Motif ID: ZBTB16.p2

Z-value: 1.690


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB16chr11_+_113436438-0.175.3e-01Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_53444733 2.831 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr1_+_196874759 2.578 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_196874839 2.575 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_196874867 2.551 PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_-_40454360 2.498 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr13_-_45654292 2.389 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_161701711 2.232 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr9_+_263025 2.127 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr7_+_106293112 2.086 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_+_188197029 2.053


chr10_+_70517863 1.950 SRGN
serglycin
chr4_-_38460983 1.822 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr10_+_70517823 1.771 NM_002727
SRGN
serglycin
chr19_+_14554895 1.743 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr13_-_40454188 1.717 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_+_173111306 1.695 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr9_-_70780574 1.626


chr12_+_14429499 1.625 ATF7IP
activating transcription factor 7 interacting protein
chrX_-_153698930 1.577 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr21_-_14840506 1.548 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr13_-_98757634 1.547 NM_004951
GPR183
G protein-coupled receptor 183
chrX_+_134803450 1.515 NM_018666
SAGE1
sarcoma antigen 1
chr16_+_20682812 1.513 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr2_+_201833467 1.513 NM_033356
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr8_+_86287161 1.509 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chrX_-_23955223 1.507 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr12_-_51887318 1.471 ITGB7
integrin, beta 7
chr6_+_105511615 1.364 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr10_-_69267774 1.328 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr1_-_143708467 1.301 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr17_-_64462976 1.285 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr10_+_89257569 1.275 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr4_-_38710376 1.244 NM_024943
TMEM156
transmembrane protein 156
chr10_+_35466715 1.212 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr6_-_49820030 1.211 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr11_-_5110383 1.180 NM_001005160
OR52A5
olfactory receptor, family 52, subfamily A, member 5
chr12_-_51887266 1.154 NM_000889
ITGB7
integrin, beta 7
chr12_+_53178834 1.150 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr13_-_40491405 1.128 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_156923111 1.120 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_-_186752952 1.117 NM_139248
LIPH
lipase, member H
chr6_+_10629550 1.096 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_9777126 1.078 NM_172004
CLECL1
C-type lectin-like 1
chr13_-_48873735 1.059 NM_030925
CAB39L
calcium binding protein 39-like
chr7_-_142369519 1.030 KEL
Kell blood group, metallo-endopeptidase
chr12_+_25096755 1.021 LRMP
lymphoid-restricted membrane protein
chr11_-_73397929 1.019 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr4_+_22608252 0.997


chr8_+_39890484 0.992 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr4_+_970775 0.985 NM_000203
IDUA
iduronidase, alpha-L-
chr6_-_33149244 0.979 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr11_-_5212168 0.975 NM_000519
HBD
hemoglobin, delta
chr4_+_74825138 0.971 NM_000584
IL8
interleukin 8
chr2_+_24660849 0.969 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr19_-_21438525 0.969


chr7_-_142369534 0.966 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr5_-_88155360 0.964 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr10_-_31328426 0.962 NM_001143769
ZNF438
zinc finger protein 438
chr13_-_40491491 0.933 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_+_99733432 0.929 NM_005290
GPR15
G protein-coupled receptor 15
chr10_-_11614279 0.913 NM_001080491
USP6NL
USP6 N-terminal like
chr10_-_32707549 0.909 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_+_165565006 0.903 POU2F1
POU class 2 homeobox 1
chr2_+_170370290 0.894 SSB
Sjogren syndrome antigen B (autoantigen La)
chr15_+_89248423 0.892 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr1_+_154120170 0.882 SYT11
synaptotagmin XI
chr7_-_92693716 0.877 NM_001039372
HEPACAM2
HEPACAM family member 2
chr4_+_39874921 0.872 NM_004310
RHOH
ras homolog gene family, member H
chr4_-_145159889 0.839 NM_002100
GYPB
glycophorin B (MNS blood group)
chr13_-_45654296 0.839 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_123779122 0.822 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr17_+_63766874 0.817 NM_014960
ARSG
arylsulfatase G
chr21_+_29374743 0.810 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr19_+_3713650 0.805 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr2_+_38746555 0.804 NM_138801
GALM
galactose mutarotase (aldose 1-epimerase)
chr1_-_100003936 0.791 NM_001013660
FRRS1
ferric-chelate reductase 1
chr10_+_62208094 0.788 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr7_+_106292932 0.784 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr10_+_97505398 0.779 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr12_-_88573949 0.779 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr17_+_19917420 0.777 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr19_-_56612653 0.777 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr1_-_111544820 0.775 DENND2D
DENN/MADD domain containing 2D
chr16_+_10387412 0.773 ATF7IP2
activating transcription factor 7 interacting protein 2
chr1_-_180624494 0.773 GLUL
glutamate-ammonia ligase
chrX_+_12795111 0.763 NM_016562
TLR7
toll-like receptor 7
chr7_-_26202626 0.748 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr10_+_35524060 0.747 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr7_+_129634935 0.746 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr5_+_67622242 0.742 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr19_+_3713671 0.741 MRPL54
mitochondrial ribosomal protein L54
chr21_+_42697058 0.731 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr18_+_606671 0.730 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr5_+_171553780 0.730 NM_001171183
EFCAB9
EF-hand calcium binding domain 9
chr2_+_201755865 0.722 NM_001230
NM_032974
NM_032977
CASP10


