Motif ID: ESR1.p2

Z-value: 2.583


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESR1chr6_+_152053323-0.505.0e-02Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_29322993 3.097 NM_001003682
 TMEM200B
transmembrane protein 200B
chr18_+_75825563 3.011 NM_001136180
 HSBP1L1
heat shock factor binding protein 1-like 1
chr10_+_115428924 2.567 NM_033340
 CASP7
caspase 7, apoptosis-related cysteine peptidase
chr8_+_16929116 2.355 NM_181723
 EFHA2
EF-hand domain family, member A2
chr7_+_1543644 2.271 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr22_-_41447214 2.095 A4GALT
alpha 1,4-galactosyltransferase
chr3_-_129690056 1.929 NM_001145661
 GATA2
GATA binding protein 2
chr4_+_184257337 1.803 NM_024949
 WWC2
WW and C2 domain containing 2
chr16_-_73842884 1.780 NM_001170717
NM_014567
 BCAR1

breast cancer anti-estrogen resistance 1

chr4_+_151218862 1.743 NM_001040260
NM_001040261
 DCLK2

doublecortin-like kinase 2

chr6_+_107917965 1.713 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr17_-_30724732 1.695 NM_001104587
NM_001104588
NM_001104589
NM_001104590
NM_152270
 SLFN11




schlafen family member 11




chr9_-_83493415 1.600 NM_005077
 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chrX_+_117745551 1.583 NM_001560
 IL13RA1
interleukin 13 receptor, alpha 1
chr13_+_75108450 1.568 LMO7
LIM domain 7
chr2_+_36436316 1.555 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_+_99273751 1.502 EML1
echinoderm microtubule associated protein like 1
chr22_-_41446740 1.494 NM_017436
 A4GALT
alpha 1,4-galactosyltransferase
chr9_+_136673464 1.486 NM_000093
 COL5A1
collagen, type V, alpha 1
chr7_+_45894480 1.462 NM_000596
 IGFBP1
insulin-like growth factor binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.89 4.28e-02 GO:0030036 actin cytoskeleton organization
1.81 3.20e-02 GO:0032870 cellular response to hormone stimulus
1.48 4.38e-02 GO:0031399 regulation of protein modification process
1.13 3.88e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.71 3.86e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.50 4.44e-02 GO:0031625 ubiquitin protein ligase binding
1.79 5.00e-03 GO:0003779 actin binding
1.51 3.53e-03 GO:0019899 enzyme binding
1.19 1.60e-09 GO:0005515 protein binding
1.09 1.61e-06 GO:0005488 binding