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Motif ID: TLX2.p2

Z-value: 1.244

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_169789327	1.254	NM_001166109	PALLD	palladin, cytoskeletal associated protein
chr20_-_14266200	1.117	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr5_+_36642213	0.916	NM_001166696 NM_004172	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_-_46593923	0.857	NM_001040084 NM_001098845	ANXA8L2 LOC653110 ANXA8 ANXA8L1	annexin A8-like 2 hypothetical LOC653110 annexin A8 annexin A8-like 1
chr13_-_98428244	0.847	NM_001130048 NM_001130050	DOCK9	dedicator of cytokinesis 9
chr12_-_41269679	0.846	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr10_+_63803921	0.828	NM_014951 NM_199450 NM_199451	ZNF365	zinc finger protein 365
chr3_+_113534604	0.797	NM_001004196 NM_005944	CD200	CD200 molecule
chr6_-_139654807	0.780	NM_153235	TXLNB	taxilin beta
chr10_+_47875229	0.768	NM_001040084 NM_001098845	ANXA8L2 ANXA8 ANXA8L1	annexin A8-like 2 annexin A8 annexin A8-like 1
chr4_-_35922288	0.763	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_+_36642424	0.753		SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_16650687	0.745		LMO3	LIM domain only 3 (rhombotin-like 2)
chrX_+_48221323	0.721	NM_177434	FTSJ1	FtsJ homolog 1 (E. coli)
chr10_+_86174665	0.706		FAM190B	family with sequence similarity 190, member B
chr12_-_16650697	0.700	NM_018640	LMO3	LIM domain only 3 (rhombotin-like 2)
chr3_+_42107711	0.686	NM_001042646	TRAK1	trafficking protein, kinesin binding 1
chr6_+_116798791	0.678	NM_013352	DSE	dermatan sulfate epimerase
chr1_-_6368324	0.669	NM_181864	ACOT7	acyl-CoA thioesterase 7
chr11_-_127897098	0.668		ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr1_+_86662356	0.665	NM_006536	CLCA2	chloride channel accessory 2
chr11_+_113435640	0.657	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr10_+_47216925	0.652	NM_001630	ANXA8L2 ANXA8	annexin A8-like 2 annexin A8
chr13_-_40491491	0.644	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr3_-_145049853	0.634	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr18_+_54013575	0.609	NM_001144970	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr3_+_113534710	0.599		CD200	CD200 molecule
chr2_-_188021117	0.573	NM_005795	CALCRL	calcitonin receptor-like
chr13_-_29321599	0.565		UBL3	ubiquitin-like 3
chr8_+_32905027	0.561
chr12_+_52618815	0.556	NM_017410	HOXC13	homeobox C13
chr13_-_40491405	0.550		ELF1	E74-like factor 1 (ets domain transcription factor)
chrX_-_19727775	0.540		SH3KBP1	SH3-domain kinase binding protein 1
chr7_-_80386258	0.539		SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_+_52653176	0.535	NM_014212	HOXC11	homeobox C11
chr12_+_74160779	0.531	NM_006851	GLIPR1	GLI pathogenesis-related 1
chr3_-_15814678	0.526	NM_001195098	ANKRD28	ankyrin repeat domain 28
chr12_+_84198015	0.525	NM_006982	ALX1	ALX homeobox 1
chr4_-_90977149	0.522	NM_001146054 NM_007308 NM_000345	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chrX_-_19727828	0.513	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr6_-_165995510	0.513	NM_001130690 NM_006661	PDE10A	phosphodiesterase 10A
chr2_-_189752575	0.510	NM_000393	COL5A2	collagen, type V, alpha 2
chr10_+_24795446	0.510		KIAA1217	KIAA1217
chr10_+_80672842	0.510		ZMIZ1	zinc finger, MIZ-type containing 1
chr19_+_627346	0.509	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr6_+_54819527	0.508	NM_001010872	FAM83B	family with sequence similarity 83, member B
chr13_-_32757835	0.505	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr12_+_32578513	0.504		FGD4	FYVE, RhoGEF and PH domain containing 4
chr5_+_96023926	0.493		CAST	calpastatin
chr7_-_87687276	0.491		SRI	sorcin
chr7_-_87687302	0.491	NM_003130	SRI	sorcin
chr11_+_86189138	0.473	NM_007173	PRSS23	protease, serine, 23
chr6_-_31658044	0.472	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr5_+_96023627	0.472	NM_001042440	CAST	calpastatin
chr1_+_208178160	0.472	NM_001146261 NM_001146262 NM_001146264 NM_153262	SYT14	synaptotagmin XIV
chr10_+_24795465	0.469		KIAA1217	KIAA1217
