Motif ID: TFCP2.p2

Z-value: 3.500


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
TFCP2 7024 transcription factor CP2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFCP2chr12_-_49852858-0.457.7e-02Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_8060762 4.068 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr17_+_56831951 3.937 NM_005994
TBX2
T-box 2
chr17_+_56832255 3.934 TBX2
T-box 2
chr19_-_1518875 3.355 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr17_+_56832492 3.263 TBX2
T-box 2
chr7_-_139987044 2.903 DENND2A
DENN/MADD domain containing 2A
chr11_-_70641267 2.749 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_+_16929116 2.646 NM_181723
EFHA2
EF-hand domain family, member A2
chr14_-_99842519 2.466 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr2_+_238712101 2.463 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr11_-_65841077 2.453 NM_020404
CD248
CD248 molecule, endosialin
chr11_+_64838882 2.383 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr2_+_42128521 2.362 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr15_-_23659329 2.269 NM_024490
ATP10A
ATPase, class V, type 10A
chr20_-_17610828 2.228 NM_001042576
NM_004587
RRBP1

ribosome binding protein 1 homolog 180kDa (dog)

chr5_+_63497408 2.075 NM_001113561
NM_178532
RNF180

ring finger protein 180

chr20_-_17610704 1.953 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr2_-_161058550 1.951 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr2_-_128792515 1.938 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr11_+_76455574 1.934 NM_004055
CAPN5
calpain 5
chr9_-_35062643 1.924 NM_007126
VCP
valosin containing protein
chr2_-_161058120 1.923 RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_+_21128614 1.868 MAP2K3
mitogen-activated protein kinase kinase 3
chr15_+_78858763 1.804 NM_018689
KIAA1199
KIAA1199
chr15_+_66658626 1.788 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr14_-_51605487 1.765 NID2
nidogen 2 (osteonidogen)
chr1_+_78126787 1.727 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr13_-_20533629 1.719 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr17_-_44022595 1.712 HOXB3
homeobox B3
chr3_+_129690735 1.702


chr14_-_51605461 1.624 NID2
nidogen 2 (osteonidogen)
chr9_+_136673534 1.607 COL5A1
collagen, type V, alpha 1
chr17_+_21128625 1.605 MAP2K3
mitogen-activated protein kinase kinase 3
chr3_-_121652183 1.591 NM_007085
FSTL1
follistatin-like 1
chr14_-_37795001 1.589 CLEC14A
C-type lectin domain family 14, member A
chr14_-_51605515 1.579 NID2
nidogen 2 (osteonidogen)
chr13_-_49597776 1.565 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr1_-_1465602 1.562 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr2_+_9532087 1.552 NM_001039613
IAH1
isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr11_-_118716736 1.548 C1QTNF5
MFRP
C1q and tumor necrosis factor related protein 5
membrane frizzled-related protein
chr5_-_37285160 1.532 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr8_+_59069522 1.525 NM_147189
FAM110B
family with sequence similarity 110, member B
chr22_+_40800193 1.501 NM_001002034
FAM109B
family with sequence similarity 109, member B
chr17_-_17340219 1.498 NM_016084
RASD1
RAS, dexamethasone-induced 1
chr19_-_12007485 1.495 ZNF433
zinc finger protein 433
chr14_+_23908141 1.490 NM_001198966
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr17_-_959007 1.482 NM_001092
ABR
active BCR-related gene
chr17_-_71023048 1.481 CASKIN2
CASK interacting protein 2
chr14_-_60185659 1.475 NM_005982
SIX1
SIX homeobox 1
chr4_+_4912272 1.458 NM_002448
MSX1
msh homeobox 1
chr3_+_61522922 1.448 PTPRG
protein tyrosine phosphatase, receptor type, G
chr3_+_160964574 1.444 SCHIP1
schwannomin interacting protein 1
chr17_+_21128560 1.418 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr18_+_2836979 1.413 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr17_-_36451189 1.402 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr11_+_120399966 1.401 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr1_-_45444812 1.389 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr14_+_68796621 1.389 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr2_+_54537842 1.388 SPTBN1
spectrin, beta, non-erythrocytic 1
chr20_-_62071584 1.387 NM_020713
ZNF512B
zinc finger protein 512B
chr19_-_12007503 1.383 NM_001080411
ZNF433
zinc finger protein 433
chr1_+_200124620 1.372 SHISA4
shisa homolog 4 (Xenopus laevis)
chr11_-_118716244 1.365 MFRP
membrane frizzled-related protein
chr17_-_63798851 1.364 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr20_+_44771532 1.362 NM_030777
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr13_-_20533703 1.359 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr16_+_2025922 1.351 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_-_135575925 1.349 NM_016201
AMOTL2
angiomotin like 2
chr1_-_925332 1.340 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr1_-_95165089 1.332 NM_001839
CNN3
calponin 3, acidic
chr17_+_56888588 1.311 NM_018488
TBX4
T-box 4
chr18_+_7557313 1.308 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr10_+_31648103 1.291 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr19_+_12036513 1.275 NM_001136501
ZNF844
zinc finger protein 844
chr17_-_71023221 1.264 NM_020753
CASKIN2
CASK interacting protein 2
chr6_+_36206239 1.251 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr9_-_19117494 1.245 NM_001122
PLIN2
perilipin 2
chr2_-_11402150 1.243 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr13_-_113916066 1.237 RASA3
RAS p21 protein activator 3
chrX_+_152644385 1.225 ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chrX_+_53095230 1.223 NM_018969
GPR173
G protein-coupled receptor 173
chr14_+_51188289 1.218 NM_152330
FRMD6
FERM domain containing 6
chr17_-_4216359 1.216 UBE2G1
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)
chr16_-_69277355 1.213 NM_138383
MTSS1L
metastasis suppressor 1-like
chr13_-_113916186 1.210 NM_007368
RASA3
RAS p21 protein activator 3
chr7_+_79602023 1.209 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr13_-_113916115 1.202 RASA3
RAS p21 protein activator 3
chr7_+_78920846 1.194 LOC100505881
hypothetical LOC100505881
chr16_+_15435825 1.189 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr19_-_12266592 1.174 NM_001164276
NM_016264
ZNF44

zinc finger protein 44

chr2_-_218516950 1.172 NM_022648
TNS1
tensin 1
chr21_-_38210531 1.165 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr1_+_200124412 1.164 NM_198149
SHISA4
shisa homolog 4 (Xenopus laevis)
chr3_+_184836049 1.150 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chr13_-_113916159 1.147 RASA3
RAS p21 protein activator 3
chr14_-_51605695 1.142 NM_007361
NID2
nidogen 2 (osteonidogen)
chr10_+_52421120 1.139 PRKG1
protein kinase, cGMP-dependent, type I
chr19_+_2427122 1.131 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr17_+_71892538 1.129 SPHK1
sphingosine kinase 1
chr3_+_185515108 1.129 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_35431329 1.127 NM_005066
SFPQ
splicing factor proline/glutamine-rich
chr6_+_108988761 1.125 NM_001455
FOXO3
forkhead box O3
chr14_-_68515731 1.122 ACTN1
actinin, alpha 1
chr10_+_52504239 1.118 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr17_+_63799228 1.117 ARSG
arylsulfatase G
chr19_-_47155277 1.115 RABAC1
Rab acceptor 1 (prenylated)
chr9_-_137531517 1.110 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr7_-_99594265 1.097 C7orf43
chromosome 7 open reading frame 43
chr9_-_83494198 1.089 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr19_-_47155340 1.074 NM_006423
RABAC1
Rab acceptor 1 (prenylated)
chr12_+_13045702 1.070 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr16_+_66121040 1.067 NM_001193523
FAM65A
family with sequence similarity 65, member A
chr3_+_121296290 1.067


chr5_-_146813343 1.065 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr10_-_31647925 1.054 LOC220930
hypothetical LOC220930
chr1_-_232811846 1.051 NM_001077397
NM_182972
IRF2BP2

interferon regulatory factor 2 binding protein 2

chr15_-_58671929 1.043 NM_134262
RORA
RAR-related orphan receptor A
chr13_-_112392051 1.038 LOC440149
hypothetical LOC440149
chr1_-_35431318 1.037 SFPQ
splicing factor proline/glutamine-rich
chr8_+_37672427 1.034 NM_025069
ZNF703
zinc finger protein 703
chr18_+_18969724 1.032 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr9_-_35062596 1.032 VCP
valosin containing protein
chr17_-_39211706 1.030 NM_004090
DUSP3
dual specificity phosphatase 3
chr13_-_36392370 1.029 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr19_-_11390948 1.025 NM_001035223
NM_001161616
RGL3

