Motif ID: CREB1.p2

Z-value: 1.348


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_208103068-0.253.5e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_10202947 1.481 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr12_-_113328271 1.319 NM_181486
TBX5
T-box 5
chr1_+_26368969 1.045 NM_015871
ZNF593
zinc finger protein 593
chr17_+_56884560 0.955 TBX4
T-box 4
chr7_-_158314945 0.941 ESYT2
extended synaptotagmin-like protein 2
chr2_-_156897286 0.927 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr19_+_58750305 0.918 NM_001079907
ZNF331
zinc finger protein 331
chr7_-_158314963 0.898 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr17_-_13445942 0.748 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr1_+_231816372 0.744 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr1_-_226712140 0.715 NM_033445
HIST3H2A
histone cluster 3, H2a
chr12_+_46133 0.714 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr1_+_226712430 0.712 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr12_+_4253143 0.673 NM_001759
CCND2
cyclin D2
chr1_-_15723363 0.631 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr7_-_44992729 0.614 C7orf40
chromosome 7 open reading frame 40
chr4_-_89837951 0.613 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr6_+_35335456 0.582 NM_003427
ZNF76
zinc finger protein 76
chr11_-_76862197 0.573 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr16_+_87300385 0.565 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr1_-_15723279 0.560 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr17_+_33761234 0.551 NM_014598
SOCS7
suppressor of cytokine signaling 7
chrX_+_30581377 0.548 NM_000167
NM_001128127
NM_203391
GK


glycerol kinase


chr19_+_12763295 0.546 NM_002229
JUNB
jun B proto-oncogene
chr12_-_93377742 0.544 CCDC41
coiled-coil domain containing 41
chr20_+_51023159 0.541 TSHZ2
teashirt zinc finger homeobox 2
chr16_-_87300308 0.538 NM_178841
RNF166
ring finger protein 166
chr1_-_53566171 0.538 NM_001018054
NM_004631
NM_017522
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chrX_-_7855400 0.532 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr19_+_47593137 0.525


chr16_-_66251611 0.520 ACD
adrenocortical dysplasia homolog (mouse)
chr16_-_87300233 0.517 NM_001171815
RNF166
ring finger protein 166
chr9_-_89779180 0.516 CDK20
cyclin-dependent kinase 20
chr1_+_204875671 0.514 DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr1_-_15723305 0.502 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr6_-_29703725 0.498 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_+_12763285 0.496 JUNB
jun B proto-oncogene
chr17_-_76064842 0.491 NM_002522
NPTX1
neuronal pentraxin I
chr18_+_2561509 0.485 NM_006101
NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr5_+_132021763 0.481 NM_002188
IL13
interleukin 13
chr6_+_35335278 0.462 ZNF76
zinc finger protein 76
chr7_-_140270749 0.460 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chrX_-_7855764 0.453 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr9_+_101623957 0.446 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr11_-_66367279 0.442


chr19_-_40938251 0.438 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr5_+_43157398 0.437 NM_003432
ZNF131
zinc finger protein 131
chr12_-_93377584 0.435 CCDC41
coiled-coil domain containing 41
chr19_-_6432765 0.434 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr11_-_68537243 0.432 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr1_-_1274618 0.428 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr2_+_46623396 0.419 RHOQ
ras homolog gene family, member Q
chr19_+_10388448 0.418 PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_204875374 0.417 NM_001004023
NM_003582
DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

chr14_-_102045749 0.416 ANKRD9
ankyrin repeat domain 9
chr11_-_3775547 0.415 NM_005387
NM_016320
NM_139131
NM_139132
NUP98



nucleoporin 98kDa



chr11_-_124871258 0.413 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr19_-_40938046 0.412 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr6_-_30631481 0.405 GNL1
guanine nucleotide binding protein-like 1
chr19_+_50663089 0.397 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr3_-_49041764 0.395 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr15_-_72513053 0.395 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr1_+_32443822 0.393 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr2_+_227408914 0.389 NM_001167608
NM_032276
RHBDD1

