Motif ID: NFIL3.p2

Z-value: 0.427


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIL3chr9_-_932257800.523.9e-02Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_33139349 1.042 NM_004006
DMD
dystrophin
chr12_-_123568781 0.825


chr22_-_34564611 0.799 RPL41P5
ribosomal protein L41 pseudogene 5
chr5_+_36642213 0.738 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr5_+_36642424 0.722 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_95792299 0.686 NM_000710
BDKRB1
bradykinin receptor B1
chr6_-_2785682 0.654 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr1_+_194887630 0.633 NM_000186
NM_001014975
CFH

complement factor H

chr20_-_55718982 0.630 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr2_-_192420168 0.560 NM_004657
SDPR
serum deprivation response
chr13_-_43908937 0.554 TSC22D1
TSC22 domain family, member 1
chr8_+_94999167 0.523 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_+_134114701 0.488 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr11_+_35596310 0.467 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr8_-_72436832 0.465 EYA1
eyes absent homolog 1 (Drosophila)
chr5_-_79982584 0.429 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr2_-_224611568 0.406 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_+_28692122 0.405 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr8_-_72437020 0.403 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr4_-_74307637 0.391 ANKRD17
ankyrin repeat domain 17
chr1_-_177378801 0.390 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr8_+_70567634 0.388 SULF1
sulfatase 1
chr2_+_87536174 0.385 NCRNA00152
non-protein coding RNA 152
chr4_+_146820805 0.379 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr2_-_31491102 0.377 NM_000379
XDH
xanthine dehydrogenase
chr8_+_70567581 0.362 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr2_-_31491057 0.353 XDH
xanthine dehydrogenase
chr2_+_87536106 0.349 NCRNA00152
non-protein coding RNA 152
chr1_-_177106702 0.340 NM_004673
ANGPTL1
angiopoietin-like 1
chr5_-_38592439 0.339 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr13_+_96672705 0.311 MBNL2
muscleblind-like 2 (Drosophila)
chr15_-_47042932 0.308 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr13_+_96672541 0.288 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr5_-_94442941 0.288 MCTP1
multiple C2 domains, transmembrane 1
chr18_-_35634247 0.286 LOC647946
hypothetical LOC647946
chr3_-_113842652 0.284 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr5_-_94443300 0.281 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr4_-_159311959 0.276 FAM198B
family with sequence similarity 198, member B
chr2_+_178893216 0.273 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr5_+_56507029 0.272 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr5_-_111119846 0.262 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr7_+_89681069 0.259 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr4_-_96689373 0.257 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr4_+_123873306 0.256 NM_001178007
NM_152618
BBS12

Bardet-Biedl syndrome 12

chr13_-_79810972 0.251 SPRY2
sprouty homolog 2 (Drosophila)
chr4_+_120167264 0.246 SYNPO2
synaptopodin 2
chr15_-_53996597 0.241 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr2_+_148319033 0.235 NM_001616
ACVR2A
activin A receptor, type IIA
chr3_+_23962518 0.231 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr11_-_10487212 0.226 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr4_+_3341521 0.225 NM_198227
RGS12
regulator of G-protein signaling 12
chr9_-_94338072 0.219 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr5_+_86712376 0.218


chr13_+_113546943 0.218 GAS6
growth arrest-specific 6
chr1_+_11171967 0.213 NM_021146
ANGPTL7
angiopoietin-like 7
chr16_-_69876262 0.210 FTSJD1
FtsJ methyltransferase domain containing 1
chr11_+_93394025 0.209 NM_001098672
HEPHL1
hephaestin-like 1
chr11_+_111552298 0.208 NM_001037290
BCO2
beta-carotene oxygenase 2
chr16_+_7322751 0.206 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr17_-_60439764 0.202 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr1_+_176577228 0.200 NM_004841
RASAL2
RAS protein activator like 2
chr3_+_134976965 0.197 TF
transferrin
chr6_-_28429950 0.193 NM_145909
ZNF323
zinc finger protein 323
chr7_+_142692165 0.193 NM_153345
TMEM139
transmembrane protein 139
chr9_+_17568952 0.191 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr17_-_38978772 0.190 NM_001986
ETV4
ets variant 4
chr13_+_28900776 0.187 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr3_+_42107711 0.186 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr3_+_156280604 0.183 NM_007288
MME
membrane metallo-endopeptidase
chr1_+_86785346 0.183 NM_012128
CLCA4
chloride channel accessory 4
chr17_-_59204622 0.175 CCDC47
coiled-coil domain containing 47
chr17_-_70901303 0.174 GRB2
growth factor receptor-bound protein 2
chr8_-_110689396 0.173 SYBU
syntabulin (syntaxin-interacting)
chr9_+_674193 0.170


