Motif ID: SPIB.p2

Z-value: 4.186


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPIBchr19_+_556140060.766.1e-04Click!


Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_15005761 10.607 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_+_44643067 8.462 ABI3
ABI family, member 3
chr17_-_40843530 7.165 ARHGAP27
Rho GTPase activating protein 27
chr6_-_32268267 6.407 GPSM3
G-protein signaling modulator 3
chr2_-_175207521 5.936 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr17_-_44642934 5.381 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chrX_+_48427137 5.144 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr11_+_63864263 4.882 NM_032251
CCDC88B
coiled-coil domain containing 88B
chrX_+_48427103 4.834 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr6_-_11490487 4.721 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr19_+_3129735 4.644 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr19_-_40925151 4.577 NM_024660
TMEM149
transmembrane protein 149
chr14_+_99601517 4.577 EVL
Enah/Vasp-like
chr14_+_99601498 4.544 NM_016337
EVL
Enah/Vasp-like
chr7_+_128367961 4.521 NM_001098627
IRF5
interferon regulatory factor 5
chr6_-_32742265 4.499 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr17_+_37693090 4.262 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr6_-_159386007 4.243 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr6_-_32268615 4.028 GPSM3
G-protein signaling modulator 3
chr3_-_113701073 4.022 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr4_+_39874921 4.012 NM_004310
RHOH
ras homolog gene family, member H
chr2_-_225519974 3.974 DOCK10
dedicator of cytokinesis 10
chr19_-_6432765 3.781 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr1_-_205161821 3.760 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_18890963 3.743 NM_006613
GRAP
GRB2-related adaptor protein
chr18_-_65766068 3.621 CD226
CD226 molecule
chr5_+_61910318 3.556 NM_181506
LRRC70
leucine rich repeat containing 70
chr7_+_149778815 3.544 GIMAP8
GTPase, IMAP family member 8
chr5_-_169657192 3.466 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_-_120761092 3.432 NM_005191
CD80
CD80 molecule
chr16_+_30102426 3.422 CORO1A
coronin, actin binding protein, 1A
chr12_+_4253143 3.392 NM_001759
CCND2
cyclin D2
chr6_-_56824672 3.382 DST
dystonin
chr17_+_73638430 3.381 NM_152468
TMC8
transmembrane channel-like 8
chr1_-_25128951 3.373 RUNX3
runt-related transcription factor 3
chr18_-_59137488 3.366 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr5_-_138822475 3.362 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr12_+_25096755 3.331 LRMP
lymphoid-restricted membrane protein
chr1_-_25164061 3.328 NM_001031680
RUNX3
runt-related transcription factor 3
chr2_-_96174865 3.321 NM_004418
DUSP2
dual specificity phosphatase 2
chr2_+_96355661 3.317 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr7_+_149778869 3.251 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr5_-_169657312 3.218 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr4_+_91035025 3.213 NM_007351
MMRN1
multimerin 1
chr11_-_66961709 3.211 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr12_-_56157898 3.198 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr16_+_28413421 3.174 NM_018690
APOBR
apolipoprotein B receptor
chrX_-_100527799 3.158 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr5_-_169657395 3.121 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_+_233633348 3.099 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr2_+_233633279 3.093 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr4_-_105631915 3.073 NM_025212
CXXC4
CXXC finger protein 4
chr21_-_38792173 3.021 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr7_+_149779011 2.988 GIMAP8
GTPase, IMAP family member 8
chr5_-_169657360 2.977 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_176869148 2.973