rhomboid domain containing 1

chr7_+_116447499 0.386 ST7
suppression of tumorigenicity 7
chr3_-_49041862 0.386 NM_000884
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr4_-_104338924 0.382 NM_001813
CENPE
centromere protein E, 312kDa
chr18_+_2561587 0.380 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_-_49041817 0.380 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr17_-_74348447 0.379 NM_025090
USP36
ubiquitin specific peptidase 36
chr12_-_131194794 0.378 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr5_+_131920455 0.378 NM_005732
RAD50
RAD50 homolog (S. cerevisiae)
chr18_-_2561422 0.378 NM_022840
METTL4
methyltransferase like 4
chr12_-_93377827 0.375 NM_001042399
NM_016122
CCDC41

coiled-coil domain containing 41

chr4_+_72271218 0.375 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr17_+_7151653 0.373 EIF5A
eukaryotic translation initiation factor 5A
chr17_+_7151984 0.372 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr5_+_137829065 0.368 EGR1
early growth response 1
chr6_+_15357013 0.367 JARID2
jumonji, AT rich interactive domain 2
chr3_+_158026769 0.367 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr1_+_141560298 0.367


chr11_+_359723 0.364 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr15_+_38843535 0.364 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr2_+_74914742 0.363 HK2
hexokinase 2
chr11_+_3775529 0.362 NM_001145438
PGAP2
post-GPI attachment to proteins 2
chr11_-_67029349 0.362 NM_001130848
NM_004910
PITPNM1

phosphatidylinositol transfer protein, membrane-associated 1

chr7_+_151353707 0.360 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr6_-_15356865 0.359


chr3_-_59010797 0.358 C3orf67
chromosome 3 open reading frame 67
chr19_-_54618410 0.356 NM_178449
PTH2
parathyroid hormone 2
chr7_+_151353759 0.350 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr3_-_59010777 0.350 C3orf67
chromosome 3 open reading frame 67
chr18_+_2836979 0.349 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr9_-_139202855 0.348 NM_013366
ANAPC2
anaphase promoting complex subunit 2
chr6_+_56927882 0.345 BEND6
BEN domain containing 6
chr17_-_39556535 0.344 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr9_+_124066973 0.342 MRRF
mitochondrial ribosome recycling factor
chr15_-_49817090 0.340 LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr14_+_69148062 0.340 NM_014734
KIAA0247
KIAA0247
chr6_+_35335212 0.339 ZNF76
zinc finger protein 76
chr19_+_13124870 0.337 IER2
immediate early response 2
chr14_-_103058568 0.335 CKB
creatine kinase, brain
chr5_+_49998528 0.334 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr19_+_13124889 0.333 IER2
immediate early response 2
chr5_+_78567604 0.332 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_+_87566738 0.332 NM_006769
LMO4
LIM domain only 4
chr5_+_139534874 0.332 C5orf32
chromosome 5 open reading frame 32
chr19_-_40939756 0.330 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr16_+_66252296 0.329 NM_001037281
NM_016948
PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans)

chr7_+_5598964 0.327 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr3_-_59010740 0.326 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr19_-_60320592 0.326 NM_017607
PPP1R12C
protein phosphatase 1, regulatory (inhibitor) subunit 12C
chr9_+_132990760 0.323 NM_005085
NUP214
nucleoporin 214kDa
chr14_+_69148066 0.321 KIAA0247
KIAA0247
chr7_+_127015650 0.318 NM_001662
ARF5
ADP-ribosylation factor 5
chr3_+_42952855 0.317 KRBOX1
KRAB box domain containing 1
chr20_+_32610161 0.316 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr18_+_55718171 0.314 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr16_+_1979959 0.311 NM_004209
SYNGR3
synaptogyrin 3
chr17_-_4831644 0.309 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chrX_-_13745134 0.309 GPM6B
glycoprotein M6B
chr6_-_49712483 0.309 NM_000324
RHAG
Rh-associated glycoprotein
chr5_-_139760838 0.307


chr7_+_151353775 0.306 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr2_+_46623325 0.306 NM_012249
RHOQ
ras homolog gene family, member Q
chr11_+_18372682 0.306 LDHA
lactate dehydrogenase A
chr1_-_53566331 0.305 NM_033300
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr18_+_22060383 0.305 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr2_+_219852268 0.304 NM_001039550
NM_006736
DNAJB2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr2_-_75280121 0.304 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr15_+_39739864 0.304 NM_001080541
NM_001164273
MGA