chr4_+_110574376 0.170 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr10_+_91077581 0.166 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr14_-_66896167 0.166 NM_015994
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr4_+_170817787 0.165 CLCN3
chloride channel 3
chr2_-_98646367 0.162 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_59204685 0.159 NM_020198
CCDC47
coiled-coil domain containing 47
chr4_-_110574363 0.158 1/2-SBSRNA4
lncRNA_BC009800
chr6_+_134800533 0.155 LOC154092
hypothetical LOC154092
chr17_-_38979178 0.155 NM_001079675
ETV4
ets variant 4
chr3_+_62280435 0.151 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr3_+_152970904 0.151 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr1_+_25629968 0.150 NM_018202
TMEM57
transmembrane protein 57
chr13_-_24644304 0.150 FAM123A
family with sequence similarity 123A
chr13_+_113546912 0.145 GAS6
growth arrest-specific 6
chr11_-_123758448 0.145 NM_001005468
OR8B2
olfactory receptor, family 8, subfamily B, member 2
chr15_-_81412354 0.144 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr12_+_123339662 0.138 NM_181709
FAM101A
family with sequence similarity 101, member A
chr4_+_144477432 0.138 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr4_-_153820535 0.137 NM_152680
TMEM154
transmembrane protein 154
chr9_-_72218098 0.137 KLF9
Kruppel-like factor 9
chr10_-_102663070 0.136


chr17_-_36559579 0.136 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr14_+_101345878 0.134 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chrX_-_77037563 0.133 NM_032121
MAGT1
magnesium transporter 1
chr4_-_77147625 0.133 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr17_+_59205244 0.131


chr6_-_134415311 0.130 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr10_-_64698831 0.127 NM_004241
JMJD1C
jumonji domain containing 1C
chr11_+_4799126 0.125 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr10_+_118295417 0.125 NM_000936
PNLIP
pancreatic lipase
chr19_+_46121963 0.124 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr8_-_130868315 0.123 NM_031415
GSDMC
gasdermin C
chr1_+_195213289 0.122 NM_030787
CFHR5
complement factor H-related 5
chr17_+_36493927 0.121 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr12_-_41164052 0.120 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr4_+_111616630 0.120 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr12_-_16649211 0.118 LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_+_20294590 0.118 NM_001143828
NM_001160166
NM_021624
HRH4


histamine receptor H4


chrX_+_56772391 0.118 LOC550643
hypothetical LOC550643
chr18_+_19286784 0.118 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr16_-_53520208 0.117 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr12_+_50633430 0.117 NM_020327
ACVR1B
activin A receptor, type IB
chr9_-_72219359 0.115 NM_001206
KLF9
Kruppel-like factor 9
chr3_+_156280539 0.115 MME
membrane metallo-endopeptidase
chr13_+_96797290 0.114


chr17_+_59205289 0.112 NM_007372
NM_203499
DDX42

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

chr4_+_81325447 0.112 NM_020226
PRDM8
PR domain containing 8
chr6_+_121798443 0.110 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_74921136 0.104 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr4_+_110574420 0.102 SEC24B
SEC24 family, member B (S. cerevisiae)
chr10_+_98054074 0.099 NM_001017520
NM_004088
DNTT

