Motif ID: CUX2.p2

Z-value: 0.919


Transcription factors associated with CUX2.p2:

Gene SymbolEntrez IDGene Name
CUX2 23316 cut-like homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CUX2chr12_+_109956210-0.039.2e-01Click!


Activity profile for motif CUX2.p2.

activity profile for motif CUX2.p2


Sorted Z-values histogram for motif CUX2.p2

Sorted Z-values for motif CUX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_45654292 3.317 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_45654296 2.614 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_196874839 2.499 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_196874759 2.361 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_196874867 2.326 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_-_100077072 1.965 NM_003227
TFR2
transferrin receptor 2
chr12_+_130004404 1.714 NM_198827
GPR133
G protein-coupled receptor 133
chr7_-_23476497 1.197 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr1_+_50344550 1.191 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_+_169634330 1.180 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr13_-_45654327 1.174 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_88946767 1.120


chr19_-_51979838 0.846 NM_001145145
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr17_-_44042924 0.819 HOXB7
homeobox B7
chr1_+_57093030 0.756 NM_000562
C8A
complement component 8, alpha polypeptide
chr1_-_51660328 0.737 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr14_-_23090606 0.720 NM_033400
ZFHX2
zinc finger homeobox 2
chr1_-_144779601 0.713 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chrX_-_63532057 0.708 NM_017677
MTMR8
myotubularin related protein 8
chr16_+_11966464 0.694 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_-_146076704 0.636 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr6_-_68655708 0.576


chr12_-_53661888 0.573 NM_001098815
KIAA0748
KIAA0748
chr10_+_69539255 0.562 NM_032578
MYPN
myopalladin
chr14_+_87560646 0.543 LOC283587
hypothetical protein LOC283587
chr11_+_22646229 0.524 NM_177553
GAS2
growth arrest-specific 2
chr7_-_92615593 0.518 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr7_+_80069439 0.510 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr3_+_35696119 0.458 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr12_+_109956210 0.416 NM_015267
CUX2
cut-like homeobox 2
chr6_-_154719560 0.405 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr20_-_33705244 0.399 NM_003915
CPNE1
copine I
chr10_+_68355797 0.390 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr9_+_109131814 0.388 RAD23B
RAD23 homolog B (S. cerevisiae)
chr17_-_44043278 0.383 HOXB7
homeobox B7
chrX_+_123307812 0.382 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr12_+_6424293 0.373 NM_001242
CD27
CD27 molecule
chr9_+_95886625 0.372 PTPDC1
protein tyrosine phosphatase domain containing 1
chr5_+_40877053 0.336 NM_032587
CARD6
caspase recruitment domain family, member 6
chrX_-_11194015 0.336 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr7_-_112515035 0.316 GPR85
G protein-coupled receptor 85
chr7_-_112515068 0.311 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr3_-_114176401 0.307 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr11_-_58368555 0.305 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr2_+_132196533 0.304 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr8_-_86477585 0.304 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr1_+_204797079 0.300 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr1_+_144374513 0.294 RNF115
ring finger protein 115
chr17_-_44043361 0.291 NM_004502
HOXB7
homeobox B7
chr12_-_52939636 0.277 NM_001127321
CBX5
chromobox homolog 5
chr1_+_117098579 0.277 NM_001767
CD2
CD2 molecule
chr12_+_14429499 0.269 ATF7IP
activating transcription factor 7 interacting protein
chr6_-_32268615 0.265 GPSM3
G-protein signaling modulator 3
chr9_+_95886558 0.257 NM_152422
PTPDC1
protein tyrosine phosphatase domain containing 1
chr5_-_43448174 0.249 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr8_-_18585721 0.249 PSD3
pleckstrin and Sec7 domain containing 3
chr11_+_59902530 0.237 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr4_+_71806538 0.236 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr7_-_36730525 0.236 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr12_-_11313907 0.234 NM_006249
PRB3
proline-rich protein BstNI subfamily 3
chr7_+_113853790 0.232 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr4_+_77214886 0.227 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr17_+_65009986 0.219 MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_72868598 0.217 NM_000583
GC
group-specific component (vitamin D binding protein)
chr1_+_160002733 0.214 ATF6
activating transcription factor 6
chr3_+_101720753 0.213 TMEM45A
transmembrane protein 45A
chr3_-_25658829 0.213 TOP2B
topoisomerase (DNA) II beta 180kDa
chr1_+_357502 0.206 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr14_-_20098929 0.198 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr15_-_64582049 0.198 RPL4
ribosomal protein L4
chr6_-_27907283 0.189 NM_003541
HIST1H4A
HIST1H4F
HIST1H4K
HIST1H4J
histone cluster 1, H4a
histone cluster 1, H4f
histone cluster 1, H4k
histone cluster 1, H4j
chr8_-_107023 0.189 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr5_+_180726874 0.189 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr2_-_171999473 0.188 NM_024770
METTL8
methyltransferase like 8
chr14_-_19252330 0.181 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr13_-_35327798 0.173 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr8_-_120720200 0.173 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr14_-_19867372 0.171 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr1_+_160002693 0.170 NM_007348
ATF6
activating transcription factor 6
chr13_-_40454360 0.168 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_+_33306652 0.155 HIPK3
homeodomain interacting protein kinase 3
chr1_+_160002746 0.154 ATF6
activating transcription factor 6
chr1_-_157950898 0.154 NM_000567
CRP
C-reactive protein, pentraxin-related
chr9_+_124173049 0.154 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr8_-_82557956 0.153 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr4_+_71330797 0.150 NM_001145006
MUC7
mucin 7, secreted
chr1_-_611896 0.146 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr11_+_59038961 0.146 NM_001004711
OR4D9
olfactory receptor, family 4, subfamily D, member 9
chr7_+_99263571 0.145 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr11_+_59902598 0.143 MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr16_+_68156497 0.135 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NFAT5




nuclear factor of activated T-cells 5, tonicity-responsive




chr10_-_69125932 0.134 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr10_-_42183441 0.128 LOC283027
hypothetical protein LOC283027
chr8_+_17866373 0.124 PCM1
pericentriolar material 1
chr15_-_73705773 0.124 NM_001042588
SNUPN
snurportin 1
chr6_+_32817140 0.117 NM_020056
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr7_+_156677777 0.117


chr6_+_155579788 0.113 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_-_150070849 0.113 NM_005060
RORC
RAR-related orphan receptor C
chr10_-_98326435 0.110 TM9SF3
transmembrane 9 superfamily member 3
chr17_-_77469280 0.109 SIRT7
sirtuin 7
chr3_+_135996734 0.106 NM_004441
EPHB1
EPH receptor B1
chr9_-_114814286 0.105 NM_001101338
ZNF883
zinc finger protein 883
chr17_-_77469316 0.104 SIRT7
sirtuin 7
chr4_+_15038726 0.102 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr21_+_29322100 0.101 USP16
ubiquitin specific peptidase 16
chr3_-_150422474 0.098 NM_000096
CP
ceruloplasmin (ferroxidase)
chr1_+_51340487 0.098 NM_001136508
C1orf185
chromosome 1 open reading frame 185
chr12_-_116890410 0.097 NM_173598
KSR2
kinase suppressor of ras 2
chrX_+_30169977 0.094 NM_002367
MAGEB4
melanoma antigen family B, 4
chr7_+_143646150 0.093 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr13_-_83354425 0.084 SLITRK1
SLIT and NTRK-like family, member 1
chr7_+_116182676 0.084


chr4_-_68766392 0.082 NM_001129907
TMPRSS11BNL
TMPRSS11B N terminal-like
chr4_-_47678187 0.080 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr10_+_63331018 0.079 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chrX_+_134482212 0.079 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr18_+_59767567 0.078 NM_001123366
HMSD
histocompatibility (minor) serpin domain containing
chr1_+_246635918 0.078 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr22_-_25291268 0.076 NM_001008566
TPST2
tyrosylprotein sulfotransferase 2
chr22_-_38619739 0.073 NM_152512
ENTHD1
ENTH domain containing 1
chr3_+_159310631 0.072 RSRC1
arginine/serine-rich coiled-coil 1
chr7_-_143560850 0.071 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr17_+_36599664 0.068 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr7_+_116238309 0.064 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr14_-_23117268 0.060 JPH4
junctophilin 4
chr12_+_54011750 0.060 NM_054104
OR6C3
olfactory receptor, family 6, subfamily C, member 3
chr15_+_56511466 0.059 NM_000236
LIPC
lipase, hepatic
chrX_+_30158473 0.059 NM_002365
MAGEB3
melanoma antigen family B, 3
chr12_+_124377114 0.058 NM_052907
TMEM132B
transmembrane protein 132B
chr11_-_30562324 0.057 MPPED2
metallophosphoesterase domain containing 2
chr6_-_10939095 0.057 NM_005906
MAK
male germ cell-associated kinase
chrX_-_135166306 0.056 NM_001173516
MAP7D3
MAP7 domain containing 3
chr16_-_73708118 0.055 LDHD
lactate dehydrogenase D
chr14_+_38653177 0.054 NM_001009182
NM_001009183
NM_003616
SIP1


