• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: NANOG.p2

Z-value: 1.063

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_+_51025604	3.548	NM_001042481	FRMD6	FERM domain containing 6
chr2_+_17861266	3.238	NM_001105569	MSGN1	mesogenin 1
chr13_-_40491491	1.644	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr13_-_40491405	1.618		ELF1	E74-like factor 1 (ets domain transcription factor)
chr10_-_105835525	1.614		COL17A1	collagen, type XVII, alpha 1
chr6_+_34314545	1.564	NM_145905	HMGA1	high mobility group AT-hook 1
chr10_-_105835609	1.461	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr12_-_15005761	1.360	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr10_-_13789628	1.284		FRMD4A	FERM domain containing 4A
chr14_+_77939845	1.217	NM_004796	NRXN3	neurexin 3
chr7_+_128802719	1.213	NM_001130722	AHCYL2	adenosylhomocysteinase-like 2
chr18_+_19826734	1.213	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr22_-_39189369	1.198		MKL1	megakaryoblastic leukemia (translocation) 1
chr12_-_51114372	1.141	NM_004693	KRT75	keratin 75
chr2_+_170742900	1.131	NM_001083615 NM_001171642 NM_138995	MYO3B	myosin IIIB
chr2_+_157822355	1.112	NM_014568	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chrX_+_134482212	1.092	NM_182540	DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr15_+_38849450	1.077	NM_001130448	C15orf62	chromosome 15 open reading frame 62
chr3_+_123279439	1.065	NM_006889	CD86	CD86 molecule
chr3_+_161040439	1.048		SCHIP1	schwannomin interacting protein 1
chr10_+_11246934	1.044	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr17_-_53849888	1.034		RNF43	ring finger protein 43
chr1_+_165565006	1.027		POU2F1	POU class 2 homeobox 1
chr3_+_161040343	1.020	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr11_-_58736897	0.981	NM_001039396	MPEG1	macrophage expressed 1
chr7_+_50318801	0.956		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr1_+_165564904	0.940	NM_001198783	POU2F1	POU class 2 homeobox 1
chr6_-_32605898	0.935	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr8_-_10550026	0.914	NM_178857	RP1L1	retinitis pigmentosa 1-like 1
chr12_+_25096472	0.892	NM_006152	LRMP	lymphoid-restricted membrane protein
chr12_-_51200347	0.866	NM_000424	KRT5	keratin 5
chr11_-_110755112	0.856		POU2AF1	POU class 2 associating factor 1
chr12_+_25096755	0.833		LRMP	lymphoid-restricted membrane protein
chr1_+_196874839	0.825		PTPRC	protein tyrosine phosphatase, receptor type, C
chr11_-_56951628	0.822	NM_017611	SLC43A3	solute carrier family 43, member 3
chr7_-_25234582	0.816	NM_022150	NPVF	neuropeptide VF precursor
chr1_+_196874759	0.811	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr2_+_108604111	0.809	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr1_+_180836050	0.806
chr11_-_118405288	0.803	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr17_-_53849929	0.795	NM_017763	RNF43	ring finger protein 43
chr6_-_32665409	0.791	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr13_-_93929719	0.789	NM_001129889 NM_001922	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
chr7_+_113853790	0.787	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr11_-_83071084	0.782	NM_001142702	DLG2	discs, large homolog 2 (Drosophila)
chrX_+_134482387	0.778		DDX26B	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr3_-_57209319	0.708	NM_003865	HESX1	HESX homeobox 1
chr3_-_145049853	0.705	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr17_-_78391178	0.703	NM_024702	ZNF750	zinc finger protein 750
chr10_+_82290554	0.701	NM_001145719	SH2D4B	SH2 domain containing 4B
chr18_+_27281729	0.691	NM_001944	DSG3	desmoglein 3
chr17_-_36165050	0.689	NM_181534	KRT25	keratin 25
chr16_-_21221872	0.685	NM_001014444 NM_001888	CRYM	crystallin, mu
chr13_-_83354474	0.651	NM_052910	SLITRK1	SLIT and NTRK-like family, member 1
chr13_-_83354425	0.631		SLITRK1	SLIT and NTRK-like family, member 1
chr11_+_58146721	0.630	NM_000614	CNTF	ciliary neurotrophic factor
chr6_+_34312906	0.619		HMGA1	high mobility group AT-hook 1
chr18_+_54039730	0.618	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr3_+_154362726	0.615		RAP2B	RAP2B, member of RAS oncogene family
chr4_+_77575276	0.609	NM_020859	SHROOM3	shroom family member 3
chr6_-_26343139	0.589	NM_005320	HIST1H1D	histone cluster 1, H1d
chr13_-_98708549	0.584	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr1_-_42157077	0.582	NM_001127714 NM_024503	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr11_-_123353607	0.577	NM_001004474	OR10S1	olfactory receptor, family 10, subfamily S, member 1
chr1_-_42156957	0.568		HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr18_+_54039818	0.567		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr13_+_23042722	0.566	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr3_-_152517204	0.563	NM_023915	GPR87	G protein-coupled receptor 87
chr3_+_113200696	0.562	NM_001008273	TAGLN3	transgelin 3
chrX_+_55951280	0.558
chr9_-_5294579	0.547	NM_005059 NM_134441	RLN2	relaxin 2
chr18_+_54039779	0.541		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_169713458	0.529	NM_001034838	KCNIP1	Kv channel interacting protein 1
chr2_-_98646367	0.526	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr6_+_32713160	0.525	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr6_+_44076281	0.524	NM_001171992 NM_153246	C6orf223	chromosome 6 open reading frame 223
chr2_-_55090759	0.513	NM_007008	RTN4	reticulon 4
chr3_+_190990142	0.507	NM_001114980 NM_001114981 NM_001114982	TP63	tumor protein p63
chr12_+_45896511	0.503		FAM113B	family with sequence similarity 113, member B
chr1_-_42156913	0.502
chr3_-_110155237	0.499	NM_005459	GUCA1C	guanylate cyclase activator 1C
chr18_+_55718171	0.492	NM_021127	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1
chr13_+_108079570	0.480	NM_001198950	MYO16	myosin XVI
chr5_-_56814310	0.477	NM_001017992	ACTBL2	actin, beta-like 2
chr14_+_75907442	0.475	NM_004452	ESRRB	estrogen-related receptor beta
chr14_-_56342097	0.472	NM_172337	OTX2	orthodenticle homeobox 2
chr3_-_120861959	0.470	NM_022135	POPDC2	popeye domain containing 2
chr7_-_13992351	0.460	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr19_+_40632456	0.459	NM_005306	FFAR2	free fatty acid receptor 2
chr17_-_39094787	0.458	NM_001040002	MEOX1	mesenchyme homeobox 1
chr6_-_112033752	0.452		TRAF3IP2	TRAF3 interacting protein 2
chr10_-_123346148	0.450	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr18_-_26996742	0.444	NM_004948 NM_024421	DSC1	desmocollin 1
chr11_+_59979857	0.444	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr3_+_113200275	0.443	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr4_-_40631397	0.437		APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_+_158636987	0.431	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr1_-_230717850	0.428	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr1_-_108032645	0.423	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr18_+_13601664	0.421	NM_001003674 NM_001003675	C18orf1	chromosome 18 open reading frame 1
chr12_+_47205681	0.418	NM_001005203	OR8S1	olfactory receptor, family 8, subfamily S, member 1
chr9_+_129066576	0.414	NM_032293	GARNL3	GTPase activating Rap/RanGAP domain-like 3
chr1_-_149004852	0.407		CTSS	cathepsin S
chr6_-_32742265	0.402	NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr3_+_138132006	0.401	NM_001190796	NCK1	NCK adaptor protein 1
chr17_-_74244539	0.398
chr4_-_83566246	0.398		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr6_-_42798286	0.397	NM_000322	PRPH2	peripherin 2 (retinal degeneration, slow)
chr6_-_116973465	0.395	NM_001139444	BET3L	BET3 like (S. cerevisiae)
chr7_+_63411813	0.394		ZNF736	zinc finger protein 736
chr4_+_110968594	0.383	NM_006583	RRH	retinal pigment epithelium-derived rhodopsin homolog
chr8_+_32905027	0.376
chr4_+_169250281	0.370	NM_007193	ANXA10	annexin A10
chr8_-_102029997	0.369		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_+_113542017	0.367	NM_173161	IL1F10	interleukin 1 family, member 10 (theta)
chrX_-_116991728	0.366	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chr5_-_168204430	0.365
chr7_+_116447527	0.363		ST7	suppression of tumorigenicity 7
chr11_-_119514058	0.358	NM_012101	TRIM29	tripartite motif containing 29
chr1_+_42920635	0.356	NM_004559	YBX1	Y box binding protein 1
chr13_+_47948586	0.355		RB1	retinoblastoma 1
chr19_+_7874701	0.355		MAP2K7	mitogen-activated protein kinase kinase 7
chr6_-_112033775	0.355		TRAF3IP2	TRAF3 interacting protein 2
chr6_+_88026338	0.352		ZNF292	zinc finger protein 292
chr12_+_8167494	0.349	NM_016184 NM_194447 NM_194448 NM_194450	CLEC4A	C-type lectin domain family 4, member A
chr19_-_56147971	0.342	NM_001077491 NM_001077492 NM_012427	KLK5	kallikrein-related peptidase 5
chr10_+_47216925	0.342	NM_001630	ANXA8L2 ANXA8	annexin A8-like 2 annexin A8
chr1_+_50342168	0.340	NM_001144776	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_149004916	0.338	NM_004079	CTSS	cathepsin S
chr3_+_2528272	0.337		CNTN4	contactin 4
chr18_+_18989786	0.337	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr6_+_34312979	0.335		HMGA1	high mobility group AT-hook 1
chr7_-_107930170	0.332		PNPLA8	patatin-like phospholipase domain containing 8
chr5_-_169657395	0.330	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_+_135544214	0.330		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chrX_-_10761729	0.330	NM_033290	MID1	midline 1 (Opitz/BBB syndrome)
chr8_+_26206648	0.329	NM_001177591	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr22_+_38652555	0.329		GRAP2	GRB2-related adaptor protein 2
chr17_-_9635325	0.327	NM_001105571	DHRS7C	dehydrogenase/reductase (SDR family) member 7C
chr20_+_58004811	0.321	NM_021810	CDH26	cadherin 26
chr15_-_75259714	0.320		PEAK1	NKF3 kinase family member
chr3_+_157877146	0.319	NM_001184718	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr19_-_51829778	0.319	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr2_-_166638376	0.316	NM_001165963 NM_001165964 NM_006920	SCN1A	sodium channel, voltage-gated, type I, alpha subunit
chr11_+_7574992	0.314		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_123695302	0.313	NM_001002918	OR8D2	olfactory receptor, family 8, subfamily D, member 2
chr14_+_69307914	0.312		SRSF5	serine/arginine-rich splicing factor 5
chr17_-_38529638	0.308	NM_007298	BRCA1	breast cancer 1, early onset
chr11_+_10433241	0.308	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr11_+_65164167	0.306	NM_153253	SIPA1	signal-induced proliferation-associated 1
chr21_-_30460841	0.302	NM_012131	CLDN17	claudin 17
chr13_+_110637173	0.300	NM_001113513	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr11_+_123986661	0.300	NM_052959	PANX3	pannexin 3
chr17_-_9870292	0.298	NM_001130831	GAS7	growth arrest-specific 7
chr6_+_34312633	0.297		HMGA1	high mobility group AT-hook 1
chr12_+_45896318	0.297	NM_138371	FAM113B	family with sequence similarity 113, member B
chr22_+_44828338	0.297
chr11_-_16380967	0.296	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr7_-_129379947	0.296	NM_003344 NM_182697	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
