Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 2.540


Transcription factors associated with LEF1_TCF7_TCF7L1,2.p2:

Gene SymbolEntrez IDGene Name
LEF1 51176 lymphoid enhancer-binding factor 1
TCF7 6932 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 83439 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF7L2chr10_+_1146999530.692.9e-03Click!
LEF1chr4_-_109307325-0.611.3e-02Click!
TCF7chr5_+_133478252-0.543.2e-02Click!
TCF7L1chr2_+_852138840.302.7e-01Click!


Activity profile for motif LEF1_TCF7_TCF7L1,2.p2.

activity profile for motif LEF1_TCF7_TCF7L1,2.p2


Sorted Z-values histogram for motif LEF1_TCF7_TCF7L1,2.p2

Sorted Z-values for motif LEF1_TCF7_TCF7L1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LEF1_TCF7_TCF7L1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_11597530 7.620 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr17_-_76985538 7.248


chr17_-_60986905 6.740 AXIN2
axin 2
chr6_-_128883125 6.415 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_-_120781002 6.146 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr13_+_75232797 5.193 NM_015842
LMO7
LIM domain 7
chr8_+_121892719 4.648


chr10_+_53744043 4.427 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr18_-_24011349 4.213 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr5_-_16791346 4.128 MYO10
myosin X
chr2_+_228386800 4.106 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr11_+_101488380 4.077 NM_001195045
YAP1
Yes-associated protein 1
chr18_-_24010944 4.077 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr5_-_58370693 3.813 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr7_-_27186400 3.778 NM_153715
HOXA10
homeobox A10
chr14_-_22521544 3.746 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr2_-_75641587 3.735 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr2_-_75641535 3.682 FAM176A
family with sequence similarity 176, member A
chr2_+_233443237 3.656 NM_206895
C2orf82
chromosome 2 open reading frame 82
chr6_-_138935359 3.643 NM_020464
NHSL1
NHS-like 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.43 3.71e-02 GO:0044421 extracellular region part

Nothing significant found in function category.