Motif ID: T.p2

Z-value: 0.986


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Tchr6_-_1665021190.581.8e-02Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_53769562 3.151 LOC100506779
hypothetical LOC100506779
chr2_+_171280046 2.119 NM_001003845
SP5
Sp5 transcription factor
chr11_-_110755112 1.946 POU2AF1
POU class 2 associating factor 1
chrX_+_128741562 1.923 NM_018990
SASH3
SAM and SH3 domain containing 3
chr6_+_167456230 1.817 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr9_-_37024358 1.703 NM_016734
PAX5
paired box 5
chr1_-_199259133 1.631 KIF21B
kinesin family member 21B
chr2_+_171280182 1.625


chrX_+_128741578 1.604 SASH3
SAM and SH3 domain containing 3
chr17_-_40858775 1.598 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr1_+_173111306 1.582 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr17_+_22823151 1.503 NM_014238
KSR1
kinase suppressor of ras 1
chr15_+_89248423 1.480 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr20_+_35406497 1.188 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr11_-_118405288 1.101 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr17_+_22982372 1.064 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_22982344 1.060 LGALS9
lectin, galactoside-binding, soluble, 9
chr2_-_100088760 1.032 AFF3
AF4/FMR2 family, member 3
chr2_-_151854619 1.001 NM_004688
NMI
N-myc (and STAT) interactor
chr3_+_47004457 0.977 NBEAL2
neurobeachin-like 2
chr17_-_20311411 0.974 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr17_+_22982383 0.968 LGALS9
lectin, galactoside-binding, soluble, 9
chr1_+_26609893 0.944 LIN28A
lin-28 homolog A (C. elegans)
chr1_-_114215768 0.943 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr17_+_22982278 0.926 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr17_+_31455332 0.915 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr17_+_22982319 0.910 LGALS9
lectin, galactoside-binding, soluble, 9
chrX_+_57329834 0.883 NM_174912
FAAH2
fatty acid amide hydrolase 2
chr3_-_19950675 0.870 NM_144715
EFHB
EF-hand domain family, member B
chr11_+_46358909 0.859 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr11_+_73037382 0.858 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_-_5536783 0.851 ACTB
actin, beta
chr19_-_60458915 0.830 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr19_+_2240996 0.791


chr19_-_45947667 0.791 NM_198476
C19orf54
chromosome 19 open reading frame 54
chr3_-_48573556 0.780 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr10_-_23043449 0.770 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr2_+_171280944 0.727 SP5
Sp5 transcription factor
chr6_+_33495824 0.712 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr19_+_17723285 0.711 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr7_-_5536704 0.672 NM_001101
ACTB
actin, beta
chr17_+_53761293 0.668 LOC100506779
hypothetical LOC100506779
chr16_-_4263056 0.648 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr7_-_16471817 0.619 NM_015464
SOSTDC1
sclerostin domain containing 1
chr12_-_121277972 0.612 NM_019887
NM_138929
DIABLO

diablo homolog (Drosophila)

chr11_-_33870411 0.611 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_-_145281237 0.598 NM_002099
GYPA
glycophorin A (MNS blood group)
chr2_-_169455167 0.591 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr6_-_130578110 0.583 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr20_-_22513050 0.570 NM_021784
FOXA2
forkhead box A2
chr4_-_145046109 0.564 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr8_-_145132582 0.551 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chrX_-_69426439 0.525 NM_016484
PDZD11
PDZ domain containing 11
chr6_-_31789824 0.518


chr15_-_81271859 0.513 NM_001007122
FSD2
fibronectin type III and SPRY domain containing 2
chr1_+_208008517 0.501 TRAF3IP3
TRAF3 interacting protein 3
chr17_-_59327602 0.497 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr2_+_176680251 0.484 NM_021192
HOXD11
homeobox D11
chr1_-_110949867 0.480 NM_004974
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr3_+_168936125 0.479 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr11_+_61279436 0.478 NM_013279
C11orf9
chromosome 11 open reading frame 9
chr11_-_124311512 0.462 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr1_-_246804680 0.459 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr15_-_88095363 0.459 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr4_-_145159889 0.453 NM_002100
GYPB
glycophorin B (MNS blood group)
chr5_+_176717553 0.437


chr5_+_179934143 0.433 CNOT6
CCR4-NOT transcription complex, subunit 6
chr20_-_51633042 0.429 NM_006526
ZNF217
zinc finger protein 217
chr16_+_29728932 0.426 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr15_-_38387266 0.424 PLCB2
phospholipase C, beta 2
chr10_+_70517823 0.417 NM_002727
SRGN
serglycin
chr17_-_24078075 0.411 NM_001160407
TLCD1
TLC domain containing 1
chr16_-_4262696 0.410 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr5_+_61750467 0.409 NM_001134779
IPO11
importin 11
chrX_-_106033202 0.400 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr22_-_30071761 0.391 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_-_87244896 0.391 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chrX_+_70360184 0.384 GJB1
gap junction protein, beta 1, 32kDa
chr10_-_76538859 0.380 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr7_+_99865340 0.378 MEPCE
methylphosphate capping enzyme
chr19_-_48976852 0.376 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr17_+_18320822 0.373 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr5_-_138753443 0.359 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr7_-_99604127 0.355 GAL3ST4
galactose-3-O-sulfotransferase 4
chr22_-_49363209 0.351 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr16_+_11966464 0.347 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_26986996 0.345 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr8_+_103633023 0.344 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr16_-_4263001 0.343 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr2_-_37397669 0.342 NM_005813
PRKD3
protein kinase D3
chr3_-_10307408 0.337 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr11_-_123816190 0.334 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr1_-_159306037 0.326 ARHGAP30
Rho GTPase activating protein 30
chr15_-_78050515 0.326 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr16_+_25135783 0.323 NM_001169
AQP8
aquaporin 8
chr17_-_59304729 0.322 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr5_-_39238818 0.319 FYB
FYN binding protein
chr10_+_94823636 0.310 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr2_-_174821530 0.308 NM_001011708
NM_013341
OLA1

Obg-like ATPase 1

chr2_-_102719732 0.308 NM_032718
MFSD9
major facilitator superfamily domain containing 9
chr16_+_75790849 0.306 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr14_-_23878871 0.296 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr2_+_37282516 0.291 LOC100505876
hypothetical LOC100505876
chr3_-_127719283 0.288 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chr6_+_109868897 0.285 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr11_+_68818175 0.284 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr3_+_139211639 0.283 NM_016369
CLDN18
claudin 18
chr6_+_132000134 0.283 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr1_+_157441133 0.282 NM_002036
DARC
Duffy blood group, chemokine receptor
chr21_-_14840506 0.278 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_-_117011824 0.278 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr19_+_7734034 0.274 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr1_-_152201814 0.271 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_151310707 0.271 NM_001017418
SPRR2B
small proline-rich protein 2B
chr1_+_26609819 0.269 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr1_+_33003814 0.261 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr1_-_159306369 0.254 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr1_+_28458546 0.251 NM_031459
SESN2
sestrin 2
chr5_-_132300702 0.251


chr15_+_89212888 0.244 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr8_-_42353719 0.243 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr10_+_70517863 0.242 SRGN
serglycin
chr7_+_148475373 0.240 NM_170686
ZNF398
zinc finger protein 398
chr7_+_142723340 0.236 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr8_-_74822496 0.235 NM_001164384
STAU2
staufen, RNA binding protein, homolog 2 (Drosophila)
chr14_+_71469538 0.234 NM_004296
RGS6
regulator of G-protein signaling 6
chr12_+_130004404 0.230 NM_198827
GPR133
G protein-coupled receptor 133
chr17_+_3047559 0.230 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr15_-_38387317 0.224 PLCB2
phospholipase C, beta 2
chr16_-_66523255 0.224 NM_001907
CTRL
chymotrypsin-like
chr18_-_72857951 0.223 MBP
myelin basic protein
chr2_-_68952006 0.222 NM_014482
BMP10
bone morphogenetic protein 10
chrX_+_152561086 0.220 NM_001395
DUSP9
dual specificity phosphatase 9
chr1_+_39229474 0.214 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr1_+_211190631 0.209 VASH2
vasohibin 2
chr1_-_151296611 0.208 NM_005988
SPRR2A
small proline-rich protein 2A
chr1_+_26973804 0.207 ARID1A
AT rich interactive domain 1A (SWI-like)
chr6_+_26266311 0.200 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr1_-_153109349 0.194 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr19_+_59973074 0.194 NM_014218
KIR2DS2
KIR2DL1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr5_+_96237923 0.193 ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_-_40335504 0.193 PPT1
palmitoyl-protein thioesterase 1
chr2_-_174821443 0.193 OLA1
Obg-like ATPase 1
chr16_+_67778441 0.193 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr19_+_60283571 0.192 NM_017729
EPS8L1
EPS8-like 1
chr10_-_98935369 0.191 SLIT1
slit homolog 1 (Drosophila)
chr2_-_174821503 0.189 OLA1
Obg-like ATPase 1
chr9_-_139564656 0.189 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chr4_+_154083584 0.189 NM_033393
FHDC1
FH2 domain containing 1
chr19_+_12805747 0.187 MAST1
microtubule associated serine/threonine kinase 1
chr21_-_33107813 0.181 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_-_159306210 0.180 ARHGAP30
Rho GTPase activating protein 30
chr1_+_154389945 0.176 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr18_-_72858037 0.174 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr17_+_77582774 0.172 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_-_59312892 0.170 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chr1_+_53253204 0.169 SCP2
sterol carrier protein 2
chr3_+_38282301 0.167 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr7_+_97199206 0.167 NM_003182
NM_013996
NM_013997
NM_013998
TAC1



