Motif ID: RBPJ.p2

Z-value: 1.394


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RBPJchr4_+_259317250.476.5e-02Click!


Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_39859997 2.058


chr19_+_39860398 2.009 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr10_-_95231933 1.736 NM_013451
NM_133337
MYOF

myoferlin

chr22_+_25398690 1.606 LOC388889
hypothetical LOC388889
chr3_+_100840129 1.462 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr1_-_68470585 1.458 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr13_-_73606362 1.384 KLF12
Kruppel-like factor 12
chr2_+_159533329 1.330 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr9_+_71848555 1.329 MAMDC2
MAM domain containing 2
chr8_+_79590890 1.224 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr8_+_79591074 1.169 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chrX_+_67965517 1.168 NM_004429
EFNB1
ephrin-B1
chr21_-_31853160 1.163 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr14_-_92284626 1.150 NM_001008530
NM_005606
LGMN

legumain

chr2_-_189752575 1.145 NM_000393
COL5A2
collagen, type V, alpha 2
chr17_+_7883076 1.133 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr20_+_6696744 1.118 NM_001200
BMP2
bone morphogenetic protein 2
chr15_+_57517564 1.000 NM_152450
FAM81A
family with sequence similarity 81, member A
chr1_-_98159113 0.950 DPYD
dihydropyrimidine dehydrogenase
chr20_-_55718351 0.945 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr3_+_195336631 0.944 HES1
hairy and enhancer of split 1, (Drosophila)
chr8_+_70567634 0.941 SULF1
sulfatase 1
chr2_-_160764819 0.938 NM_000888
ITGB6
integrin, beta 6
chr10_-_92670764 0.924 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr15_+_65205107 0.854 NM_001145102
SMAD3
SMAD family member 3
chr6_+_31190505 0.839 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr10_+_115429622 0.827 CASP7
caspase 7, apoptosis-related cysteine peptidase
chr12_-_57600336 0.819 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr12_+_8741746 0.817 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr14_-_53491019 0.803 NM_130851
BMP4
bone morphogenetic protein 4
chr6_+_73388291 0.801 NM_001160130
NM_001160132
NM_001160133
NM_001160134
NM_019842
KCNQ5




potassium voltage-gated channel, KQT-like subfamily, member 5




chr8_+_70567581 0.786 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr18_-_26876622 0.770 NM_001941
NM_024423
DSC3

desmocollin 3

chr9_-_21984379 0.742 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr12_-_57600564 0.735 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr5_-_112658456 0.729 NM_002387
MCC
mutated in colorectal cancers
chr1_+_148137778 0.699 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr17_+_26322081 0.692 NM_001184992
NM_032322
NM_197939
RNF135


ring finger protein 135


chr1_+_86662356 0.681 NM_006536
CLCA2
chloride channel accessory 2
chr6_+_139055244 0.679 FLJ46906
hypothetical LOC441172
chr10_+_115429415 0.678 NM_001227
NM_033338
NM_033339
CASP7


caspase 7, apoptosis-related cysteine peptidase


chr20_+_55718718 0.667


chr2_-_160469438 0.665 LY75-CD302
LY75
LY75-CD302 read-through transcript
lymphocyte antigen 75
chr9_-_21984329 0.655 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_-_56004366 0.649 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr4_+_109033868 0.644 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr5_+_178419938 0.640 NM_014594
ZNF354C
zinc finger protein 354C
chr16_-_52877868 0.636 NM_024336
IRX3
iroquois homeobox 3
chr17_-_28228184 0.626 MYO1D
myosin ID
chr9_-_21984414 0.617 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr20_+_55718619 0.613


chr2_-_162883062 0.611 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr7_+_47661366 0.610 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr13_+_31318828 0.607 EEF1DP3
eukaryotic translation elongation factor 1 delta pseudogene 3
chr7_+_79602023 0.606 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr10_+_70517863 0.604 SRGN
serglycin
chr12_+_115481568 0.599 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr3_+_64645819 0.596 LOC100507098
hypothetical LOC100507098
chr2_-_160469512 0.592 NM_001198759
NM_001198760
NM_002349
LY75-CD302

LY75
LY75-CD302 read-through transcript

lymphocyte antigen 75
chr13_-_77391525 0.592


chr17_-_7434113 0.591 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr2_+_108637916 0.585 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr17_+_26322168 0.582 RNF135
ring finger protein 135
chr1_-_58815753 0.577 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr16_-_52877829 0.576 IRX3
iroquois homeobox 3
chr8_+_102573837 0.572 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr8_+_102574012 0.571 GRHL2
grainyhead-like 2 (Drosophila)
chr5_+_148631636 0.566 AFAP1L1
actin filament associated protein 1-like 1
chr5_+_63497408 0.558 NM_001113561
NM_178532
RNF180

ring finger protein 180

chr12_+_103133631 0.557 NM_001093771
TXNRD1
thioredoxin reductase 1
chr2_+_108637698 0.554 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_102727068 0.554 NM_001006935
NM_001006937
NM_024863
TCEAL4


transcription elongation factor A (SII)-like 4


chr5_+_148631588 0.552 NM_001146337
NM_152406
AFAP1L1

actin filament associated protein 1-like 1

chr16_-_52877467 0.551 IRX3
iroquois homeobox 3
chr2_-_160765008 0.541 ITGB6
integrin, beta 6
chr7_-_141048358 0.541 NM_001080392
KIAA1147
KIAA1147
chr19_+_58715988 0.540 NM_018555
ZNF331
zinc finger protein 331
chr19_-_41849558 0.535 NM_153257
ZNF461
zinc finger protein 461
chr13_-_77390907 0.532 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr16_+_67698943 0.531 NM_005329
HAS3
hyaluronan synthase 3
chr13_+_35904408 0.530 NM_001111045
NM_003914
CCNA1

cyclin A1

chr11_+_44543716 0.529 NM_001024844
NM_002231
CD82

CD82 molecule

chr10_+_53744043 0.522 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr17_+_8865547 0.516 NM_004822
NTN1
netrin 1
chr12_+_63958949 0.513 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr1_-_21478571 0.513 NM_001113347
ECE1
endothelin converting enzyme 1
chr2_+_85213884 0.511 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr2_+_110013297 0.510 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr12_-_83954185 0.504 NM_001100917
TSPAN19
tetraspanin 19
chr5_+_36644187 0.496 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_+_44543788 0.494 CD82
CD82 molecule
chr6_+_126112506 0.490 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr18_-_45630154 0.477 MYO5B
myosin VB
chr1_-_158948176 0.473 NM_001778
CD48
CD48 molecule
chr3_+_16191159 0.466 NM_054110
GALNTL2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr19_+_42099073 0.465 NM_198539
ZNF568
zinc finger protein 568
chr12_+_50686990 0.460 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr1_-_58815415 0.456 TACSTD2
tumor-associated calcium signal transducer 2
chrX_-_10548458 0.455 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr8_+_123863169 0.455 ZHX2
zinc fingers and homeoboxes 2
chr20_-_42249146 0.451 JPH2
junctophilin 2
chr6_+_139391511 0.446 NM_021243
C6orf115
chromosome 6 open reading frame 115
chr19_+_42033106 0.441 NM_003419
ZNF345
zinc finger protein 345
chr5_-_94443300 0.433 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr12_+_83954229 0.428 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr3_-_150858274 0.428 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr8_-_98359366 0.423 TSPYL5
TSPY-like 5
chr6_+_49626431 0.423


chr8_-_28403652 0.420 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr19_-_42098758 0.416 NM_001171979
ZNF829
zinc finger protein 829
chr1_+_216585298 0.415 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr18_+_18969724 0.412 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr11_-_6298284 0.410 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr12_-_102413875 0.409 NM_198521
NM_001099336
C12orf42

chromosome 12 open reading frame 42

chr7_-_44992729 0.408 C7orf40
chromosome 7 open reading frame 40
chr8_-_98359248 0.405 TSPYL5
TSPY-like 5
chr21_-_14677310 0.403 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr17_+_71232370 0.402 NM_001005619
ITGB4
integrin, beta 4
chr16_+_56219802 0.398 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr4_-_55686503 0.393 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chrX_+_106956158 0.389 MID2
midline 2
chr17_+_18700385 0.389 PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr3_+_42107711 0.386 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr19_+_42689881 0.384 ZNF793
zinc finger protein 793
chr11_+_66268817 0.379 C11orf80
chromosome 11 open reading frame 80
chr6_+_126112431 0.376 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr11_+_66268740 0.373 NM_024650
C11orf80
chromosome 11 open reading frame 80
chr3_+_103029523 0.370 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr3_-_145049853 0.370 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr10_+_75343352 0.370 PLAU
plasminogen activator, urokinase
chr4_-_83938920 0.368 NM_001037582
NM_024906
SCD5

stearoyl-CoA desaturase 5

chr10_-_33663984 0.368 NRP1
neuropilin 1
chr8_-_98359347 0.367 NM_033512
TSPYL5
TSPY-like 5
chr9_-_5329745 0.366 NM_006911
RLN1
relaxin 1
chr2_-_31293882 0.366 NM_001145122
CAPN14
calpain 14
chr5_+_42792676 0.363 NM_001134848
CCDC152
coiled-coil domain containing 152
chr12_-_48387233 0.361


