Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 4.300


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_39651189-0.811.3e-04Click!
HBP1chr7_+_1065966410.811.7e-04Click!
SSRP1chr11_-_568599000.476.5e-02Click!
HMGB3chrX_+_1499024150.351.8e-01Click!
HMGB2chr4_-_174491270-0.146.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_134114957 17.805 CALD1
caldesmon 1
chr7_+_134114912 17.231 CALD1
caldesmon 1
chr7_-_27186400 16.686 NM_153715
HOXA10
homeobox A10
chr6_+_12398514 16.008 NM_001168319
NM_001955
EDN1

endothelin 1

chr11_-_85107569 15.474 NM_206929
SYTL2
synaptotagmin-like 2
chr11_-_85108030 13.797 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr13_-_73605914 13.631 NM_007249
KLF12
Kruppel-like factor 12
chr16_+_85169615 12.871 NM_005250
FOXL1
forkhead box L1
chr13_-_98428244 12.738 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr5_-_111119846 12.688 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr8_-_72436519 12.380 EYA1
eyes absent homolog 1 (Drosophila)
chr13_-_73606362 11.495 KLF12
Kruppel-like factor 12
chr8_-_108579270 11.308 NM_001146
ANGPT1
angiopoietin 1
chr13_-_109757442 10.750 NM_001845
COL4A1
collagen, type IV, alpha 1
chr2_-_162808123 10.700 NM_004460
FAP
fibroblast activation protein, alpha
chr4_+_86918882 10.666 ARHGAP24
Rho GTPase activating protein 24
chr1_-_197173159 10.546 LOC100131234
familial acute myelogenous leukemia related factor
chr6_-_111995213 10.499 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr5_-_16989371 10.276 NM_012334
MYO10
myosin X
chr7_-_27171673 10.155 NM_152739
HOXA9
homeobox A9
chr5_-_16989290 9.983 MYO10
myosin X
chr2_-_56266408 9.773 LOC100129434
hypothetical LOC100129434
chr9_+_18464090 9.616 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr9_+_18464138 9.433 ADAMTSL1
ADAMTS-like 1
chr2_+_69093641 9.289 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr9_+_108665168 8.958 NM_021224
ZNF462
zinc finger protein 462
chr6_-_56824672 8.909 DST
dystonin
chr10_+_104525877 8.837 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr5_+_98132898 8.612 NM_001012761
RGMB
RGM domain family, member B
chr3_-_115825742 8.518 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_67201684 8.497 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr12_+_13240983 8.137 EMP1
epithelial membrane protein 1
chr8_-_124622434 8.091 NM_058229
FBXO32
F-box protein 32
chr10_+_86174665 8.078 FAM190B
family with sequence similarity 190, member B
chr12_+_13240987 7.983 EMP1
epithelial membrane protein 1
chr3_-_116272911 7.979 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_24606616 7.917 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr14_+_85066265 7.857 FLRT2
fibronectin leucine rich transmembrane protein 2
chr8_-_72437020 7.848 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr7_+_28692122 7.826 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr5_+_15553736 7.770 FBXL7
F-box and leucine-rich repeat protein 7
chr2_+_12775814 7.697


chr7_+_102340579 7.641 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr8_+_70567634 7.626 SULF1
sulfatase 1
chr14_+_85066207 7.623 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr8_+_70567581 7.524 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr7_+_20337249 7.379 NM_002214
ITGB8
integrin, beta 8
chr14_-_91483325 7.377 FBLN5
fibulin 5
chr15_+_47502666 7.366 NM_002009
FGF7
fibroblast growth factor 7
chr3_-_55496370 7.353 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr6_+_114285209 7.216 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr15_+_45797977 7.215 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr9_-_23816062 7.211 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_207738858 7.203 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_-_111777651 7.128 PITX2
paired-like homeodomain 2
chr2_+_33213111 6.906 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr9_-_14303509 6.879 NFIB
nuclear factor I/B
chr11_+_112337199 6.850 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr1_-_191422346 6.830 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr6_-_56824371 6.760 DST
dystonin
chr6_-_139654807 6.664 NM_153235
TXLNB
taxilin beta
chr1_+_85819004 6.642 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_+_15553539 6.631 FBXL7
F-box and leucine-rich repeat protein 7
chr7_-_27171648 6.597 HOXA9
homeobox A9
chr1_-_85816520 6.569 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_+_148593911 6.510