chr7_+_73145481	0.465		LIMK1	LIM domain kinase 1
chr16_-_66827449	0.464	NM_024939	ESRP2	epithelial splicing regulatory protein 2
chr14_+_64240996	0.464		PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr22_-_37969897	0.463		PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr12_+_52697160	0.458		HOXC5 HOXC6	homeobox C5 homeobox C6
chr11_+_35117408	0.457		CD44	CD44 molecule (Indian blood group)
chr11_-_8572321	0.453		STK33	serine/threonine kinase 33
chr12_+_52696908	0.451	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr5_+_96023479	0.450	NM_001190442	CAST	calpastatin
chr1_-_114215768	0.449	NM_001193431 NM_012411 NM_015967	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr12_+_32546243	0.448	NM_139241	FGD4	FYVE, RhoGEF and PH domain containing 4
chr11_+_35117391	0.445		CD44	CD44 molecule (Indian blood group)
chr7_-_22363036	0.444	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr5_+_125786975	0.437		GRAMD3	GRAM domain containing 3
chr3_-_180272229	0.437		ZMAT3	zinc finger, matrin-type 3
chr1_-_201321711	0.435		MYOG	myogenin (myogenic factor 4)
chr14_+_64240902	0.431	NM_015549	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_-_127897271	0.428	NM_001162422 NM_005238	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr5_+_148631588	0.427	NM_001146337 NM_152406	AFAP1L1	actin filament associated protein 1-like 1
chr3_+_123279439	0.426	NM_006889	CD86	CD86 molecule
chr17_+_35425139	0.426	NM_000759 NM_001178147 NM_172219 NM_172220	CSF3	colony stimulating factor 3 (granulocyte)
chr7_+_90063543	0.425		CDK14	cyclin-dependent kinase 14
chr3_-_150533948	0.419	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr6_+_32713160	0.415	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr3_+_113061330	0.414		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr6_-_33862690	0.413	NM_001143944	LEMD2	LEM domain containing 2
chr20_-_43316597	0.412	NM_003064	SLPI	secretory leukocyte peptidase inhibitor
chr13_-_105985313	0.412	NM_004093	EFNB2	ephrin-B2
chr3_-_150578023	0.411		TM4SF1	transmembrane 4 L six family member 1
chr18_+_54682261	0.410		ZNF532	zinc finger protein 532
chr11_-_33700831	0.401	NM_001127223 NM_001127225 NM_001127226	CD59	CD59 molecule, complement regulatory protein
chr4_-_159313613	0.399	NM_001031700 NM_001128424	FAM198B	family with sequence similarity 198, member B
chr3_+_113061296	0.399		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr12_-_94135154	0.396	NM_018351	FGD6	FYVE, RhoGEF and PH domain containing 6
chr6_-_46728188	0.396	NM_016593	CYP39A1	cytochrome P450, family 39, subfamily A, polypeptide 1
chr3_-_114176401	0.394	NM_138806 NM_138939 NM_138940 NM_170780	CD200R1	CD200 receptor 1
chr11_+_12265022	0.393	NM_032867	MICALCL	MICAL C-terminal like
chr3_-_184363126	0.392		LAMP3	lysosomal-associated membrane protein 3
chr1_+_111573855	0.391	NM_001025199	CHI3L2	chitinase 3-like 2
chr3_-_180272291	0.390	NM_022470 NM_152240	ZMAT3	zinc finger, matrin-type 3
chr1_+_208178198	0.387		SYT14	synaptotagmin XIV
chr5_-_156935283	0.386
chr3_+_115258270	0.386	NM_024638	QTRTD1	queuine tRNA-ribosyltransferase domain containing 1
chr22_+_29974368	0.386		LIMK2	LIM domain kinase 2
chr3_-_109292444	0.378	NM_001777 NM_198793	CD47	CD47 molecule
chr1_+_26744929	0.377	NM_001006665	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_-_225519974	0.375		DOCK10	dedicator of cytokinesis 10
chr6_-_32665409	0.375	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr8_-_18710575	0.371	NM_206909	PSD3	pleckstrin and Sec7 domain containing 3
chr14_+_85066207	0.371	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr1_+_32777556	0.370		ZBTB8A	zinc finger and BTB domain containing 8A
chr1_-_68470585	0.368	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr16_+_28797309	0.368	NM_004320 NM_173201	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_+_59979857	0.367	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr5_-_156935317	0.365	NM_033274	ADAM19	ADAM metallopeptidase domain 19
chr12_+_439803	0.364	NM_173593	B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3
