Motif ID: TLX2.p2

Z-value: 1.244


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX2chr2_+_74594093-0.292.7e-01Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_169789327 1.254 NM_001166109
 PALLD
palladin, cytoskeletal associated protein
chr20_-_14266200 1.117 NM_013281
NM_198391
 FLRT3

fibronectin leucine rich transmembrane protein 3

chr5_+_36642213 0.916 NM_001166696
NM_004172
 SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr10_-_46593923 0.857 NM_001040084
NM_001098845
 ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr13_-_98428244 0.847 NM_001130048
NM_001130050
 DOCK9

dedicator of cytokinesis 9

chr12_-_41269679 0.846 NM_153026
 PRICKLE1
prickle homolog 1 (Drosophila)
chr10_+_63803921 0.828 NM_014951
NM_199450
NM_199451
 ZNF365


zinc finger protein 365


chr3_+_113534604 0.797 NM_001004196
NM_005944
 CD200

CD200 molecule

chr6_-_139654807 0.780 NM_153235
 TXLNB
taxilin beta
chr10_+_47875229 0.768 NM_001040084
NM_001098845
 ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr4_-_35922288 0.763 NM_015230
 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_+_36642424 0.753 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_16650687 0.745 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_48221323 0.721 NM_177434
 FTSJ1
FtsJ homolog 1 (E. coli)
chr10_+_86174665 0.706 FAM190B
family with sequence similarity 190, member B
chr12_-_16650697 0.700 NM_018640
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_42107711 0.686 NM_001042646
 TRAK1
trafficking protein, kinesin binding 1
chr6_+_116798791 0.678 NM_013352
 DSE
dermatan sulfate epimerase
chr1_-_6368324 0.669 NM_181864
 ACOT7
acyl-CoA thioesterase 7
chr11_-_127897098 0.668 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
6.15 2.47e-02 GO:0006607 NLS-bearing substrate import into nucleus
3.01 9.49e-04 GO:0019080 viral genome expression
3.01 9.49e-04 GO:0019083 viral transcription
2.91 2.00e-03 GO:0006415 translational termination
2.74 4.32e-03 GO:0043241 protein complex disassembly
2.74 4.32e-03 GO:0043624 cellular protein complex disassembly
2.73 2.94e-03 GO:0006414 translational elongation
2.65 1.68e-04 GO:0019058 viral infectious cycle
2.62 4.63e-03 GO:0032984 macromolecular complex disassembly
2.62 4.63e-03 GO:0034623 cellular macromolecular complex disassembly
2.34 3.16e-03 GO:0022415 viral reproductive process
2.11 2.20e-02 GO:0022411 cellular component disassembly
2.11 2.20e-02 GO:0071845 cellular component disassembly at cellular level
1.73 1.93e-03 GO:0043068 positive regulation of programmed cell death
1.72 2.90e-03 GO:0043065 positive regulation of apoptosis
1.70 3.90e-03 GO:0010942 positive regulation of cell death
1.26 2.30e-02 GO:0048518 positive regulation of biological process
1.12 3.93e-02 GO:0065007 biological regulation
1.12 4.61e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
3.51 1.59e-02 GO:0022625 cytosolic large ribosomal subunit
2.97 9.08e-04 GO:0022626 cytosolic ribosome
2.79 3.21e-02 GO:0015934 large ribosomal subunit
1.97 2.75e-02 GO:0005840 ribosome
1.75 3.13e-02 GO:0015629 actin cytoskeleton
1.33 8.32e-03 GO:0005856 cytoskeleton
1.31 2.51e-05 GO:0043228 non-membrane-bounded organelle
1.31 2.51e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.26 1.50e-02 GO:0044459 plasma membrane part
1.26 3.10e-02 GO:0005829 cytosol
1.22 2.12e-02 GO:0043234 protein complex
1.21 4.03e-03 GO:0032991 macromolecular complex
1.16 2.62e-03 GO:0044422 organelle part
1.15 5.70e-03 GO:0044446 intracellular organelle part
1.13 2.26e-04 GO:0005737 cytoplasm
1.08 3.17e-02 GO:0043226 organelle
1.08 3.46e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.23 6.24e-03 GO:0003735 structural constituent of ribosome
1.15 8.05e-05 GO:0005515 protein binding