chr3_-_194118321 6.495 MB21D2
Mab-21 domain containing 2
chrX_+_86659370 6.483 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr6_+_130381408 6.452 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr3_-_55496607 6.449 WNT5A
wingless-type MMTV integration site family, member 5A
chr4_-_138673078 6.434 NM_019035
PCDH18
protocadherin 18
chr6_-_128883125 6.430 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr2_+_12775336 6.427 TRIB2
tribbles homolog 2 (Drosophila)
chr9_-_16717887 6.426 BNC2
basonuclin 2
chr21_-_27261276 6.417 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr8_-_72436832 6.389 EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_27171600 6.359 HOXA9
homeobox A9
chr9_-_14303899 6.318 NFIB
nuclear factor I/B
chr1_-_68470585 6.308 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr7_-_41709191 6.307 NM_002192
INHBA
inhibin, beta A
chr5_+_15553288 6.298 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr3_-_11585264 6.245 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr3_+_100840129 6.171 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chrX_-_99778340 6.155 NM_003270
TSPAN6
tetraspanin 6
chr9_+_102380156 5.866 NM_001018116
MURC
muscle-related coiled-coil protein
chr9_-_14304036 5.853 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr12_-_16649211 5.830 LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_126460511 5.779


chr3_-_150533948 5.776 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr4_+_86918870 5.722 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr5_-_83715947 5.713 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr2_-_164300758 5.684 NM_018086
FIGN
fidgetin
chr9_-_4289915 5.667 GLIS3
GLIS family zinc finger 3
chr4_+_146623405 5.599 NM_001003688
SMAD1
SMAD family member 1
chr3_-_65999548 5.583 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr5_-_146813343 5.582 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr2_-_188021117 5.562 NM_005795
CALCRL
calcitonin receptor-like
chr2_-_151052391 5.467 NM_005168
RND3
Rho family GTPase 3
chr4_-_141293572 5.460 MAML3
mastermind-like 3 (Drosophila)
chr14_+_76298693 5.414 VASH1
vasohibin 1
chr7_+_27190688 5.384


chr9_+_117955890 5.380 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr4_-_111777584 5.337 PITX2
paired-like homeodomain 2
chr7_-_83662152 5.268 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_-_62891066 5.252 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr3_-_11660395 5.250 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr4_-_101658094 5.247 NM_001159694
NM_016242
EMCN

endomucin

chrX_-_19598912 5.204 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr14_+_76297885 5.144 NM_014909
VASH1
vasohibin 1
chr18_+_3441589 5.142 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr7_-_27190882 5.116 HOXA11
homeobox A11
chrX_-_10548458 5.100 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr2_-_175578156 5.095 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr7_+_134114701 5.068 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr5_-_83716346 5.046 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr3_-_113842133 5.021 CCDC80
coiled-coil domain containing 80
chrX_-_33139349 4.970 NM_004006
DMD
dystrophin
chr18_-_21184824 4.941