MAX gene associated

chr1_+_149309703 0.303 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr4_+_153676857 0.302 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr2_-_73373956 0.302 NM_001965
EGR4
early growth response 4
chr8_-_66916830 0.300 PDE7A
phosphodiesterase 7A
chr9_+_132990834 0.300 NUP214
nucleoporin 214kDa
chr15_-_99609648 0.300 NM_014918
CHSY1
chondroitin sulfate synthase 1
chrX_-_101284026 0.300 NM_001006938
TCEAL6
transcription elongation factor A (SII)-like 6
chr17_-_77442658 0.299 THOC4
THO complex 4
chr6_-_34772565 0.298 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr1_-_154665807 0.298 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr11_+_18372687 0.295 LDHA
lactate dehydrogenase A
chr12_-_121946581 0.293 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr4_-_170770111 0.292 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr11_+_18372689 0.291 LDHA
lactate dehydrogenase A
chr17_-_39556483 0.288 HDAC5
histone deacetylase 5
chr19_+_40183169 0.288 GRAMD1A
GRAM domain containing 1A
chr13_+_113287048 0.287 NM_007111
TFDP1
transcription factor Dp-1
chr9_-_124066901 0.287 NM_033117
RBM18
RNA binding motif protein 18
chr11_+_66367458 0.287 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr12_-_56111054 0.286 R3HDM2
R3H domain containing 2
chr19_-_17047228 0.286 NM_001011699
NM_033417
HAUS8

HAUS augmin-like complex, subunit 8

chr16_-_65516919 0.286 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr11_+_18372493 0.285 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr16_-_66252103 0.284 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr9_+_139202874 0.284 NM_003731
SSNA1
Sjogren syndrome nuclear autoantigen 1
chr11_+_110978309 0.283 NM_015191
SIK2
salt-inducible kinase 2
chrX_-_13745108 0.283 GPM6B
glycoprotein M6B
chr11_+_117362272 0.282 NM_001558
IL10RA
interleukin 10 receptor, alpha
chr3_-_199171234 0.281 NM_032263
IQCG
IQ motif containing G
chr15_+_39739933 0.281 MGA
MAX gene associated
chr6_-_30631912 0.280 GNL1
guanine nucleotide binding protein-like 1
chr6_-_136913235 0.278 MAP7
microtubule-associated protein 7
chr8_-_82186832 0.276 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr1_+_27591738 0.275 NM_005281
GPR3
G protein-coupled receptor 3
chr4_+_75699652 0.275 NM_001657
AREG
amphiregulin
chr1_-_159413833 0.275 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr1_+_87567164 0.275 LMO4
LIM domain only 4
chr7_+_150356435 0.274 NM_007188
ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr11_+_18372708 0.272 LDHA
lactate dehydrogenase A
chr1_+_87567136 0.272 LMO4
LIM domain only 4
chr8_-_22606653 0.269 NM_004430
EGR3
early growth response 3
chr11_-_119504726 0.268 TRIM29
tripartite motif containing 29
chr11_-_67028415 0.268 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr3_+_186786655 0.267 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr6_-_31778825 0.266 NM_001177515
ABHD16A
abhydrolase domain containing 16A
chr19_-_60610971 0.265 UBE2S
ubiquitin-conjugating enzyme E2S
chr6_+_30402986 0.264 NM_172016
TRIM39
tripartite motif containing 39
chr3_+_199171467 0.264 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr16_+_29915003 0.264 NM_173618
INO80E
INO80 complex subunit E
chr2_-_65513138 0.264 NM_181784
SPRED2
sprouty-related, EVH1 domain containing 2
chr16_+_29915063 0.263 INO80E
INO80 complex subunit E
chr11_+_68208583 0.262 GAL
galanin prepropeptide
chr20_+_33667160 0.262 NM_003116
SPAG4
sperm associated antigen 4
chr6_-_27222556 0.262 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr16_-_1999760 0.260 NM_178167
ZNF598
zinc finger protein 598
chr16_-_1999796 0.259 ZNF598
zinc finger protein 598
chr17_+_54997667 0.258 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr19_-_40728230 0.256


chr16_-_3707450 0.255 NM_016292
TRAP1
TNF receptor-associated protein 1
chr6_-_34772495 0.254 C6orf106
chromosome 6 open reading frame 106
chr14_-_102045849 0.253 NM_152326
ANKRD9
ankyrin repeat domain 9
chrX_-_44087778 0.253 NM_025184
EFHC2
EF-hand domain (C-terminal) containing 2
chrX_-_13745234 0.253 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr2_+_74610751 0.252 HTRA2
HtrA serine peptidase 2
chr17_+_7151368 0.252 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chr9_-_124066838 0.250 RBM18
RNA binding motif protein 18
chrX_+_7075820 0.249 STS
steroid sulfatase (microsomal), isozyme S
chr17_-_4831388 0.248 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr22_+_18485145 0.247 RANBP1
RAN binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 4.56e-12 GO:0044237 cellular metabolic process
1.54 1.41e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 6.79e-11 GO:0034641 cellular nitrogen compound metabolic process
1.46 2.76e-10 GO:0006807 nitrogen compound metabolic process
1.24 4.54e-09 GO:0008152 metabolic process
1.35 4.83e-09 GO:0044260 cellular macromolecule metabolic process
1.26 1.86e-08 GO:0044238 primary metabolic process
1.51 1.83e-07 GO:0090304 nucleic acid metabolic process
1.28 3.03e-06 GO:0043170 macromolecule metabolic process
1.51 2.74e-05 GO:0016070 RNA metabolic process
1.89 4.08e-05 GO:0006396 RNA processing
1.48 5.45e-05 GO:0010467 gene expression
1.50 1.33e-04 GO:0006996 organelle organization
2.79 3.70e-04 GO:0071103 DNA conformation change
1.11 6.04e-04 GO:0009987 cellular process
2.96 6.27e-04 GO:0006403 RNA localization
3.10 6.97e-04 GO:0051028 mRNA transport
1.71 7.80e-04 GO:0046907 intracellular transport
1.97 9.94e-04 GO:0000279 M phase
2.95 1.14e-03 GO:0050657 nucleic acid transport
2.95 1.14e-03 GO:0050658 RNA transport
2.95 1.14e-03 GO:0051236 establishment of RNA localization
2.34 2.59e-03 GO:0009261 ribonucleotide catabolic process
1.98 3.17e-03 GO:0006397 mRNA processing
1.35 3.24e-03 GO:0044249 cellular biosynthetic process
2.34 3.50e-03 GO:0009203 ribonucleoside triphosphate catabolic process
2.34 3.50e-03 GO:0009207 purine ribonucleoside triphosphate catabolic process
2.33 3.94e-03 GO:0009146 purine nucleoside triphosphate catabolic process
1.64 5.10e-03 GO:0022402 cell cycle process
2.24 5.35e-03 GO:0006195 purine nucleotide catabolic process
1.56 5.52e-03 GO:0007049 cell cycle
2.30 5.57e-03 GO:0009143 nucleoside triphosphate catabolic process
2.30 5.57e-03 GO:0009154 purine ribonucleotide catabolic process
2.04 5.87e-03 GO:0009259 ribonucleotide metabolic process
1.74 6.25e-03 GO:0051276 chromosome organization
1.69 6.54e-03 GO:0022403 cell cycle phase
2.08 6.79e-03 GO:0000087 M phase of mitotic cell cycle
2.64 6.95e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.88 8.08e-03 GO:0065004 protein-DNA complex assembly
2.18 1.02e-02 GO:0072523 purine-containing compound catabolic process
2.02 1.16e-02 GO:0009150 purine ribonucleotide metabolic process
2.10 1.25e-02 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
2.10 1.25e-02 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
2.14 1.26e-02 GO:0009166 nucleotide catabolic process
1.40 1.48e-02 GO:0034645 cellular macromolecule biosynthetic process