chr10_-_96112609	0.362	NM_022451	NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)
chr11_-_8572277	0.362		STK33	serine/threonine kinase 33
chr9_+_119506446	0.361		TLR4	toll-like receptor 4
chr20_+_43875078	0.361	NM_181801	UBE2C	ubiquitin-conjugating enzyme E2C
chr13_-_32658215	0.359	NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr4_-_111777584	0.358		PITX2	paired-like homeodomain 2
chr3_+_48482625	0.358		TREX1	three prime repair exonuclease 1
chrX_+_15428820	0.357	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr10_+_96295511	0.357	NM_018063	HELLS	helicase, lymphoid-specific
chr1_+_151147646	0.355	NM_005547	IVL	involucrin
chrX_+_38305634	0.353	NM_004615	TSPAN7	tetraspanin 7
chr5_+_177473071	0.351	NM_015111	N4BP3	NEDD4 binding protein 3
chr6_-_32742265	0.349	NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr9_-_23816062	0.348	NM_004432	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_+_56265260	0.348
chr1_+_160002733	0.348		ATF6	activating transcription factor 6
chr10_-_33663305	0.347		NRP1	neuropilin 1
chr1_+_160002746	0.346		ATF6	activating transcription factor 6
chr22_+_41877502	0.345		TSPO	translocator protein (18kDa)
chr12_-_6830667	0.345	NM_031299	CDCA3	cell division cycle associated 3
chr22_-_44015248	0.345	NM_001009880	KIAA0930	KIAA0930
chr15_-_58477407	0.343	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr12_-_53071285	0.342	NM_001130967 NM_001130968	ZNF385A	zinc finger protein 385A
chr3_+_115258348	0.340		QTRTD1	queuine tRNA-ribosyltransferase domain containing 1
chrX_-_106846253	0.337	NM_001015881	TSC22D3	TSC22 domain family, member 3
chr12_-_102758913	0.335		NT5DC3	5'-nucleotidase domain containing 3
chr1_+_36409277	0.333		MAP7D1	MAP7 domain containing 1
chr18_-_22383066	0.332	NM_001136205	KCTD1	potassium channel tetramerisation domain containing 1
chr17_+_44927591	0.332	NM_002507	NGFR	nerve growth factor receptor
chr5_+_68746694	0.331	NM_001038603	MARVELD2	MARVEL domain containing 2
chr1_+_26744893	0.331		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_78391178	0.331	NM_024702	ZNF750	zinc finger protein 750
chr8_-_10550026	0.329	NM_178857	RP1L1	retinitis pigmentosa 1-like 1
chr12_-_52960146	0.326		CBX5	chromobox homolog 5
chr17_-_3740785	0.326	NM_172206	CAMKK1	calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr2_+_219141761	0.326	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr7_-_32076985	0.323	NM_001191056 NM_001191057	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr20_+_56318415	0.322		RAB22A	RAB22A, member RAS oncogene family
chr6_-_112033752	0.322		TRAF3IP2	TRAF3 interacting protein 2
chr4_+_120276386	0.318	NM_016599	MYOZ2	myozenin 2
chr4_-_99798563	0.318	NM_005723	TSPAN5	tetraspanin 5
chr15_-_32289561	0.315	NM_024713	C15orf29	chromosome 15 open reading frame 29
chr18_+_50646616	0.315	NM_004163	RAB27B	RAB27B, member RAS oncogene family
chr11_+_113435506	0.315		ZBTB16	zinc finger and BTB domain containing 16
chr7_-_92303812	0.314		CDK6	cyclin-dependent kinase 6
chr19_-_48976852	0.314		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr9_-_33437527	0.313	NM_004925	AQP3	aquaporin 3 (Gill blood group)
chr12_-_52960206	0.312		CBX5	chromobox homolog 5
chr10_+_49279647	0.312	NM_002750 NM_139046 NM_139047 NM_139049	MAPK8	mitogen-activated protein kinase 8
chr12_-_52960168	0.311	NM_012117	CBX5	chromobox homolog 5
chr12_+_15955549	0.310		DERA	deoxyribose-phosphate aldolase (putative)
chr18_+_27281729	0.309	NM_001944	DSG3	desmoglein 3
chr8_+_86563382	0.309	NM_000067	CA2	carbonic anhydrase II
chr7_-_150960086	0.309	NM_024429	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr1_-_219982016	0.309		DUSP10	dual specificity phosphatase 10
chr6_-_159159186	0.308		EZR	ezrin
chr5_+_152850276	0.307	NM_000827 NM_001114183	GRIA1	glutamate receptor, ionotropic, AMPA 1
chr1_+_160002693	0.307	NM_007348	ATF6	activating transcription factor 6
chr1_-_31003181	0.305		LAPTM5	lysosomal protein transmembrane 5
chr3_+_48482213	0.304	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr3_+_69216747	0.303	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr22_+_41877470	0.303	NM_000714 NM_007311	TSPO	translocator protein (18kDa)