deoxynucleotidyltransferase, terminal

chrX_-_131375217 0.099 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr20_+_57729659 0.097 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr19_+_46286207 0.095 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr11_+_9552809 0.095 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr1_-_109957195 0.094 NM_005272
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr4_-_153493133 0.094 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr9_-_78198867 0.094 NM_018339
RFK
riboflavin kinase
chr13_+_96726415 0.093 MBNL2
muscleblind-like 2 (Drosophila)
chr6_+_72979234 0.093 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr1_-_159474503 0.091 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr20_+_4614796 0.090 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr13_-_37070862 0.089 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr5_+_125723686 0.089 NM_001146319
GRAMD3
GRAM domain containing 3
chr11_+_111551417 0.088 NM_031938
BCO2
beta-carotene oxygenase 2
chr4_-_88669267 0.088 SPARCL1
SPARC-like 1 (hevin)
chr1_-_151614681 0.088 NM_005621
S100A12
S100 calcium binding protein A12
chr13_+_113546897 0.087 GAS6
growth arrest-specific 6
chr13_-_19008884 0.085 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr1_-_21373816 0.084 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_171838802 0.082 NM_178527
SLC9A11
solute carrier family 9, member 11
chr20_+_33223434 0.081 NM_006404
PROCR
protein C receptor, endothelial
chr11_-_62539857 0.081 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr3_+_120984246 0.080 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr1_+_57093030 0.080 NM_000562
C8A
complement component 8, alpha polypeptide
chr5_-_147996769 0.079 NM_001040169
NM_001040172
NM_001040173
NM_199453
HTR4



5-hydroxytryptamine (serotonin) receptor 4



chr5_-_56814310 0.078 NM_001017992
ACTBL2
actin, beta-like 2
chr3_+_187866464 0.078 NM_000412
HRG
histidine-rich glycoprotein
chr8_+_67568044 0.078 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr7_-_112513379 0.077 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr16_-_695719 0.076 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr7_-_83662152 0.076 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_+_73193499 0.075 NM_018029
EBLN2
endogenous Borna-like N element-2
chr5_-_75954807 0.074 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr10_-_69095362 0.074 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr20_+_36643251 0.074 NM_001018082
ADIG
adipogenin
chr3_+_44891101 0.073 NM_003241
TGM4
transglutaminase 4 (prostate)
chr17_-_36436979 0.071 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr2_-_228290942 0.070 NM_025243
SLC19A3
solute carrier family 19, member 3
chr14_+_51025604 0.070 NM_001042481
FRMD6
FERM domain containing 6
chr12_-_51360439 0.069 NM_006121
KRT1
keratin 1
chr1_-_60312013 0.068 NM_152377
C1orf87
chromosome 1 open reading frame 87
chr2_+_154436670 0.067 NM_052917
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr17_+_36515166 0.067 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr12_-_16650697 0.067 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_52441044 0.067 NM_004531
MOCS2
molybdenum cofactor synthesis 2
chr21_+_18539016 0.066 NM_024944
CHODL
chondrolectin
chr10_-_94247450 0.066 NM_001165946
IDE
insulin-degrading enzyme
chr2_-_45648608 0.066 SRBD1
S1 RNA binding domain 1
chr4_-_69218909 0.065 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr3_-_101077605 0.064 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr4_-_174774368 0.063 NM_006792
MORF4
mortality factor 4
chr1_+_33319287 0.063 NM_052998
ADC
arginine decarboxylase
chr1_+_204875374 0.063 NM_001004023
NM_003582
DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

chr6_+_153060722 0.062 NM_025107
MYCT1
myc target 1
chr3_+_44667504 0.062 ZNF35
zinc finger protein 35
chr1_+_15145001 0.061 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr22_-_15682555 0.061 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr4_-_69570919 0.061 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chrX_-_77801480 0.060 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr2_-_188127294 0.060 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr8_+_69026895 0.059 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr17_-_64649608 0.059 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr10_-_5035967 0.059 NM_001135241
AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr8_-_86441115 0.058 NM_001164830
CA1
carbonic anhydrase I
chr1_+_144236346 0.058 NM_003637
ITGA10
integrin, alpha 10
chr17_-_19592178 0.058 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr3_-_187309442 0.058 NM_004454
ETV5
ets variant 5
chr1_-_220788048 0.058 NM_024746
HHIPL2
HHIP-like 2
chr5_-_127901376 0.057 FBN2
fibrillin 2
chr3_+_103029523 0.057 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_-_16650687 0.056 LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_+_17310263 0.055 NM_003380
VIM
vimentin
chr8_-_17599438 0.055 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr22_-_27787793 0.054 NM_015370
C22orf31
chromosome 22 open reading frame 31
chrX_-_107569256 0.054 NM_001847
COL4A6
collagen, type IV, alpha 6

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.66 1.81e-03 GO:0005576 extracellular region
1.89 1.20e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
43.88 8.18e-05 GO:0047023 androsterone dehydrogenase activity
32.91 1.42e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity