Motif ID: TFDP1.p2

Z-value: 2.376


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFDP1chr13_+_113287048-0.361.8e-01Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_160964574 4.196 SCHIP1
schwannomin interacting protein 1
chr19_+_16296734 3.510 KLF2
Kruppel-like factor 2 (lung)
chr15_-_81667169 3.344 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr19_-_45888259 3.207 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr13_-_109236897 2.941 NM_003749
IRS2
insulin receptor substrate 2
chr9_-_109291575 2.930 KLF4
Kruppel-like factor 4 (gut)
chr4_-_122063118 2.874 NM_018699
PRDM5
PR domain containing 5
chr10_-_126839546 2.746 NM_001083914
CTBP2
C-terminal binding protein 2
chr19_+_16296632 2.723 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr9_+_81377419 2.577 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_-_36531958 2.577 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr18_+_12298242 2.487 NM_032525
TUBB6
tubulin, beta 6
chr9_-_16860719 2.459 NM_017637
BNC2
basonuclin 2
chr2_-_144991386 2.385 ZEB2
zinc finger E-box binding homeobox 2
chr10_-_126839056 2.352 NM_001329
CTBP2
C-terminal binding protein 2
chr4_-_57671273 2.346 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr7_-_50828159 2.309 GRB10
growth factor receptor-bound protein 10
chr20_-_55718351 2.269 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr17_-_40263124 2.254 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr9_-_16860664 2.253 BNC2
basonuclin 2
chr15_-_27901628 2.236 TJP1
tight junction protein 1 (zona occludens 1)
chr9_-_13269562 2.225 MPDZ
multiple PDZ domain protein
chr16_+_85158357 2.093 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr15_-_80125514 2.084 MEX3B
mex-3 homolog B (C. elegans)
chr10_+_124211353 2.078 HTRA1
HtrA serine peptidase 1
chr9_-_109291866 2.071 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr3_-_71196696 2.025 FOXP1
forkhead box P1
chr18_-_21184824 2.024


chr18_-_44189625 2.007 ZBTB7C
zinc finger and BTB domain containing 7C
chr4_-_57671112 1.986 IGFBP7
insulin-like growth factor binding protein 7
chr8_+_38763911 1.974 TACC1
transforming, acidic coiled-coil containing protein 1
chr10_-_126839000 1.970 CTBP2
C-terminal binding protein 2
chr4_+_89147821 1.952 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr13_-_105985313 1.947 NM_004093
EFNB2
ephrin-B2
chr15_+_81567327 1.946 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr20_+_8997791 1.935 PLCB4
phospholipase C, beta 4
chr4_-_57671307 1.933 IGFBP7
insulin-like growth factor binding protein 7
chr1_-_226202210 1.926 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr20_+_59260847 1.889 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr15_-_80125403 1.875 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr2_-_160972606 1.861 RBMS1
RNA binding motif, single stranded interacting protein 1
chr15_-_27901828 1.848 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr15_-_46724360 1.839 FBN1
fibrillin 1
chr5_+_92946348 1.834 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr3_+_137167153 1.830 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr1_-_223907283 1.790 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr10_+_83625049 1.789 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr15_-_42274760 1.785 FRMD5
FERM domain containing 5
chr9_-_93225961 1.784 NM_005384
NFIL3
nuclear factor, interleukin 3 regulated
chr6_-_91063181 1.776 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr2_+_159533329 1.770 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr5_+_10617431 1.744 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr5_-_16989371 1.743 NM_012334
MYO10
myosin X
chr20_+_8997660 1.725 NM_001172646
PLCB4
phospholipase C, beta 4
chr9_-_79835970 1.715 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr10_+_122206455 1.700 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr4_+_145786622 1.685 NM_022475
HHIP
hedgehog interacting protein
chr2_+_28469864 1.684 FOSL2
FOS-like antigen 2
chr3_+_112273352 1.680 PVRL3
poliovirus receptor-related 3
chr16_-_53520208 1.676 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr3_+_137167296 1.675 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr7_+_116099648 1.673 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr22_-_34754343 1.673 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr1_+_156229934 1.652 KIRREL
kin of IRRE like (Drosophila)
chr15_-_81667773 1.649 HDGFRP3
hepatoma-derived growth factor, related protein 3
chr15_-_42274529 1.647 NM_032892
FRMD5
FERM domain containing 5
chr15_+_66658626 1.646 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr3_-_64648370 1.645 NM_182920
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr10_+_124210980 1.625 NM_002775
HTRA1
HtrA serine peptidase 1
chr7_-_42243318 1.622 GLI3
GLI family zinc finger 3
chr11_-_86060812 1.614 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr5_-_178705036 1.599 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr5_+_60663842 1.589 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr18_+_12298189 1.582 TUBB6
tubulin, beta 6
chr2_+_241023703 1.579 NM_002081
GPC1
glypican 1
chr19_+_39664706 1.567 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr9_+_136673534 1.559 COL5A1
collagen, type V, alpha 1
chr3_+_112273464 1.552 NM_015480
PVRL3
poliovirus receptor-related 3
chr18_+_12298236 1.546 TUBB6
tubulin, beta 6
chr17_-_60088637 1.543 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr5_-_178704934 1.536 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr2_-_235070431 1.532 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr1_-_68071635 1.512 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr9_-_112840064 1.512 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr17_+_52026058 1.501 NM_005450
NOG
noggin
chr7_-_81910740 1.493 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr12_-_87498225 1.493 NM_000899
NM_003994
KITLG

KIT ligand

chr1_+_64012154 1.493 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr1_-_95165089 1.484 NM_001839
CNN3
calponin 3, acidic
chr9_+_81377289 1.478 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_-_93184629 1.468 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr16_+_12902955 1.459 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr6_-_112301123 1.452 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr22_+_18081968 1.429 NM_002688
SEPT5
septin 5
chr2_+_206255597 1.427 NRP2
neuropilin 2
chr11_+_35596310 1.425 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr2_-_1727292 1.422 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr5_+_170221584 1.418 NM_022897
RANBP17
RAN binding protein 17
chr2_+_241023880 1.408


chr2_+_29191711 1.407 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr16_+_53522611 1.398 NM_005853
IRX5
iroquois homeobox 5
chr8_+_38763878 1.384 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr9_-_109291130 1.382 KLF4
Kruppel-like factor 4 (gut)
chr6_-_85530617 1.382 NM_001080508
TBX18
T-box 18
chr7_-_42243142 1.376 NM_000168
GLI3
GLI family zinc finger 3
chr10_-_131652007 1.371 NM_001005463
EBF3
early B-cell factor 3
chr2_-_1727247 1.371 PXDN
peroxidasin homolog (Drosophila)
chr17_+_78630793 1.370 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr5_+_34692352 1.355 NM_001145520
RAI14
retinoic acid induced 14
chrX_-_34585287 1.352 NM_031442
TMEM47
transmembrane protein 47
chr9_+_138680064 1.327 EGFL7
EGF-like-domain, multiple 7
chr16_-_62573 1.327 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr12_+_50271283 1.325 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr2_+_206255376 1.320 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr19_-_6061491 1.314 RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr3_-_187025438 1.309 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr9_+_90796169 1.297 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chrX_-_135161185 1.296 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr2_-_175255717 1.296 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_23461802 1.295 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr11_+_12355600 1.290 NM_018222
PARVA
parvin, alpha
chr2_+_85213884 1.287 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr7_-_50828608 1.274 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr1_+_182622987 1.270 C1orf21
chromosome 1 open reading frame 21
chr2_-_144991556 1.266 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_48387233 1.262


chr1_+_170077234 1.262 NM_001136127
NM_015569
DNM3

dynamin 3

chr11_-_44928803 1.261 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr5_-_16989290 1.252 MYO10
myosin X
chr3_-_129024665 1.250 NM_001003794
MGLL
monoglyceride lipase
chr15_-_43602293 1.249 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr8_+_60194328 1.235


chr7_-_27149750 1.230 NM_019102
HOXA5
homeobox A5
chr10_+_23768203 1.227 NM_001145373
OTUD1
OTU domain containing 1
chr5_+_34692124 1.214 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr1_+_182622850 1.212 C1orf21
chromosome 1 open reading frame 21
chr12_+_8741746 1.211 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr17_-_15106525 1.205 PMP22
peripheral myelin protein 22
chr20_+_55718619 1.204


chr9_+_115678365 1.200 NM_133374
ZNF618
zinc finger protein 618
chrX_+_106956115 1.198 MID2
midline 2
chr3_+_11171213 1.195 NM_001098212
HRH1
histamine receptor H1
chr9_+_136673464 1.195 NM_000093
COL5A1
collagen, type V, alpha 1
chr12_-_41269679 1.191 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr3_-_151171190 1.188 NM_002628
NM_053024
PFN2

profilin 2

chr7_-_28186671 1.188 JAZF1
JAZF zinc finger 1
chr1_+_208472817 1.184 NM_019605
SERTAD4
SERTA domain containing 4
chrX_+_149282097 1.182 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr6_+_1556543 1.173 FOXC1
forkhead box C1
chr3_-_187025501 1.164 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr19_-_54557450 1.160 NM_003598
TEAD2
TEA domain family member 2
chr18_-_21186107 1.157 NM_015461
ZNF521
zinc finger protein 521
chr11_+_19691397 1.155 NM_145117
NM_182964
NAV2

neuron navigator 2

chr17_-_60088773 1.153 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr15_+_94674849 1.150 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_-_13035102 1.149 NM_006094
DLC1
deleted in liver cancer 1
chr10_+_129595289 1.133 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_+_123862430 1.127 TACC2
transforming, acidic coiled-coil containing protein 2
chr12_-_94708477 1.126 NTN4
netrin 4
chr9_+_100907292 1.126


chr5_+_172000793 1.125 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr9_+_131974506 1.124 NM_014286
NCS1
neuronal calcium sensor 1
chr2_+_28469850 1.114 FOSL2
FOS-like antigen 2
chr6_+_45497796 1.110 NM_004348
RUNX2
runt-related transcription factor 2
chr9_+_100907222 1.109 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr4_-_174326880 1.109


chr5_+_17270781 1.109 BASP1
brain abundant, membrane attached signal protein 1
chr14_-_29466562 1.109 NM_002742
PRKD1
protein kinase D1
chr1_+_182622809 1.108 C1orf21
chromosome 1 open reading frame 21
chr22_+_49459935 1.106 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr9_-_25668230 1.104 TUSC1
tumor suppressor candidate 1
chr1_+_182622751 1.103 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr12_-_105056577 1.103 NUAK1
NUAK family, SNF1-like kinase, 1
chr10_+_112247614 1.100 NM_004419
DUSP5
dual specificity phosphatase 5
chr20_+_41976831 1.098 NM_001098797
TOX2
TOX high mobility group box family member 2
chr2_+_36436316 1.092 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr4_-_99798563 1.091 NM_005723
TSPAN5
tetraspanin 5
chr19_+_627346 1.090 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr7_-_81910956 1.089 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr9_+_100907213 1.080 TGFBR1
transforming growth factor, beta receptor 1
chr2_-_45090025 1.073 NM_016932
SIX2
SIX homeobox 2
chr21_+_41461924 1.071 BACE2
beta-site APP-cleaving enzyme 2
chr9_-_72218098 1.066 KLF9
Kruppel-like factor 9
chr5_+_170221441 1.065 RANBP17
RAN binding protein 17
chr9_-_14304036 1.062 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr7_-_525556 1.061 PDGFA
platelet-derived growth factor alpha polypeptide
chr3_-_180651874 1.059 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr2_-_1727220 1.058 PXDN
peroxidasin homolog (Drosophila)
chr11_-_86061003 1.057 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr9_+_100907189 1.056 TGFBR1
transforming growth factor, beta receptor 1
chr1_+_156229686 1.054 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr9_+_123501186 1.053 DAB2IP
DAB2 interacting protein
chr9_-_93225780 1.053 NFIL3
nuclear factor, interleukin 3 regulated
chr3_-_189354510 1.046 LOC339929
hypothetical LOC339929
chr10_-_131652364 1.037 EBF3
early B-cell factor 3
chr7_+_128257698 1.033 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr22_-_35113797 1.033 MYH9
myosin, heavy chain 9, non-muscle
chr7_-_525336 1.032 PDGFA
platelet-derived growth factor alpha polypeptide
chr7_+_33911636 1.032 NM_133468
BMPER
BMP binding endothelial regulator
chr3_-_64648703 1.031 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 1.11e-37 GO:0009987 cellular process
1.18 1.95e-29 GO:0044237 cellular metabolic process
1.24 2.09e-29 GO:0044260 cellular macromolecule metabolic process
1.15 1.45e-22 GO:0008152 metabolic process
1.19 2.71e-22 GO:0043170 macromolecule metabolic process
1.15 1.78e-20 GO:0044238 primary metabolic process
1.14 4.05e-20 GO:0050794 regulation of cellular process
1.27 9.93e-20 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 1.35e-16 GO:0050789 regulation of biological process
1.25 1.91e-16 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 2.76e-16 GO:0034641 cellular nitrogen compound metabolic process
1.27 4.20e-16 GO:0090304 nucleic acid metabolic process
1.25 5.54e-16 GO:0071842 cellular component organization at cellular level
1.22 6.97e-16 GO:0006807 nitrogen compound metabolic process
1.11 7.67e-15 GO:0065007 biological regulation
1.21 8.71e-15 GO:0016043 cellular component organization
1.20 1.50e-14 GO:0071840 cellular component organization or biogenesis
1.20 7.04e-14 GO:0060255 regulation of macromolecule metabolic process
1.41 3.91e-13 GO:0022008 neurogenesis
1.31 9.45e-13 GO:0007399 nervous system development
1.19 1.09e-12 GO:0031323 regulation of cellular metabolic process
1.18 4.18e-12 GO:0080090 regulation of primary metabolic process
1.40 4.61e-12 GO:0048699 generation of neurons
1.27 8.49e-12 GO:0006464 protein modification process
1.27 1.52e-11 GO:0016070 RNA metabolic process
1.22 2.55e-11 GO:0044267 cellular protein metabolic process
1.17 3.74e-11 GO:0019222 regulation of metabolic process
1.22 4.51e-11 GO:0048522 positive regulation of cellular process
1.28 6.09e-11 GO:0023051 regulation of signaling
1.29 8.95e-11 GO:0009653 anatomical structure morphogenesis
