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Motif ID: NHLH1,2.p2

Z-value: 3.041

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_109112428	8.359	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr7_+_17304707	6.231	NM_001621	AHR	aryl hydrocarbon receptor
chr9_-_83493415	4.432	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr12_-_74710741	4.404		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr3_-_73756668	4.339	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr2_-_229844198	4.278	NM_001100818 NM_017933	PID1	phosphotyrosine interaction domain containing 1
chr9_+_17124974	4.125	NM_001114395 NM_017738	CNTLN	centlein, centrosomal protein
chr11_-_6298284	3.862	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr13_-_25523164	3.604	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr4_-_40911212	3.430	NM_001166050 NM_004307 NM_173075	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_+_10597167	3.209	NM_020428	SLC44A2	solute carrier family 44, member 2
chr3_-_87122936	3.150	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr3_-_87122958	3.023		VGLL3	vestigial like 3 (Drosophila)
chr9_-_21549696	2.978		LOC554202	hypothetical LOC554202
chr7_-_45927263	2.928	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr13_-_43259032	2.878	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chrX_-_106846253	2.839	NM_001015881	TSC22D3	TSC22 domain family, member 3
chr13_+_113546841	2.809	NM_000820	GAS6	growth arrest-specific 6
chr17_+_56832492	2.762		TBX2	T-box 2
chr7_+_129919330	2.738		MEST	mesoderm specific transcript homolog (mouse)
chr5_-_58370693	2.721	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr2_+_29191711	2.712	NM_024692	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr5_+_129268352	2.704	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr7_+_55054416	2.703		EGFR	epidermal growth factor receptor
chr5_-_72779585	2.697		FOXD1	forkhead box D1
chr15_+_90738108	2.619	NM_006011	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr19_-_1083109	2.608	NM_001100122	SBNO2	strawberry notch homolog 2 (Drosophila)
chr6_+_129245978	2.572	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chrX_-_13866451	2.558		GPM6B	glycoprotein M6B
chr18_-_21185968	2.549		ZNF521	zinc finger protein 521
chr13_+_113546943	2.533		GAS6	growth arrest-specific 6
chr13_+_113546897	2.529		GAS6	growth arrest-specific 6
chr6_+_133604203	2.507		EYA4	eyes absent homolog 4 (Drosophila)
chr14_+_22375753	2.489		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr1_-_59020875	2.453		JUN	jun proto-oncogene
chr1_+_77520315	2.428	NM_174858	AK5	adenylate kinase 5
chr9_-_71476917	2.426	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr10_+_112247614	2.424	NM_004419	DUSP5	dual specificity phosphatase 5
chr8_+_97575370	2.376		SDC2	syndecan 2
chr1_+_68070573	2.368
chr1_-_115682374	2.360	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr14_-_88090641	2.358	NM_007039	PTPN21	protein tyrosine phosphatase, non-receptor type 21
chr2_-_227371698	2.358	NM_005544	IRS1	insulin receptor substrate 1
chr11_+_7997366	2.318		TUB	tubby homolog (mouse)
chr1_-_85703321	2.244	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr13_-_95094920	2.225	NM_014934 NM_198968	DZIP1	DAZ interacting protein 1
chr1_-_158091296	2.212		C1orf204	chromosome 1 open reading frame 204
chr10_+_17311307	2.211		VIM	vimentin
chr6_+_3696224	2.191
chr10_+_17311283	2.190		VIM	vimentin
chr10_+_17311347	2.187		VIM	vimentin
chr13_-_76358370	2.179		KCTD12	potassium channel tetramerisation domain containing 12