chr11_+_112337299 4.926 NCAM1
neural cell adhesion molecule 1
chr11_+_112337491 4.925 NCAM1
neural cell adhesion molecule 1
chr14_-_91483757 4.913 NM_006329
FBLN5
fibulin 5
chr12_-_88270375 4.897 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr3_-_113841967 4.889 CCDC80
coiled-coil domain containing 80
chr7_+_93388951 4.847 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr6_-_134540666 4.804 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr6_+_148705421 4.794 NM_015278
SASH1
SAM and SH3 domain containing 1
chr3_-_115960807 4.768 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_-_83052606 4.767 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chrX_+_77889861 4.761 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr8_-_6407882 4.734 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr1_-_85703198 4.705 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_-_29262240 4.698 NM_057158
DUSP4
dual specificity phosphatase 4
chr11_+_131286513 4.697 NTM
neurotrimin
chr3_-_113842237 4.693 CCDC80
coiled-coil domain containing 80
chr15_-_68781662 4.596 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr3_-_113842255 4.594 CCDC80
coiled-coil domain containing 80
chr14_+_22375747 4.593 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr7_-_47588160 4.593 TNS3
tensin 3
chr3_+_174598937 4.579 NM_014932
NLGN1
neuroligin 1
chr14_+_22375753 4.515 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr7_-_47588266 4.485 TNS3
tensin 3
chr1_-_177378801 4.472 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr12_+_13240868 4.466 NM_001423
EMP1
epithelial membrane protein 1
chr11_+_131285747 4.443 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr2_+_85834111 4.439 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chrX_+_135079461 4.404 NM_001167819
FHL1
four and a half LIM domains 1
chr3_-_145049853 4.402 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr11_+_101488380 4.391 NM_001195045
YAP1
Yes-associated protein 1
chr4_-_141294682 4.373 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr13_+_110653407 4.357 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_-_95165089 4.285 NM_001839
CNN3
calponin 3, acidic
chr3_+_29297806 4.272 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr11_+_113436438 4.252 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr7_-_27108826 4.225 NM_006735
HOXA2
homeobox A2
chr1_-_224993498 4.221 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr13_-_32678142 4.208 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_+_20336849 4.179 ITGB8
integrin, beta 8
chr5_+_15553768 4.175 FBXL7
F-box and leucine-rich repeat protein 7
chr5_+_36642424 4.172 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_27153892 4.146 NM_024014
HOXA6
homeobox A6
chr2_-_152299229 4.114 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr12_-_47868563 4.110 TUBA1A
tubulin, alpha 1a
chr6_+_21774624 4.091 FLJ22536
hypothetical locus LOC401237
chr13_+_109757593 4.086 NM_001846
COL4A2
collagen, type IV, alpha 2
chr5_+_61910318 4.086 NM_181506
LRRC70
leucine rich repeat containing 70
chr3_-_194118627 4.067 NM_178496
MB21D2
Mab-21 domain containing 2
chr12_-_8706533 4.067 MFAP5
microfibrillar associated protein 5
chr4_-_7991992 4.042 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr11_+_112337411 4.036 NCAM1
neural cell adhesion molecule 1
chr1_-_199742589 4.019 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr20_+_19818209 4.005 NM_018993
RIN2
Ras and Rab interactor 2
chr5_-_121441910 3.930 NM_002317
LOX
lysyl oxidase
chr19_-_45016587 3.927 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr3_-_15814678 3.921 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr4_-_74307637 3.901 ANKRD17
ankyrin repeat domain 17
chr7_+_28415495 3.890 LOC401317
hypothetical LOC401317
chr9_+_81377289 3.881 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_-_27149750 3.872 NM_019102
HOXA5
homeobox A5
chr5_-_39400319 3.858 NM_001737
C9
complement component 9
chr15_-_81667169 3.834 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr5_-_121441866 3.819 LOX
lysyl oxidase
chr14_+_62740878 3.819 NM_020663
RHOJ
ras homolog gene family, member J
chr9_+_81377419 3.816 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_-_106846253 3.810 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr1_+_68070573 3.806


chr4_-_140696740 3.776 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chrX_+_15428820 3.775 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr4_-_152366970 3.753 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chr12_-_16650687 3.752 LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_+_13767207 3.741 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chr1_+_162795538 3.729 PBX1
pre-B-cell leukemia homeobox 1
chr12_-_16650697 3.708 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_121441805 3.702 LOX
lysyl oxidase
chr7_+_134226727 3.681 CALD1
caldesmon 1
chr13_-_32658215 3.672 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_31190505 3.666 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr15_-_53996597 3.654 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr3_+_114414064 3.602 NM_033254
BOC
Boc homolog (mouse)
chr4_-_138673014 3.590 PCDH18
protocadherin 18
chr18_-_51406359 3.583 TCF4
transcription factor 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 2.28e-14 GO:0048731 system development
1.40 1.56e-13 GO:0048856 anatomical structure development
1.37 5.32e-13 GO:0007275 multicellular organismal development
1.34 1.90e-12 GO:0032502 developmental process
1.56 2.35e-10 GO:0009653 anatomical structure morphogenesis
2.04 3.99e-10 GO:0072358 cardiovascular system development
2.04 3.99e-10 GO:0072359 circulatory system development
1.54 1.97e-09 GO:0007399 nervous system development
1.24 3.02e-09 GO:0032501 multicellular organismal process
2.26 1.55e-08 GO:0001944 vasculature development
1.74 3.03e-08 GO:0007155 cell adhesion
1.74 3.03e-08 GO:0022610 biological adhesion
2.27 6.34e-08 GO:0001568 blood vessel development
1.40 2.90e-07 GO:0030154 cell differentiation
3.36 4.40e-07 GO:0030336 negative regulation of cell migration
3.36 4.40e-07 GO:2000146 negative regulation of cell motility
1.39 5.60e-07 GO:0048869 cellular developmental process
3.21 9.27e-07 GO:0051271 negative regulation of cellular component movement
1.74 9.66e-07 GO:0007167 enzyme linked receptor protein signaling pathway
2.21 9.84e-07 GO:0030334 regulation of cell migration
2.18 1.73e-06 GO:2000145 regulation of cell motility
1.34 3.40e-06 GO:0048519 negative regulation of biological process
1.80 4.40e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.65 5.79e-06 GO:2000026 regulation of multicellular organismal development
1.36 6.02e-06 GO:0048523 negative regulation of cellular process
2.07 6.88e-06 GO:0051270 regulation of cellular component movement
2.06 9.61e-06 GO:0030029 actin filament-based process
2.96 1.08e-05 GO:0040013 negative regulation of locomotion
1.32 1.37e-05 GO:0048522 positive regulation of cellular process
2.05 1.46e-05 GO:0040012 regulation of locomotion
1.16 2.33e-05 GO:0050794 regulation of cellular process
1.15 2.64e-05 GO:0050789 regulation of biological process
2.11 3.03e-05 GO:0030036 actin cytoskeleton organization
2.53 3.28e-05 GO:0007156 homophilic cell adhesion
2.18 4.56e-05 GO:0048514 blood vessel morphogenesis
1.25 6.33e-05 GO:0007165 signal transduction
1.29 6.83e-05 GO:0048518 positive regulation of biological process
1.54 7.29e-05 GO:0022008 neurogenesis
1.23 1.06e-04 GO:0023052 signaling
1.92 1.64e-04 GO:0001501 skeletal system development
1.63 2.23e-04 GO:0032989 cellular component morphogenesis
1.52 2.32e-04 GO:0050793 regulation of developmental process
1.24 3.69e-04 GO:0016043 cellular component organization
1.13 4.00e-04 GO:0065007 biological regulation
1.91 4.44e-04 GO:0016337 cell-cell adhesion
1.63 4.78e-04 GO:0000902 cell morphogenesis
1.70 4.91e-04 GO:0000904 cell morphogenesis involved in differentiation
1.52 5.03e-04 GO:0040011 locomotion
1.39 5.06e-04 GO:0009966 regulation of signal transduction
1.51 5.70e-04 GO:0048699 generation of neurons
1.36 5.83e-04 GO:0023051 regulation of signaling
1.33 6.03e-04 GO:0048513 organ development
1.74 8.93e-04 GO:0007409 axonogenesis