chr7_+_129693938	0.296	NM_001869	CPA2	carboxypeptidase A2 (pancreatic)
chr12_-_51065629	0.295	NM_033045	KRT84	keratin 84
chr15_-_74091817	0.294	NM_138573	NRG4	neuregulin 4
chrX_-_19727828	0.292	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr3_+_89239494	0.291		EPHA3	EPH receptor A3
chr1_+_50347188	0.290		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_+_50348052	0.290		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_+_24354387	0.289	NM_003817	ADAM7	ADAM metallopeptidase domain 7
chr6_-_112034166	0.286	NM_001164281 NM_147686	TRAF3IP2	TRAF3 interacting protein 2
chr3_-_122862391	0.284		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr10_-_21475493	0.278	NM_001010896 NM_001177483	C10orf113	chromosome 10 open reading frame 113
chr1_-_6341553	0.278	NM_181866	ACOT7	acyl-CoA thioesterase 7
chr1_-_150328153	0.276	NM_001008536	TCHHL1	trichohyalin-like 1
chr10_+_49279647	0.276	NM_002750 NM_139046 NM_139047 NM_139049	MAPK8	mitogen-activated protein kinase 8
chr12_-_55614311	0.276	NM_148897	SDR9C7	short chain dehydrogenase/reductase family 9C, member 7
chr12_+_14429499	0.275		ATF7IP	activating transcription factor 7 interacting protein
chr11_+_20005704	0.275		NAV2	neuron navigator 2
chr12_-_14740694	0.275	NM_004963	GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)
chr2_+_161980865	0.275	NM_006593	TBR1	T-box, brain, 1
chrX_-_133620103	0.273	NM_021796	PLAC1	placenta-specific 1
chr17_+_22823151	0.272	NM_014238	KSR1	kinase suppressor of ras 1
chr3_+_154362714	0.270	NM_002886	RAP2B	RAP2B, member of RAS oncogene family
chr1_+_196874867	0.269		PTPRC	protein tyrosine phosphatase, receptor type, C
chrX_+_110252960	0.269	NM_001128168 NM_001128172 NM_001128173	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr16_+_55373241	0.266		NUP93	nucleoporin 93kDa
chrX_+_41191630	0.265	NM_022567	NYX	nyctalopin
chr9_-_85773899	0.261		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr12_-_107551783	0.261	NM_003006	SELPLG	selectin P ligand
chr7_+_18501876	0.260	NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr6_+_34312641	0.259		HMGA1	high mobility group AT-hook 1
chr3_-_122862447	0.257	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr5_+_115415061	0.254	NM_001195581	LOC644100	hypothetical LOC644100
chr7_-_36992221	0.254	NM_130442	ELMO1	engulfment and cell motility 1
chr9_-_14076901	0.253		NFIB	nuclear factor I/B
chr9_+_12683385	0.251	NM_000550	TYRP1	tyrosinase-related protein 1
chr5_+_125786975	0.251		GRAMD3	GRAM domain containing 3
chr7_-_104696678	0.250	NM_182691	SRPK2	SRSF protein kinase 2
chr15_-_53349775	0.250	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr10_+_11247243	0.246		CELF2	CUGBP, Elav-like family member 2
chr11_+_117762432	0.244		UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr18_+_59726183	0.244		SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.35	2.36e-05	GO:0032501	multicellular organismal process
2.08	3.94e-05	GO:0007600	sensory perception
1.70	4.33e-05	GO:0003008	system process
1.73	5.60e-04	GO:0050877	neurological system process
1.35	4.84e-02	GO:0048856	anatomical structure development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
10.55	2.94e-03	GO:0042613	MHC class II protein complex
2.80	1.47e-02	GO:0005882	intermediate filament
3.69	2.59e-02	GO:0045095	keratin filament
2.55	3.51e-02	GO:0045111	intermediate filament cytoskeleton
1.26	4.86e-02	GO:0005886	plasma membrane
12.30	4.88e-02	GO:0033162	melanosome membrane
12.30	4.88e-02	GO:0045009	chitosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.88	8.42e-04	GO:0004930	G-protein coupled receptor activity
1.52	6.67e-03	GO:0004872	receptor activity
1.59	1.39e-02	GO:0004888	transmembrane receptor activity