Motif ID: NKX3-2.p2

Z-value: 2.620


Transcription factors associated with NKX3-2.p2:

Gene SymbolEntrez IDGene Name
NKX3-2 579 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-2chr4_-_13155135-0.458.3e-02Click!


Activity profile for motif NKX3-2.p2.

activity profile for motif NKX3-2.p2


Sorted Z-values histogram for motif NKX3-2.p2

Sorted Z-values for motif NKX3-2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_17585462 6.744 VSNL1
visinin-like 1
chr2_-_70634129 5.230 NM_001099691
NM_003236
 TGFA

transforming growth factor, alpha

chr2_+_17585287 3.955 NM_003385
 VSNL1
visinin-like 1
chr10_+_24795446 3.417 KIAA1217
KIAA1217
chr11_-_119513429 3.273 TRIM29
tripartite motif containing 29
chr10_+_24795465 3.217 KIAA1217
KIAA1217
chr5_+_52812236 3.180 NM_006350
NM_013409
 FST

follistatin

chrX_-_107568211 3.027 NM_033641
 COL4A6
collagen, type IV, alpha 6
chr16_-_80602546 2.951 NM_145168
 SDR42E1
short chain dehydrogenase/reductase family 42E, member 1
chr6_+_54819527 2.950 NM_001010872
 FAM83B
family with sequence similarity 83, member B
chr20_+_51023159 2.940 TSHZ2
teashirt zinc finger homeobox 2
chr5_+_52812165 2.883 FST
follistatin
chr8_+_120289735 2.390 NM_052886
 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr11_-_119513948 2.366 TRIM29
tripartite motif containing 29
chr12_+_4253143 2.286 NM_001759
 CCND2
cyclin D2
chr11_+_66580861 2.240 NM_014578
 RHOD
ras homolog gene family, member D
chr11_-_119499188 2.192 TRIM29
tripartite motif containing 29
chr11_-_119514058 2.186 NM_012101
 TRIM29
tripartite motif containing 29
chr20_-_42249631 2.141 NM_020433
NM_175913
 JPH2

junctophilin 2

chr12_-_51200347 2.124 NM_000424
 KRT5
keratin 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.28 2.37e-02 GO:0033036 macromolecule localization
1.26 2.46e-03 GO:0010467 gene expression
1.18 3.19e-02 GO:0048518 positive regulation of biological process
1.17 1.28e-05 GO:0043170 macromolecule metabolic process
1.17 5.88e-05 GO:0044260 cellular macromolecule metabolic process
1.11 4.66e-03 GO:0044238 primary metabolic process
1.10 7.98e-03 GO:0008152 metabolic process
1.08 6.28e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.36 2.51e-02 GO:0034708 methyltransferase complex
2.36 2.51e-02 GO:0035097 histone methyltransferase complex
1.25 2.25e-02 GO:0005654 nucleoplasm
1.22 1.02e-02 GO:0031981 nuclear lumen
1.20 8.58e-03 GO:0070013 intracellular organelle lumen
1.19 1.07e-02 GO:0043233 organelle lumen
1.19 1.22e-02 GO:0031974 membrane-enclosed lumen
1.10 2.87e-05 GO:0005737 cytoplasm
1.10 1.75e-02 GO:0044444 cytoplasmic part
1.08 3.75e-03 GO:0043231 intracellular membrane-bounded organelle
1.08 5.01e-03 GO:0043227 membrane-bounded organelle
1.07 1.79e-03 GO:0043229 intracellular organelle
1.07 2.07e-03 GO:0043226 organelle
1.06 3.35e-04 GO:0005622 intracellular
1.06 4.04e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.13 1.68e-07 GO:0005515 protein binding