Motif ID: CREB1.p2

Z-value: 1.348


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_208103068-0.253.5e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_10202947 1.481 NM_004230
 S1PR2
sphingosine-1-phosphate receptor 2
chr12_-_113328271 1.319 NM_181486
 TBX5
T-box 5
chr1_+_26368969 1.045 NM_015871
 ZNF593
zinc finger protein 593
chr17_+_56884560 0.955 TBX4
T-box 4
chr7_-_158314945 0.941 ESYT2
extended synaptotagmin-like protein 2
chr2_-_156897286 0.927 NM_006186
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr19_+_58750305 0.918 NM_001079907
 ZNF331
zinc finger protein 331
chr7_-_158314963 0.898 NM_020728
 ESYT2
extended synaptotagmin-like protein 2
chr17_-_13445942 0.748 NM_006042
 HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr1_+_231816372 0.744 NM_002245
 KCNK1
potassium channel, subfamily K, member 1
chr1_-_226712140 0.715 NM_033445
 HIST3H2A
histone cluster 3, H2a
chr12_+_46133 0.714 NM_001170738
 IQSEC3
IQ motif and Sec7 domain 3
chr1_+_226712430 0.712 NM_175055
 HIST3H2BB
histone cluster 3, H2bb
chr12_+_4253143 0.673 NM_001759
 CCND2
cyclin D2
chr1_-_15723363 0.631 NM_001229
NM_032996
 CASP9

caspase 9, apoptosis-related cysteine peptidase

chr7_-_44992729 0.614 C7orf40
chromosome 7 open reading frame 40
chr4_-_89837951 0.613 NM_153757
 NAP1L5
nucleosome assembly protein 1-like 5
chr6_+_35335456 0.582 NM_003427
 ZNF76
zinc finger protein 76
chr11_-_76862197 0.573 NM_001128620
NM_002576
 PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr16_+_87300385 0.565 NM_001012759
NM_001012762
 CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 61 entries
enrichment   p-value GO term description
3.10 6.97e-04 GO:0051028 mRNA transport
2.96 6.27e-04 GO:0006403 RNA localization
2.95 1.14e-03 GO:0050657 nucleic acid transport
2.95 1.14e-03 GO:0050658 RNA transport
2.95 1.14e-03 GO:0051236 establishment of RNA localization
2.88 8.08e-03 GO:0065004 protein-DNA complex assembly
2.79 3.70e-04 GO:0071103 DNA conformation change
2.73 2.12e-02 GO:0071824 protein-DNA complex subunit organization
2.64 6.95e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.61 1.89e-02 GO:0006323 DNA packaging
2.34 2.59e-03 GO:0009261 ribonucleotide catabolic process
2.34 3.50e-03 GO:0009203 ribonucleoside triphosphate catabolic process
2.34 3.50e-03 GO:0009207 purine ribonucleoside triphosphate catabolic process
2.33 3.94e-03 GO:0009146 purine nucleoside triphosphate catabolic process
2.30 5.57e-03 GO:0009143 nucleoside triphosphate catabolic process
2.30 5.57e-03 GO:0009154 purine ribonucleotide catabolic process
2.24 5.35e-03 GO:0006195 purine nucleotide catabolic process
2.18 1.02e-02 GO:0072523 purine-containing compound catabolic process
2.14 1.26e-02 GO:0009166 nucleotide catabolic process
2.10 1.25e-02 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
3.68 4.83e-02 GO:0000781 chromosome, telomeric region
1.93 9.17e-06 GO:0005694 chromosome
1.93 1.04e-04 GO:0044427 chromosomal part
1.76 3.17e-03 GO:0005730 nucleolus
1.75 3.14e-10 GO:0005654 nucleoplasm
1.70 3.81e-13 GO:0031981 nuclear lumen
1.66 1.47e-14 GO:0044428 nuclear part
1.58 1.64e-11 GO:0070013 intracellular organelle lumen
1.55 5.34e-11 GO:0031974 membrane-enclosed lumen
1.55 1.54e-10 GO:0043233 organelle lumen
1.55 3.81e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.53 4.70e-02 GO:0031967 organelle envelope
1.44 4.89e-02 GO:0005794 Golgi apparatus
1.37 1.30e-16 GO:0044446 intracellular organelle part
1.36 1.16e-15 GO:0044422 organelle part
1.36 6.71e-04 GO:0031090 organelle membrane
1.36 1.24e-03 GO:0005829 cytosol
1.35 1.38e-14 GO:0005634 nucleus
1.35 3.18e-02 GO:0012505 endomembrane system
1.30 3.47e-25 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.64 1.25e-03 GO:0016462 pyrophosphatase activity
1.63 1.48e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.62 1.75e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.62 2.91e-03 GO:0017111 nucleoside-triphosphatase activity
1.52 2.58e-02 GO:0003723 RNA binding
1.47 3.26e-04 GO:0005524 ATP binding
1.45 4.32e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.44 1.70e-06 GO:0000166 nucleotide binding
1.44 8.21e-04 GO:0032559 adenyl ribonucleotide binding
1.44 1.14e-03 GO:0030554 adenyl nucleotide binding
1.42 1.41e-04 GO:0032553 ribonucleotide binding
1.42 1.41e-04 GO:0032555 purine ribonucleotide binding
1.42 2.09e-04 GO:0017076 purine nucleotide binding
1.39 3.02e-03 GO:0016740 transferase activity
1.34 3.97e-06 GO:0003676 nucleic acid binding
1.29 3.11e-02 GO:0003677 DNA binding
1.24 8.61e-06 GO:0003824 catalytic activity
1.17 6.26e-05 GO:0005515 protein binding
1.09 4.06e-04 GO:0005488 binding