Motif ID: AR.p2

Z-value: 0.622


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARchrX_+_66680593-0.204.6e-01Click!


Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_149778815 1.840 GIMAP8
GTPase, IMAP family member 8
chr7_+_149778869 1.646 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr1_-_154727014 1.446 MEF2D
myocyte enhancer factor 2D
chr3_+_52254782 1.369 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr12_+_111900650 1.056 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr1_-_200396328 0.875 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr2_-_231498184 0.779 NM_005683
GPR55
G protein-coupled receptor 55
chr14_-_105796665 0.707 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr2_+_134728299 0.701 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr1_+_149395728 0.689 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr10_+_70517823 0.572 NM_002727
SRGN
serglycin
chr11_+_63730720 0.568 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr1_-_200396354 0.557 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr14_-_105796268 0.545 ZCWPW2
IGHV3-23
IGKV3-20
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
chr14_-_105763152 0.543 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_-_37480898 0.526 SUN2
Sad1 and UNC84 domain containing 2
chr1_-_27825633 0.508 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr14_-_106289751 0.506 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr18_+_70317548 0.499 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr14_-_106202262 0.460 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr1_-_1139358 0.444 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr19_+_17499064 0.439 FAM129C
family with sequence similarity 129, member C
chr14_-_64416307 0.431 SPTB
spectrin, beta, erythrocytic
chr4_+_186301410 0.416 NM_001151
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr14_-_105862080 0.383 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr14_-_105762742 0.377


chr5_-_176869943 0.318 NM_001144875
NM_001144876
DOK3

docking protein 3

chr14_-_106064887 0.312 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr6_-_6265896 0.311 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr15_-_38185578 0.298 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr5_-_149772469 0.278 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr14_-_105644300 0.266 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr1_-_149004852 0.249 CTSS
cathepsin S
chr14_-_105997732 0.248 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_142670624 0.233 NM_001143679
NM_001143680
NM_001143681
NM_015917
GSTK1



glutathione S-transferase kappa 1



chr6_-_6265874 0.233 F13A1
coagulation factor XIII, A1 polypeptide
chr1_-_155053124 0.224 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr18_-_46600295 0.221 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr16_-_727889 0.209 NARFL
nuclear prelamin A recognition factor-like
chr4_+_154397975 0.206 TRIM2
tripartite motif containing 2
chr4_+_71713324 0.202 NM_031889
ENAM
enamelin
chr19_+_4742727 0.201 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr11_+_74539679 0.195 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr17_-_37599953 0.187 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr16_-_66528235 0.187 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_179269766 0.181 MR1
major histocompatibility complex, class I-related
chr17_-_59818033 0.176 PECAM1
platelet/endothelial cell adhesion molecule
chr1_+_160002746 0.171 ATF6
activating transcription factor 6
chr19_+_60109319 0.169 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr14_-_106270497 0.168 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr1_+_160002733 0.165 ATF6
activating transcription factor 6
chr9_-_106401514 0.160 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr1_-_155052562 0.151 NM_001161443
SH2D2A
SH2 domain containing 2A
chr15_+_83092525 0.149 ZNF592
zinc finger protein 592
chr4_-_41849333 0.142 BEND4
BEN domain containing 4
chr8_+_7663908 0.138 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr11_-_113082233 0.132 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr11_+_60858611 0.128 DAK
dihydroxyacetone kinase 2 homolog (S. cerevisiae)
chr1_+_111963920 0.126 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr5_+_140605330 0.125 NM_018935
PCDHB15
protocadherin beta 15
chr1_-_149004879 0.117 CTSS
cathepsin S
chr14_-_20563698 0.115 NDRG2
NDRG family member 2
chr13_+_96592051 0.112 MBNL2
muscleblind-like 2 (Drosophila)
chr12_+_21417068 0.109 NM_000415
IAPP
islet amyloid polypeptide
chr13_-_99983945 0.109 NM_033110
A2LD1
AIG2-like domain 1
chr8_+_7656261 0.106 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr2_-_56266408 0.098 LOC100129434
hypothetical LOC100129434
chr19_-_59568483 0.097 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr14_-_105623358 0.094 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_-_46626474 0.093 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr11_+_63060848 0.086 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr14_-_105589467 0.084 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr8_-_7427584 0.084 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr20_-_23679558 0.082 NM_001898
CST1
cystatin SN
chr4_-_69852090 0.081 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr19_+_40322231 0.079 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr22_-_37858871 0.077 CBX7
chromobox homolog 7
chr8_+_7610374 0.076 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr19_+_55164668 0.075 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr4_-_164614335 0.071 NM_032136
TKTL2
transketolase-like 2
chr16_-_11783908 0.069 NM_014153
ZC3H7A
zinc finger CCCH-type containing 7A
chr14_-_20563722 0.069 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr3_+_46423682 0.069 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr3_-_121884091 0.066 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr6_+_38798529 0.065 NM_001371
DNAH8
dynein, axonemal, heavy chain 8
chr3_+_185515108 0.065 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr17_+_35425139 0.063 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr8_+_7633318 0.063 NM_001164450
FAM90A8
family with sequence similarity 90, member A8
chr10_+_102748062 0.063 LZTS2
leucine zipper, putative tumor suppressor 2
chr8_+_7648613 0.061 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr1_-_157950898 0.059 NM_000567
CRP
C-reactive protein, pentraxin-related
chr18_+_53967544 0.059 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr2_-_169455167 0.056 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr19_+_42033564 0.056 ZNF345
zinc finger protein 345
chr15_+_22772545 0.056 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr14_-_105817101 0.055


