Motif ID: PRDM1.p3

Z-value: 2.270


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRDM1chr6_+_106653429-0.224.2e-01Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_16717887 8.062 BNC2
basonuclin 2
chr11_-_104344473 6.232 NM_001225
 CASP4
caspase 4, apoptosis-related cysteine peptidase
chr22_-_28972683 6.216 NM_002309
 LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr16_+_55580910 6.187 NM_032206
 NLRC5
NLR family, CARD domain containing 5
chr4_+_142777172 5.955 NM_000585
NM_172174
 IL15

interleukin 15

chr6_-_112682401 5.454 LAMA4
laminin, alpha 4
chr6_-_112682459 5.239 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
 LAMA4




laminin, alpha 4




chr17_+_6600080 5.089 XAF1
XIAP associated factor 1
chr3_-_115825742 4.895 NM_001164347
 ZBTB20
zinc finger and BTB domain containing 20
chr11_+_32069183 4.551 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr2_-_189752575 4.531 NM_000393
 COL5A2
collagen, type V, alpha 2
chr6_-_112682038 4.468 LAMA4
laminin, alpha 4
chr17_+_6599879 3.927 NM_017523
NM_199139
 XAF1

XIAP associated factor 1

chr6_-_112682573 3.776 LAMA4
laminin, alpha 4
chr11_-_85107569 3.737 NM_206929
 SYTL2
synaptotagmin-like 2
chr4_+_146623405 3.712 NM_001003688
 SMAD1
SMAD family member 1
chr4_+_14985272 3.239 NM_001135171
 C1QTNF7
C1q and tumor necrosis factor related protein 7
chr10_-_44200458 3.140 NM_000609
NM_001033886
NM_001178134
NM_199168
 CXCL12



chemokine (C-X-C motif) ligand 12



chr16_-_71650034 2.889 NM_001164766
 ZFHX3
zinc finger homeobox 3
chr6_-_105691235 2.851 NM_007073
 BVES
blood vessel epicardial substance

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
20.02 4.45e-02 GO:0032728 positive regulation of interferon-beta production
12.43 1.34e-06 GO:0060337 type I interferon-mediated signaling pathway
12.43 1.34e-06 GO:0071357 cellular response to type I interferon
12.24 1.60e-06 GO:0034340 response to type I interferon
10.22 6.12e-03 GO:0032479 regulation of type I interferon production
7.10 2.07e-02 GO:0043900 regulation of multi-organism process
6.84 2.73e-02 GO:0045637 regulation of myeloid cell differentiation
5.92 4.09e-04 GO:0009615 response to virus
5.72 7.97e-05 GO:0019221 cytokine-mediated signaling pathway
5.16 3.09e-04 GO:0071345 cellular response to cytokine stimulus
4.05 1.64e-04 GO:0045087 innate immune response
3.82 2.55e-02 GO:0001817 regulation of cytokine production
3.72 1.79e-02 GO:0034097 response to cytokine stimulus
3.51 3.02e-03 GO:0051707 response to other organism
3.35 3.35e-02 GO:0044419 interspecies interaction between organisms
3.18 4.26e-03 GO:0009607 response to biotic stimulus
2.95 2.45e-04 GO:0006955 immune response
2.89 4.21e-03 GO:0071310 cellular response to organic substance
2.88 1.73e-03 GO:0002682 regulation of immune system process
2.74 1.16e-03 GO:0006952 defense response

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
6.68 4.75e-02 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
21.56 5.66e-03 GO:0001530 lipopolysaccharide binding
13.35 4.33e-02 GO:0004298 threonine-type endopeptidase activity
13.35 4.33e-02 GO:0070003 threonine-type peptidase activity
4.17 1.59e-02 GO:0005126 cytokine receptor binding
2.60 2.22e-02 GO:0008233 peptidase activity
2.56 4.04e-02 GO:0070011 peptidase activity, acting on L-amino acid peptides