chr14_-_64508547	0.303	NM_198686	RAB15	RAB15, member RAS onocogene family
chr7_-_32077504	0.303	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr3_-_21767819	0.302	NM_024697	ZNF385D	zinc finger protein 385D
chr8_-_127639647	0.302		FAM84B	family with sequence similarity 84, member B
chr12_-_44948976	0.301		SLC38A1	solute carrier family 38, member 1
chr1_-_231498081	0.300	NM_014801	PCNXL2	pecanex-like 2 (Drosophila)
chr7_+_114350144	0.300		MDFIC	MyoD family inhibitor domain containing
chr19_-_14951349	0.300		SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr6_-_112033775	0.300		TRAF3IP2	TRAF3 interacting protein 2
chr1_-_219982081	0.299	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr2_-_40593074	0.299	NM_001112802	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_+_24518398	0.298	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr18_+_59733724	0.298	NM_005024	SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_-_25164061	0.297	NM_001031680	RUNX3	runt-related transcription factor 3
chr18_+_19287283	0.297		RIOK3	RIO kinase 3 (yeast)
chr10_+_82163568	0.296		C10orf58	chromosome 10 open reading frame 58
chr3_-_152517204	0.295	NM_023915	GPR87	G protein-coupled receptor 87
chr12_-_32940931	0.295	NM_001005242 NM_004572	PKP2	plakophilin 2
chr12_-_44949046	0.294		SLC38A1	solute carrier family 38, member 1
chr20_+_36867708	0.294	NM_001172735 NM_015568	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr3_-_184363157	0.293	NM_014398	LAMP3	lysosomal-associated membrane protein 3
chr5_-_102483680	0.293	NM_017676	GIN1	gypsy retrotransposon integrase 1
chr16_-_87535106	0.292	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr8_+_120289735	0.291	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr1_-_219982049	0.291		DUSP10	dual specificity phosphatase 10
chr1_+_195179533	0.290	NM_005666	CFHR2	complement factor H-related 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.65	1.68e-04	GO:0019058	viral infectious cycle
3.01	9.49e-04	GO:0019080	viral genome expression
3.01	9.49e-04	GO:0019083	viral transcription
1.73	1.93e-03	GO:0043068	positive regulation of programmed cell death
2.91	2.00e-03	GO:0006415	translational termination
1.72	2.90e-03	GO:0043065	positive regulation of apoptosis
2.73	2.94e-03	GO:0006414	translational elongation
2.34	3.16e-03	GO:0022415	viral reproductive process
1.70	3.90e-03	GO:0010942	positive regulation of cell death
2.74	4.32e-03	GO:0043241	protein complex disassembly
2.74	4.32e-03	GO:0043624	cellular protein complex disassembly
2.62	4.63e-03	GO:0032984	macromolecular complex disassembly
2.62	4.63e-03	GO:0034623	cellular macromolecular complex disassembly
2.11	2.20e-02	GO:0022411	cellular component disassembly
2.11	2.20e-02	GO:0071845	cellular component disassembly at cellular level
1.26	2.30e-02	GO:0048518	positive regulation of biological process
6.15	2.47e-02	GO:0006607	NLS-bearing substrate import into nucleus
1.12	3.93e-02	GO:0065007	biological regulation
1.12	4.61e-02	GO:0050789	regulation of biological process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.31	2.51e-05	GO:0043228	non-membrane-bounded organelle
1.31	2.51e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.13	2.26e-04	GO:0005737	cytoplasm
2.97	9.08e-04	GO:0022626	cytosolic ribosome
1.16	2.62e-03	GO:0044422	organelle part
1.21	4.03e-03	GO:0032991	macromolecular complex
1.15	5.70e-03	GO:0044446	intracellular organelle part
1.33	8.32e-03	GO:0005856	cytoskeleton
1.26	1.50e-02	GO:0044459	plasma membrane part
3.51	1.59e-02	GO:0022625	cytosolic large ribosomal subunit
1.22	2.12e-02	GO:0043234	protein complex
1.97	2.75e-02	GO:0005840	ribosome
1.26	3.10e-02	GO:0005829	cytosol
1.75	3.13e-02	GO:0015629	actin cytoskeleton
1.08	3.17e-02	GO:0043226	organelle
2.79	3.21e-02	GO:0015934	large ribosomal subunit
1.08	3.46e-02	GO:0043229	intracellular organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	8.05e-05	GO:0005515	protein binding
2.23	6.24e-03	GO:0003735	structural constituent of ribosome