Motif ID: HIF1A.p2

Z-value: 1.480


Transcription factors associated with HIF1A.p2:

Gene SymbolEntrez IDGene Name
HIF1A 3091 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HIF1Achr14_+_612317950.185.0e-01Click!


Activity profile for motif HIF1A.p2.

activity profile for motif HIF1A.p2


Sorted Z-values histogram for motif HIF1A.p2

Sorted Z-values for motif HIF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_38720881 2.033 NM_138435
 FAM83F
family with sequence similarity 83, member F
chr10_-_88720908 1.811 LOC100133190
hypothetical LOC100133190
chr13_-_43259032 1.798 NM_017993
 ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr1_+_231816372 1.409 NM_002245
 KCNK1
potassium channel, subfamily K, member 1
chr10_+_112247614 1.319 NM_004419
 DUSP5
dual specificity phosphatase 5
chr1_+_13899272 1.260 NM_001135610
 PRDM2
PR domain containing 2, with ZNF domain
chr3_-_180651874 1.231 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr11_+_20341835 1.224 NM_001098520
 HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr11_+_12088639 1.206 NM_014632
 MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr11_+_20341806 1.172 NM_006410
NM_001098521
 HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr11_+_20341900 1.126 NM_001098522
 HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr3_-_180652024 1.124 NM_021629
 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr4_+_321607 1.095 ZNF141
zinc finger protein 141
chr19_-_53516962 1.089 CCDC114
coiled-coil domain containing 114
chr4_+_321587 1.077 NM_003441
 ZNF141
zinc finger protein 141
chr6_+_73388713 1.054 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr1_+_231816540 1.052 KCNK1
potassium channel, subfamily K, member 1
chr11_+_94141151 0.985 NM_130847
 AMOTL1
angiomotin like 1
chr10_+_3099708 0.962 NM_002627
 PFKP
phosphofructokinase, platelet
chr6_+_33697023 0.956 NM_002224
 ITPR3
inositol 1,4,5-triphosphate receptor, type 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.45 1.35e-04 GO:0006913 nucleocytoplasmic transport
2.42 1.91e-04 GO:0051169 nuclear transport
1.58 2.37e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.30 4.54e-02 GO:0043412 macromolecule modification
1.22 5.35e-04 GO:0044260 cellular macromolecule metabolic process
1.15 1.32e-02 GO:0044237 cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.16 1.35e-02 GO:0031965 nuclear membrane
2.15 4.90e-05 GO:0005635 nuclear envelope
1.30 2.16e-03 GO:0005829 cytosol
1.28 6.07e-03 GO:0044428 nuclear part
1.21 9.77e-07 GO:0005634 nucleus
1.15 7.47e-08 GO:0043231 intracellular membrane-bounded organelle
1.15 1.00e-07 GO:0043227 membrane-bounded organelle
1.15 1.14e-03 GO:0044444 cytoplasmic part
1.14 2.12e-14 GO:0044424 intracellular part
1.14 4.84e-06 GO:0005737 cytoplasm
1.13 1.86e-13 GO:0005622 intracellular
1.13 4.03e-07 GO:0043226 organelle
1.13 6.43e-07 GO:0043229 intracellular organelle
1.05 1.91e-04 GO:0044464 cell part
1.05 1.98e-04 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.29 3.67e-02 GO:0016740 transferase activity
1.25 3.88e-02 GO:0000166 nucleotide binding
1.20 4.09e-02 GO:0003676 nucleic acid binding
1.13 3.23e-03 GO:0005515 protein binding
1.07 4.83e-03 GO:0005488 binding