Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 7.405


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFX3chr9_-_35159730.758.1e-04Click!
RFX2chr19_-_60614910.674.2e-03Click!
RFXANKchr19_+_19164649-0.601.5e-02Click!
RFX1chr19_-_139780960.572.2e-02Click!
RFX4chr12_+_105519049-0.341.9e-01Click!
RFXAPchr13_+_362913060.263.4e-01Click!
RFX5chr1_-_149586298-0.117.0e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_42701460 14.155 CCDC30
coiled-coil domain containing 30
chr14_+_105012106 12.799 NM_001312
 CRIP2
cysteine-rich protein 2
chr2_-_187422141 12.412 NM_182521
 ZSWIM2
zinc finger, SWIM-type containing 2
chr22_+_21817512 12.193 NM_004914
 RAB36
RAB36, member RAS oncogene family
chr15_+_68971835 11.033 NM_001199017
NM_017691
NM_001199018
 LRRC49


leucine rich repeat containing 49


chr15_-_68971665 10.726 NM_020147
 THAP10
THAP domain containing 10
chr19_+_59062962 9.466 MYADM
myeloid-associated differentiation marker
chr7_-_139987044 9.419 DENND2A
DENN/MADD domain containing 2A
chr5_-_14064846 9.357 DNAH5
dynein, axonemal, heavy chain 5
chr19_+_59062937 9.294 NM_001020819
NM_138373
 MYADM

myeloid-associated differentiation marker

chr11_-_65860450 9.206 NM_004292
 RIN1
Ras and Rab interactor 1
chr4_+_87734489 8.860 NM_006264
NM_080683
NM_080684
NM_080685
 PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr2_+_27046952 8.856 NM_012326
 MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr9_-_109291575 8.356 KLF4
Kruppel-like factor 4 (gut)
chr19_+_59062982 8.330 MYADM
myeloid-associated differentiation marker
chr11_+_102485293 8.151 NM_001080463
NM_001377
 DYNC2H1

dynein, cytoplasmic 2, heavy chain 1

chr9_-_109291866 7.994 NM_004235
 KLF4
Kruppel-like factor 4 (gut)
chr2_+_74502364 7.832 NM_032118
 WDR54
WD repeat domain 54
chr18_+_30544193 7.804 NM_001198941
NM_032978
 DTNA

dystrobrevin, alpha

chr17_-_61618276 7.683 NM_145036
 CCDC46
coiled-coil domain containing 46

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
13.44 1.69e-02 GO:0035082 axoneme assembly
8.36 4.74e-07 GO:0042384 cilium assembly
6.32 9.86e-06 GO:0060271 cilium morphogenesis
5.44 7.92e-08 GO:0030031 cell projection assembly
4.91 1.59e-04 GO:0010927 cellular component assembly involved in morphogenesis
3.62 1.75e-03 GO:0007018 microtubule-based movement
2.78 1.75e-04 GO:0007017 microtubule-based process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
11.94 7.82e-03 GO:0005952 cAMP-dependent protein kinase complex
8.31 1.41e-09 GO:0035085 cilium axoneme
7.82 1.79e-08 GO:0005932 microtubule basal body
7.05 6.52e-10 GO:0005930 axoneme
6.74 4.95e-10 GO:0044441 cilium part
4.89 7.20e-14 GO:0005929 cilium
4.57 1.66e-02 GO:0019861 flagellum
2.95 4.81e-07 GO:0005874 microtubule
2.56 2.73e-05 GO:0005815 microtubule organizing center
2.43 6.29e-10 GO:0015630 microtubule cytoskeleton
2.43 1.33e-02 GO:0005813 centrosome
2.30 1.69e-04 GO:0044463 cell projection part
1.76 1.93e-03 GO:0042995 cell projection
1.75 4.11e-07 GO:0005856 cytoskeleton
1.73 3.31e-04 GO:0044430 cytoskeletal part
1.41 7.37e-04 GO:0043228 non-membrane-bounded organelle
1.41 7.37e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.21 6.74e-06 GO:0005737 cytoplasm
1.11 8.72e-03 GO:0044424 intracellular part
1.10 1.95e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.12 2.30e-03 GO:0003777 microtubule motor activity
2.77 3.57e-02 GO:0003774 motor activity
1.46 3.22e-02 GO:0030554 adenyl nucleotide binding
1.46 4.16e-02 GO:0032559 adenyl ribonucleotide binding
1.42 2.36e-02 GO:0017076 purine nucleotide binding
1.40 4.42e-02 GO:0032553 ribonucleotide binding
1.40 4.42e-02 GO:0032555 purine ribonucleotide binding