chr4_+_146623405 0.361 NM_001003688
SMAD1
SMAD family member 1
chr12_-_93921586 0.361 NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr6_+_126112417 0.360 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr8_+_123863224 0.360 ZHX2
zinc fingers and homeoboxes 2
chr11_-_5662762 0.358 NM_033034
NM_033092
NM_033093
TRIM5


tripartite motif containing 5


chr2_+_69093641 0.356 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr6_+_49626317 0.355 C6orf141
chromosome 6 open reading frame 141
chr2_-_175255717 0.354 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr12_-_69317441 0.354 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_+_237143118 0.352 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr9_+_17124974 0.352 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr22_+_28493351 0.349 NM_001003684
NM_013387
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr3_+_160964574 0.349 SCHIP1
schwannomin interacting protein 1
chr19_+_61681294 0.347 LOC100128252
hypothetical LOC100128252
chr9_+_22436783 0.346 NM_022160
DMRTA1
DMRT-like family A1
chr19_-_42098919 0.346 NM_001037232
ZNF829
zinc finger protein 829
chr1_-_226202210 0.345 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr12_-_93921618 0.345 NM_018838
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr4_+_146622154 0.344 NM_005900
SMAD1
SMAD family member 1
chr9_+_6403321 0.341 UHRF2
ubiquitin-like with PHD and ring finger domains 2
chr19_-_55220388 0.340 VRK3
vaccinia related kinase 3
chr11_-_58102169 0.339 NM_001143995
LPXN
leupaxin
chr11_-_60885928 0.338 CYBASC3
cytochrome b, ascorbate dependent 3
chr22_-_45311730 0.337 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr3_+_49002774 0.336 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr8_-_102031943 0.333 NM_001135702
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_-_156935283 0.333


chr19_-_58449752 0.328 ZNF677
zinc finger protein 677
chr12_+_94391952 0.326 NM_006838
METAP2
methionyl aminopeptidase 2
chr11_-_60885849 0.322 CYBASC3
cytochrome b, ascorbate dependent 3
chr10_+_70517823 0.319 NM_002727
SRGN
serglycin
chr15_-_65334022 0.318 NM_024666
AAGAB
alpha- and gamma-adaptin binding protein
chr2_+_87536174 0.318 NCRNA00152
non-protein coding RNA 152
chr19_+_42689680 0.317 NM_001013659
ZNF793
zinc finger protein 793
chr14_-_59407103 0.317 NM_021136
RTN1
reticulon 1
chr13_-_40138607 0.317 NM_002015
FOXO1
forkhead box O1
chr1_+_199975563 0.315 NM_001167738
NAV1
neuron navigator 1
chr6_+_139391570 0.315 C6orf115
chromosome 6 open reading frame 115
chr14_+_51025604 0.314 NM_001042481
FRMD6
FERM domain containing 6
chr2_-_191724169 0.312 NM_003151
STAT4
signal transducer and activator of transcription 4
chr15_+_76889873 0.311 MORF4L1
mortality factor 4 like 1
chr11_-_87548199 0.309 NM_022337
RAB38
RAB38, member RAS oncogene family
chr10_-_92671005 0.309 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr5_+_14493905 0.306 TRIO
triple functional domain (PTPRF interacting)
chr7_-_19715127 0.305 NM_001002926
TWISTNB
TWIST neighbor
chr2_-_191723951 0.304 STAT4
signal transducer and activator of transcription 4
chr14_+_72773957 0.304 NM_173462
NDRG2
PAPLN
NDRG family member 2
papilin, proteoglycan-like sulfated glycoprotein
chr1_-_145699308 0.303 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chr3_+_114414064 0.303 NM_033254
BOC
Boc homolog (mouse)
chr3_+_49002285 0.297 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr12_-_48387459 0.296 NM_175736
NM_198900
FMNL3

formin-like 3

chr4_-_84475036 0.296 NM_001098540
HPSE
heparanase
chr17_+_35727998 0.295 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr14_+_72672960 0.295 PSEN1
presenilin 1
chr2_-_191723996 0.294 STAT4
signal transducer and activator of transcription 4
chr4_+_61749540 0.292 LPHN3
latrophilin 3
chr14_+_72672913 0.292 PSEN1
presenilin 1
chr5_+_94981735 0.291 NM_199243
GPR150
G protein-coupled receptor 150
chr1_-_23393808 0.290 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr4_-_84475328 0.290 NM_001166498
NM_006665
HPSE

heparanase

chr21_-_17906975 0.288 BTG3
BTG family, member 3
chr2_+_87536106 0.288 NCRNA00152
non-protein coding RNA 152
chr19_-_55220439 0.287 VRK3
vaccinia related kinase 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 9.45e-03 GO:0044424 intracellular part
1.10 3.08e-02 GO:0043226 organelle
1.09 4.61e-02 GO:0043229 intracellular organelle
1.07 4.62e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 2.38e-02 GO:0005488 binding