1.72 1.10e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.48 1.21e-03 GO:0048468 cell development
1.71 1.21e-03 GO:0048812 neuron projection morphogenesis
1.56 1.37e-03 GO:0030182 neuron differentiation
1.22 1.41e-03 GO:0071840 cellular component organization or biogenesis
1.90 1.54e-03 GO:0061061 muscle structure development
1.60 2.44e-03 GO:0048666 neuron development
1.99 2.47e-03 GO:0048011 nerve growth factor receptor signaling pathway
2.46 2.59e-03 GO:0048736 appendage development
2.46 2.59e-03 GO:0060173 limb development
1.65 2.71e-03 GO:0048858 cell projection morphogenesis
1.38 3.23e-03 GO:0051239 regulation of multicellular organismal process
2.48 3.23e-03 GO:0035107 appendage morphogenesis
2.48 3.23e-03 GO:0035108 limb morphogenesis
1.68 3.70e-03 GO:0023057 negative regulation of signaling
1.54 3.79e-03 GO:0045595 regulation of cell differentiation
1.63 4.03e-03 GO:0032990 cell part morphogenesis
1.68 4.12e-03 GO:0010648 negative regulation of cell communication
1.70 4.50e-03 GO:0009968 negative regulation of signal transduction
1.63 5.04e-03 GO:0048585 negative regulation of response to stimulus
2.36 5.11e-03 GO:0006469 negative regulation of protein kinase activity
1.63 5.73e-03 GO:0007010 cytoskeleton organization
1.52 6.48e-03 GO:0009790 embryo development
2.98 7.00e-03 GO:0010810 regulation of cell-substrate adhesion
1.62 7.16e-03 GO:0031175 neuron projection development
1.19 8.26e-03 GO:0051716 cellular response to stimulus
1.24 1.08e-02 GO:0071842 cellular component organization at cellular level
1.42 1.14e-02 GO:0032879 regulation of localization
1.64 1.17e-02 GO:0051094 positive regulation of developmental process
1.46 1.29e-02 GO:0051128 regulation of cellular component organization
1.52 1.45e-02 GO:0030030 cell projection organization
2.06 1.48e-02 GO:0030155 regulation of cell adhesion
2.24 1.78e-02 GO:0033673 negative regulation of kinase activity
2.56 1.93e-02 GO:0048706 embryonic skeletal system development
1.13 2.05e-02 GO:0050896 response to stimulus
3.47 2.31e-02 GO:0001952 regulation of cell-matrix adhesion
4.04 2.77e-02 GO:0016339 calcium-dependent cell-cell adhesion
1.38 4.05e-02 GO:0010646 regulation of cell communication
1.59 4.06e-02 GO:0048646 anatomical structure formation involved in morphogenesis
2.01 4.70e-02 GO:0001525 angiogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.39 9.80e-06 GO:0005912 adherens junction
2.89 1.59e-05 GO:0030027 lamellipodium
1.88 4.23e-05 GO:0005578 proteinaceous extracellular matrix
2.55 7.11e-05 GO:0030055 cell-substrate junction
2.21 9.14e-05 GO:0070161 anchoring junction
1.61 9.71e-05 GO:0030054 cell junction
1.77 1.29e-04 GO:0031012 extracellular matrix
2.12 1.68e-04 GO:0031252 cell leading edge
1.19 2.26e-04 GO:0005886 plasma membrane
1.19 2.51e-04 GO:0071944 cell periphery
2.53 2.83e-04 GO:0005925 focal adhesion
1.15 7.39e-04 GO:0005634 nucleus
2.41 9.26e-04 GO:0005924 cell-substrate adherens junction
3.68 1.34e-03 GO:0042641 actomyosin
1.32 2.01e-03 GO:0005856 cytoskeleton
2.29 2.16e-03 GO:0044420 extracellular matrix part
2.16 1.08e-02 GO:0030016 myofibril
1.70 1.31e-02 GO:0015629 actin cytoskeleton
8.08 1.39e-02 GO:0071437 invadopodium
2.15 1.66e-02 GO:0044449 contractile fiber part
1.77 2.03e-02 GO:0016323 basolateral plasma membrane
3.47 2.75e-02 GO:0001725 stress fiber
2.04 3.65e-02 GO:0043292 contractile fiber

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.75 1.31e-06 GO:0008092 cytoskeletal protein binding
1.89 2.92e-05 GO:0003779 actin binding
1.14 7.85e-05 GO:0005515 protein binding
1.45 2.11e-04 GO:0030528 transcription regulator activity
1.44 6.32e-04 GO:0001071 nucleic acid binding transcription factor activity
1.44 6.32e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.51 2.60e-03 GO:0005509 calcium ion binding
2.55 1.16e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity
2.21 1.58e-02 GO:0017124 SH3 domain binding
1.06 1.77e-02 GO:0005488 binding
2.87 4.45e-02 GO:0008013 beta-catenin binding