chr9_-_35679799	2.175		TPM2	tropomyosin 2 (beta)
chr12_+_51730101	2.167	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr17_-_15106579	2.160		PMP22	peripheral myelin protein 22
chr17_-_15106597	2.150	NM_153321	PMP22	peripheral myelin protein 22
chr12_-_29827952	2.149	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr11_+_110916629	2.148		LAYN	layilin
chr6_-_82518576	2.141		FAM46A	family with sequence similarity 46, member A
chr14_-_51605487	2.139		NID2	nidogen 2 (osteonidogen)
chr22_-_22652018	2.136	NM_001355	DDT	D-dopachrome tautomerase
chr10_+_17311242	2.133		VIM	vimentin
chr19_-_50977485	2.127		DMPK	dystrophia myotonica-protein kinase
chr9_-_35679902	2.120	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chr9_-_25668230	2.115		TUSC1	tumor suppressor candidate 1
chr14_-_51605461	2.113		NID2	nidogen 2 (osteonidogen)
chr6_-_105691675	2.110		BVES	blood vessel epicardial substance
chr10_+_17311282	2.097		VIM	vimentin
chr3_+_11171213	2.096	NM_001098212	HRH1	histamine receptor H1
chr8_-_82186832	2.075	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1
chr5_-_178704934	2.074		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr18_-_53621277	2.071	NM_005603	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr9_-_21999270	2.063	NM_004936 NM_078487	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_+_86189138	2.021	NM_007173	PRSS23	protease, serine, 23
chr11_+_12355600	2.020	NM_018222	PARVA	parvin, alpha
chr5_-_136862130	2.010		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr3_-_147361465	1.986		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_+_216586199	1.957		TGFB2	transforming growth factor, beta 2
chr10_+_124211353	1.946		HTRA1	HtrA serine peptidase 1
chr1_-_199704773	1.942	NM_012396	PHLDA3	pleckstrin homology-like domain, family A, member 3
chr10_+_99463446	1.931	NM_031484	MARVELD1	MARVEL domain containing 1
chr4_-_57671307	1.910		IGFBP7	insulin-like growth factor binding protein 7
chr16_-_71650034	1.904	NM_001164766	ZFHX3	zinc finger homeobox 3
chr3_+_49034050	1.903	NM_199069 NM_199070	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr17_+_1906262	1.900	NM_001098202	HIC1	hypermethylated in cancer 1
chr13_-_73606362	1.892		KLF12	Kruppel-like factor 12
chr5_+_102229612	1.882		PAM	peptidylglycine alpha-amidating monooxygenase
chr14_-_51605515	1.879		NID2	nidogen 2 (osteonidogen)
chr1_-_95165089	1.877	NM_001839	CNN3	calponin 3, acidic
chr9_-_130980359	1.864	NM_203434	IER5L	immediate early response 5-like
chr1_-_72520735	1.861	NM_173808	NEGR1	neuronal growth regulator 1
chr12_-_67613213	1.845	NM_001005502 NM_198320	CPM	carboxypeptidase M
chr12_+_64504835	1.828		HMGA2	high mobility group AT-hook 2
chr4_+_86968069	1.818		ARHGAP24	Rho GTPase activating protein 24
chr3_+_30623376	1.799		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr13_-_35603466	1.799		DCLK1	doublecortin-like kinase 1
chr6_+_17389752	1.794	NM_001143942	RBM24	RNA binding motif protein 24
chr7_+_129919157	1.792	NM_002402	MEST	mesoderm specific transcript homolog (mouse)
chr6_-_105691235	1.790	NM_007073	BVES	blood vessel epicardial substance
chr10_+_99463468	1.788		MARVELD1	MARVEL domain containing 1
chr11_+_106967283	1.783		ELMOD1	ELMO/CED-12 domain containing 1
chr2_+_149895274	1.776	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr7_+_129919134	1.775		MEST	mesoderm specific transcript homolog (mouse)
chr3_+_160964574	1.762		SCHIP1	schwannomin interacting protein 1