1.26 9.37e-11 GO:0010467 gene expression
1.29 1.16e-10 GO:0009966 regulation of signal transduction
1.25 1.24e-10 GO:0043412 macromolecule modification
1.42 3.34e-10 GO:0030182 neuron differentiation
1.26 5.71e-10 GO:0034645 cellular macromolecule biosynthetic process
1.20 6.00e-10 GO:0048518 positive regulation of biological process
1.50 6.09e-10 GO:0031175 neuron projection development
1.26 1.20e-09 GO:0009059 macromolecule biosynthetic process
1.16 1.77e-09 GO:0032502 developmental process
1.20 3.63e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.43 4.66e-09 GO:0000902 cell morphogenesis
1.47 5.36e-09 GO:0000904 cell morphogenesis involved in differentiation
1.20 1.10e-08 GO:0044249 cellular biosynthetic process
1.43 1.16e-08 GO:0048666 neuron development
1.19 1.49e-08 GO:0010468 regulation of gene expression
1.18 1.54e-08 GO:0048731 system development
1.34 2.48e-08 GO:0006351 transcription, DNA-dependent
1.40 3.29e-08 GO:0032989 cellular component morphogenesis
1.16 3.93e-08 GO:0007275 multicellular organismal development
1.17 4.84e-08 GO:0048856 anatomical structure development
1.18 4.86e-08 GO:0009889 regulation of biosynthetic process
1.18 5.12e-08 GO:0031326 regulation of cellular biosynthetic process
1.19 5.65e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.48 5.94e-08 GO:0048812 neuron projection morphogenesis
1.40 6.78e-08 GO:0030030 cell projection organization
1.20 8.20e-08 GO:0051252 regulation of RNA metabolic process
1.19 9.16e-08 GO:0009058 biosynthetic process
1.18 1.29e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 1.44e-07 GO:0032774 RNA biosynthetic process
1.32 1.54e-07 GO:0048468 cell development
1.47 2.50e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.47 2.86e-07 GO:0007409 axonogenesis
1.26 3.39e-07 GO:0035556 intracellular signal transduction
1.30 3.58e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.20 5.29e-07 GO:0048523 negative regulation of cellular process
1.33 5.71e-07 GO:0051128 regulation of cellular component organization
1.17 6.71e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.16 6.87e-07 GO:0019538 protein metabolic process
1.32 1.20e-06 GO:0033554 cellular response to stress
1.22 2.04e-06 GO:0006996 organelle organization
1.41 2.14e-06 GO:0032990 cell part morphogenesis
1.18 2.37e-06 GO:0048519 negative regulation of biological process
1.41 2.70e-06 GO:0048858 cell projection morphogenesis
1.19 2.90e-06 GO:0006355 regulation of transcription, DNA-dependent
1.12 7.33e-06 GO:0051716 cellular response to stimulus
1.13 7.75e-06 GO:0023052 signaling
1.18 1.72e-05 GO:0030154 cell differentiation
1.18 2.34e-05 GO:0048869 cellular developmental process
1.27 2.35e-05 GO:0032268 regulation of cellular protein metabolic process
1.47 2.68e-05 GO:0007411 axon guidance
1.13 3.76e-05 GO:0007165 signal transduction
1.25 7.72e-05 GO:0051246 regulation of protein metabolic process
1.46 1.57e-04 GO:0060284 regulation of cell development
1.22 1.81e-04 GO:0009893 positive regulation of metabolic process
1.25 2.18e-04 GO:0006793 phosphorus metabolic process
1.25 2.18e-04 GO:0006796 phosphate metabolic process
1.30 2.40e-04 GO:0019220 regulation of phosphate metabolic process
1.30 2.40e-04 GO:0051174 regulation of phosphorus metabolic process
1.24 2.40e-04 GO:0008104 protein localization
1.23 3.50e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.30 3.85e-04 GO:0042325 regulation of phosphorylation
1.39 5.15e-04 GO:0009968 negative regulation of signal transduction
1.23 6.03e-04 GO:0010646 regulation of cell communication
1.22 6.13e-04 GO:0031325 positive regulation of cellular metabolic process
1.76 6.99e-04 GO:0010720 positive regulation of cell development
1.31 7.31e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.28 7.51e-04 GO:0012501 programmed cell death
1.26 9.62e-04 GO:0045184 establishment of protein localization
1.29 1.02e-03 GO:0009890 negative regulation of biosynthetic process
1.30 1.03e-03 GO:0006396 RNA processing
1.35 1.04e-03 GO:0072358 cardiovascular system development
1.35 1.04e-03 GO:0072359 circulatory system development
1.30 1.09e-03 GO:0001932 regulation of protein phosphorylation
1.33 1.24e-03 GO:0006974 response to DNA damage stimulus
1.29 1.56e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.29 1.57e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.25 1.72e-03 GO:0008219 cell death
1.29 1.86e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.28 1.89e-03 GO:0006915 apoptosis
1.25 2.09e-03 GO:0016265 death
1.48 2.35e-03 GO:0001558 regulation of cell growth
1.23 2.44e-03 GO:0032879 regulation of localization
1.23 2.66e-03 GO:0007049 cell cycle
1.44 2.81e-03 GO:0032446 protein modification by small protein conjugation
1.32 3.41e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.35 3.49e-03 GO:0023057 negative regulation of signaling
1.27 3.51e-03 GO:0006468 protein phosphorylation
1.21 4.04e-03 GO:0044248 cellular catabolic process
1.34 4.27e-03 GO:0010648 negative regulation of cell communication
1.39 4.31e-03 GO:0006281 DNA repair
1.32 4.47e-03 GO:0043549 regulation of kinase activity
1.25 4.50e-03 GO:0046907 intracellular transport
1.29 4.56e-03 GO:0010629 negative regulation of gene expression
1.28 5.07e-03 GO:0051726 regulation of cell cycle
1.41 5.10e-03 GO:0008380 RNA splicing
1.20 5.15e-03 GO:0051641 cellular localization
1.31 5.17e-03 GO:0051253 negative regulation of RNA metabolic process
1.31 5.31e-03 GO:0016071 mRNA metabolic process
1.19 5.99e-03 GO:0033036 macromolecule localization
1.39 6.04e-03 GO:0070647 protein modification by small protein conjugation or removal
1.29 6.20e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 6.29e-03 GO:0048583 regulation of response to stimulus
1.25 6.36e-03 GO:0031399 regulation of protein modification process
1.27 6.60e-03 GO:0045595 regulation of cell differentiation
1.50 6.96e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.50 6.96e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.47 7.05e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.49 7.46e-03 GO:0000375 RNA splicing, via transesterification reactions
1.43 7.95e-03 GO:0016567 protein ubiquitination
1.31 8.07e-03 GO:0007417 central nervous system development
1.31 8.07e-03 GO:0051338 regulation of transferase activity
1.29 8.09e-03 GO:0006259 DNA metabolic process
1.24 8.43e-03 GO:0015031 protein transport
1.11 8.57e-03 GO:0051179 localization
1.35 9.00e-03 GO:0006397 mRNA processing
1.23 9.32e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.32 1.16e-02 GO:0045859 regulation of protein kinase activity
1.61 1.40e-02 GO:0033673 negative regulation of kinase activity
1.59 1.47e-02 GO:0051348 negative regulation of transferase activity
1.26 1.60e-02 GO:0051254 positive regulation of RNA metabolic process
1.40 1.61e-02 GO:0001944 vasculature development
1.60 1.84e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.27 1.93e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.62 1.94e-02 GO:0006469 negative regulation of protein kinase activity
1.24 2.03e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.24 2.10e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 2.31e-02 GO:0050767 regulation of neurogenesis
1.74 2.60e-02 GO:0050769 positive regulation of neurogenesis
1.59 2.66e-02 GO:0022604 regulation of cell morphogenesis
1.25 2.66e-02 GO:0010628 positive regulation of gene expression
1.29 2.96e-02 GO:0034613 cellular protein localization
1.39 3.62e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.93 3.64e-02 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1.22 4.16e-02 GO:0009891 positive regulation of biosynthetic process
1.26 4.18e-02 GO:0051276 chromosome organization
1.22 4.37e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.28 4.72e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.22 4.76e-02 GO:0016310 phosphorylation
1.28 4.87e-02 GO:0070727 cellular macromolecule localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 2.14e-61 GO:0044424 intracellular part
1.13 1.31e-59 GO:0005622 intracellular
1.15 1.57e-41 GO:0043227 membrane-bounded organelle
1.15 2.42e-41 GO:0043231 intracellular membrane-bounded organelle
1.14 2.75e-40 GO:0043226 organelle
1.14 1.44e-39 GO:0043229 intracellular organelle
1.14 4.00e-32 GO:0005737 cytoplasm
1.20 4.14e-32 GO:0005634 nucleus
1.05 7.86e-22 GO:0005623 cell
1.05 1.12e-21 GO:0044464 cell part
1.15 1.98e-20 GO:0044444 cytoplasmic part
1.32 4.71e-20 GO:0031981 nuclear lumen
1.29 4.15e-19 GO:0044428 nuclear part
1.16 1.27e-18 GO:0044446 intracellular organelle part
1.15 2.89e-18 GO:0044422 organelle part
1.27 2.31e-17 GO:0070013 intracellular organelle lumen
1.28 6.32e-17 GO:0005829 cytosol
1.25 4.70e-16 GO:0031974 membrane-enclosed lumen
1.25 1.04e-15 GO:0043233 organelle lumen
1.33 3.07e-14 GO:0005654 nucleoplasm
1.15 2.20e-08 GO:0032991 macromolecular complex
1.17 2.25e-08 GO:0043228 non-membrane-bounded organelle
1.17 2.25e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.70 5.43e-08 GO:0031252 cell leading edge
1.14 3.34e-06 GO:0043234 protein complex
1.35 7.88e-06 GO:0005694 chromosome
1.31 8.65e-06 GO:0015630 microtubule cytoskeleton
1.37 1.57e-05 GO:0044427 chromosomal part
1.29 3.89e-05 GO:0044451 nucleoplasm part
1.61 1.69e-04 GO:0005912 adherens junction
1.37 1.84e-04 GO:0043005 neuron projection
1.54 8.09e-04 GO:0070161 anchoring junction
1.14 1.03e-03 GO:0031090 organelle membrane
1.46 1.54e-03 GO:0000228 nuclear chromosome
1.85 2.06e-03 GO:0031256 leading edge membrane
1.69 3.83e-03 GO:0001726 ruffle
1.35 4.02e-03 GO:0005815 microtubule organizing center
1.26 4.60e-03 GO:0030054 cell junction
1.15 9.92e-03 GO:0012505 endomembrane system
1.39 1.29e-02 GO:0000785 chromatin
1.15 1.59e-02 GO:0005856 cytoskeleton
1.20 1.63e-02 GO:0042995 cell projection
1.42 1.66e-02 GO:0005911 cell-cell junction
1.44 2.80e-02 GO:0030424 axon
1.44 3.05e-02 GO:0044454 nuclear chromosome part
1.37 4.99e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 1.09e-37 GO:0005515 protein binding
1.08 6.22e-25 GO:0005488 binding
1.22 2.44e-11 GO:0000166 nucleotide binding
1.17 1.69e-10 GO:0003676 nucleic acid binding
1.30 3.63e-08 GO:0030528 transcription regulator activity
1.17 3.87e-06 GO:0003677 DNA binding
1.10 4.82e-06 GO:0003824 catalytic activity
1.19 7.07e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.18 7.71e-06 GO:0017076 purine nucleotide binding
1.18 8.55e-06 GO:0032553 ribonucleotide binding
1.18 8.55e-06 GO:0032555 purine ribonucleotide binding
1.26 1.53e-05 GO:0001071 nucleic acid binding transcription factor activity
1.26 1.53e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 2.38e-05 GO:0043565 sequence-specific DNA binding
1.27 4.75e-05 GO:0003723 RNA binding
1.41 4.14e-04 GO:0016563 transcription activator activity
1.26 5.96e-04 GO:0019899 enzyme binding
1.26 6.34e-04 GO:0016301 kinase activity
1.18 6.88e-04 GO:0030554 adenyl nucleotide binding
1.33 8.54e-04 GO:0030695 GTPase regulator activity
1.18 9.25e-04 GO:0005524 ATP binding
1.18 9.36e-04 GO:0032559 adenyl ribonucleotide binding
1.26 1.04e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 1.12e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.28 1.73e-03 GO:0004672 protein kinase activity
1.31 3.09e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.44 3.44e-03 GO:0019787 small conjugating protein ligase activity
1.52 4.71e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.38 5.21e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.31 5.34e-03 GO:0019904 protein domain specific binding
1.43 1.00e-02 GO:0004842 ubiquitin-protein ligase activity
1.15 1.05e-02 GO:0016740 transferase activity
1.39 1.14e-02 GO:0016881 acid-amino acid ligase activity
1.36 1.24e-02 GO:0016564 transcription repressor activity
1.30 1.53e-02 GO:0004674 protein serine/threonine kinase activity
1.39 2.79e-02 GO:0016791 phosphatase activity
1.30 3.83e-02 GO:0000988 protein binding transcription factor activity
1.30 3.83e-02 GO:0000989 transcription factor binding transcription factor activity
1.27 4.77e-02 GO:0016874 ligase activity