1.76 1.79e-02 GO:0016071 mRNA metabolic process
2.04 1.79e-02 GO:0000280 nuclear division
2.04 1.79e-02 GO:0007067 mitosis
1.90 1.80e-02 GO:0006163 purine nucleotide metabolic process
1.40 1.89e-02 GO:0009059 macromolecule biosynthetic process
2.61 1.89e-02 GO:0006323 DNA packaging
1.72 1.97e-02 GO:0000278 mitotic cell cycle
2.73 2.12e-02 GO:0071824 protein-DNA complex subunit organization
1.49 2.12e-02 GO:0044248 cellular catabolic process
1.31 2.30e-02 GO:0009058 biosynthetic process
1.77 2.36e-02 GO:0006753 nucleoside phosphate metabolic process
1.77 2.36e-02 GO:0009117 nucleotide metabolic process
1.73 3.25e-02 GO:0044282 small molecule catabolic process
1.98 4.00e-02 GO:0046700 heterocycle catabolic process
1.98 4.00e-02 GO:0048285 organelle fission
1.97 4.36e-02 GO:0009141 nucleoside triphosphate metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 3.47e-25 GO:0043231 intracellular membrane-bounded organelle
1.30 5.33e-25 GO:0043227 membrane-bounded organelle
1.20 5.70e-21 GO:0044424 intracellular part
1.18 4.46e-19 GO:0005622 intracellular
1.23 4.73e-19 GO:0043229 intracellular organelle
1.23 9.17e-19 GO:0043226 organelle
1.37 1.30e-16 GO:0044446 intracellular organelle part
1.36 1.16e-15 GO:0044422 organelle part
1.35 1.38e-14 GO:0005634 nucleus
1.66 1.47e-14 GO:0044428 nuclear part
1.70 3.81e-13 GO:0031981 nuclear lumen
1.58 1.64e-11 GO:0070013 intracellular organelle lumen
1.55 5.34e-11 GO:0031974 membrane-enclosed lumen
1.55 1.54e-10 GO:0043233 organelle lumen
1.75 3.14e-10 GO:0005654 nucleoplasm
1.20 2.50e-09 GO:0005737 cytoplasm
1.24 4.21e-07 GO:0044444 cytoplasmic part
1.93 9.17e-06 GO:0005694 chromosome
1.93 1.04e-04 GO:0044427 chromosomal part
1.28 2.79e-04 GO:0032991 macromolecular complex
1.36 6.71e-04 GO:0031090 organelle membrane
1.36 1.24e-03 GO:0005829 cytosol
1.76 3.17e-03 GO:0005730 nucleolus
1.05 6.11e-03 GO:0044464 cell part
1.05 6.28e-03 GO:0005623 cell
1.26 1.12e-02 GO:0043234 protein complex
1.35 3.18e-02 GO:0012505 endomembrane system
1.25 3.47e-02 GO:0043228 non-membrane-bounded organelle
1.25 3.47e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.55 3.81e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.53 4.70e-02 GO:0031967 organelle envelope
3.68 4.83e-02 GO:0000781 chromosome, telomeric region
1.44 4.89e-02 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.44 1.70e-06 GO:0000166 nucleotide binding
1.34 3.97e-06 GO:0003676 nucleic acid binding
1.24 8.61e-06 GO:0003824 catalytic activity
1.45 4.32e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.17 6.26e-05 GO:0005515 protein binding
1.42 1.41e-04 GO:0032553 ribonucleotide binding
1.42 1.41e-04 GO:0032555 purine ribonucleotide binding
1.42 2.09e-04 GO:0017076 purine nucleotide binding
1.47 3.26e-04 GO:0005524 ATP binding
1.09 4.06e-04 GO:0005488 binding
1.44 8.21e-04 GO:0032559 adenyl ribonucleotide binding
1.44 1.14e-03 GO:0030554 adenyl nucleotide binding
1.64 1.25e-03 GO:0016462 pyrophosphatase activity
1.63 1.48e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.62 1.75e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.62 2.91e-03 GO:0017111 nucleoside-triphosphatase activity
1.39 3.02e-03 GO:0016740 transferase activity
1.52 2.58e-02 GO:0003723 RNA binding
1.29 3.11e-02 GO:0003677 DNA binding