Motif ID: NFIX.p2

Z-value: 1.838


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
NFIX 4784 nuclear factor I/X (CCAAT-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIXchr19_+_129967450.741.1e-03Click!


Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_51025604 4.436 NM_001042481
FRMD6
FERM domain containing 6
chr1_-_150232900 4.091 S100A10
S100 calcium binding protein A10
chr21_+_32706615 4.068 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr1_-_150232927 4.062 S100A10
S100 calcium binding protein A10
chr1_-_150233337 3.861 NM_002966
S100A10
S100 calcium binding protein A10
chr10_+_88718167 3.348 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr5_+_148941228 3.231 NM_001001669
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr9_-_21549696 3.175 LOC554202
hypothetical LOC554202
chr17_-_68100537 3.130 LOC100499467
hypothetical LOC100499467
chr9_-_25668230 3.118 TUSC1
tumor suppressor candidate 1
chr5_+_178919298 2.882 NM_001040451
NM_001040452
RUFY1

RUN and FYVE domain containing 1

chr4_-_99798563 2.515 NM_005723
TSPAN5
tetraspanin 5
chr3_+_191714533 2.493 NM_001167928
NM_001167929
NM_001167930
NM_001167931
NM_002182
NM_134470
IL1RAP





interleukin 1 receptor accessory protein





chr7_-_80386258 2.462 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr22_+_44828338 2.461


chr15_+_61123327 2.451 TPM1
tropomyosin 1 (alpha)
chr7_-_80386602 2.435 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_+_17312654 2.414 VIM
vimentin
chr5_-_169340321 2.401 NM_001129891
FAM196B
family with sequence similarity 196, member B
chr17_-_25112393 2.361 SSH2
slingshot homolog 2 (Drosophila)
chr12_+_26239755 2.320 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr12_+_81604752 2.208 TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr9_+_77695334 2.202 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr1_+_199975674 2.163 NAV1
neuron navigator 1
chr9_+_111850770 2.139 AKAP2
A kinase (PRKA) anchor protein 2
chr3_-_41978464 2.076 NM_017886
ULK4
unc-51-like kinase 4 (C. elegans)
chr1_+_199975563 2.061 NM_001167738
NAV1
neuron navigator 1
chr1_-_205272619 2.051 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr21_-_27139563 2.032 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_+_53767251 2.016 LRRC1
leucine rich repeat containing 1
chr8_-_41286088 2.003 NM_003012
SFRP1
secreted frizzled-related protein 1
chr1_+_20788027 1.994 NM_001785
CDA
cytidine deaminase
chr12_+_26239535 1.970 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr3_-_46710137 1.959 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr4_-_75938710 1.937 NM_001729
BTC
betacellulin
chr4_+_146622154 1.929 NM_005900
SMAD1
SMAD family member 1
chr22_+_29974368 1.911 LIMK2
LIM domain kinase 2
chr1_+_63832067 1.895 NM_001172819
PGM1
phosphoglucomutase 1
chr4_-_83938920 1.895 NM_001037582
NM_024906
SCD5

stearoyl-CoA desaturase 5

chr12_+_81605032 1.883 NM_152588
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr14_-_104507862 1.882 AHNAK2
AHNAK nucleoprotein 2
chr1_+_208569262 1.879 NM_001170580
HHAT
hedgehog acyltransferase
chr9_+_111850698 1.862 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr10_+_102782151 1.842 SFXN3
sideroflexin 3
chr2_+_241023703 1.799 NM_002081
GPC1
glypican 1
chr10_+_124210980 1.776 NM_002775
HTRA1
HtrA serine peptidase 1
chr2_+_241023880 1.717


chr1_+_208568811 1.712 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr6_+_30959839 1.689 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr5_+_96024434 1.685 CAST
calpastatin
chr6_-_26125939 1.646 NM_005325
HIST1H1A
histone cluster 1, H1a
chr10_+_17311962 1.634 VIM
vimentin
chr10_-_17311961 1.619


chr9_+_111582317 1.595 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr9_+_70926205 1.568 TJP2
tight junction protein 2 (zona occludens 2)
chr17_-_5428491 1.550 NM_001033053
NM_014922
NM_033004
NM_033006
NM_033007
NLRP1




NLR family, pyrin domain containing 1




chr13_-_100866839 1.485 NALCN
sodium leak channel, non-selective
chr3_+_185762233 1.466 NM_004443
EPHB3
EPH receptor B3
chr9_-_25668855 1.440 NM_001004125
TUSC1
tumor suppressor candidate 1
chr10_-_105982052 1.430 NM_025145
WDR96
WD repeat domain 96
chr10_+_17311788 1.427 VIM
vimentin
chr22_+_29974314 1.424 NM_001031801
NM_016733
LIMK2

