Motif ID: ETS1,2.p2

Z-value: 2.503


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS2chr21_+_39099717-0.332.1e-01Click!
ETS1chr11_-_1278972710.155.7e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_31003181 5.204 LAPTM5
lysosomal protein transmembrane 5
chr1_-_31003260 5.189 NM_006762
 LAPTM5
lysosomal protein transmembrane 5
chr10_+_49562866 4.933 WDFY4
WDFY family member 4
chr19_-_10311262 4.443 NM_002162
 ICAM3
intercellular adhesion molecule 3
chr3_-_184756101 4.400 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr16_+_29581783 4.242 NM_001030288
 SPN
sialophorin
chr7_+_50318801 3.852 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr7_-_3049872 3.849 NM_032415
 CARD11
caspase recruitment domain family, member 11
chr4_+_2783764 3.660 SH3BP2
SH3-domain binding protein 2
chr19_+_16860807 3.591 NM_003950
 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_+_16860871 3.494 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr13_-_45654327 3.494 NM_002298
 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr9_-_129707392 3.441 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_159306037 3.421 ARHGAP30
Rho GTPase activating protein 30
chr21_-_14840506 3.335 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr13_-_45654296 3.322 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_+_65152004 3.312


chr13_-_45654292 3.293 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_44985084 3.292 MYO1G
myosin IG
chr4_+_2783743 3.232 NM_001145855
 SH3BP2
SH3-domain binding protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 50 entries
enrichment   p-value GO term description
4.15 2.42e-03 GO:0050853 B cell receptor signaling pathway
2.53 1.22e-02 GO:0050864 regulation of B cell activation
2.35 8.50e-04 GO:0050851 antigen receptor-mediated signaling pathway
2.25 9.77e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.22 2.91e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.01 1.69e-04 GO:0002764 immune response-regulating signaling pathway
1.99 4.54e-04 GO:0002757 immune response-activating signal transduction
1.95 2.45e-05 GO:0030168 platelet activation
1.92 3.87e-03 GO:0051251 positive regulation of lymphocyte activation
1.91 2.78e-04 GO:0051249 regulation of lymphocyte activation
1.87 1.53e-04 GO:0045321 leukocyte activation
1.87 5.81e-03 GO:0050867 positive regulation of cell activation
1.86 7.56e-03 GO:0002696 positive regulation of leukocyte activation
1.84 3.77e-10 GO:0001775 cell activation
1.84 5.56e-04 GO:0002694 regulation of leukocyte activation
1.84 7.89e-03 GO:0046649 lymphocyte activation
1.83 3.15e-02 GO:0050863 regulation of T cell activation
1.79 1.27e-03 GO:0050865 regulation of cell activation
1.74 2.11e-02 GO:0002253 activation of immune response
1.66 1.57e-02 GO:0050778 positive regulation of immune response

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.94 2.09e-02 GO:0000932 cytoplasmic mRNA processing body
1.96 4.39e-02 GO:0005925 focal adhesion
1.91 4.83e-02 GO:0030055 cell-substrate junction
1.26 1.53e-02 GO:0005654 nucleoplasm
1.21 1.17e-02 GO:0005829 cytosol
1.11 1.82e-02 GO:0005634 nucleus
1.10 1.37e-02 GO:0044444 cytoplasmic part
1.08 2.28e-04 GO:0043226 organelle
1.08 2.47e-04 GO:0043229 intracellular organelle
1.08 3.84e-03 GO:0005737 cytoplasm
1.07 4.14e-06 GO:0044424 intracellular part
1.07 4.87e-06 GO:0005622 intracellular
1.07 4.26e-02 GO:0043227 membrane-bounded organelle
1.03 4.56e-02 GO:0044464 cell part
1.03 4.74e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.44 3.82e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.15 1.61e-09 GO:0005515 protein binding
1.06 2.63e-04 GO:0005488 binding