tachykinin, precursor 1



chr17_+_31562577 0.166 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr1_+_111963920 0.163 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr12_+_21417068 0.162 NM_000415
IAPP
islet amyloid polypeptide
chr12_-_56312696 0.161 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr7_+_72913424 0.160 NM_182504
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr5_-_78318112 0.160 NM_000046
ARSB
arylsulfatase B
chr3_-_121065112 0.158


chr1_-_40335496 0.158 PPT1
palmitoyl-protein thioesterase 1
chr11_-_55815113 0.156 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr4_-_186969202 0.155 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr5_-_132140786 0.151 NM_001098811
NM_001098812
NM_015146
SEPT8


septin 8


chr1_-_23998515 0.151 NM_001127621
GALE
UDP-galactose-4-epimerase
chr1_+_179269761 0.151 MR1
major histocompatibility complex, class I-related
chr15_+_38648801 0.149 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr18_-_3209846 0.149 MYOM1
myomesin 1, 185kDa
chr22_+_38771317 0.148 TNRC6B
trinucleotide repeat containing 6B
chr3_-_196792274 0.147 NM_001647
APOD
apolipoprotein D
chr5_+_14717803 0.145 FAM105B
family with sequence similarity 105, member B
chr9_-_130124317 0.144 NM_015679
TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr7_-_36730525 0.141 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr7_+_2248966 0.141 NM_198953
NM_198954
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr1_-_159459814 0.140 APOA2
apolipoprotein A-II
chr1_+_559618 0.139


chr11_-_59707074 0.138 NM_022349
NM_152851
NM_152852
MS4A6A


membrane-spanning 4-domains, subfamily A, member 6A


chr11_-_113082233 0.134 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr17_-_59349867 0.134 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr1_+_1836125 0.134 NM_138705
CALML6
calmodulin-like 6
chr10_+_44726635 0.133 NM_001123376
TMEM72
transmembrane protein 72
chr1_+_51206963 0.131 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr19_-_17236522 0.130 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr17_+_43082302 0.129 KPNB1
karyopherin (importin) beta 1
chr1_-_180624380 0.129 GLUL
glutamate-ammonia ligase
chr1_+_33003847 0.127 KIAA1522
KIAA1522
chr7_-_75876830 0.127 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr11_-_17147863 0.126 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr19_-_17819773 0.124 JAK3
Janus kinase 3
chr19_-_17819814 0.124 NM_000215
JAK3
Janus kinase 3
chr2_-_174821486 0.123 OLA1
Obg-like ATPase 1
chr21_+_24722913 0.121 FLJ42200
FLJ42200 protein
chr1_-_153200880 0.121 NM_138300
PYGO2
pygopus homolog 2 (Drosophila)
chr8_-_74821610 0.119 STAU2
LOC729696
staufen, RNA binding protein, homolog 2 (Drosophila)
hypothetical protein LOC729696

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
39.91 6.23e-03 GO:0047023 androsterone dehydrogenase activity
39.91 6.23e-03 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity