Motif ID: ONECUT1,2.p2

Z-value: 2.085


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ONECUT2chr18_+_532537750.581.9e-02Click!
ONECUT1chr15_-_508693790.572.1e-02Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_30238961 10.154 NM_033229
TRIM15
tripartite motif containing 15
chr7_+_116238309 4.446 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr1_+_196874867 4.369 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_-_100077072 4.070 NM_003227
TFR2
transferrin receptor 2
chrX_-_24600661 3.769 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr6_-_41823056 3.294 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr6_+_32003180 3.138 NM_000063
NM_001145903
C2

complement component 2

chr17_+_69950782 3.046 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_+_196874839 3.021 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_611896 3.013 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_+_196874759 2.963 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_357502 2.880 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr11_+_62893836 2.670 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr3_-_150422474 2.655 NM_000096
CP
ceruloplasmin (ferroxidase)
chr5_+_180726874 2.637 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr5_+_68703036 2.557 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr6_+_105511615 2.549 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr18_-_28606839 2.464 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr1_-_51660328 2.460 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr8_-_107023 2.429 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr17_-_64462976 2.360 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr6_+_64344307 2.346 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_-_53849929 2.337 NM_017763
RNF43
ring finger protein 43
chr15_-_100280784 2.259 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr4_+_74491272 2.254 ALB
albumin
chr10_+_7785360 2.249 ITIH2
inter-alpha (globulin) inhibitor H2
chr14_+_87560646 2.244 LOC283587
hypothetical protein LOC283587
chr7_-_23476497 2.231 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr14_-_23090606 2.205 NM_033400
ZFHX2
zinc finger homeobox 2
chr10_+_7785347 2.166 ITIH2
inter-alpha (globulin) inhibitor H2
chr7_+_6583560 2.161 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr5_-_149772563 2.127 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_-_69852090 2.098 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr14_-_37134050 2.076 FOXA1
forkhead box A1
chr10_+_7785290 2.027 ITIH2
inter-alpha (globulin) inhibitor H2
chr13_-_45654292 1.978 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr10_+_7785235 1.962 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr2_+_130703384 1.960


chr5_+_68702617 1.955 NM_133340
NM_133341
RAD17

RAD17 homolog (S. pombe)

chrX_+_134803450 1.934 NM_018666
SAGE1
sarcoma antigen 1
chr5_-_149772528 1.917


chrX_+_46825179 1.897 RGN
regucalcin (senescence marker protein-30)
chr10_+_89257569 1.893 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr16_+_68156497 1.887 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NFAT5




nuclear factor of activated T-cells 5, tonicity-responsive




chr10_+_7785331 1.884 ITIH2
inter-alpha (globulin) inhibitor H2
chr13_-_45654296 1.870 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_17757402 1.858 NM_014744
TBC1D5
TBC1 domain family, member 5
chr3_-_198784590 1.818 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr19_-_9087438 1.810 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr1_-_198643885 1.806 ZNF281
zinc finger protein 281
chr6_+_132000134 1.789 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_-_145159889 1.757 NM_002100
GYPB
glycophorin B (MNS blood group)
chr22_+_21384862 1.741 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr2_+_132196533 1.739 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr6_+_28032997 1.721 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chrX_+_49718954 1.698 NM_000084
CLCN5
chloride channel 5
chr5_-_149772469 1.682 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr2_-_32344192 1.660 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr9_+_263025 1.648 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr13_-_45654327 1.644 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_99263571 1.631 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr2_-_88208650 1.624 NM_001443
FABP1
fatty acid binding protein 1, liver
chr2_+_113601608 1.606 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr14_-_37133927 1.578 FOXA1
forkhead box A1
chr2_+_113601616 1.562 IL1RN
interleukin 1 receptor antagonist
chr10_-_73953699 1.547 NM_001195519
CBARA1
calcium binding atopy-related autoantigen 1
chr18_+_27425727 1.542 NM_000371
TTR
transthyretin
chr7_+_120490054 1.532 C7orf58
chromosome 7 open reading frame 58
chr3_+_173043832 1.514 NM_001164436
TMEM212
transmembrane protein 212
chr4_+_22608252 1.501


chr3_+_144165470 1.500 U2SURP
U2 snRNP-associated SURP domain containing
chr20_-_33705244 1.482 NM_003915
CPNE1
copine I
chr12_+_53178834 1.477 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr14_-_22496196 1.467 HAUS4
HAUS augmin-like complex, subunit 4
chr16_+_68238460 1.467 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_22652957 1.466 GAS2
growth arrest-specific 2
chr4_-_155731288 1.443 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr7_-_13992351 1.426 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr11_+_22652894 1.399 NM_005256
GAS2
growth arrest-specific 2
chr16_-_68346299 1.384 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_+_161980865 1.347 NM_006593
TBR1
T-box, brain, 1
chr4_-_116254381 1.333 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr6_+_34312979 1.332 HMGA1
high mobility group AT-hook 1
chr16_-_11274952 1.312 NM_021247
PRM3
protamine 3
chr6_+_34312906 1.308 HMGA1
high mobility group AT-hook 1
chr14_-_23117614 1.298 JPH4
junctophilin 4
chr11_-_118055564 1.294 NM_007180
TREH
trehalase (brush-border membrane glycoprotein)
chr14_-_23117833 1.282 NM_001146028
NM_032452
JPH4

junctophilin 4

chr4_+_69716298 1.272 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr1_-_100003936 1.264 NM_001013660
FRRS1
ferric-chelate reductase 1
chr19_+_61624 1.260 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr6_+_69401660 1.255 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr6_+_32021831 1.253 CFB
complement factor B
chr17_-_5078773 1.240 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr2_-_61098867 1.217 NM_144709
PUS10
pseudouridylate synthase 10
chr14_-_22496098 1.209 NM_001166269
NM_001166270
NM_017815
HAUS4


HAUS augmin-like complex, subunit 4


chr1_+_111215343 1.206 NM_001040033
CD53
CD53 molecule
chr9_+_35663852 1.204 NM_001216
CA9
carbonic anhydrase IX
chr6_+_26609427 1.193 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chrX_+_110252960 1.150 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr3_+_171022403 1.146 NM_001080460
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr12_+_45896318 1.136 NM_138371
FAM113B
family with sequence similarity 113, member B
chr16_+_21152516 1.126 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr12_-_52975777 1.112 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr16_-_73708118 1.109 LDHD
lactate dehydrogenase D
chr7_-_135263737 1.090 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr1_-_149611768 1.085 NM_003944
SELENBP1
selenium binding protein 1
chr19_-_61876057 1.079 NM_001005850
ZNF835
zinc finger protein 835
chr16_-_20610078 1.071 NM_052956
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr3_-_49435114 1.070 NM_000481
NM_001164710
NM_001164711
NM_001164712
AMT



aminomethyltransferase



chr20_+_42417502 1.064 HNF4A
hepatocyte nuclear factor 4, alpha
chr3_-_49434874 1.055 AMT
aminomethyltransferase
chr16_-_73708165 1.054 NM_153486
NM_194436
LDHD

lactate dehydrogenase D

chr11_-_16953135 1.047 RPL36A
ribosomal protein L36a
chr18_+_31488530 1.021 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr19_-_55539769 1.016 NAPSB
napsin B aspartic peptidase pseudogene
chr7_+_128795280 1.015 AHCYL2
adenosylhomocysteinase-like 2
chr11_+_89624017 1.001


chr21_-_42608774 0.981 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr9_-_14076901 0.980 NFIB
nuclear factor I/B
chr17_+_38178999 0.979 VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr2_-_21106291 0.970 APOB
apolipoprotein B (including Ag(x) antigen)
chr19_+_3713671 0.962 MRPL54
mitochondrial ribosomal protein L54
chr9_-_139262009 0.953 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr12_+_111375382 0.937 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr12_-_101036407 0.932 NM_024057
NUP37
nucleoporin 37kDa
chr14_-_37134191 0.919 NM_004496
FOXA1
forkhead box A1
chr5_+_147754467 0.915 FBXO38
F-box protein 38
chr1_-_17638797 0.910 NM_018715
RCC2
regulator of chromosome condensation 2
chr1_+_40635058 0.906 NM_001198980
SMAP2
small ArfGAP2
chr1_-_26505653 0.899 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr9_-_115877104 0.896 AMBP
alpha-1-microglobulin/bikunin precursor
chr19_-_44518516 0.893 NM_004877
GMFG
glia maturation factor, gamma
chr14_+_66901237 0.892 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_-_180452096 0.892 NM_014407
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr4_+_74496660 0.889 ALB
albumin
chr7_-_25234582 0.882 NM_022150
NPVF
neuropeptide VF precursor
chr4_+_74496575 0.880 ALB
albumin
chr4_+_73123712 0.876 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr18_-_13905534 0.869 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr5_-_43448174 0.861 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr1_-_156923111 0.858 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr17_+_7682355 0.854