survival of motor neuron protein interacting protein 1


chr15_-_86890796 0.052 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr14_+_55148488 0.051 KTN1
kinectin 1 (kinesin receptor)
chr8_-_17797127 0.051 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr11_+_60223622 0.049 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr11_+_94398069 0.049 NM_001161630
KDM4DL
lysine (K)-specific demethylase 4D-like
chr11_+_116580892 0.045 TAGLN
transgelin
chr13_-_83354474 0.044 NM_052910
SLITRK1
SLIT and NTRK-like family, member 1
chr15_+_36014748 0.044 NM_152453
TMCO5A
transmembrane and coiled-coil domains 5A
chr3_+_173043832 0.044 NM_001164436
TMEM212
transmembrane protein 212
chr6_-_26216299 0.043 NM_005323
HIST1H1T
histone cluster 1, H1t
chr12_+_6703549 0.043 COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr5_-_147142249 0.042 JAKMIP2
janus kinase and microtubule interacting protein 2
chr16_+_29971955 0.042 ALDOA
aldolase A, fructose-bisphosphate
chr3_-_127760447 0.041 NM_152533
C3orf22
chromosome 3 open reading frame 22
chr6_+_31081707 0.039 NM_001198815
PBMUCL1
panbronchiolitis related mucin-like 1
chr1_-_245942679 0.038 NM_001005286
OR6F1
olfactory receptor, family 6, subfamily F, member 1
chr14_+_28311740 0.038 C14orf23
chromosome 14 open reading frame 23
chr4_-_2200755 0.037 NM_181808
POLN
polymerase (DNA directed) nu
chr2_+_204509698 0.037 NM_012092
ICOS
inducible T-cell co-stimulator
chr1_+_165330710 0.037 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr8_+_11225904 0.036 NM_054028
AMAC1L2
acyl-malonyl condensing enzyme 1-like 2
chr12_+_102859354 0.034 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr9_-_139262009 0.033 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr3_-_42427026 0.032 NM_144634
LYZL4
lysozyme-like 4
chr4_+_41395493 0.032 LIMCH1
LIM and calponin homology domains 1
chr4_-_82345224 0.030 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chr1_-_150805852 0.030 NM_178435
LCE3E
late cornified envelope 3E
chr6_+_27400518 0.028 NM_032030
FKSG83
FKSG83
chr11_-_74478405 0.027 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr11_-_57964221 0.026 NM_001004733
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr16_+_29971971 0.026 NM_000034
ALDOA
aldolase A, fructose-bisphosphate
chr1_+_147006065 0.026 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr17_-_36209672 0.026 NM_181535
KRT28
keratin 28
chr3_-_187744808 0.026 NM_017541
CRYGS
crystallin, gamma S
chr8_+_67505091 0.025 RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr5_+_140227951 0.025 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr10_-_99383841 0.024 NM_001098831
MORN4
MORN repeat containing 4
chr3_+_46894239 0.022 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr11_+_55407348 0.022 NM_032681
SPRYD5
SPRY domain containing 5
chr12_+_6703525 0.022 COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr11_+_60016826 0.021 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr19_+_49337548 0.021 NM_001144824
NM_006630
ZNF234

zinc finger protein 234

chr11_-_56166490 0.021 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr12_-_52939584 0.021 NM_001127322
CBX5
chromobox homolog 5
chr18_-_29882555 0.019 NM_001198549
NOL4
nucleolar protein 4
chr13_+_50813168 0.018 NM_001101320
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr11_-_34489693 0.018 NM_198381
ELF5
E74-like factor 5 (ets domain transcription factor)
chr19_+_49337568 0.016 ZNF234
zinc finger protein 234
chr10_+_104580420 0.015


chr12_-_11354620 0.015 NM_002723
PRB4
proline-rich protein BstNI subfamily 4
chr18_+_57308754 0.015 NM_031891
CDH20
cadherin 20, type 2
chr1_+_144595224 0.014 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr6_+_159229606 0.013 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chrX_-_118610880 0.013 NM_001173488
NKRF
NFKB repressing factor
chr7_-_18033970 0.012 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr4_-_70861301 0.012 NM_001891
CSN2
casein beta
chr12_-_21980894 0.009 NM_005691
NM_020297
NM_020298
ABCC9


ATP-binding cassette, sub-family C (CFTR/MRP), member 9


chr17_+_53670785 0.008 NM_001160102
NM_006151
LPO

lactoperoxidase

chr3_+_51837608 0.008 NM_001085479
IQCF3
IQ motif containing F3
chr18_-_29273979 0.008 NM_001105528
C18orf34
chromosome 18 open reading frame 34
chr5_+_60969392 0.007 NM_173667
FLJ37543
hypothetical protein FLJ37543
chr10_-_98280299 0.006 TM9SF3
transmembrane 9 superfamily member 3
chr5_-_58918031 0.006 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_124172644 0.006 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_61098867 0.005 NM_144709
PUS10
pseudouridylate synthase 10

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.04 9.06e-03 GO:0004872 receptor activity