LIM domain kinase 2

chr3_-_162305319 1.420 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr9_+_70926009 1.398 NM_001170414
TJP2
tight junction protein 2 (zona occludens 2)
chr21_-_27139143 1.386 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr15_+_61122957 1.376 TPM1
tropomyosin 1 (alpha)
chr10_+_124211353 1.350 HTRA1
HtrA serine peptidase 1
chr12_+_54612055 1.340 NM_201444
NM_201445
NM_201554
DGKA


diacylglycerol kinase, alpha 80kDa


chr1_-_206484258 1.334 NM_025179
PLXNA2
plexin A2
chr6_+_3696224 1.322


chr3_+_32408346 1.316 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr10_+_122206455 1.312 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr2_-_162883062 1.281 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr12_+_6179736 1.276 NM_001769
CD9
CD9 molecule
chr2_+_37425240 1.264 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr22_+_38720881 1.258 NM_138435
FAM83F
family with sequence similarity 83, member F
chr9_+_123070276 1.255 GSN
gelsolin
chr17_+_72795567 1.253 NM_001113492
SEPT9
septin 9
chr5_-_156935283 1.253


chr1_+_43386180 1.244 NM_001101376
FAM183A
family with sequence similarity 183, member A
chr4_+_158216631 1.200 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr17_+_35587767 1.187 NM_016339
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr19_+_45807909 1.186


chr9_-_83493415 1.176 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr5_-_156935317 1.174 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr16_+_65765256 1.167 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr1_-_68470585 1.165 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr3_+_32408155 1.165 NM_138410
NM_181472
CMTM7

CKLF-like MARVEL transmembrane domain containing 7

chr13_-_76358370 1.162 KCTD12
potassium channel tetramerisation domain containing 12
chr19_-_19599973 1.156 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr13_-_100866706 1.148 NM_052867
NALCN
sodium leak channel, non-selective
chr14_+_104785898 1.143 NM_033271
BTBD6
BTB (POZ) domain containing 6
chr15_-_29070909 1.138 NM_017762
MTMR10
myotubularin related protein 10
chr9_-_112840801 1.138 LPAR1
lysophosphatidic acid receptor 1
chr8_-_101227203 1.130 NM_001029860
FBXO43
F-box protein 43
chr4_+_148621518 1.127 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr1_+_148521852 1.127 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr4_-_143987053 1.125 NM_001101669
NM_003866
INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr12_+_62523648 1.121


chr9_+_123070234 1.120 GSN
gelsolin
chr21_-_43671355 1.110 NM_173354
SIK1
salt-inducible kinase 1
chr1_+_78858675 1.110 NM_006820
IFI44L
interferon-induced protein 44-like
chr9_-_129656413 1.106 ENG
endoglin
chr9_-_111300350 1.105 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr11_+_34599227 1.100 EHF
ets homologous factor
chr7_+_65307816 1.096 TPST1
tyrosylprotein sulfotransferase 1
chr9_+_123070191 1.093 NM_001127662
NM_001127663
NM_001127664
NM_001127665
NM_001127666
NM_001127667
NM_198252
GSN






gelsolin






chr10_-_101759630 1.082 NM_015221
DNMBP
dynamin binding protein
chr11_+_122258600 1.077 NM_024806
NM_199124
C11orf63

chromosome 11 open reading frame 63

chr11_+_112690460 1.075 NM_017868
TTC12
tetratricopeptide repeat domain 12
chr4_+_89597257 1.066 NM_016323
HERC5
hect domain and RLD 5
chr2_-_40532651 1.066 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_+_89409332 1.063 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr4_-_177353707 1.060 NM_144644
SPATA4
spermatogenesis associated 4
chr1_+_31658549 1.051 NM_178865
SERINC2
serine incorporator 2
chr1_-_72520735 1.051 NM_173808
NEGR1
neuronal growth regulator 1
chr10_-_123346148 1.034 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr20_+_17498507 1.025 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr1_+_891739 1.014 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr2_-_127694123 1.009 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr4_+_148621694 1.002 EDNRA
endothelin receptor type A
chr6_+_86216020 0.998 NM_002526
NT5E
5'-nucleotidase, ecto (CD73)
chr4_+_166097548 0.995 NM_153027
C4orf39
chromosome 4 open reading frame 39
chr14_+_104785936 0.993 BTBD6
BTB (POZ) domain containing 6
chr1_+_31659246 0.985 NM_001199039
NM_018565
SERINC2