ral guanine nucleotide dissociation stimulator-like 3

chr19_-_20011013 1.025 NM_001077349
ZNF682
zinc finger protein 682
chr16_-_2521359 1.022 NM_001048212
CEMP1
cementum protein 1
chr14_-_68515742 1.012 ACTN1
actinin, alpha 1
chr1_-_160260210 1.011 NM_015441
OLFML2B
olfactomedin-like 2B
chr2_+_130830049 1.009 NM_001142370
NM_014369
PTPN18

protein tyrosine phosphatase, non-receptor type 18 (brain-derived)

chr19_-_9790502 1.009 FBXL12
F-box and leucine-rich repeat protein 12
chr18_+_65219114 1.004 NM_152721
DOK6
docking protein 6
chr21_+_46226072 1.004 NM_001848
COL6A1
collagen, type VI, alpha 1
chr2_-_227371698 0.995 NM_005544
IRS1
insulin receptor substrate 1
chr3_+_32408346 0.991 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr2_+_149895274 0.990 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr14_+_95575319 0.989 C14orf132
chromosome 14 open reading frame 132
chr2_+_241944333 0.989 NM_014808
FARP2
FERM, RhoGEF and pleckstrin domain protein 2
chr17_+_38719371 0.981 NM_145041
TMEM106A
FLJ77644
transmembrane protein 106A
hypothetical LOC728772
chr11_-_900793 0.980 CHID1
chitinase domain containing 1
chr10_+_73393998 0.969 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr19_+_7505723 0.964 PNPLA6
patatin-like phospholipase domain containing 6
chr19_-_1827133 0.955


chr17_+_58058479 0.954 NM_006039
MRC2
mannose receptor, C type 2
chr13_+_112681626 0.954 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr8_-_145099963 0.953 NM_201379
PLEC
plectin
chr5_+_32747194 0.951 NM_000908
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr2_+_219354948 0.951 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr11_-_118799452 0.949 NM_006288
THY1
Thy-1 cell surface antigen
chrX_-_154341451 0.943 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr5_+_146594718 0.941 NM_001112724
NM_145001
STK32A

serine/threonine kinase 32A

chr14_-_68515761 0.935 ACTN1
actinin, alpha 1
chr7_+_28415495 0.935 LOC401317
hypothetical LOC401317
chr22_-_22970850 0.935 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chr7_+_2638108 0.933 NM_025250
TTYH3
tweety homolog 3 (Drosophila)
chr9_+_36126710 0.933 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr14_-_68515791 0.931 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr3_+_195888701 0.931 FAM43A
family with sequence similarity 43, member A
chr7_+_93861808 0.930 NM_000089
COL1A2
collagen, type I, alpha 2
chr3_+_171619346 0.927 NM_005602
CLDN11
claudin 11
chr2_+_241174803 0.925 NM_023083
NM_023085
CAPN10

calpain 10

chr8_-_38444398 0.924 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr8_-_38444675 0.924 FGFR1
fibroblast growth factor receptor 1
chr19_+_40322231 0.923 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_38376980 0.922 LRP3
low density lipoprotein receptor-related protein 3
chr11_-_86061003 0.919 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr7_-_78920806 0.913 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_+_102659464 0.909 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr19_-_20011251 0.908 NM_033196
ZNF682
zinc finger protein 682
chr14_+_76297885 0.906 NM_014909
VASH1
vasohibin 1
chr17_-_73867748 0.903 NM_003955
SOCS3
suppressor of cytokine signaling 3
chrX_+_66683075 0.903 AR
androgen receptor
chr14_-_68515701 0.899 ACTN1
actinin, alpha 1
chr5_+_175725050 0.896 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr14_-_23727826 0.894 IPO4
importin 4
chr20_+_61054539 0.893 SLC17A9
solute carrier family 17, member 9
chr2_+_109729176 0.892 NM_023016
ANKRD57
ankyrin repeat domain 57
chr14_-_38971049 0.891 FBXO33
F-box protein 33
chr12_-_107516022 0.889 NM_181724
TMEM119
transmembrane protein 119
chr9_-_116190038 0.889 AKNA
AT-hook transcription factor
chr16_+_66153810 0.887 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr20_-_49612745 0.887 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr12_-_47468985 0.887 NM_020983
ADCY6
adenylate cyclase 6
chr14_+_100362236 0.882 MEG3
maternally expressed 3 (non-protein coding)
chr2_-_101457596 0.880 NM_001145664
RFX8
regulatory factor X, 8
chr8_-_38444982 0.878 FGFR1
fibroblast growth factor receptor 1
chr19_-_9790682 0.875 NM_017703
FBXL12
F-box and leucine-rich repeat protein 12
chr2_+_200879737 0.873 SPATS2L
spermatogenesis associated, serine-rich 2-like
chr8_-_145132551 0.873 PARP10
poly (ADP-ribose) polymerase family, member 10
chr20_+_42417752 0.873 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr1_-_23758871 0.872 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr9_-_35062578 0.871 VCP
valosin containing protein
chrX_-_128485121 0.868 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr5_-_138758783 0.867 NM_001161546
LOC389333
hypothetical protein LOC389333
chr3_+_185514937 0.866 NM_001194946
NM_001194947
NM_198241
NM_198242
NM_198244
EIF4G1




eukaryotic translation initiation factor 4 gamma, 1




chr2_+_54536780 0.865 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_-_45562112 0.863 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr11_-_65395248 0.862 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr2_+_32435800 0.860 BIRC6
baculoviral IAP repeat containing 6
chr3_+_49034050 0.853 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 2.01e-08 GO:0065007 biological regulation
1.13 7.71e-08 GO:0050789 regulation of biological process
1.14 9.08e-08 GO:0050794 regulation of cellular process
1.35 1.73e-06 GO:0009966 regulation of signal transduction
1.28 4.98e-06 GO:0030154 cell differentiation
1.26 1.78e-05 GO:0048869 cellular developmental process
1.17 1.51e-04 GO:0032502 developmental process
1.28 1.54e-04 GO:0023051 regulation of signaling
1.25 3.54e-04 GO:0048583 regulation of response to stimulus
1.20 8.86e-04 GO:0048518 positive regulation of biological process
1.17 9.93e-04 GO:0007275 multicellular organismal development
1.17 1.07e-03 GO:0080090 regulation of primary metabolic process
1.22 1.67e-03 GO:0048523 negative regulation of cellular process
1.21 1.75e-03 GO:0048519 negative regulation of biological process
1.37 2.18e-03 GO:0051128 regulation of cellular component organization
1.42 2.46e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.15 2.51e-03 GO:0019222 regulation of metabolic process
1.35 2.93e-03 GO:0050793 regulation of developmental process
1.16 4.03e-03 GO:0060255 regulation of macromolecule metabolic process
1.16 4.98e-03 GO:0031323 regulation of cellular metabolic process
1.18 5.46e-03 GO:0048731 system development
1.59 6.24e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.19 7.59e-03 GO:0048522 positive regulation of cellular process
1.47 7.96e-03 GO:0072358 cardiovascular system development
1.47 7.96e-03 GO:0072359 circulatory system development
1.37 8.07e-03 GO:2000026 regulation of multicellular organismal development
1.25 1.09e-02 GO:0007399 nervous system development
1.16 2.10e-02 GO:0048856 anatomical structure development
1.18 2.33e-02 GO:0010468 regulation of gene expression
1.47 3.07e-02 GO:0040008 regulation of growth
1.42 3.20e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.17 3.29e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.31 4.30e-02 GO:0022008 neurogenesis
1.42 4.38e-02 GO:0000904 cell morphogenesis involved in differentiation
1.17 4.52e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63 4.53e-02 GO:0048011 nerve growth factor receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 7.24e-04 GO:0005737 cytoplasm
1.05 3.46e-03 GO:0005622 intracellular
1.05 1.70e-02 GO:0044424 intracellular part
1.67 4.79e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.06 1.88e-05 GO:0005488 binding
1.10 4.08e-04 GO:0005515 protein binding
1.13 7.74e-03 GO:0043167 ion binding
1.13 8.55e-03 GO:0046872 metal ion binding
1.13 1.19e-02 GO:0043169 cation binding
1.40 2.88e-02 GO:0030695 GTPase regulator activity
1.39 4.28e-02 GO:0060589 nucleoside-triphosphatase regulator activity