Motif ID: REST.p3

Z-value: 0.993


Transcription factors associated with REST.p3:

Gene SymbolEntrez IDGene Name
REST 5978 RE1-silencing transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RESTchr4_+_57469122-0.214.4e-01Click!


Activity profile for motif REST.p3.

activity profile for motif REST.p3


Sorted Z-values histogram for motif REST.p3

Sorted Z-values for motif REST.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of REST.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 160 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_99599984 1.646 NM_001010917
 GOLGA7B
golgin A7 family, member B
chr20_+_30019465 1.272 NM_001011718
 XKR7
XK, Kell blood group complex subunit-related family, member 7
chr11_-_72170533 1.266 STARD10
StAR-related lipid transfer (START) domain containing 10
chr8_-_145530639 1.243 NM_031309
 SCRT1
scratch homolog 1, zinc finger protein (Drosophila)
chr12_+_46133 1.200 NM_001170738
 IQSEC3
IQ motif and Sec7 domain 3
chr3_-_48675321 1.064 NM_001407
 CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr19_+_45728270 1.021 SPTBN4
spectrin, beta, non-erythrocytic 4
chr19_+_45728207 1.014 NM_025213
 SPTBN4
spectrin, beta, non-erythrocytic 4
chr1_-_207892420 0.980 NM_000228
 LAMB3
laminin, beta 3
chr10_+_60607232 0.937 NM_001143774
 PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_+_116131889 0.780 NM_000608
 ORM2
orosomucoid 2
chr11_-_125278296 0.712 NM_031307
 PUS3
pseudouridylate synthase 3
chr7_+_145444385 0.704 NM_014141
 CNTNAP2
contactin associated protein-like 2
chrX_-_48943582 0.682 NM_003179
 SYP
synaptophysin
chr12_-_3472245 0.612 LOC100129223
hypothetical LOC100129223
chr20_-_61755145 0.585 NM_015894
 STMN3
stathmin-like 3
chr11_-_65871592 0.572 NM_006876
 B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr14_-_73962557 0.555 NM_001105579
 TMEM90A
transmembrane protein 90A
chr19_-_60383280 0.554 NM_003180
 SYT5
synaptotagmin V
chr6_+_43711532 0.544 NM_014628
 MAD2L1BP
MAD2L1 binding protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
6.41 1.76e-06 GO:0007268 synaptic transmission
6.06 1.25e-06 GO:0019226 transmission of nerve impulse
6.06 1.25e-06 GO:0035637 multicellular organismal signaling
6.04 1.03e-03 GO:0007610 behavior
4.44 1.88e-02 GO:0006873 cellular ion homeostasis
4.29 2.58e-02 GO:0055082 cellular chemical homeostasis
4.10 3.87e-02 GO:0050801 ion homeostasis
3.94 6.26e-04 GO:0007267 cell-cell signaling
3.32 1.80e-03 GO:0007154 cell communication
3.09 2.66e-04 GO:0050877 neurological system process
2.68 1.19e-03 GO:0003008 system process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
79.57 3.45e-02 GO:0032590 dendrite membrane
28.09 2.28e-02 GO:0032589 neuron projection membrane
21.22 5.24e-05 GO:0030672 synaptic vesicle membrane
13.11 1.53e-04 GO:0030665 clathrin coated vesicle membrane
12.96 1.66e-04 GO:0008021 synaptic vesicle
9.69 1.17e-03 GO:0030662 coated vesicle membrane
7.96 1.11e-03 GO:0030136 clathrin-coated vesicle
7.53 6.02e-03 GO:0045211 postsynaptic membrane
7.45 1.80e-03 GO:0043025 neuronal cell body
7.24 2.22e-03 GO:0044297 cell body
7.22 4.29e-06 GO:0044456 synapse part
6.77 1.01e-04 GO:0030659 cytoplasmic vesicle membrane
6.54 1.42e-04 GO:0012506 vesicle membrane
6.50 4.82e-03 GO:0030135 coated vesicle
6.18 2.75e-06 GO:0045202 synapse
5.62 6.18e-04 GO:0044433 cytoplasmic vesicle part
5.40 1.23e-04 GO:0043005 neuron projection
4.20 3.83e-04 GO:0030054 cell junction
3.72 8.28e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
3.65 1.05e-03 GO:0031988 membrane-bounded vesicle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
79.57 3.01e-02 GO:0016933 extracellular-glycine-gated ion channel activity
79.57 3.01e-02 GO:0016934 extracellular-glycine-gated chloride channel activity
36.73 8.51e-03 GO:0016594 glycine binding
16.94 1.42e-03 GO:0005231 excitatory extracellular ligand-gated ion channel activity
13.27 7.65e-04 GO:0005230 extracellular ligand-gated ion channel activity
7.65 1.76e-02 GO:0015276 ligand-gated ion channel activity
7.65 1.76e-02 GO:0022834 ligand-gated channel activity