Motif ID: BPTF.p2

Z-value: 1.865


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BPTFchr17_+_633385000.495.3e-02Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_29297806 4.922 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr12_+_52696908 4.177 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr7_-_80386258 3.278 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_+_28692122 3.215 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr7_-_80386602 3.052 NM_006379
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_116749382 2.501 TRPS1
trichorhinophalangeal syndrome I
chr4_+_106851415 2.443 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr14_-_60818263 2.366 NM_001017970
TMEM30B
transmembrane protein 30B
chr12_-_41269679 2.164 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr12_-_84754289 1.989 NM_005447
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr9_+_5500544 1.975 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr5_+_108111421 1.948 NM_005246
FER
fer (fps/fes related) tyrosine kinase
chr20_+_51023159 1.934 TSHZ2
teashirt zinc finger homeobox 2
chr3_+_190990142 1.905 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr1_+_221955876 1.884 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr9_+_74956614 1.880 ANXA1
annexin A1
chr3_-_197549588 1.794 TM4SF19
transmembrane 4 L six family member 19
chr9_+_102231616 1.757 NM_001198806
C9orf30
chromosome 9 open reading frame 30
chr8_-_122722674 1.716 NM_005328
HAS2
hyaluronan synthase 2
chr17_-_35911340 1.639 NM_032865
TNS4
tensin 4
chr14_-_60817946 1.595


chr4_+_77829634 1.561 SHROOM3
shroom family member 3
chr1_-_17180659 1.537 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr5_-_59100194 1.528 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_81743198 1.497 BNC1
basonuclin 1
chr1_+_101475149 1.466 S1PR1
sphingosine-1-phosphate receptor 1
chr18_-_51406841 1.446 NM_001083962
NM_003199
TCF4

transcription factor 4

chr12_-_10718157 1.436 NM_018423
STYK1
serine/threonine/tyrosine kinase 1
chr1_+_181421796 1.408 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chrX_-_23955223 1.394 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr12_+_45759634 1.394 FAM113B
family with sequence similarity 113, member B
chr12_-_27126721 1.391 NM_001080406
C12orf71
chromosome 12 open reading frame 71
chr12_-_83830710 1.358 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr12_+_55201854 1.341 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr13_-_98428244 1.300 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr19_+_39860398 1.273 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr19_+_3087026 1.256 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr3_-_191322919 1.202 NM_001134418
LEPREL1
leprecan-like 1
chr18_+_27281729 1.197 NM_001944
DSG3
desmoglein 3
chr14_-_22722658 1.182 SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr7_+_75892187 1.169 NM_001110354
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr9_-_116608113 1.162 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr16_+_4485859 1.162 NM_001127205
HMOX2
heme oxygenase (decycling) 2
chrX_-_71709622 1.143 NM_001166418
NM_001166419
NM_001166420
NM_001166422
NM_001166448
NM_018486
HDAC8





histone deacetylase 8





chr18_+_19826734 1.125 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr4_+_26194643 1.117 NM_018317
TBC1D19
TBC1 domain family, member 19
chr16_+_3499894 1.113 NM_024793
CLUAP1
clusterin associated protein 1
chr20_-_17487480 1.104 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr7_+_18515440 1.102 HDAC9
histone deacetylase 9
chr3_-_197549640 1.094 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr1_-_197173159 1.094 LOC100131234
familial acute myelogenous leukemia related factor
chr12_-_83830700 1.090 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr12_-_83830670 1.074 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr9_+_74956601 1.073 ANXA1
annexin A1
chr5_-_16561936 1.072 NM_019000
FAM134B
family with sequence similarity 134, member B
chr18_-_20105814 1.040 OSBPL1A
oxysterol binding protein-like 1A
chr1_+_39569396 1.038 NM_033044
MACF1
microtubule-actin crosslinking factor 1
chr18_+_50646616 1.025 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr10_-_29963906 1.009 NM_021738
SVIL
supervillin
chr11_+_27019084 1.005 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_137224266 0.995 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr5_-_94442941 0.993 MCTP1
multiple C2 domains, transmembrane 1
chr7_-_87687276 0.973 SRI
sorcin
chr11_-_58099884 0.969 NM_004811
LPXN
leupaxin
chr19_+_62972808 0.950 NM_017652
ZNF586
zinc finger protein 586
chr12_-_84754112 0.946 RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr6_+_121798443 0.939 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr19_-_54005916 0.934 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr12_+_29193399 0.930 FAR2
fatty acyl CoA reductase 2
chr17_-_30799874 0.927 NM_144682
SLFN13
schlafen family member 13
chr9_+_74956494 0.923 NM_000700
ANXA1
annexin A1
chr13_-_32757835 0.909 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_52697160 0.909 HOXC5
HOXC6
homeobox C5
homeobox C6
chr5_+_55182963 0.892 NM_139017
IL31RA
interleukin 31 receptor A
chr9_-_36266930 0.884 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr12_-_41163680 0.880 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr2_-_85494639 0.879 CAPG
capping protein (actin filament), gelsolin-like
chr2_-_85494664 0.860 CAPG
capping protein (actin filament), gelsolin-like
chr7_+_143683365 0.860 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_+_84540921 0.858 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr1_-_45224853 0.845 NM_001166588
NM_020365
EIF2B3

eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

chr4_+_75449720 0.844 NM_001432
EREG
epiregulin
chrX_-_1291526 0.843 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr17_-_15495534 0.843 TRIM16
tripartite motif containing 16
chr15_+_65205107 0.833 NM_001145102
SMAD3
SMAD family member 3
chr1_-_159275334 0.832 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr10_-_29963847 0.827


chr1_+_13782838 0.826 NM_006474
NM_198389
PDPN

podoplanin

chr5_-_142045770 0.808 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr9_-_14303509 0.807 NFIB
nuclear factor I/B
chrX_+_119176494 0.802 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr21_-_38415273 0.799 NM_005867
DSCR4
Down syndrome critical region gene 4
chr1_-_68288899 0.790 NM_004675
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr4_+_155884564 0.790 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr18_-_20105900 0.789 OSBPL1A
oxysterol binding protein-like 1A
chr7_-_112513379 0.781 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr2_-_151052391 0.773 NM_005168
RND3
Rho family GTPase 3
chr19_+_62972861 0.768 ZNF586
zinc finger protein 586
chr11_+_113671744 0.763 NM_006169
NNMT
nicotinamide N-methyltransferase
chr15_-_41904059 0.752 NM_005926
MFAP1
microfibrillar-associated protein 1
chr19_-_52427698 0.748 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr15_+_47249700 0.748 NM_002044
GALK2
galactokinase 2
chr10_-_93992982 0.747 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr7_+_134226727 0.742 CALD1
caldesmon 1
chr1_-_45224784 0.740 EIF2B3
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chr2_-_162808123 0.736 NM_004460
FAP
fibroblast activation protein, alpha
chr5_+_36644187 0.733 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_+_79829794 0.732 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr14_+_101345878 0.731 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr3_-_33734544 0.731 CLASP2
cytoplasmic linker associated protein 2
chr10_-_32707549 0.717 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr5_-_158567411 0.706 NM_144726
RNF145
ring finger protein 145
chr10_+_91077581 0.702 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_+_36777406 0.695 VIT
vitrin
chr22_+_34443863 0.688 NM_030642
APOL5
apolipoprotein L, 5
chr18_+_3437607 0.673 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr6_+_47774247 0.672 NM_153838
GPR115
G protein-coupled receptor 115
chr8_+_67568044 0.672 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr11_+_93394025 0.663 NM_001098672
HEPHL1
hephaestin-like 1
chr1_-_17638797 0.660 NM_018715
RCC2
regulator of chromosome condensation 2
chr19_-_51319769 0.658 NM_207393
IGFL3
IGF-like family member 3
chr18_+_59405513 0.656 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_23393808 0.652 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr6_-_136913649 0.649 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr1_-_159275357 0.646 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr5_+_96237399 0.644 NM_001130140
NM_022350
ERAP2

endoplasmic reticulum aminopeptidase 2

chr14_-_49543987 0.641 NM_001012706
C14orf182
chromosome 14 open reading frame 182
chr7_-_87687302 0.640 NM_003130
SRI
sorcin
chr8_-_71743973 0.640 NM_016027
LACTB2
lactamase, beta 2
chr11_+_113672378 0.638 NNMT
nicotinamide N-methyltransferase
chr15_-_70288071 0.635 PKM2
pyruvate kinase, muscle
chr7_+_18515488 0.635 HDAC9
histone deacetylase 9
chr17_+_1580504 0.634 WDR81
WD repeat domain 81
chrX_-_138552517 0.632 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr15_+_92642433 0.623 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr2_-_113310796 0.621 NM_000576
IL1B
interleukin 1, beta
chr11_+_113672407 0.621 NNMT
nicotinamide N-methyltransferase
chr12_+_119224506 0.616 NM_012240
SIRT4
sirtuin 4
chr1_-_24311212 0.614 NM_152372
MYOM3
myomesin family, member 3
chr1_-_6502655 0.612 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr10_-_1061797 0.605 NM_033261
IDI2
isopentenyl-diphosphate delta isomerase 2
chr5_-_58607673 0.603 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_16811131 0.600 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr12_-_55432348 0.599 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr12_+_54796640 0.597 NM_001035267
NM_021104
RPL41

ribosomal protein L41

chr21_+_29439768 0.596 C21orf7
chromosome 21 open reading frame 7
chr12_+_7809078 0.589 NM_001145465
NANOGNB
NANOG neighbor homeobox
chr22_+_29974368 0.587 LIMK2
LIM domain kinase 2
chr1_+_24522116 0.586 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr21_+_29322100 0.585 USP16
ubiquitin specific peptidase 16
chr2_+_130846263 0.579 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr18_-_26876622 0.578 NM_001941
NM_024423
DSC3

desmocollin 3

chr1_-_42738535 0.575 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr1_+_141560298 0.572


chr11_-_47502115 0.570 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr19_-_48976852 0.570 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_+_82803248 0.569 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr12_+_19173669 0.568 NM_001143821
NM_001190860
NM_019012
PLEKHA5


pleckstrin homology domain containing, family A member 5


chr5_-_168660293 0.564 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr4_+_170817787 0.562 CLCN3
chloride channel 3
chr1_-_201202956 0.561 NM_016243
CYB5R1
cytochrome b5 reductase 1
chr19_-_19175064 0.560 NM_176880
NR2C2AP
nuclear receptor 2C2-associated protein
chr8_-_37847095 0.558 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr6_-_29563657 0.556 NM_052967
MAS1L
MAS1 oncogene-like
chr2_+_166034402 0.555 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_+_55276278 0.555 RPL41P5
ribosomal protein L41 pseudogene 5
chr19_-_2036227 0.555 MOBKL2A
MOB1, Mps One Binder kinase activator-like 2A (yeast)
chr1_-_6368324 0.553 NM_181864
ACOT7
acyl-CoA thioesterase 7
chr12_-_93921586 0.553 NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr6_+_147568795 0.545 STXBP5
syntaxin binding protein 5 (tomosyn)
chr5_+_53787187 0.541 NM_006308
HSPB3
heat shock 27kDa protein 3
chr6_-_32892705 0.541 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr5_+_159781454 0.539 PTTG1
pituitary tumor-transforming 1
chr22_-_34564611 0.539 RPL41P5
ribosomal protein L41 pseudogene 5
chr12_-_93921618 0.536 NM_018838
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr11_-_127962662 0.535 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr3_+_161040439 0.534 SCHIP1
schwannomin interacting protein 1
chr12_-_53314891 0.534 NM_033277
LACRT
lacritin
chr7_-_97457286 0.533 NM_006188
OCM2
oncomodulin 2
chr22_+_29974314 0.533 NM_001031801
NM_016733
LIMK2

LIM domain kinase 2

chr16_+_70117523 0.533 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr2_+_85515428 0.532 NM_198482
SH2D6
SH2 domain containing 6
chr19_-_14750347 0.532 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr8_-_72436519 0.530 EYA1
eyes absent homolog 1 (Drosophila)
chr18_+_7936885 0.525 PTPRM
protein tyrosine phosphatase, receptor type, M
chr2_+_73911477 0.525 STAMBP
STAM binding protein
chr1_+_218768146 0.522 MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_+_208067890 0.520 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr1_+_147819626 0.520 NM_178230
NM_001135789
PPIAL4A
PPIAL4G
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4G
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr10_-_126839000 0.519 CTBP2
C-terminal binding protein 2
chr16_+_32660135 0.516 LOC100289574
hect domain and RLD 2 pseudogene
chr19_+_43847049 0.514


chr2_+_169637255 0.514 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr19_+_12996368 0.512 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_-_48977247 0.510 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr9_+_124602190 0.510 NM_080859
OR1K1
olfactory receptor, family 1, subfamily K, member 1
chr14_-_98807574 0.509 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr7_+_12595672 0.509 NM_033128
SCIN
scinderin
chr15_+_87588188 0.504 NM_001113378
NM_018193
FANCI

Fanconi anemia, complementation group I

chr19_-_58016696 0.504 NM_006969
ZNF28
zinc finger protein 28

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 1.00e-02 GO:0044428 nuclear part
1.11 1.56e-02 GO:0005634 nucleus

Nothing significant found in function category.