Motif ID: RUNX1..3.p2

Z-value: 4.453


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX3chr1_-_251640610.821.1e-04Click!
RUNX1chr21_-_35181956-0.712.0e-03Click!
RUNX2chr6_+_45498262-0.361.7e-01Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_25164061 18.471 NM_001031680
RUNX3
runt-related transcription factor 3
chr1_-_114215768 10.886 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr1_+_204797516 9.648 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr21_-_35343331 9.504 RUNX1
runt-related transcription factor 1
chr9_-_129580732 8.668 NM_170600
SH2D3C
SH2 domain containing 3C
chr16_+_29582069 8.579 NM_003123
SPN
sialophorin
chr21_-_35343500 8.046 RUNX1
runt-related transcription factor 1
chr1_+_204797214 7.953 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr2_-_158008763 7.720 NM_004288
CYTIP
cytohesin 1 interacting protein
chr14_+_92188329 7.422 RIN3
Ras and Rab interactor 3
chr21_-_35343456 7.400 NM_001754
RUNX1
runt-related transcription factor 1
chr9_-_122728173 7.286 TRAF1
TNF receptor-associated factor 1
chr21_-_35343428 7.271 RUNX1
runt-related transcription factor 1
chr21_-_35343448 7.025 RUNX1
runt-related transcription factor 1
chr16_+_29582065 6.759 SPN
sialophorin
chr12_-_101396459 6.504 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_-_30505804 6.448 NM_025159
CXorf21
chromosome X open reading frame 21
chr11_-_66961709 6.320 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr21_-_35343065 6.194 RUNX1
runt-related transcription factor 1
chr6_-_41276901 6.126 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.02 9.03e-06 GO:0007608 sensory perception of smell
1.93 2.31e-05 GO:0007606 sensory perception of chemical stimulus
1.69 2.02e-02 GO:0001775 cell activation
1.58 5.69e-03 GO:0006955 immune response
1.52 1.05e-04 GO:0002376 immune system process
1.52 1.81e-02 GO:0007600 sensory perception
1.37 4.11e-03 GO:0003008 system process
1.21 1.71e-06 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
6.23 1.38e-02 GO:0005833 hemoglobin complex
1.22 5.40e-04 GO:0005886 plasma membrane
1.21 6.46e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.47 3.08e-02 GO:0003823 antigen binding
2.01 8.55e-06 GO:0004984 olfactory receptor activity
1.55 1.04e-03 GO:0004930 G-protein coupled receptor activity
1.50 3.42e-05 GO:0004888 transmembrane receptor activity
1.45 5.29e-06 GO:0004872 receptor activity
1.42 7.74e-07 GO:0004871 signal transducer activity
1.42 7.74e-07 GO:0060089 molecular transducer activity