caspase 10, apoptosis-related cysteine peptidase


chr5_-_75044001 0.722 NM_152408
POC5
POC5 centriolar protein homolog (Chlamydomonas)
chr5_-_78318112 0.722 NM_000046
ARSB
arylsulfatase B
chr1_+_114298021 0.714 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr3_-_17757402 0.713 NM_014744
TBC1D5
TBC1 domain family, member 5
chr21_-_38415273 0.710 NM_005867
DSCR4
Down syndrome critical region gene 4
chrX_-_23765377 0.701 RPL9
ribosomal protein L9
chr2_-_242205556 0.687 NM_001164356
THAP4
THAP domain containing 4
chr8_-_30704984 0.685 NM_000637
NM_001195102
NM_001195103
NM_001195104
GSR



glutathione reductase



chr4_+_123311207 0.679 NM_015312
KIAA1109
KIAA1109
chr6_-_33085329 0.679 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr10_-_42183441 0.673 LOC283027
hypothetical protein LOC283027
chr11_+_123600553 0.661 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr1_+_58899 0.661 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr7_-_149960218 0.658 GIMAP6
GTPase, IMAP family member 6
chr12_+_9713472 0.656 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr19_-_1601246 0.654 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr3_-_143230124 0.640 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr10_+_49279647 0.640 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr19_-_58016696 0.637 NM_006969
ZNF28
zinc finger protein 28
chr11_-_104332631 0.635 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr6_+_26212082 0.631 NM_003542
HIST1H4C
histone cluster 1, H4c
chr5_+_68703036 0.628 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr13_-_45654327 0.625 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_167969802 0.621 NM_000450
SELE
selectin E
chrX_-_78509662 0.613 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr15_+_89212888 0.613 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chrX_-_153903963 0.611 NM_000132
F8
coagulation factor VIII, procoagulant component
chr2_-_17563186 0.605 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr9_+_134843918 0.605 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr1_+_51340487 0.601 NM_001136508
C1orf185
chromosome 1 open reading frame 185
chr6_+_112775224 0.600 NM_001013734
RFPL4B
ret finger protein-like 4B
chr12_-_10464308 0.600 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr7_+_142670711 0.599 GSTK1
glutathione S-transferase kappa 1
chr2_-_157890400 0.595 NM_020711
ERMN
ermin, ERM-like protein
chr9_-_133602745 0.592 NM_005312
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr6_-_44341296 0.590 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_-_37916803 0.588 NM_152413
GOT1L1
glutamic-oxaloacetic transaminase 1-like 1
chr5_+_96237923 0.586 ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_-_32054164 0.579 NM_144569
SPOCD1
SPOC domain containing 1
chr5_-_10360873 0.577 CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr7_+_26298136 0.576 SNX10
sorting nexin 10
chr12_-_10453409 0.576 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr10_+_21924265 0.575 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr3_+_39484073 0.574 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr16_-_4464524 0.572 NMRAL1
NmrA-like family domain containing 1
chr12_-_69434650 0.570 PTPRR
protein tyrosine phosphatase, receptor type, R
chr16_+_88511787 0.570 NM_002386
MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr19_+_56990222 0.569 NM_002030
FPR3
formyl peptide receptor 3
chr11_+_59920062 0.567 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr19_+_61624 0.566 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr10_-_45350804 0.556 NM_001002266
MARCH8
membrane-associated ring finger (C3HC4) 8
chr6_+_167445284 0.554 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chrX_+_153310313 0.551 ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr7_+_99263571 0.549 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr4_-_145281237 0.548 NM_002099
GYPA
glycophorin A (MNS blood group)
chr6_-_44341222 0.545 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr11_-_5756472 0.534 NM_001001922
OR52N5
olfactory receptor, family 52, subfamily N, member 5
chr3_-_184756101 0.533 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr4_-_47709717 0.533 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr19_-_53450953 0.529 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr12_+_43972732 0.528 NM_001142678
ANO6
anoctamin 6
chr1_+_170894780 0.526 NM_000639
FASLG
Fas ligand (TNF superfamily, member 6)
chr19_-_44518516 0.524 NM_004877
GMFG
glia maturation factor, gamma
chr14_+_19761708 0.523 NM_001004480
OR11H6
olfactory receptor, family 11, subfamily H, member 6
chr1_+_239762179 0.521 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr11_+_63030099 0.520 NM_001142535
NM_001142536
NM_033101
LGALS12


lectin, galactoside-binding, soluble, 12


chr1_-_204455269 0.517 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr22_+_20880112 0.517


chr7_+_77307382 0.517 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chrX_+_48427137 0.516 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr22_-_34886727 0.510 NM_145640
APOL3
apolipoprotein L, 3
chr12_-_55432348 0.509 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr5_-_88235624 0.507 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr8_+_7340777 0.504 NM_001037668
NM_001040705
DEFB107A
DEFB107B
defensin, beta 107A
defensin, beta 107B
chr3_+_39346200 0.502 NM_005201
CCR8
chemokine (C-C motif) receptor 8
chr1_+_158975662 0.501 NM_021181
SLAMF7
SLAM family member 7
chr4_-_77176163 0.500 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chrX_-_23835868 0.500 NM_024122
APOO
apolipoprotein O
chr7_-_124357272 0.500 NM_001042594
NM_015450
POT1

protection of telomeres 1 homolog (S. pombe)

chr12_-_10479810 0.495 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr5_-_41107161 0.492 NM_173489
HEATR7B2
HEAT repeat family member 7B2
chr2_+_168383427 0.490 NM_020981
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_+_31791063 0.488 NM_021246
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr5_-_110090264 0.488 NM_001039763
TMEM232
transmembrane protein 232
chr6_+_147568795 0.488 STXBP5
syntaxin binding protein 5 (tomosyn)
chr22_-_40666168 0.488 NM_001110215
CENPM
centromere protein M
chr8_-_66863841 0.488 NM_002603
PDE7A
phosphodiesterase 7A
chr3_+_32968069 0.487 NM_005508
CCR4
chemokine (C-C motif) receptor 4
chr11_-_89181390 0.487 NM_020358
TRIM49
tripartite motif containing 49
chr1_+_76024466 0.485 NM_004582
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr16_-_45562840 0.484 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr2_-_231697999 0.481 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr1_+_100099353 0.480 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr2_-_234441739 0.480 MSL3L2
male-specific lethal 3-like 2 (Drosophila)
chr3_+_173954940 0.479 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chrX_+_48427103 0.479 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr11_+_63030131 0.478 LGALS12
lectin, galactoside-binding, soluble, 12
chr3_-_188339882 0.476 NM_052969
RPL39L
ribosomal protein L39-like
chr17_-_26672757 0.473 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr16_-_12805133 0.471 CPPED1
calcineurin-like phosphoesterase domain containing 1
chr2_-_207291364 0.471 NM_001093730
DYTN
dystrotelin
chrX_-_33056464 0.470 NM_004010
NM_004009
DMD

dystrophin

chr7_+_6583560 0.470 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr16_+_80370400 0.467 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr12_+_12829807 0.466 NM_030817
APOLD1
apolipoprotein L domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.34 2.42e-08 GO:0007608 sensory perception of smell
2.21 1.05e-07 GO:0007606 sensory perception of chemical stimulus
1.65 1.41e-03 GO:0007600 sensory perception
1.57 4.97e-02 GO:0006955 immune response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.38 4.86e-09 GO:0004984 olfactory receptor activity
1.77 1.69e-06 GO:0004930 G-protein coupled receptor activity
1.53 6.21e-05 GO:0004888 transmembrane receptor activity
1.44 1.46e-04 GO:0004872 receptor activity
1.32 7.98e-03 GO:0004871 signal transducer activity
1.32 7.98e-03 GO:0060089 molecular transducer activity
2.81 1.80e-02 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds