Motif ID: ZEB1.p2

Z-value: 3.623


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_31648103-0.811.3e-04Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_22363036 8.870 NM_012294
 RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr19_+_6415259 8.786 NM_139161
NM_174881
 CRB3

crumbs homolog 3 (Drosophila)

chr19_+_40431359 8.259 NM_015925
NM_205834
NM_205835
 LSR


lipolysis stimulated lipoprotein receptor


chr19_+_40431618 8.197 LSR
lipolysis stimulated lipoprotein receptor
chr1_-_27159462 7.743 NM_152365
 C1orf172
chromosome 1 open reading frame 172
chr8_+_120289735 7.661 NM_052886
 MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr22_+_38720881 7.568 NM_138435
 FAM83F
family with sequence similarity 83, member F
chr4_-_35922288 7.358 NM_015230
 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_+_43447262 6.873 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_40431122 5.969 LSR
lipolysis stimulated lipoprotein receptor
chr8_-_144887876 5.887 NM_198488
 FAM83H
family with sequence similarity 83, member H
chr19_+_40431678 5.768 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_43447078 5.661 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr18_+_27332024 5.040 NM_001943
 DSG2
desmoglein 2
chr1_-_208046011 5.033 NM_006147
 IRF6
interferon regulatory factor 6
chr19_+_43446937 4.957 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_7566698 4.859 NM_001080429
NM_020902
 KIAA1543

KIAA1543

chr7_+_26298018 4.853 NM_013322
 SNX10
sorting nexin 10
chr17_+_26839143 4.548 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr11_+_32808045 4.384 NM_024081
 PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.31 2.38e-02 GO:0006793 phosphorus metabolic process
1.31 2.38e-02 GO:0006796 phosphate metabolic process
1.11 4.33e-04 GO:0008152 metabolic process
1.11 3.00e-03 GO:0044238 primary metabolic process
1.11 4.09e-03 GO:0044237 cellular metabolic process
1.06 6.25e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.28 1.99e-02 GO:0005794 Golgi apparatus
1.23 1.75e-04 GO:0005829 cytosol
1.23 6.62e-03 GO:0012505 endomembrane system
1.17 4.20e-02 GO:0031090 organelle membrane
1.14 2.94e-12 GO:0005737 cytoplasm
1.13 9.61e-06 GO:0044444 cytoplasmic part
1.11 6.29e-03 GO:0044446 intracellular organelle part
1.10 1.77e-02 GO:0044422 organelle part
1.07 6.39e-07 GO:0005622 intracellular
1.07 1.06e-05 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.39 3.98e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.37 1.26e-03 GO:0016301 kinase activity
1.35 1.30e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.26 1.24e-04 GO:0016740 transferase activity
1.23 1.28e-03 GO:0032553 ribonucleotide binding
1.23 1.28e-03 GO:0032555 purine ribonucleotide binding
1.23 1.31e-03 GO:0017076 purine nucleotide binding
1.22 3.07e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.22 2.16e-02 GO:0030554 adenyl nucleotide binding
1.22 2.37e-02 GO:0032559 adenyl ribonucleotide binding
1.22 3.56e-02 GO:0005524 ATP binding
1.18 1.98e-02 GO:0000166 nucleotide binding
1.12 1.19e-06 GO:0005515 protein binding
1.11 2.23e-02 GO:0003824 catalytic activity