Motif ID: MAZ.p2

Z-value: 2.572


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297253110.802.0e-04Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_26895108 4.774 NM_006015
NM_139135
 ARID1A

AT rich interactive domain 1A (SWI-like)

chr5_+_139008209 4.491 NM_016463
 CXXC5
CXXC finger protein 5
chr2_-_25328452 4.149 NM_153759
 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_+_61841662 3.883 SLC2A4RG
SLC2A4 regulator
chrX_+_9392980 3.789 NM_005647
 TBL1X
transducin (beta)-like 1X-linked
chr8_+_144706699 3.741 NM_001166237
 GSDMD
gasdermin D
chr20_-_34635091 3.427


chr20_+_61841553 3.177 NM_020062
 SLC2A4RG
SLC2A4 regulator
chr19_-_55524445 3.032 NM_004977
 KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr9_+_70509925 2.960 NM_003558
 PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_-_39652449 2.902 NM_001076684
 UBTF
upstream binding transcription factor, RNA polymerase I
chr19_+_659766 2.764 NM_001040134
NM_002579
 PALM

paralemmin

chr14_-_21064182 2.750 SALL2
sal-like 2 (Drosophila)
chr1_-_32574185 2.709 NM_023009
 MARCKSL1
MARCKS-like 1
chrX_+_138060 2.579 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr15_+_38550451 2.578 NM_130468
 CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr16_+_49139694 2.494 NM_033119
 NKD1
naked cuticle homolog 1 (Drosophila)
chr12_+_56291484 2.467 NM_182947
 ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr5_+_139008667 2.462 CXXC5
CXXC finger protein 5
chr20_+_34635362 2.461 NM_021809
 TGIF2
TGFB-induced factor homeobox 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 120 entries
enrichment   p-value GO term description
1.77 1.03e-03 GO:0018393 internal peptidyl-lysine acetylation
1.76 1.84e-03 GO:0016573 histone acetylation
1.75 1.30e-03 GO:0006475 internal protein amino acid acetylation
1.74 2.29e-03 GO:0018394 peptidyl-lysine acetylation
1.66 9.33e-03 GO:0006338 chromatin remodeling
1.61 4.78e-02 GO:0006473 protein acetylation
1.57 4.75e-02 GO:0018205 peptidyl-lysine modification
1.50 6.73e-05 GO:0016569 covalent chromatin modification
1.50 9.75e-05 GO:0016570 histone modification
1.48 2.31e-02 GO:0051789 response to protein stimulus
1.44 1.36e-08 GO:0016568 chromatin modification
1.43 5.82e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.41 1.51e-07 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.40 6.38e-12 GO:0010629 negative regulation of gene expression
1.38 4.13e-09 GO:0045892 negative regulation of transcription, DNA-dependent
1.37 1.52e-08 GO:0051253 negative regulation of RNA metabolic process
1.36 3.57e-09 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 9.55e-03 GO:0016567 protein ubiquitination
1.35 4.75e-09 GO:0051172 negative regulation of nitrogen compound metabolic process
1.35 8.65e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
1.89 1.84e-03 GO:0000118 histone deacetylase complex
1.70 1.21e-03 GO:0000123 histone acetyltransferase complex
1.63 2.32e-04 GO:0016585 chromatin remodeling complex
1.39 1.06e-02 GO:0043025 neuronal cell body
1.36 2.84e-02 GO:0044297 cell body
1.34 3.70e-02 GO:0030425 dendrite
1.32 4.38e-02 GO:0000228 nuclear chromosome
1.28 2.52e-07 GO:0044451 nucleoplasm part
1.27 8.87e-05 GO:0005694 chromosome
1.26 2.38e-12 GO:0005654 nucleoplasm
1.26 7.76e-03 GO:0043005 neuron projection
1.24 1.49e-15 GO:0031981 nuclear lumen
1.23 3.67e-17 GO:0044428 nuclear part
1.23 1.74e-02 GO:0044427 chromosomal part
1.22 1.43e-16 GO:0070013 intracellular organelle lumen
1.21 5.86e-16 GO:0043233 organelle lumen
1.21 3.12e-15 GO:0031974 membrane-enclosed lumen
1.21 1.71e-13 GO:0005829 cytosol
1.21 3.10e-03 GO:0015630 microtubule cytoskeleton
1.14 6.85e-23 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
1.43 6.32e-04 GO:0003682 chromatin binding
1.41 3.37e-06 GO:0008134 transcription factor binding
1.36 1.40e-04 GO:0016564 transcription repressor activity
1.33 5.27e-06 GO:0019904 protein domain specific binding
1.33 1.36e-04 GO:0000988 protein binding transcription factor activity
1.33 1.36e-04 GO:0000989 transcription factor binding transcription factor activity
1.32 1.83e-04 GO:0003712 transcription cofactor activity
1.32 3.24e-02 GO:0019900 kinase binding
1.30 3.67e-09 GO:0019899 enzyme binding
1.27 4.21e-06 GO:0043565 sequence-specific DNA binding
1.24 7.57e-08 GO:0030528 transcription regulator activity
1.21 4.57e-05 GO:0001071 nucleic acid binding transcription factor activity
1.21 4.57e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 2.22e-02 GO:0003723 RNA binding
1.18 2.95e-02 GO:0042802 identical protein binding
1.14 3.09e-31 GO:0005515 protein binding
1.14 3.83e-06 GO:0003677 DNA binding
1.13 3.61e-08 GO:0003676 nucleic acid binding
1.12 1.13e-03 GO:0000166 nucleotide binding
1.11 2.45e-02 GO:0008270 zinc ion binding