		FOSL2	FOS-like antigen 2
chr5_-_112658200	0.414		MCC	mutated in colorectal cancers
chr12_+_64982542	0.411	NM_033647	HELB	helicase (DNA) B
chr8_+_69027277	0.410		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr13_+_78953367	0.410		NDFIP2	Nedd4 family interacting protein 2
chr17_+_71174993	0.410	NM_013260	SAP30BP	SAP30 binding protein
chr19_-_55220495	0.407	NM_001025778 NM_016440	VRK3	vaccinia related kinase 3
chr6_+_46728590	0.405	NM_004277	SLC25A27	solute carrier family 25, member 27
chr4_+_8935987	0.403	NM_001105662	USP17L2 USP17L6P USP17	ubiquitin specific peptidase 17-like 2 ubiquitin specific peptidase 17-like 6 (pseudogene) ubiquitin specific peptidase 17
chr19_+_54067450	0.401	NM_014330	PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr19_+_54067491	0.400		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr19_+_54067489	0.399		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr20_-_56859352	0.398		GNAS-AS1	GNAS antisense RNA 1 (non-protein coding)
chr8_-_23768242	0.397	NM_003155	STC1	stanniocalcin 1
chr3_-_32519362	0.396	NM_017801	CMTM6	CKLF-like MARVEL transmembrane domain containing 6
chr1_+_216585298	0.390	NM_001135599 NM_003238	TGFB2	transforming growth factor, beta 2
chr10_+_63331401	0.390		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr19_-_55220439	0.388		VRK3	vaccinia related kinase 3
chrX_-_23671317	0.388	NM_001033583 NM_001037171	ACOT9	acyl-CoA thioesterase 9
chr18_+_37789187	0.387	NM_002647	PIK3C3	phosphoinositide-3-kinase, class 3
chrX_-_119550402	0.386		CUL4B	cullin 4B
chr6_+_151603201	0.384		AKAP12	A kinase (PRKA) anchor protein 12
chr3_-_52906608	0.384		TMEM110-MUSTN1	TMEM110-MUSTN1 readthrough
chr3_-_15814678	0.383	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr13_+_38159172	0.382	NM_207361	FREM2	FRAS1 related extracellular matrix protein 2
chr14_+_23008742	0.381		NGDN	neuroguidin, EIF4E binding protein
chr4_+_8940733	0.379	NM_001105662	USP17L2 USP17L6P USP17	ubiquitin specific peptidase 17-like 2 ubiquitin specific peptidase 17-like 6 (pseudogene) ubiquitin specific peptidase 17
chr19_-_63301418	0.377	NM_001145543 NM_001145544 NM_023926	ZSCAN18	zinc finger and SCAN domain containing 18
chr3_-_130641539	0.376	NM_003925	MBD4	methyl-CpG binding domain protein 4
chrX_-_92815222	0.376	NM_004538	NAP1L3	nucleosome assembly protein 1-like 3
chr3_-_52906381	0.374		TMEM110	transmembrane protein 110
chr6_+_151603346	0.374		AKAP12	A kinase (PRKA) anchor protein 12
chr19_+_44573858	0.374		MED29	mediator complex subunit 29
chr12_+_77782579	0.372	NM_005639	SYT1	synaptotagmin I
chr20_-_13567529	0.369	NM_017714	TASP1	taspase, threonine aspartase, 1
chr18_+_30427279	0.368	NM_001128175 NM_001198938 NM_001198939 NM_001198940	DTNA	dystrobrevin, alpha

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.40	2.54e-06	GO:0065004	protein-DNA complex assembly
5.11	6.57e-06	GO:0071824	protein-DNA complex subunit organization
5.56	1.17e-05	GO:0006334	nucleosome assembly
5.28	2.67e-05	GO:0031497	chromatin assembly
5.02	5.76e-05	GO:0034728	nucleosome organization
4.22	1.66e-04	GO:0006333	chromatin assembly or disassembly
4.04	1.45e-03	GO:0006323	DNA packaging
2.59	4.23e-03	GO:0034622	cellular macromolecular complex assembly
3.47	1.20e-02	GO:0071103	DNA conformation change
2.22	2.42e-02	GO:0034621	cellular macromolecular complex subunit organization
1.92	4.45e-02	GO:0071844	cellular component assembly at cellular level

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
6.38	2.02e-05	GO:0000786	nucleosome
5.02	2.33e-05	GO:0032993	protein-DNA complex
1.11	1.37e-02	GO:0005622	intracellular
1.14	1.39e-02	GO:0043229	intracellular organelle
1.11	1.61e-02	GO:0044424	intracellular part
1.14	1.67e-02	GO:0043226	organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
9.50	4.05e-02	GO:0008395	steroid hydroxylase activity