Motif ID: SOX5.p2

Z-value: 1.231


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX5chr12_-_24606616-0.656.1e-03Click!


Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_105511615 7.047 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr11_-_16380967 6.393 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr3_-_150422474 2.906 NM_000096
CP
ceruloplasmin (ferroxidase)
chr9_-_129752687 2.275 NM_203305
FAM102A
family with sequence similarity 102, member A
chr12_+_68028397 2.215 NM_000239
LYZ
lysozyme
chr17_+_34114924 2.150 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_+_68028407 2.075 LYZ
lysozyme
chr14_-_22974707 2.059 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr3_+_152970904 1.872 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr3_+_173043832 1.861 NM_001164436
TMEM212
transmembrane protein 212
chr12_-_23995220 1.640 SOX5
SRY (sex determining region Y)-box 5
chr17_+_34115383 1.531 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr6_-_49712483 1.504 NM_000324
RHAG
Rh-associated glycoprotein
chr20_-_45418818 1.493 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr3_-_71376919 1.473 FOXP1
forkhead box P1
chr4_+_110968594 1.436 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr13_+_99431417 1.435


chr12_-_23995109 1.428 SOX5
SRY (sex determining region Y)-box 5
chr17_-_46479127 1.325 SPAG9
sperm associated antigen 9
chr17_-_53847937 1.281 RNF43
ring finger protein 43
chr3_-_121884091 1.251 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr11_+_22652957 1.231 GAS2
growth arrest-specific 2
chr3_+_186529376 1.229 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr2_-_174475528 1.219


chr4_+_74491272 1.216 ALB
albumin
chr3_-_121883647 1.215 HGD
homogentisate 1,2-dioxygenase
chr11_+_22652894 1.208 NM_005256
GAS2
growth arrest-specific 2
chr2_-_192420168 1.157 NM_004657
SDPR
serum deprivation response
chr2_+_228386800 1.136 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr6_-_24491498 1.123 NM_001195610
DCDC2
doublecortin domain containing 2
chr4_-_186969202 1.122 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr15_+_74416156 1.115 NM_145805
ISL2
ISL LIM homeobox 2
chr20_+_31613800 1.107 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr17_+_63252704 1.098 BPTF
bromodomain PHD finger transcription factor
chr10_-_31328426 1.075 NM_001143769
ZNF438
zinc finger protein 438
chr1_+_116727514 1.062 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr4_+_100714995 1.027 MTTP
microsomal triglyceride transfer protein
chr15_+_74416129 1.018 ISL2
ISL LIM homeobox 2
chr4_-_186969041 0.998 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr3_+_82117978 0.997


chr7_-_100077072 0.996 NM_003227
TFR2
transferrin receptor 2
chr2_+_143351536 0.991 NM_001032998
NM_003937
KYNU

kynureninase

chr2_-_21084077 0.985 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_+_62787534 0.942 NM_001142614
EHBP1
EH domain binding protein 1
chr2_+_169631777 0.915 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_148603769 0.914 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr15_-_32398220 0.909 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chrX_+_152562013 0.886 DUSP9
dual specificity phosphatase 9
chr11_+_73037382 0.883 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_27573206 0.881 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chrX_+_105823723 0.861 NM_024539
RNF128
ring finger protein 128
chr9_-_115880494 0.854 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr7_-_16471817 0.848 NM_015464
SOSTDC1
sclerostin domain containing 1
chr6_-_116488458 0.844 NM_002031
FRK
fyn-related kinase
chr12_-_101835183 0.843 PAH
phenylalanine hydroxylase
chrX_-_24600661 0.841 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr13_-_47885653 0.823 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr17_-_59817575 0.818 PECAM1
platelet/endothelial cell adhesion molecule
chr2_-_180135559 0.814 NM_001113398
ZNF385B
zinc finger protein 385B
chr6_-_135312899 0.814 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr18_-_28606839 0.809 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr16_-_45562840 0.794 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr12_-_101835510 0.792 NM_000277
PAH
phenylalanine hydroxylase
chr6_-_48186868 0.792 C6orf138
chromosome 6 open reading frame 138
chr17_-_59817456 0.790 PECAM1
platelet/endothelial cell adhesion molecule
chr5_-_125956996 0.789 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr5_-_148738980 0.784 NM_014443
IL17B
interleukin 17B
chr1_+_61319976 0.781 NM_001145512
NFIA
nuclear factor I/A
chr6_-_138862273 0.772


chr6_-_138862271 0.772 NM_001144060
NHSL1
NHS-like 1
chr16_-_30841938 0.766 NCRNA00095
non-protein coding RNA 95
chr6_-_138935359 0.752 NM_020464
NHSL1
NHS-like 1
chr2_-_238164042 0.749 RAB17
RAB17, member RAS oncogene family
chr17_+_63252668 0.749 BPTF
bromodomain PHD finger transcription factor
chr12_-_101835026 0.739 PAH
phenylalanine hydroxylase
chr10_+_24537725 0.737 NM_001098501
NM_019590
KIAA1217

KIAA1217

chrX_+_107569671 0.734 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr11_+_20005704 0.730 NAV2
neuron navigator 2
chr11_-_114880275 0.701 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr2_-_157890400 0.694 NM_020711
ERMN
ermin, ERM-like protein
chr7_-_96471544 0.685 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr2_+_203207912 0.685 FAM117B
family with sequence similarity 117, member B
chr14_-_19843969 0.683 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr7_+_116238309 0.683 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr13_-_40491491 0.681 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr14_+_38653177 0.678 NM_001009182
NM_001009183
NM_003616
SIP1


survival of motor neuron protein interacting protein 1


chr13_-_40491405 0.675 ELF1
E74-like factor 1 (ets domain transcription factor)
chr14_-_19843918 0.673 TTC5
tetratricopeptide repeat domain 5
chr10_-_101831579 0.667 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr1_+_148603613 0.667 NM_015203
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr4_-_176970895 0.657 GPM6A
glycoprotein M6A
chr18_+_53862386 0.654 NM_001144967
NM_015277
NEDD4L

neural precursor cell expressed, developmentally down-regulated 4-like

chr3_+_187917791 0.648 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr2_-_192419896 0.646 SDPR
serum deprivation response
chr1_-_12599934 0.643 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr17_-_59817722 0.640 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr16_-_66535923 0.639 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr4_-_159313167 0.638 NM_016613
FAM198B
family with sequence similarity 198, member B
chr8_-_82769761 0.637 NM_001010893
SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr12_-_110410730 0.632 ATXN2
ataxin 2
chr20_+_10363949 0.631 NM_001009608
C20orf94
chromosome 20 open reading frame 94
chr1_+_196874867 0.628 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_+_111313067 0.624 NM_001037954
DIXDC1
DIX domain containing 1
chr10_+_101532450 0.620 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr16_-_66535457 0.617 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr9_+_676640 0.612


chrX_+_70419766 0.604 NM_001145408
NM_001145409
NM_001145410
NM_007363
NONO



non-POU domain containing, octamer-binding



chr20_+_254205 0.603 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr13_+_96726197 0.597 MBNL2
muscleblind-like 2 (Drosophila)
chr4_-_176971175 0.592 NM_201591
GPM6A
glycoprotein M6A
chr17_-_59817654 0.589 PECAM1
platelet/endothelial cell adhesion molecule
chr11_+_22644732 0.586 NM_001143830
GAS2
growth arrest-specific 2
chr6_+_148705421 0.585 NM_015278
SASH1
SAM and SH3 domain containing 1
chr6_+_43135346 0.583 NM_138343
NM_201521
KLC4

kinesin light chain 4

chr21_+_17807167 0.578 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr5_+_147754467 0.576 FBXO38
F-box protein 38
chr20_+_23293020 0.575 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr11_+_111313227 0.575 DIXDC1
DIX domain containing 1
chrX_+_152684150 0.574 PLXNB3
plexin B3
chr13_+_96726415 0.570 MBNL2
muscleblind-like 2 (Drosophila)
chr16_+_1068781 0.564 NM_001053
SSTR5
somatostatin receptor 5
chr6_+_64414389 0.559 NM_015153
PHF3
PHD finger protein 3
chr2_-_225073357 0.559 CUL3
cullin 3
chr9_+_114289178 0.558 KIAA1958
KIAA1958
chr14_+_38772870 0.555 NM_054024
MIA2
melanoma inhibitory activity 2
chr17_-_59818033 0.554 PECAM1
platelet/endothelial cell adhesion molecule
chr7_+_128802719 0.549 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr6_+_29902734 0.541 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr3_+_52803823 0.539 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr4_-_40211324 0.537 RBM47
RNA binding motif protein 47
chr20_+_5935897 0.537 NM_001127458
CRLS1
cardiolipin synthase 1
chr8_-_38324809 0.535 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr2_+_166137091 0.535 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr2_+_203208064 0.535 NM_173511
FAM117B
family with sequence similarity 117, member B
chr9_+_115265827 0.534 NM_017790
RGS3
regulator of G-protein signaling 3
chr1_+_29113589 0.531 NM_001166006
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr19_+_7566698 0.528 NM_001080429
NM_020902
KIAA1543

KIAA1543

chr3_+_120983556 0.528 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr4_-_159312973 0.525 FAM198B
family with sequence similarity 198, member B
chr6_-_143813481 0.524 NM_182503
ADAT2
adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae)
chr1_-_108032645 0.524 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr10_+_114699953 0.521 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr1_+_148603208 0.512 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr14_-_19871267 0.512 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr16_-_11282595 0.505 NM_002761
PRM1
protamine 1
chr1_+_196874839 0.503 PTPRC
protein tyrosine phosphatase, receptor type, C
chr14_+_34583863 0.502 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr19_+_60580015 0.500 NM_139172
TMEM190
transmembrane protein 190
chr14_+_22860547 0.498 PABPN1
poly(A) binding protein, nuclear 1
chr2_+_201755865 0.496 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr10_+_101532544 0.496 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr9_+_134884627 0.495 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr4_+_71418886 0.494 NM_212557
AMTN
amelotin
chr19_-_17236522 0.491 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chrX_-_107569256 0.491 NM_001847
COL4A6
collagen, type IV, alpha 6
chr11_+_46358909 0.490 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr2_+_138438277 0.490 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr3_+_162697289 0.490 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr6_+_148705817 0.490 SASH1
SAM and SH3 domain containing 1
chr6_-_43135092 0.488 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr3_+_120983620 0.486 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr7_-_111633428 0.486 DOCK4
dedicator of cytokinesis 4
chr4_+_39084867 0.485 NM_175737
KLB
klotho beta
chr17_-_1359745 0.484 INPP5K
inositol polyphosphate-5-phosphatase K
chr2_-_39310176 0.483 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr1_-_229627412 0.479 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr7_-_150737980 0.478 NM_198285
WDR86
WD repeat domain 86
chr4_-_105635499 0.474 CXXC4
CXXC finger protein 4
chr4_+_124537334 0.471 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_-_160181206 0.470 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_+_559129 0.469


chr7_-_111633620 0.469 NM_014705
DOCK4
dedicator of cytokinesis 4
chr6_-_116973465 0.469 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr12_-_85756766 0.469 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr22_-_35428848 0.468 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr6_+_43135606 0.465 NM_201523
KLC4
kinesin light chain 4
chr7_+_111633972 0.465 ZNF277
zinc finger protein 277
chr2_-_21087435 0.461 APOB
apolipoprotein B (including Ag(x) antigen)
chr12_-_120725210 0.460 LOC338799
hypothetical LOC338799
chr9_+_138810610 0.460 NM_001039374
KIAA1984
KIAA1984
chr4_+_90252990 0.460 NM_145715
TIGD2
tigger transposable element derived 2
chr3_+_182900081 0.457 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr3_-_57505107 0.456 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr19_+_12810258 0.454 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr3_+_46591048 0.454 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr1_+_45926433 0.453 NM_016486
TMEM69
transmembrane protein 69
chr4_+_109763119 0.449 RPL34
ribosomal protein L34
chr7_+_156128431 0.446 NM_001184997
RNF32
ring finger protein 32
chr17_-_44058612 0.446 NM_024017
HOXB9
homeobox B9
chr12_+_56114724 0.445 NM_005538
INHBC
inhibin, beta C
chr7_+_111633878 0.444 NM_021994
ZNF277
zinc finger protein 277
chr1_-_198643885 0.441 ZNF281
zinc finger protein 281
chr17_+_56032271 0.439 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr1_-_57057956 0.434 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr11_+_129496792 0.432 APLP2
amyloid beta (A4) precursor-like protein 2
chr12_+_14429499 0.431 ATF7IP
activating transcription factor 7 interacting protein
chr19_-_4491024 0.427 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr2_+_120233676 0.424 NM_002830
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr2_-_215953818 0.421 FN1
fibronectin 1
chr7_-_156495314 0.420 MNX1
motor neuron and pancreas homeobox 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.