chr14_+_58174489	1.755	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr1_-_33420213	1.750	NM_018207	TRIM62	tripartite motif containing 62
chr11_-_86060812	1.749	NM_001014811	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chrX_-_13866366	1.744
chr1_+_31658549	1.738	NM_178865	SERINC2	serine incorporator 2
chr7_-_130891861	1.729	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr6_-_82519093	1.721	NM_017633	FAM46A	family with sequence similarity 46, member A
chr1_+_238321794	1.720	NM_020066	FMN2	formin 2
chr19_-_63301402	1.714		ZSCAN18	zinc finger and SCAN domain containing 18
chr21_+_45318861	1.711	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr16_+_27320983	1.704	NM_181078 NM_181079	IL21R	interleukin 21 receptor
chr11_+_133444175	1.686		JAM3	junctional adhesion molecule 3
chr1_-_84237316	1.685	NM_024686	TTLL7	tubulin tyrosine ligase-like family, member 7
chr5_-_178705036	1.684	NM_014244 NM_021599	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr4_+_158216631	1.675	NM_000824 NM_001166061 NM_001166060	GLRB	glycine receptor, beta
chr18_-_21186107	1.675	NM_015461	ZNF521	zinc finger protein 521
chr4_-_86106567	1.668	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr5_+_102229425	1.652	NM_000919 NM_001177306 NM_138766 NM_138821 NM_138822	PAM	peptidylglycine alpha-amidating monooxygenase
chr19_-_63301386	1.651		ZSCAN18	zinc finger and SCAN domain containing 18
chr11_-_86061003	1.645	NM_006680	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chr12_-_26166485	1.640		BHLHE41	basic helix-loop-helix family, member e41
chr8_+_97575196	1.639		SDC2	syndecan 2
chr2_-_19421852	1.634	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr11_+_124539814	1.633		PKNOX2	PBX/knotted 1 homeobox 2
chr8_+_97575244	1.633		SDC2	syndecan 2
chr2_-_37752731	1.621	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr19_-_63301418	1.619	NM_001145543 NM_001145544 NM_023926	ZSCAN18	zinc finger and SCAN domain containing 18
chr13_-_35603513	1.616	NM_004734	DCLK1	doublecortin-like kinase 1
chr4_-_57671273	1.611	NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chrX_-_13866565	1.611	NM_001001994	GPM6B	glycoprotein M6B
chr1_-_143750988	1.611	NM_001198832	PDE4DIP	phosphodiesterase 4D interacting protein
chr13_-_35603432	1.611		DCLK1	doublecortin-like kinase 1
chr14_-_37795290	1.611	NM_175060	CLEC14A	C-type lectin domain family 14, member A
chr13_-_73605914	1.610	NM_007249	KLF12	Kruppel-like factor 12
chr17_+_56832255	1.601		TBX2	T-box 2
chr6_+_142664490	1.597	NM_001032394 NM_001032395 NM_020455 NM_198569	GPR126	G protein-coupled receptor 126
chr1_-_56817717	1.597		PPAP2B	phosphatidic acid phosphatase type 2B
chr14_+_99220349	1.585	NM_006668	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr9_-_128924706	1.583		ANGPTL2	angiopoietin-like 2
chr12_+_27824429	1.576	NM_020782	KLHDC5	kelch domain containing 5
chr13_-_22905822	1.574	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chrX_+_152699616	1.567	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr17_-_19711580	1.563	NM_001142610 NM_014683	ULK2	unc-51-like kinase 2 (C. elegans)
chr11_+_124539768	1.562	NM_022062	PKNOX2	PBX/knotted 1 homeobox 2
chr4_-_140696740	1.559	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr2_+_5750229	1.559	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr4_-_186934059	1.558	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr13_+_113546912	1.533		GAS6	growth arrest-specific 6
chr3_-_79151232	1.529	NM_001145845 NM_133631	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr9_-_128924782	1.527		ANGPTL2	angiopoietin-like 2
chr3_-_151171576	1.522		PFN2	profilin 2
chr11_-_65841077	1.511	NM_020404	CD248	CD248 molecule, endosialin
chr2_+_191818124	1.507	NM_001130158 NM_012223 NM_001161819	MYO1B	myosin IB
chr2_-_219404755	1.506	NM_017431	PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr14_+_22375747	1.506		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr1_+_15145001	1.497	NM_001017999	KAZN	kazrin, periplakin interacting protein
chr15_+_72006015	1.496		LOXL1	lysyl oxidase-like 1
chr10_+_17311788	1.489		VIM	vimentin
chr9_+_133154896	1.486	NM_032728	PPAPDC3	phosphatidic acid phosphatase type 2 domain containing 3
chr17_-_53387493	1.485		CUEDC1	CUE domain containing 1
chr12_+_121233615	1.485	NM_001098519	LRRC43	leucine rich repeat containing 43
chr7_-_84654106	1.485		SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr1_-_22136263	1.484	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr10_+_27833167	1.476	NM_021252	RAB18	RAB18, member RAS oncogene family
chr15_+_89228668	1.468	NM_001143785 NM_002005	FES	feline sarcoma oncogene
chr8_-_72918697	1.463		MSC	musculin
chr2_+_56265260	1.460
chr17_-_7434113	1.456	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr11_+_44543716	1.455	NM_001024844 NM_002231	CD82	CD82 molecule
chr1_-_72521079	1.455
chr9_-_128924819	1.454	NM_012098	ANGPTL2	angiopoietin-like 2
chr3_+_151171755	1.444		LOC646903	hypothetical LOC646903
chr3_+_8518508	1.437	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr19_-_50977586	1.422		DMPK	dystrophia myotonica-protein kinase
chr17_-_63965156	1.418	NM_017983	WIPI1	WD repeat domain, phosphoinositide interacting 1
chr3_+_49034494	1.417		NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr7_+_27102508	1.411
chr14_+_62740878	1.409	NM_020663	RHOJ	ras homolog gene family, member J
chr6_-_119079712	1.409	NM_001042475 NM_206921	C6orf204	chromosome 6 open reading frame 204
chr9_+_111582317	1.405	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr3_-_31997738	1.398		OSBPL10	oxysterol binding protein-like 10
chrX_+_73557809	1.393	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr5_-_136862317	1.387		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr15_-_58671929	1.370	NM_134262	RORA	RAR-related orphan receptor A
chr9_-_16860664	1.362		BNC2	basonuclin 2
chr9_+_71848555	1.355		MAMDC2	MAM domain containing 2
chr19_-_50977592	1.351	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr5_-_54317102	1.345	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr5_-_112658200	1.341		MCC	mutated in colorectal cancers
chr7_-_27136876	1.341	NM_002141	HOXA4	homeobox A4
chr12_-_94708477	1.338		NTN4	netrin 4
chr12_+_50587468	1.333	NM_000020	ACVRL1	activin A receptor type II-like 1
chr17_+_36515166	1.333	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr15_-_90999606	1.331	NM_207446	FAM174B	family with sequence similarity 174, member B
chr10_+_72642274	1.329	NM_170744	UNC5B	unc-5 homolog B (C. elegans)
chr3_+_100840129	1.325	NM_001850 NM_020351	COL8A1	collagen, type VIII, alpha 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.34	1.22e-08	GO:0023051	regulation of signaling
1.21	1.59e-08	GO:0032502	developmental process
1.36	2.00e-08	GO:0009653	anatomical structure morphogenesis
1.23	2.08e-08	GO:0048856	anatomical structure development
1.22	2.25e-08	GO:0007275	multicellular organismal development
1.13	5.38e-08	GO:0050794	regulation of cellular process
1.21	4.83e-07	GO:0007165	signal transduction
1.40	5.21e-07	GO:0010646	regulation of cell communication
1.12	5.88e-07	GO:0050789	regulation of biological process
1.34	6.69e-07	GO:0009966	regulation of signal transduction
1.23	7.35e-07	GO:0048731	system development
1.26	2.37e-06	GO:0048869	cellular developmental process
1.11	2.42e-06	GO:0065007	biological regulation
1.32	2.62e-06	GO:0007399	nervous system development
1.41	4.85e-06	GO:0022008	neurogenesis
1.60	5.57e-06	GO:0048812	neuron projection morphogenesis
1.45	5.83e-06	GO:2000026	regulation of multicellular organismal development
1.18	5.90e-06	GO:0023052	signaling
1.60	5.90e-06	GO:0048667	cell morphogenesis involved in neuron differentiation
1.26	5.98e-06	GO:0030154	cell differentiation
1.61	6.59e-06	GO:0007409	axonogenesis
1.57	9.44e-06	GO:0072358	cardiovascular system development
1.57	9.44e-06	GO:0072359	circulatory system development
1.48	1.22e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.55	1.70e-05	GO:0000904	cell morphogenesis involved in differentiation
1.54	1.78e-05	GO:0048858	cell projection morphogenesis
1.41	2.20e-05	GO:0048699	generation of neurons
1.47	2.93e-05	GO:0032989	cellular component morphogenesis
1.69	3.18e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.53	3.44e-05	GO:0032990	cell part morphogenesis
1.38	3.81e-05	GO:0048468	cell development
1.44	5.14e-05	GO:0030182	neuron differentiation
1.32	5.89e-05	GO:0051239	regulation of multicellular organismal process
1.48	7.47e-05	GO:0048666	neuron development
1.69	7.92e-05	GO:0001944	vasculature development
1.52	8.74e-05	GO:0031175	neuron projection development
1.47	9.81e-05	GO:0000902	cell morphogenesis
1.23	1.27e-04	GO:0048523	negative regulation of cellular process
1.45	1.56e-04	GO:0030030	cell projection organization
1.36	2.37e-04	GO:0050793	regulation of developmental process
1.21	3.20e-04	GO:0048519	negative regulation of biological process
1.60	6.01e-04	GO:0007411	axon guidance
1.14	1.03e-03	GO:0051716	cellular response to stimulus
1.46	1.51e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.06	1.57e-03	GO:0009987	cellular process
1.63	2.46e-03	GO:0001568	blood vessel development
1.60	4.16e-03	GO:0061061	muscle structure development
1.31	5.44e-03	GO:0009605	response to external stimulus
1.22	6.22e-03	GO:0007166	cell surface receptor linked signaling pathway
1.25	1.13e-02	GO:0035556	intracellular signal transduction
1.33	1.18e-02	GO:0051128	regulation of cellular component organization
1.32	1.23e-02	GO:0040011	locomotion
1.21	1.45e-02	GO:0048583	regulation of response to stimulus
1.87	2.07e-02	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.62	3.01e-02	GO:0048514	blood vessel morphogenesis
1.17	4.40e-02	GO:0048522	positive regulation of cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	4.39e-07	GO:0005737	cytoplasm
1.06	3.01e-05	GO:0044424	intracellular part
1.06	3.36e-05	GO:0005622	intracellular
1.83	3.36e-05	GO:0031252	cell leading edge
1.82	5.35e-04	GO:0005912	adherens junction
1.99	3.16e-03	GO:0001726	ruffle
1.70	4.63e-03	GO:0070161	anchoring junction
1.89	5.66e-03	GO:0005924	cell-substrate adherens junction
1.82	1.68e-02	GO:0030055	cell-substrate junction
1.17	1.79e-02	GO:0044459	plasma membrane part
1.84	2.27e-02	GO:0005925	focal adhesion
1.32	3.33e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	2.40e-06	GO:0005515	protein binding
1.05	6.81e-04	GO:0005488	binding
1.51	4.82e-03	GO:0003779	actin binding
1.37	1.15e-02	GO:0008092	cytoskeletal protein binding
1.30	2.15e-02	GO:0019899	enzyme binding
1.39	3.31e-02	GO:0019904	protein domain specific binding