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Motif ID: REST.p3

Z-value: 0.993

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_99599984	1.646	NM_001010917	GOLGA7B	golgin A7 family, member B
chr20_+_30019465	1.272	NM_001011718	XKR7	XK, Kell blood group complex subunit-related family, member 7
chr11_-_72170533	1.266		STARD10	StAR-related lipid transfer (START) domain containing 10
chr8_-_145530639	1.243	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr12_+_46133	1.200	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr3_-_48675321	1.064	NM_001407	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr19_+_45728270	1.021		SPTBN4	spectrin, beta, non-erythrocytic 4
chr19_+_45728207	1.014	NM_025213	SPTBN4	spectrin, beta, non-erythrocytic 4
chr1_-_207892420	0.980	NM_000228	LAMB3	laminin, beta 3
chr10_+_60607232	0.937	NM_001143774	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_+_116131889	0.780	NM_000608	ORM2	orosomucoid 2
chr11_-_125278296	0.712	NM_031307	PUS3	pseudouridylate synthase 3
chr7_+_145444385	0.704	NM_014141	CNTNAP2	contactin associated protein-like 2
chrX_-_48943582	0.682	NM_003179	SYP	synaptophysin
chr12_-_3472245	0.612		LOC100129223	hypothetical LOC100129223
chr20_-_61755145	0.585	NM_015894	STMN3	stathmin-like 3
chr11_-_65871592	0.572	NM_006876	B3GNT1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr14_-_73962557	0.555	NM_001105579	TMEM90A	transmembrane protein 90A
chr19_-_60383280	0.554	NM_003180	SYT5	synaptotagmin V
chr6_+_43711532	0.544	NM_014628	MAD2L1BP	MAD2L1 binding protein
chr6_+_43711566	0.530		MAD2L1BP	MAD2L1 binding protein
chr10_+_26545241	0.520	NM_000818 NM_001134366	GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr5_-_151284515	0.484	NM_000171 NM_001146040	GLRA1	glycine receptor, alpha 1
chr20_-_60228665	0.482	NM_007232	HRH3	histamine receptor H3
chr7_-_100595552	0.472	NM_003378	VGF	VGF nerve growth factor inducible
chr12_+_117903682	0.462	NM_194286	SRRM4	serine/arginine repetitive matrix 4
chr19_-_50619015	0.461	NM_001166049 NM_001983	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr6_+_25760352	0.450	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr14_-_93829347	0.436	NM_001100607	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr15_-_81175542	0.416	NM_004644	AP3B2	adaptor-related protein complex 3, beta 2 subunit
chr16_+_4948318	0.406	NM_014692	SEC14L5	SEC14-like 5 (S. cerevisiae)
chr5_-_175969697	0.401	NM_052899	GPRIN1	G protein regulated inducer of neurite outgrowth 1
chr11_+_64565118	0.394		SAC3D1	SAC3 domain containing 1
chr19_-_50618982	0.393		ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr1_-_102235377	0.380	NM_058170	OLFM3	olfactomedin 3
chr3_+_195336625	0.378	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr17_-_24357014	0.366	NM_001098635 NM_178860	SEZ6	seizure related 6 homolog (mouse)
chr12_-_97812633	0.359		ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B
chr4_-_175986952	0.357	NM_001042543 NM_006529	GLRA3	glycine receptor, alpha 3
chr15_+_92575767	0.357		MCTP2	multiple C2 domains, transmembrane 2
chrX_-_152794478	0.341		L1CAM	L1 cell adhesion molecule
chr19_-_50618921	0.335		ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chrX_-_47364173	0.322	NM_006950 NM_133499	SYN1	synapsin I
chr2_-_51112743	0.314		NRXN1	neurexin 1
chr3_-_133236447	0.311	NM_130808	CPNE4	copine IV
chr1_-_102234959	0.306		OLFM3	olfactomedin 3
chr3_+_122109716	0.303	NM_014980	STXBP5L	syntaxin binding protein 5-like
chr6_+_158877640	0.290		TMEM181	transmembrane protein 181
chr1_+_208178198	0.284		SYT14	synaptotagmin XIV
chr12_-_29828958	0.284	NM_175861	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr1_-_149955870	0.275	NM_007185	CELF3	CUGBP, Elav-like family member 3
chr3_+_195336631	0.265		HES1	hairy and enhancer of split 1, (Drosophila)
chr19_-_45416043	0.259		TTC9B	tetratricopeptide repeat domain 9B
chr17_+_70178850	0.252	NM_175738	RAB37	RAB37, member RAS oncogene family
chr20_+_44091219	0.248	NM_020708	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr5_+_175231210	0.244		CPLX2	complexin 2
chr10_+_69990050	0.243	NM_030625	TET1	tet oncogene 1
chr8_-_145723209	0.242	NM_001024678	LRRC24	leucine rich repeat containing 24
chr10_-_50640327	0.241	NM_001143996 NM_001143997 NM_018245	OGDHL	oxoglutarate dehydrogenase-like
chr5_+_175231170	0.240
chr6_+_44346457	0.236	NM_001137560	TMEM151B	transmembrane protein 151B
chr6_+_158877455	0.234	NM_020823	TMEM181	transmembrane protein 181
chr17_+_70178911	0.231		RAB37	RAB37, member RAS oncogene family
chr19_-_45416112	0.226	NM_152479	TTC9B	tetratricopeptide repeat domain 9B
chr20_+_5839973	0.225	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr8_-_91164100	0.224	NM_004929	CALB1	calbindin 1, 28kDa
chr19_-_50618599	0.220		ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr17_-_3283884	0.215	NM_003554	OR1E2	olfactory receptor, family 1, subfamily E, member 2
chr20_+_44091265	0.213		SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr19_+_38867273	0.212	NM_022467	CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr15_-_29950188	0.212		OTUD7A	OTU domain containing 7A
chr5_+_175231098	0.211	NM_001008220	CPLX2	complexin 2
chr19_-_50618659	0.205	NM_202001	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr5_-_135729062	0.195	NM_001167576 NM_001167577 NM_020389	TRPC7	transient receptor potential cation channel, subfamily C, member 7
chrX_-_47364039	0.178
chr15_-_29950070	0.174		OTUD7A	OTU domain containing 7A
chr1_+_33124658	0.173	NM_002143	HPCA	hippocalcin
chr16_+_24174975	0.169		CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr18_-_5187240	0.161	NM_001145194	LOC642597	hypothetical protein LOC642597
chr17_-_7095622	0.160	NM_001143775	CTDNEP1	CTD nuclear envelope phosphatase 1
chr14_+_92459197	0.159	NM_001275	CHGA	chromogranin A (parathyroid secretory protein 1)
chr19_-_44427446	0.155	NM_172139	IL28B	interleukin 28B (interferon, lambda 3)
chr17_+_39741306	0.155	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr2_+_131230252	0.154	NM_001105194 NM_001105195	FAM123C	family with sequence similarity 123C
chr9_-_138236775	0.154	NM_178138	LHX3	LIM homeobox 3
chr8_-_94046891	0.140	NM_001191036	C8orf83	chromosome 8 open reading frame 83
chr14_+_92459244	0.140		CHGA	chromogranin A (parathyroid secretory protein 1)
chr1_+_170017452	0.139		METTL13	methyltransferase like 13
chr4_+_158361185	0.137	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr12_+_112280753	0.136	NM_001159727 NM_173542	PLBD2	phospholipase B domain containing 2
chr1_-_33108876	0.132	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr1_+_208178160	0.130	NM_001146261 NM_001146262 NM_001146264 NM_153262	SYT14	synaptotagmin XIV
chr14_+_20226762	0.129	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chrX_-_152794592	0.125	NM_000425 NM_001143963 NM_024003	L1CAM	L1 cell adhesion molecule
chr1_+_1836125	0.121	NM_138705	CALML6	calmodulin-like 6
chr5_+_175231144	0.113		CPLX2	complexin 2
chr9_-_103397023	0.109	NM_147180	PPP3R2	protein phosphatase 3, regulatory subunit B, beta
chr16_+_66244314	0.109		RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr1_+_210672817	0.108	NM_013349	NENF	neuron derived neurotrophic factor
chr6_+_138767007	0.106	NM_014320	HEBP2	heme binding protein 2
chr10_+_26545599	0.104		GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr10_+_73225533	0.103	NM_001171933 NM_001171934	CDH23	cadherin-related 23
chr6_+_138767151	0.103		HEBP2	heme binding protein 2
chr11_+_62136788	0.102	NM_000327	ROM1	retinal outer segment membrane protein 1
chr12_+_112280757	0.102		PLBD2	phospholipase B domain containing 2
chr6_-_32121784	0.099	NM_032470	TNXB	tenascin XB
chr1_+_152806924	0.099		CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr6_+_35881048	0.096	NM_182548	LHFPL5	lipoma HMGIC fusion partner-like 5
chr16_+_2959342	0.091	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr17_-_3248453	0.088	NM_003553	OR1E1	olfactory receptor, family 1, subfamily E, member 1
chr22_+_18388656	0.086		C22orf25	chromosome 22 open reading frame 25
chr1_+_170017430	0.083		METTL13	methyltransferase like 13
chr22_+_18388633	0.079		C22orf25	chromosome 22 open reading frame 25
chr8_-_94047440	0.075	NM_001191035 NM_001171795 NM_001171796 NM_001171797 NM_001171798 NM_001171799	C8orf83	chromosome 8 open reading frame 83
chr16_+_2959362	0.075		PAQR4	progestin and adipoQ receptor family member IV
chr1_-_173979292	0.074	NM_003285	TNR	tenascin R (restrictin, janusin)
chr6_+_43257903	0.073		CUL9	cullin 9
chr1_+_170017383	0.072	NM_001007239 NM_014955 NM_015935	METTL13	methyltransferase like 13
chr2_-_219791638	0.070		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr16_+_24175173	0.070		CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr7_+_8439762	0.070		NXPH1	neurexophilin 1
chr19_-_50429306	0.068	NM_138568	EXOC3L2	exocyst complex component 3-like 2
chr2_-_219791902	0.067	NM_005689	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_+_207215386	0.064	NM_001102659	LOC200726	hCG1657980
chr11_-_122357545	0.064	NM_001098169	BSX	brain-specific homeobox
chr22_+_18388602	0.063	NM_152906	C22orf25	chromosome 22 open reading frame 25
chr7_+_154943466	0.051	NM_001427	EN2	engrailed homeobox 2
chr7_+_8440109	0.040	NM_152745	NXPH1	neurexophilin 1
chr9_+_139153409	0.039	NM_000832 NM_001185090 NM_001185091 NM_007327 NM_021569	GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr6_+_43257883	0.038	NM_015089	CUL9	cullin 9
chr8_+_11703368	0.037		FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr3_+_9720509	0.037	NM_153635	CPNE9	copine family member IX
chr1_-_239749634	0.036		FH	fumarate hydratase
chrX_+_152891184	0.035	NM_003492	TMEM187	transmembrane protein 187
chr17_+_77925441	0.034	NM_018949	UTS2R	urotensin 2 receptor
chr16_+_2450081	0.033	NM_025108	C16orf59	chromosome 16 open reading frame 59
chr12_+_111713931	0.032	NM_001143854 NM_014954	RPH3A	rabphilin 3A homolog (mouse)
chr10_+_28862514	0.032		WAC	WW domain containing adaptor with coiled-coil
chr17_-_37022465	0.031	NM_005557	KRT16	keratin 16
chr5_-_70621688	0.030		SMA4	glucuronidase, beta pseudogene
chr9_-_130078017	0.030	NM_004486	GOLGA2	golgin A2
chr18_-_53404783	0.030	NM_000140 NM_001012515	FECH	ferrochelatase
chr8_+_80685859	0.027		STMN2	stathmin-like 2
chr6_+_154402135	0.024	NM_000914 NM_001008503 NM_001008504 NM_001008505 NM_001145282 NM_001145283 NM_001145285 NM_001145286 NM_001145284	OPRM1	opioid receptor, mu 1
chr8_-_57521065	0.023	NM_006211	PENK	proenkephalin
chr17_-_62793097	0.021		PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr17_-_62793129	0.019	NM_002816 NM_174871	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr17_+_27838041	0.016	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_11500912	0.016	NM_001142464 NM_001142465 NM_016581	ECSIT	ECSIT homolog (Drosophila)
chr20_+_56861430	0.016	NM_001077490 NM_080425	GNAS	GNAS complex locus
chr2_-_51113040	0.015	NM_001135659 NM_004801	NRXN1	neurexin 1
chr1_-_239749683	0.015	NM_000143	FH	fumarate hydratase
chr3_-_188870799	0.013	NM_001048	SST	somatostatin
chr21_-_34749908	0.012	NM_001127670	KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr15_+_73074882	0.012	NM_001178111 NM_001178112 NM_138967	SCAMP5	secretory carrier membrane protein 5
chr3_-_25680723	0.011	NM_001068	TOP2B	topoisomerase (DNA) II beta 180kDa
chr15_-_24570010	0.010	NM_021912	GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr17_-_77474597	0.010	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr5_-_69917721	0.008		SMA4	glucuronidase, beta pseudogene
chr1_-_20707103	0.000		MUL1	mitochondrial E3 ubiquitin protein ligase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
6.06	1.25e-06	GO:0019226	transmission of nerve impulse
6.06	1.25e-06	GO:0035637	multicellular organismal signaling
6.41	1.76e-06	GO:0007268	synaptic transmission
3.09	2.66e-04	GO:0050877	neurological system process
3.94	6.26e-04	GO:0007267	cell-cell signaling
6.04	1.03e-03	GO:0007610	behavior
2.68	1.19e-03	GO:0003008	system process
3.32	1.80e-03	GO:0007154	cell communication
4.44	1.88e-02	GO:0006873	cellular ion homeostasis
4.29	2.58e-02	GO:0055082	cellular chemical homeostasis
4.10	3.87e-02	GO:0050801	ion homeostasis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
6.18	2.75e-06	GO:0045202	synapse
7.22	4.29e-06	GO:0044456	synapse part
21.22	5.24e-05	GO:0030672	synaptic vesicle membrane
6.77	1.01e-04	GO:0030659	cytoplasmic vesicle membrane
5.40	1.23e-04	GO:0043005	neuron projection
6.54	1.42e-04	GO:0012506	vesicle membrane
13.11	1.53e-04	GO:0030665	clathrin coated vesicle membrane
12.96	1.66e-04	GO:0008021	synaptic vesicle
4.20	3.83e-04	GO:0030054	cell junction
5.62	6.18e-04	GO:0044433	cytoplasmic vesicle part
3.72	8.28e-04	GO:0016023	cytoplasmic membrane-bounded vesicle
3.65	1.05e-03	GO:0031988	membrane-bounded vesicle
7.96	1.11e-03	GO:0030136	clathrin-coated vesicle
9.69	1.17e-03	GO:0030662	coated vesicle membrane
3.50	1.77e-03	GO:0031410	cytoplasmic vesicle
7.45	1.80e-03	GO:0043025	neuronal cell body
7.24	2.22e-03	GO:0044297	cell body
3.39	2.65e-03	GO:0031982	vesicle
6.50	4.82e-03	GO:0030135	coated vesicle
7.53	6.02e-03	GO:0045211	postsynaptic membrane
28.09	2.28e-02	GO:0032589	neuron projection membrane
79.57	3.45e-02	GO:0032590	dendrite membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
13.27	7.65e-04	GO:0005230	extracellular ligand-gated ion channel activity
16.94	1.42e-03	GO:0005231	excitatory extracellular ligand-gated ion channel activity
36.73	8.51e-03	GO:0016594	glycine binding
7.65	1.76e-02	GO:0015276	ligand-gated ion channel activity
7.65	1.76e-02	GO:0022834	ligand-gated channel activity
79.57	3.01e-02	GO:0016933	extracellular-glycine-gated ion channel activity
79.57	3.01e-02	GO:0016934	extracellular-glycine-gated chloride channel activity