serine incorporator 2

chr12_+_106236281 0.979 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr3_-_197103848 0.970 TNK2
tyrosine kinase, non-receptor, 2
chr15_-_58477407 0.947 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr1_-_151855413 0.940 NM_020672
S100A14
S100 calcium binding protein A14
chr15_-_68971665 0.935 NM_020147
THAP10
THAP domain containing 10
chr11_-_11986704 0.933 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr12_+_74160779 0.926 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr3_+_44571600 0.926 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr2_-_56266408 0.923 LOC100129434
hypothetical LOC100129434
chr12_+_54611212 0.919 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr1_-_94779727 0.909 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr8_+_79740813 0.906 NM_016010
FAM164A
family with sequence similarity 164, member A
chr9_+_5440455 0.905 NM_014143
CD274
CD274 molecule
chr10_-_128884411 0.900 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr16_+_65790514 0.897 NM_024712
ELMO3
engulfment and cell motility 3
chr8_-_119192985 0.888 NM_000127
EXT1
exostosin 1
chr6_+_86216457 0.883 NT5E
5'-nucleotidase, ecto (CD73)
chr11_+_10428799 0.882 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr4_+_166097579 0.877 C4orf39
chromosome 4 open reading frame 39
chr20_-_42272709 0.876 C20orf111
chromosome 20 open reading frame 111
chr6_-_150285838 0.869 NM_001001788
RAET1G
retinoic acid early transcript 1G
chr9_-_129656581 0.868 ENG
endoglin
chr8_+_143778529 0.859 NM_001160354
NM_001160355
NM_017527
LY6K


lymphocyte antigen 6 complex, locus K


chr11_+_93501811 0.856 PANX1
pannexin 1
chr1_-_23393808 0.853 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr6_+_49626431 0.847


chr17_+_21128625 0.845 MAP2K3
mitogen-activated protein kinase kinase 3
chr13_-_76358433 0.845 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr7_+_33911636 0.844 NM_133468
BMPER
BMP binding endothelial regulator
chr4_+_152549776 0.836 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr1_+_43769065 0.817 NM_002840
NM_130440
PTPRF

protein tyrosine phosphatase, receptor type, F

chr7_+_65307691 0.804 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr1_-_159257595 0.796 NM_016946
F11R
F11 receptor
chr5_-_111121150 0.795 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr15_+_38849450 0.789 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr1_+_24701886 0.775 NM_013441
RCAN3
RCAN family member 3
chr3_-_28365510 0.771 NM_001134432
NM_001134433
NM_022461
AZI2


5-azacytidine induced 2


chr3_+_132228383 0.767 NM_001146003
NM_024800
NM_145910
NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr10_+_71232281 0.763 COL13A1
collagen, type XIII, alpha 1
chr4_+_148621567 0.760 EDNRA
endothelin receptor type A
chr1_+_156417302 0.749 CD1D
CD1d molecule
chr4_-_11039600 0.745 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr9_-_73573121 0.740 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr4_+_75699652 0.736 NM_001657
AREG
amphiregulin
chr17_-_28228184 0.733 MYO1D
myosin ID
chr2_+_241023908 0.720 GPC1
glypican 1
chr14_+_58174489 0.716 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr15_+_65145248 0.714 NM_005902
SMAD3
SMAD family member 3
chr6_+_49626317 0.712 C6orf141
chromosome 6 open reading frame 141
chr20_-_42272837 0.712 NM_016470
C20orf111
chromosome 20 open reading frame 111
chr17_+_21128560 0.709 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr17_+_21128614 0.705 MAP2K3
mitogen-activated protein kinase kinase 3
chr14_+_23575460 0.698 NM_001082488
DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 1
chr16_+_3010311 0.696 NM_016639
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr10_-_91001496 0.691 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr3_+_129117007 0.686 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr8_-_7200278 0.685 FAM66B
family with sequence similarity 66, member B
chr12_-_41269679 0.677 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr5_-_37285160 0.665 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr9_-_129656778 0.662 ENG
endoglin
chr19_-_61680510 0.658 NM_022103
ZNF667
zinc finger protein 667
chr8_-_33544184 0.656 NM_024787
RNF122
ring finger protein 122
chr11_-_119514058 0.654 NM_012101
TRIM29
tripartite motif containing 29
chr11_-_119514011 0.653 TRIM29
tripartite motif containing 29
chr18_-_20231783 0.647 NM_080597
OSBPL1A
oxysterol binding protein-like 1A
chr5_-_111120929 0.646 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr11_+_27019084 0.643 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chrX_-_68301974 0.638 NM_001032396
NM_022368
NM_145119
PJA1


praja ring finger 1


chr11_-_119513948 0.638 TRIM29
tripartite motif containing 29
chr6_-_150431864 0.637 NM_024518
ULBP3
UL16 binding protein 3
chr9_+_115382760 0.633 NM_021106
RGS3
regulator of G-protein signaling 3
chr10_-_31360778 0.632 NM_001143766
NM_001143767
NM_001143768
NM_001143770
NM_001143771
NM_182755
ZNF438





zinc finger protein 438





chr1_-_86634511 0.631 NM_001007022
NM_001184765
NM_001184766
NM_020729
ODF2L



outer dense fiber of sperm tails 2-like



chr9_-_129656830 0.626 NM_000118
NM_001114753
ENG

endoglin

chr5_-_59819642 0.624 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 1.82e-02 GO:0005737 cytoplasm
2.24 3.26e-02 GO:0070161 anchoring junction
2.29 4.24e-02 GO:0005912 adherens junction

Nothing significant found in function category.