chr3_-_50583425 0.054 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr3_+_185515543 0.053 NM_182917
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr9_-_116196505 0.052 NM_030767
AKNA
AT-hook transcription factor
chr12_+_49604782 0.051 NM_014033
METTL7A
methyltransferase like 7A
chr6_+_29187565 0.051 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr21_+_30886629 0.050 NM_181605
KRTAP6-3
keratin associated protein 6-3
chr4_-_155531898 0.050 NM_017639
DCHS2
dachsous 2 (Drosophila)
chr1_-_171441234 0.048 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_+_7139945 0.047 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chr1_+_144149794 0.044 NM_006472
TXNIP
thioredoxin interacting protein
chr3_+_160269734 0.043 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr14_+_20226762 0.042 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr8_+_7101835 0.041 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr19_+_53189719 0.040 NM_022142
ELSPBP1
epididymal sperm binding protein 1
chr4_+_166348273 0.039 KLHL2
kelch-like 2, Mayven (Drosophila)
chr1_+_12108542 0.037 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr15_+_83092806 0.037 NM_014630
ZNF592
zinc finger protein 592
chr4_+_8493396 0.035 NM_152544
METTL19
methyltransferase like 19
chr3_-_110517929 0.033 NM_138815
DPPA2
developmental pluripotency associated 2
chr20_-_23617606 0.030 NM_001899
CST4
cystatin S
chr8_+_7618022 0.030 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr1_+_151655623 0.028 NM_176823
S100A7A
S100 calcium binding protein A7A
chr9_+_138966588 0.028 NM_178536
LCN12
lipocalin 12
chr14_-_105657378 0.026 IGHV4-31
immunoglobulin heavy variable 4-31
chr12_+_10054492 0.026 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chr8_+_62363078 0.025 NM_173519
CLVS1
clavesin 1
chr6_-_31007905 0.025 NM_205854
SFTA2
surfactant associated 2
chr7_-_131483925 0.024 PLXNA4
plexin A4
chr8_+_7132323 0.024 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr5_-_95044415 0.024 NM_031952
SPATA9
spermatogenesis associated 9
chr5_+_95008236 0.023 NM_001131066
NM_001131065
NM_173362
RFESD


Rieske (Fe-S) domain containing


chr1_+_226462363 0.022 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr8_+_7124701 0.021 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr2_+_28572441 0.018 NM_001170585
NM_153021
PLB1

phospholipase B1

chr15_+_63701322 0.018 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr3_-_153541468 0.017 NM_001123228
TMEM14E
transmembrane protein 14E
chr5_-_149446366 0.017 CSF1R
colony stimulating factor 1 receptor
chr9_-_132759045 0.017 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr18_+_12981329 0.016 NM_032142
CEP192
centrosomal protein 192kDa
chr1_+_13588674 0.016 NM_001099851
PRAMEF17
PRAME family member 17
chr5_-_149446287 0.016 CSF1R
colony stimulating factor 1 receptor
chrX_-_6463158 0.014 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr2_+_230989150 0.012 SP100
SP100 nuclear antigen
chrX_-_8099307 0.011 NM_016378
VCX2
variable charge, X-linked 2
chr5_-_149446303 0.011 CSF1R
colony stimulating factor 1 receptor
chr19_+_6981593 0.010 NM_001136507
MBD3L5
methyl-CpG-binding domain protein 3-like 5-like
chr12_-_102874980 0.009 NM_001135570
C12orf73
chromosome 12 open reading frame 73
chr9_-_124370576 0.007 NM_001004454
OR1L8
olfactory receptor, family 1, subfamily L, member 8
chr11_+_55362802 0.007 NM_001005496
OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr15_+_57696200 0.006 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_-_149304475 0.006 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chrX_+_8392870 0.006 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr1_-_104040308 0.003 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr1_-_144426918 0.003 NM_007053
CD160
CD160 molecule
chr1_+_103999824 0.002 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr20_+_86121 0.002 NM_139074
DEFB127
defensin, beta 127
chr18_+_30652223 0.002 NM_001198942
NM_001198944
NM_032980
NM_032981
DTNA



dystrobrevin, alpha



chr10_-_48426868 0.001 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr3_-_191650291 0.001 NM_207316
TMEM207
transmembrane protein 207
chr12_+_124115877 0.001 NM_023928
AACS
acetoacetyl-CoA synthetase
chr20_-_36191623 0.001 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chrX_+_37735013 0.000 NM_012274
CXorf27
chromosome X open reading frame 27

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.35 2.43e-03 GO:0006955 immune response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
22.41 2.23e-06 GO:0003823 antigen binding