chr19_-_53081326 0.853 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr20_+_42417752 0.851 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr9_-_137992766 0.847 UBAC1
UBA domain containing 1
chr6_-_24827265 0.843 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr14_+_38719462 0.843 PNN
pinin, desmosome associated protein
chr12_-_52975823 0.843 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr13_-_45577144 0.841 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr7_+_128795178 0.840 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr9_-_122852356 0.825 NM_001735
C5
complement component 5
chr17_+_7180571 0.817 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr10_-_52315390 0.816 A1CF
APOBEC1 complementation factor
chr14_+_19513442 0.815 NM_001005486
OR4K15
olfactory receptor, family 4, subfamily K, member 15
chr2_+_172530120 0.810 HAT1
histone acetyltransferase 1
chr1_+_111544469 0.802


chr18_-_46068689 0.790 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr3_-_156876798 0.789 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr3_+_82117978 0.786


chr3_+_39484073 0.780 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr15_-_62460622 0.779 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr9_-_69729984 0.779 NM_001024916
NM_201453
CBWD5
CBWD3
COBW domain containing 5
COBW domain containing 3
chr19_+_3713650 0.774 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr14_-_23117268 0.774 JPH4
junctophilin 4
chr19_+_41177882 0.772 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr16_-_70591377 0.772 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr20_-_47963682 0.770 NM_001135773
SPATA2
spermatogenesis associated 2
chr2_-_88946767 0.763


chrX_-_54841397 0.759 NM_198510
ITIH5L
inter-alpha (globulin) inhibitor H5-like
chr4_+_187424336 0.744 F11
coagulation factor XI
chr20_+_186376 0.741 NM_207469
DEFB132
defensin, beta 132
chr6_+_74228331 0.740 MTO1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr6_+_100161370 0.739 NM_021620
PRDM13
PR domain containing 13
chr17_-_46479127 0.737 SPAG9
sperm associated antigen 9
chr8_-_30121741 0.728 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr3_-_57209319 0.724 NM_003865
HESX1
HESX homeobox 1
chr8_-_110411283 0.716 NM_001128211
NUDCD1
NudC domain containing 1
chr5_-_78317444 0.716 NM_198709
ARSB
arylsulfatase B
chr19_-_4289750 0.711 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr4_+_88939725 0.710 NM_004967
IBSP
integrin-binding sialoprotein
chr1_-_146076704 0.707 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr14_+_38653177 0.704 NM_001009182
NM_001009183
NM_003616
SIP1


survival of motor neuron protein interacting protein 1


chr3_-_172227461 0.698 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr2_+_143603368 0.697 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr6_-_167195647 0.697 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr20_+_31613800 0.693 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chrX_+_30143595 0.692 NM_002364
MAGEB2
melanoma antigen family B, 2
chr9_-_137992967 0.690 NM_016172
UBAC1
UBA domain containing 1
chr4_+_187424111 0.689 NM_000128
F11
coagulation factor XI
chr10_-_105100684 0.688 PCGF6
polycomb group ring finger 6
chr5_+_139856688 0.686 ANKHD1
ankyrin repeat and KH domain containing 1
chr2_-_169455167 0.681 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr8_+_92330691 0.681 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr6_-_49820030 0.681 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr6_+_45404031 0.675 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr5_+_176449156 0.675 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr2_+_143603439 0.673 ARHGAP15
Rho GTPase activating protein 15
chr19_+_40632456 0.669 NM_005306
FFAR2
free fatty acid receptor 2
chr1_+_117098579 0.663 NM_001767
CD2
CD2 molecule

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.68 6.91e-09 GO:0007608 sensory perception of smell
2.48 8.41e-08 GO:0007606 sensory perception of chemical stimulus
1.80 6.46e-04 GO:0007600 sensory perception
1.25 1.56e-03 GO:0032501 multicellular organismal process
1.45 2.37e-02 GO:0003008 system process
1.51 2.70e-02 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 9.41e-06 GO:0071944 cell periphery
1.32 1.18e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.76 7.27e-10 GO:0004984 olfactory receptor activity
2.06 1.57e-08 GO:0004930 G-protein coupled receptor activity
1.78 1.83e-07 GO:0004888 transmembrane receptor activity
1.65 2.48e-07 GO:0004872 receptor activity
1.51 9.81e-06 GO:0004871 signal transducer activity
1.51 9.81e-06 GO:0060089 molecular transducer activity
4.85 1.89e-03 GO:0043498 cell surface binding