Motif ID: FEV.p2

Z-value: 2.732


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2195585170.411.2e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_61910318 4.772 NM_181506
 LRRC70
leucine rich repeat containing 70
chr3_-_184756101 3.468 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr22_+_25398690 3.227 LOC388889
hypothetical LOC388889
chr3_-_122862391 3.198 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr5_-_88214720 3.182 MEF2C
myocyte enhancer factor 2C
chr3_-_122862447 3.146 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_+_120495906 3.102 NM_020754
 ARHGAP31
Rho GTPase activating protein 31
chr12_-_56157898 3.048 NM_001080156
 ARHGAP9
Rho GTPase activating protein 9
chr21_-_38792173 2.864 NM_001136155
NM_182918
 ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr21_-_14840506 2.776 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_+_39874921 2.756 NM_004310
 RHOH
ras homolog gene family, member H
chr11_+_65164167 2.706 NM_153253
 SIPA1
signal-induced proliferation-associated 1
chr7_+_106292975 2.647 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292932 2.565 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr10_-_98021144 2.546 NM_001114094
NM_013314
 BLNK

B-cell linker

chr13_+_110653407 2.518 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr2_-_175207521 2.367 NM_003387
 WIPF1
WAS/WASL interacting protein family, member 1
chr17_-_31441390 2.344 NM_002983
 CCL3
chemokine (C-C motif) ligand 3
chr6_-_32268267 2.323 GPSM3
G-protein signaling modulator 3
chr11_-_72111027 2.312 NM_001135190
NM_015242
 ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 66 entries
enrichment   p-value GO term description
2.58 3.57e-03 GO:0050871 positive regulation of B cell activation
2.55 1.33e-02 GO:0030888 regulation of B cell proliferation
2.18 6.20e-05 GO:0050851 antigen receptor-mediated signaling pathway
2.12 5.68e-03 GO:0002699 positive regulation of immune effector process
2.12 5.68e-03 GO:0050852 T cell receptor signaling pathway
2.11 8.21e-03 GO:0050671 positive regulation of lymphocyte proliferation
2.09 1.22e-02 GO:0032946 positive regulation of mononuclear cell proliferation
2.08 1.76e-02 GO:0042113 B cell activation
2.06 2.30e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.06 1.79e-02 GO:0070665 positive regulation of leukocyte proliferation
2.03 9.92e-04 GO:0050670 regulation of lymphocyte proliferation
2.01 1.42e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.01 1.42e-03 GO:0032944 regulation of mononuclear cell proliferation
1.95 4.00e-03 GO:0070663 regulation of leukocyte proliferation
1.95 1.19e-02 GO:0030098 lymphocyte differentiation
1.88 5.35e-08 GO:0045321 leukocyte activation
1.85 5.99e-03 GO:0002521 leukocyte differentiation
1.84 2.92e-05 GO:0046649 lymphocyte activation
1.83 2.61e-04 GO:0051251 positive regulation of lymphocyte activation
1.81 1.58e-04 GO:0002764 immune response-regulating signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.87 6.15e-03 GO:0005925 focal adhesion
1.78 2.56e-02 GO:0005924 cell-substrate adherens junction
1.76 3.12e-02 GO:0030055 cell-substrate junction
1.28 4.90e-05 GO:0005654 nucleoplasm
1.24 1.02e-05 GO:0031981 nuclear lumen
1.22 1.91e-05 GO:0044428 nuclear part
1.17 2.15e-03 GO:0043233 organelle lumen
1.17 5.12e-03 GO:0031974 membrane-enclosed lumen
1.17 7.03e-03 GO:0070013 intracellular organelle lumen
1.17 1.68e-02 GO:0005829 cytosol
1.15 9.35e-03 GO:0043228 non-membrane-bounded organelle
1.15 9.35e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.10 3.48e-03 GO:0005634 nucleus
1.02 3.69e-02 GO:0044464 cell part
1.02 3.87e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.38 1.72e-02 GO:0030695 GTPase regulator activity
1.37 1.89e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.12 1.44e-08 GO:0005515 protein binding