Motif ID: FEV.p2

Z-value: 2.732


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2195585170.411.2e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_61910318 4.772 NM_181506
LRRC70
leucine rich repeat containing 70
chr3_-_184756101 3.468 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr22_+_25398690 3.227 LOC388889
hypothetical LOC388889
chr3_-_122862391 3.198 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr5_-_88214720 3.182 MEF2C
myocyte enhancer factor 2C
chr3_-_122862447 3.146 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_+_120495906 3.102 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr12_-_56157898 3.048 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr21_-_38792173 2.864 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr21_-_14840506 2.776 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_+_39874921 2.756 NM_004310
RHOH
ras homolog gene family, member H
chr11_+_65164167 2.706 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr7_+_106292975 2.647 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292932 2.565 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr10_-_98021144 2.546 NM_001114094
NM_013314
BLNK

B-cell linker

chr13_+_110653407 2.518 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr2_-_175207521 2.367 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr17_-_31441390 2.344 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr6_-_32268267 2.323 GPSM3
G-protein signaling modulator 3
chr11_-_72111027 2.312 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr9_-_116190038 2.286 AKNA
AT-hook transcription factor
chrX_-_44945025 2.246 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr10_+_49562866 2.206 WDFY4
WDFY family member 4
chr4_-_101658094 2.197 NM_001159694
NM_016242
EMCN

endomucin

chr2_+_161701711 2.195 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr1_-_79244948 2.176 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr2_+_130846263 2.167 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr3_-_13032130 2.159


chr6_-_119137923 2.141 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr3_+_120799411 2.113 NM_015900
PLA1A
phospholipase A1 member A
chr12_-_6103945 2.066 NM_000552
VWF
von Willebrand factor
chr6_-_32268615 2.048 GPSM3
G-protein signaling modulator 3
chr2_-_225519974 2.028 DOCK10
dedicator of cytokinesis 10
chr15_+_79376295 1.988 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr1_+_111544469 1.970


chr1_-_111544603 1.955


chr6_+_153060722 1.950 NM_025107
MYCT1
myc target 1
chr7_+_106293112 1.914 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr22_+_35586950 1.913 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_-_31003260 1.898 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr5_-_54317102 1.860 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr19_-_6432765 1.851 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr1_-_205161821 1.816 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr19_+_16860807 1.809 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr5_+_40877053 1.808 NM_032587
CARD6
caspase recruitment domain family, member 6
chr7_-_3049872 1.804 NM_032415
CARD11
caspase recruitment domain family, member 11
chr3_-_150533948 1.777 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr3_+_120496180 1.768 ARHGAP31
Rho GTPase activating protein 31
chr13_-_27967215 1.752 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr3_+_114733907 1.736 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr21_+_25856311 1.710 MIR155HG
MIR155 host gene (non-protein coding)
chr19_-_44518465 1.704 GMFG
glia maturation factor, gamma
chr19_-_1083109 1.698 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr6_-_42527760 1.687 NM_033502
TRERF1
transcriptional regulating factor 1
chr17_-_16816113 1.670 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr19_+_16860871 1.644 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr17_-_40843530 1.643 ARHGAP27
Rho GTPase activating protein 27
chr4_+_91035025 1.633 NM_007351
MMRN1
multimerin 1
chr10_+_26767657 1.627 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr20_+_19818209 1.620 NM_018993
RIN2
Ras and Rab interactor 2
chr18_-_59137488 1.586 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr1_-_159306037 1.586 ARHGAP30
Rho GTPase activating protein 30
chr10_+_26767698 1.577 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr9_-_129656413 1.567 ENG
endoglin
chr1_+_111217244 1.559 NM_000560
CD53
CD53 molecule
chrX_-_50403412 1.552 SHROOM4
shroom family member 4
chr10_+_49563520 1.536 NM_020945
WDFY4
WDFY family member 4
chr1_+_111217314 1.532 CD53
CD53 molecule
chr14_+_20319049 1.531 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chrX_+_128741562 1.526 NM_018990
SASH3
SAM and SH3 domain containing 3
chr19_-_44518516 1.513 NM_004877
GMFG
glia maturation factor, gamma
chr22_-_35970133 1.493 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr13_-_32658215 1.488 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chrX_+_128741578 1.487 SASH3
SAM and SH3 domain containing 3
chr12_+_11694172 1.483 ETV6
ets variant 6
chr9_-_129656581 1.479 ENG
endoglin
chr1_-_205012348 1.472 NM_000572
IL10
interleukin 10
chr22_-_35970230 1.466 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr17_-_35975227 1.444 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr13_-_45654296 1.441 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_46224791 1.431 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr12_-_52939584 1.426 NM_001127322
CBX5
chromobox homolog 5
chr13_-_45654327 1.420 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_10311262 1.419 NM_002162
ICAM3
intercellular adhesion molecule 3
chr16_-_29664765 1.407 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr12_-_56159631 1.398 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr9_-_129656778 1.396 ENG
endoglin
chr6_-_11490487 1.382 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr11_+_65164767 1.380 SIPA1
signal-induced proliferation-associated 1
chr22_-_39189369 1.374 MKL1
megakaryoblastic leukemia (translocation) 1
chr1_-_159306210 1.370 ARHGAP30
Rho GTPase activating protein 30
chr13_-_45654292 1.360 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_159306273 1.350 ARHGAP30
Rho GTPase activating protein 30
chr11_-_76059435 1.350 NM_001128922
LRRC32
leucine rich repeat containing 32
chr12_+_12829807 1.341 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr10_-_88707299 1.339 NM_024756
MMRN2
multimerin 2
chr17_-_59451662 1.321 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr9_-_129656830 1.317 NM_000118
NM_001114753
ENG

endoglin

chr1_+_202000906 1.307 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr17_+_37694007 1.303 STAT5A
signal transducer and activator of transcription 5A
chr14_+_62740878 1.301 NM_020663
RHOJ
ras homolog gene family, member J
chr7_-_92615593 1.295 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr7_+_143683365 1.288 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_+_31650069 1.279 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr17_+_44642587 1.279 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr1_+_196874867 1.279 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_204797516 1.276 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr6_+_139391570 1.262 C6orf115
chromosome 6 open reading frame 115
chr12_-_15005761 1.261 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_111544784 1.250 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr17_-_43977273 1.245 NM_002145
HOXB2
homeobox B2
chr1_+_157067729 1.243 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr1_-_155788775 1.241 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr1_+_43539239 1.231 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chrX_+_12795111 1.226 NM_016562
TLR7
toll-like receptor 7
chr17_-_26672757 1.224 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr17_-_44642934 1.224 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_+_196874839 1.224 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_56159895 1.218 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr9_-_133141726 1.214 NM_033387
FAM78A
family with sequence similarity 78, member A
chr10_+_70517823 1.213 NM_002727
SRGN
serglycin
chr19_-_51820133 1.212 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr3_-_114176401 1.210 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr19_-_56567602 1.209 NM_005601
NKG7
natural killer cell group 7 sequence
chr14_-_37795290 1.204 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr3_+_47004457 1.202 NBEAL2
neurobeachin-like 2
chr2_+_33514896 1.199 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_+_63730720 1.198 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr1_-_158815850 1.196 CD84
CD84 molecule
chr11_-_110755112 1.193 POU2AF1
POU class 2 associating factor 1
chr4_-_10295412 1.192 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr17_-_40655347 1.179 LOC339192
hypothetical LOC339192
chr1_-_158815895 1.174 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr2_+_45732416 1.172 NM_005400
PRKCE
protein kinase C, epsilon
chr3_-_11585264 1.164 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr10_+_70517863 1.161 SRGN
serglycin
chr1_+_196874759 1.155 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr7_-_44985084 1.148 MYO1G
myosin IG
chr7_+_143028663 1.139 NM_173678
FAM115C
family with sequence similarity 115, member C
chr11_+_63730766 1.138 FERMT3
fermitin family member 3
chr11_+_63864263 1.136 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr8_+_42247991 1.131 NM_001190720
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr7_+_150044530 1.127 NM_130759
GIMAP1
GTPase, IMAP family member 1
chr16_-_30301357 1.122 SEPT1
septin 1
chr11_+_1830763 1.118 NM_002339
LSP1
lymphocyte-specific protein 1
chr16_+_29581783 1.115 NM_001030288
SPN
sialophorin
chr1_+_204797120 1.109 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr2_+_233633348 1.105 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr2_+_233633279 1.103 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr19_-_47328399 1.103 NM_002698
POU2F2
POU class 2 homeobox 2
chr12_+_74160779 1.089 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr8_+_42248008 1.084 NM_001190721
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr3_+_195889845 1.083 FAM43A
family with sequence similarity 43, member A
chr1_-_111544820 1.075 DENND2D
DENN/MADD domain containing 2D
chr2_+_173394560 1.075 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr22_+_36008511 1.073 CYTH4
cytohesin 4
chr8_+_42247954 1.071 NM_001190722
NM_001556
IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

chr11_-_3818713 1.068 RHOG
ras homolog gene family, member G (rho G)
chr1_+_159943385 1.067 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr7_-_44985175 1.065 MYO1G
myosin IG
chr16_-_49272617 1.062 SNX20
sorting nexin 20
chr1_+_204797079 1.061 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr13_-_42464301 1.059 NM_001002264
NM_033255
EPSTI1

epithelial stromal interaction 1 (breast)

chr11_-_3818759 1.053 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr1_-_149004879 1.044 CTSS
cathepsin S
chr2_+_177210683 1.041


chr4_-_153820535 1.038 NM_152680
TMEM154
transmembrane protein 154
chr12_-_52939636 1.038 NM_001127321
CBX5
chromobox homolog 5
chr16_-_49272741 1.030 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr6_+_139391511 1.030 NM_021243
C6orf115
chromosome 6 open reading frame 115
chr13_-_40454360 1.029 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr8_+_42247978 1.018 IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr7_+_149842850 1.015 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr1_+_170077234 1.010 NM_001136127
NM_015569
DNM3

dynamin 3

chr6_-_31658044 1.008 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr7_+_93388951 1.004 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr4_+_2783764 1.001 SH3BP2
SH3-domain binding protein 2
chr12_-_3732478 0.999 EFCAB4B
EF-hand calcium binding domain 4B
chr1_+_204797214 0.993 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr10_+_35524835 0.993 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr7_-_143523582 0.992 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr7_-_44985202 0.991 NM_033054
MYO1G
myosin IG
chr22_+_36008465 0.988 CYTH4
cytohesin 4
chr1_-_246869181 0.974 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr16_-_30301634 0.973 NM_052838
SEPT1
septin 1
chr12_+_50592379 0.973 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr11_-_110755366 0.968 NM_006235
POU2AF1
POU class 2 associating factor 1
chr10_+_129735796 0.965 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_-_31003181 0.963 LAPTM5
lysosomal protein transmembrane 5
chr14_-_93512818 0.962 ASB2
ankyrin repeat and SOCS box containing 2
chr5_-_176869943 0.958 NM_001144875
NM_001144876
DOK3

docking protein 3

chr4_+_2783743 0.953 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr7_+_69869099 0.953 AUTS2
autism susceptibility candidate 2
chr21_-_45165204 0.951 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr9_+_94766379 0.950 FGD3
FYVE, RhoGEF and PH domain containing 3
chr6_-_30760413 0.945 KIAA1949
KIAA1949
chr1_+_66570683 0.938 PDE4B
phosphodiesterase 4B, cAMP-specific
chr7_-_149960612 0.938 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr4_-_105631915 0.930 NM_025212
CXXC4
CXXC finger protein 4
chr22_+_36008369 0.928 NM_013385
CYTH4
cytohesin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.71 1.69e-11 GO:0001775 cell activation
1.88 5.35e-08 GO:0045321 leukocyte activation
1.18 1.39e-07 GO:0051716 cellular response to stimulus
1.46 5.94e-07 GO:0006955 immune response
1.35 9.25e-07 GO:0002376 immune system process
1.18 9.12e-06 GO:0007165 signal transduction
1.26 9.75e-06 GO:0048583 regulation of response to stimulus
1.56 1.12e-05 GO:0050776 regulation of immune response
1.15 1.19e-05 GO:0044260 cellular macromolecule metabolic process
1.84 2.92e-05 GO:0046649 lymphocyte activation
1.20 3.28e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 3.86e-05 GO:0090304 nucleic acid metabolic process
2.18 6.20e-05 GO:0050851 antigen receptor-mediated signaling pathway
1.10 8.79e-05 GO:0050794 regulation of cellular process
1.11 1.10e-04 GO:0050896 response to stimulus
1.81 1.58e-04 GO:0002764 immune response-regulating signaling pathway
1.09 1.84e-04 GO:0065007 biological regulation
1.70 1.90e-04 GO:0002694 regulation of leukocyte activation
1.80 1.96e-04 GO:0050867 positive regulation of cell activation
1.10 2.05e-04 GO:0050789 regulation of biological process
1.80 2.08e-04 GO:0002696 positive regulation of leukocyte activation
1.16 2.28e-04 GO:0023052 signaling
2.06 2.30e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.20 2.36e-04 GO:0006950 response to stress
1.83 2.61e-04 GO:0051251 positive regulation of lymphocyte activation
1.48 2.76e-04 GO:0007599 hemostasis
1.48 3.03e-04 GO:0007596 blood coagulation
1.48 3.03e-04 GO:0050817 coagulation
1.67 3.25e-04 GO:0050865 regulation of cell activation
1.70 3.85e-04 GO:0030168 platelet activation
1.06 4.50e-04 GO:0009987 cellular process
1.39 4.65e-04 GO:0002682 regulation of immune system process
1.49 6.54e-04 GO:0002684 positive regulation of immune system process
1.45 7.09e-04 GO:0006974 response to DNA damage stimulus
1.70 7.19e-04 GO:0051249 regulation of lymphocyte activation
1.78 7.40e-04 GO:0002757 immune response-activating signal transduction
2.03 9.92e-04 GO:0050670 regulation of lymphocyte proliferation
2.01 1.42e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.01 1.42e-03 GO:0032944 regulation of mononuclear cell proliferation
1.42 1.83e-03 GO:0050878 regulation of body fluid levels
1.80 2.91e-03 GO:0002697 regulation of immune effector process
1.32 3.05e-03 GO:0009611 response to wounding
2.58 3.57e-03 GO:0050871 positive regulation of B cell activation
1.95 4.00e-03 GO:0070663 regulation of leukocyte proliferation
2.12 5.68e-03 GO:0002699 positive regulation of immune effector process
2.12 5.68e-03 GO:0050852 T cell receptor signaling pathway
1.85 5.99e-03 GO:0002521 leukocyte differentiation
1.31 7.53e-03 GO:0006351 transcription, DNA-dependent
2.11 8.21e-03 GO:0050671 positive regulation of lymphocyte proliferation
1.95 1.19e-02 GO:0030098 lymphocyte differentiation
2.09 1.22e-02 GO:0032946 positive regulation of mononuclear cell proliferation
1.20 1.24e-02 GO:0006464 protein modification process
1.11 1.30e-02 GO:0043170 macromolecule metabolic process
2.55 1.33e-02 GO:0030888 regulation of B cell proliferation
1.37 1.51e-02 GO:0006259 DNA metabolic process
1.78 1.63e-02 GO:0050870 positive regulation of T cell activation
1.28 1.72e-02 GO:0032774 RNA biosynthetic process
2.08 1.76e-02 GO:0042113 B cell activation
2.06 1.79e-02 GO:0070665 positive regulation of leukocyte proliferation
1.19 2.11e-02 GO:0043412 macromolecule modification
1.56 2.52e-02 GO:0030036 actin cytoskeleton organization
1.39 2.80e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.67 2.85e-02 GO:0050863 regulation of T cell activation
1.59 3.25e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.51 3.44e-02 GO:0050778 positive regulation of immune response
1.22 4.98e-02 GO:0035556 intracellular signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 1.02e-05 GO:0031981 nuclear lumen
1.22 1.91e-05 GO:0044428 nuclear part
1.28 4.90e-05 GO:0005654 nucleoplasm
1.17 2.15e-03 GO:0043233 organelle lumen
1.10 3.48e-03 GO:0005634 nucleus
1.17 5.12e-03 GO:0031974 membrane-enclosed lumen
1.87 6.15e-03 GO:0005925 focal adhesion
1.17 7.03e-03 GO:0070013 intracellular organelle lumen
1.15 9.35e-03 GO:0043228 non-membrane-bounded organelle
1.15 9.35e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.17 1.68e-02 GO:0005829 cytosol
1.78 2.56e-02 GO:0005924 cell-substrate adherens junction
1.76 3.12e-02 GO:0030055 cell-substrate junction
1.02 3.69e-02 GO:0044464 cell part
1.02 3.87e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 1.44e-08 GO:0005515 protein binding
1.38 1.72e-02 GO:0030695 GTPase regulator activity
1.37 1.89e-02 GO:0060589 nucleoside-triphosphatase regulator activity