chr17_+_44642587 2.945 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr16_-_3567354 2.920 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr5_+_168996852 2.809 DOCK2
dedicator of cytokinesis 2
chr8_+_11388918 2.801 NM_001715
BLK
B lymphoid tyrosine kinase
chr16_-_30301357 2.799 SEPT1
septin 1
chr15_+_79376295 2.787 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr19_+_14554895 2.746 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr17_+_7180571 2.743 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr9_-_129580732 2.738 NM_170600
SH2D3C
SH2 domain containing 3C
chr9_+_263025 2.721 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr1_+_9634368 2.720 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr6_-_56824371 2.716 DST
dystonin
chrX_-_70248022 2.710 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr17_+_31455332 2.705 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr1_-_154727014 2.683 MEF2D
myocyte enhancer factor 2D
chr12_+_25096472 2.677 NM_006152
LRMP
lymphoid-restricted membrane protein
chr1_+_154390939 2.639 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_-_122862447 2.633 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_207995999 2.620 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr17_-_24491521 2.609 MYO18A
myosin XVIIIA
chr12_-_120725210 2.602 LOC338799
hypothetical LOC338799
chr10_+_70517823 2.601 NM_002727
SRGN
serglycin
chr10_+_70517863 2.588 SRGN
serglycin
chr6_+_31662454 2.569 NM_205837
LST1
leukocyte specific transcript 1
chr19_+_54530512 2.568 CD37
CD37 molecule
chr3_-_122862391 2.562 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_+_54530485 2.559 NM_001040031
NM_001774
CD37

CD37 molecule

chr19_+_54530497 2.555 CD37
CD37 molecule
chr1_-_158759606 2.543 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr19_+_54530458 2.543 CD37
CD37 molecule
chr5_-_176869463 2.522 NM_024872
DOK3
docking protein 3
chr7_+_139175420 2.507 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chrX_-_44945025 2.484 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr11_+_5602782 2.477 NM_021616
TRIM34
tripartite motif containing 34
chr12_+_53177789 2.474 NCKAP1L
NCK-associated protein 1-like
chr18_-_59137948 2.465 BCL2
B-cell CLL/lymphoma 2
chr12_+_53177806 2.462 NCKAP1L
NCK-associated protein 1-like
chr11_-_60880799 2.462 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr5_-_176869440 2.448 DOK3
docking protein 3
chr19_+_54530546 2.417 CD37
CD37 molecule
chr16_-_30301634 2.388 NM_052838
SEPT1
septin 1
chr5_-_71838875 2.370 NM_152625
ZNF366
zinc finger protein 366
chr12_+_53177758 2.369 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr11_+_59979857 2.302 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr13_+_110653407 2.287 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_+_195889845 2.287 FAM43A
family with sequence similarity 43, member A
chr12_+_6930778 2.282 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6930815 2.281 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_25044156 2.273 FAM65B
family with sequence similarity 65, member B
chr6_+_31661934 2.264 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr12_+_6930799 2.260 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_+_120966280 2.253 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_159943385 2.247 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr4_-_10295412 2.233 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr12_+_6930804 2.228 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6930792 2.227 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_+_31647854 2.171 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr19_+_10242516 2.165 NM_000201
ICAM1
intercellular adhesion molecule 1
chr9_+_27099138 2.132 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr14_+_87541220 2.132 NM_003608
GPR65
G protein-coupled receptor 65
chr13_-_32678142 2.130 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr16_+_29581783 2.127 NM_001030288
SPN
sialophorin
chr5_+_75734759 2.113 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_+_6930734 2.111 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_+_65164167 2.107 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr6_-_33085290 2.077 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr7_+_150013716 2.064 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr11_-_60475558 2.053 NM_016582
SLC15A3
solute carrier family 15, member 3
chr16_+_29582065 2.046 SPN
sialophorin
chr7_-_37454933 2.044 NM_014800
ELMO1
engulfment and cell motility 1
chr6_-_33085329 2.043 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr1_-_181826086 2.024 NCF2
neutrophil cytosolic factor 2
chr1_+_165865953 2.023 NM_052862
RCSD1
RCSD domain containing 1
chr12_+_6930694 2.006 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr9_+_70509925 2.003 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr22_+_35586950 2.000 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr16_+_29582069 1.999 NM_003123
SPN
sialophorin
chr10_-_64246129 1.984 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr1_+_204797516 1.984 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr17_+_31664143 1.980 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr16_-_49272741 1.973 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr7_+_87401368 1.952 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr10_-_98470164 1.951 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr12_+_45896511 1.936 FAM113B
family with sequence similarity 113, member B
chr6_+_31651319 1.929 NM_000594
TNF
tumor necrosis factor
chr17_-_26672757 1.919 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr11_-_33847507 1.916 LMO2
LIM domain only 2 (rhombotin-like 1)
chr10_+_26767288 1.906 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_+_26767268 1.901 NM_019043
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_+_202000906 1.897 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr5_-_100266769 1.883 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr1_+_84540921 1.878 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr17_-_53764867 1.835


chr6_+_130381408 1.815 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr1_+_242281199 1.813 ZNF238
zinc finger protein 238
chr2_-_213723298 1.813 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_+_9713472 1.804 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr1_+_242281175 1.799 NM_205768
ZNF238
zinc finger protein 238
chr8_-_6407882 1.798 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr2_-_197883739 1.768 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr17_-_5078773 1.767 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr16_-_49272617 1.765 SNX20
sorting nexin 20
chr1_+_111818111 1.762 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr19_-_56567602 1.738 NM_005601
NKG7
natural killer cell group 7 sequence
chr6_+_336738 1.735 NM_001195286
NM_002460
IRF4

interferon regulatory factor 4

chr2_-_224974954 1.730 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr18_-_51219880 1.714 TCF4
transcription factor 4
chr12_+_55018925 1.688 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr12_+_91620749 1.681 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_-_181826633 1.671 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr1_-_181826292 1.666 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr17_+_69974361 1.663 CD300A
CD300a molecule
chr7_+_149895390 1.662 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr2_-_242449662 1.660 NM_005018
PDCD1
programmed cell death 1
chr9_+_126094067 1.656 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr9_-_37024358 1.647 NM_016734
PAX5
paired box 5
chr4_-_25473528 1.643 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_31003181 1.629 LAPTM5
lysosomal protein transmembrane 5
chr7_+_106293112 1.623 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_-_197883569 1.616 ANKRD44
ankyrin repeat domain 44
chr12_-_56159631 1.609 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr1_-_158883666 1.609 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr6_-_27949266 1.598 NM_003546
HIST1H4L
histone cluster 1, H4l
chr12_+_45896318 1.589 NM_138371
FAM113B
family with sequence similarity 113, member B
chr11_-_33847834 1.578 LMO2
LIM domain only 2 (rhombotin-like 1)
chr16_+_66236559 1.577 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr7_-_23476497 1.572 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr4_+_68107039 1.554 NM_012108
STAP1
signal transducing adaptor family member 1
chr10_-_53129315 1.553 NM_015235
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr5_-_124108672 1.551 NM_020747
ZNF608
zinc finger protein 608
chr2_+_68445821 1.541 NM_002664
PLEK
pleckstrin
chr1_-_31003260 1.537 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr9_+_92629525 1.532 NM_001174167
SYK
spleen tyrosine kinase
chr11_-_58736897 1.524 NM_001039396
MPEG1
macrophage expressed 1
chr22_-_35875890 1.522 NM_000878
IL2RB
interleukin 2 receptor, beta
chr6_+_31690957 1.511 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr9_+_126094388 1.510 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr3_+_120799411 1.510 NM_015900
PLA1A
phospholipase A1 member A
chr19_+_14412080 1.510 NM_213560
PKN1
protein kinase N1
chr7_+_68702516 1.510 AUTS2
autism susceptibility candidate 2
chr19_+_14412087 1.504 PKN1
protein kinase N1
chr17_+_27838821 1.494


chr7_+_73145481 1.488 LIMK1
LIM domain kinase 1
chr11_-_33847937 1.487 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 7.64e-13 GO:0002376 immune system process
1.43 3.40e-06 GO:0006955 immune response
1.26 2.04e-05 GO:0016070 RNA metabolic process
1.22 3.84e-05 GO:0090304 nucleic acid metabolic process
1.24 4.23e-05 GO:0010467 gene expression
1.69 8.21e-05 GO:0050865 regulation of cell activation
1.73 1.37e-04 GO:0051249 regulation of lymphocyte activation
1.40 1.46e-04 GO:0002682 regulation of immune system process
1.78 1.52e-04 GO:0050867 positive regulation of cell activation
1.10 1.52e-04 GO:0050794 regulation of cellular process
1.81 1.76e-04 GO:0051251 positive regulation of lymphocyte activation
1.68 2.12e-04 GO:0002694 regulation of leukocyte activation
1.06 3.04e-04 GO:0009987 cellular process
1.18 3.14e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79 3.16e-04 GO:0050863 regulation of T cell activation
1.76 3.76e-04 GO:0002696 positive regulation of leukocyte activation
1.09 4.37e-04 GO:0065007 biological regulation
1.32 4.43e-04 GO:0032774 RNA biosynthetic process
1.24 5.96e-04 GO:0034645 cellular macromolecule biosynthetic process
1.13 7.42e-04 GO:0044260 cellular macromolecule metabolic process
1.45 8.18e-04 GO:0001775 cell activation
1.23 1.02e-03 GO:0009059 macromolecule biosynthetic process
1.09 1.37e-03 GO:0050789 regulation of biological process
1.84 1.40e-03 GO:0050870 positive regulation of T cell activation
1.15 1.90e-03 GO:0007165 signal transduction
1.45 2.99e-03 GO:0002684 positive regulation of immune system process
1.61 3.14e-03 GO:0045321 leukocyte activation
1.68 3.82e-03 GO:0046649 lymphocyte activation
1.13 4.97e-03 GO:0023052 signaling
1.12 9.96e-03 GO:0051716 cellular response to stimulus
1.83 1.42e-02 GO:0042110 T cell activation
1.92 1.53e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.65 1.68e-02 GO:0002764 immune response-regulating signaling pathway
1.64 3.00e-02 GO:0002757 immune response-activating signal transduction
1.39 4.92e-02 GO:0050776 regulation of immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 4.57e-07 GO:0005654 nucleoplasm
1.25 8.96e-07 GO:0031981 nuclear lumen
1.13 9.10e-07 GO:0005634 nucleus
1.22 4.66e-06 GO:0044428 nuclear part
1.07 2.30e-05 GO:0043226 organelle
1.07 2.42e-05 GO:0043229 intracellular organelle
1.08 2.88e-05 GO:0043227 membrane-bounded organelle
1.08 3.44e-05 GO:0043231 intracellular membrane-bounded organelle
1.05 5.00e-05 GO:0044424 intracellular part
1.11 1.10e-04 GO:0044422 organelle part
1.19 1.22e-04 GO:0031974 membrane-enclosed lumen
1.11 1.31e-04 GO:0044446 intracellular organelle part
1.05 2.71e-04 GO:0005622 intracellular
1.18 2.87e-04 GO:0043233 organelle lumen
1.18 5.41e-04 GO:0070013 intracellular organelle lumen
1.18 1.56e-03 GO:0005829 cytosol
1.37 3.41e-03 GO:0030529 ribonucleoprotein complex
1.53 1.43e-02 GO:0016604 nuclear body
2.83 2.14e-02 GO:0070603 SWI/SNF-type complex
1.06 3.10e-02 GO:0005737 cytoplasm
1.02 4.36e-02 GO:0005623 cell
1.93 4.85e-02 GO:0030117 membrane coat
1.93 4.85e-02 GO:0048475 coated membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 5.57e-10 GO:0005515 protein binding
1.17 1.68e-05 GO:0003676 nucleic acid binding
1.05 1.18e-04 GO:0005488 binding
1.32 5.47e-04 GO:0003723 RNA binding
1.16 1.36e-02 GO:0003677 DNA binding
1.39 3.42e-02 GO:0003712 transcription cofactor activity
1.39 3.92e-02 GO:0000988 protein binding transcription factor activity
1.39 3.92e-02 GO:0000989 transcription factor binding transcription factor activity