Motif ID: POU2F1..3.p2

Z-value: 2.568


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1654565720.837.7e-05Click!
POU2F2chr19_-_473283990.457.7e-02Click!
POU2F3chr11_+_119616112-0.322.3e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_23754997 7.138 PRKCB
protein kinase C, beta
chr16_+_23754860 6.966 PRKCB
protein kinase C, beta
chr16_+_23754822 6.817 PRKCB
protein kinase C, beta
chr7_+_50318801 6.331 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr16_+_23754772 6.219 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chrX_-_48661226 4.851 NM_006875
PIM2
pim-2 oncogene
chr1_+_226712430 4.850 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr1_-_153098811 4.687 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_226712140 4.330 NM_033445
HIST3H2A
histone cluster 3, H2a
chr6_-_33016561 4.179 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_+_165565006 4.021 POU2F1
POU class 2 homeobox 1
chr19_-_17377383 4.018 NM_004335
BST2
bone marrow stromal cell antigen 2
chr19_+_17377502 4.006 LOC100507535
hypothetical LOC100507535
chr6_+_26359805 3.990 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr3_+_99733432 3.919 NM_005290
GPR15
G protein-coupled receptor 15
chr6_-_27968906 3.903 NM_003514
HIST1H2AM
histone cluster 1, H2am
chr6_+_26325124 3.898 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr1_+_165564904 3.793 NM_001198783
POU2F1
POU class 2 homeobox 1
chr10_-_98021144 3.584 NM_001114094
NM_013314
BLNK

B-cell linker

chr6_+_34312667 3.551 HMGA1
high mobility group AT-hook 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
9.66 3.41e-15 GO:0006334 nucleosome assembly
9.16 1.36e-14 GO:0031497 chromatin assembly
9.07 3.96e-15 GO:0034728 nucleosome organization
8.73 1.11e-14 GO:0065004 protein-DNA complex assembly
8.58 4.07e-15 GO:0071824 protein-DNA complex subunit organization
7.34 7.92e-14 GO:0006333 chromatin assembly or disassembly
7.02 1.18e-11 GO:0006323 DNA packaging
6.68 2.77e-02 GO:0050909 sensory perception of taste
6.27 5.71e-11 GO:0071103 DNA conformation change
3.48 4.61e-07 GO:0034622 cellular macromolecular complex assembly
3.17 9.52e-08 GO:0034621 cellular macromolecular complex subunit organization
3.07 1.29e-06 GO:0006325 chromatin organization
2.61 4.20e-07 GO:0006955 immune response
2.49 1.50e-04 GO:0051276 chromosome organization
2.25 1.37e-03 GO:0065003 macromolecular complex assembly
2.23 2.86e-04 GO:0006952 defense response
2.17 5.67e-04 GO:0043933 macromolecular complex subunit organization
2.11 6.85e-03 GO:0071844 cellular component assembly at cellular level
1.95 3.08e-04 GO:0002376 immune system process
1.52 5.23e-03 GO:0071842 cellular component organization at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
13.33 3.04e-18 GO:0000786 nucleosome
8.52 2.38e-13 GO:0032993 protein-DNA complex
4.94 1.01e-11 GO:0000785 chromatin
2.68 4.23e-05 GO:0044427 chromosomal part
2.59 1.20e-05 GO:0005694 chromosome
1.41 1.95e-02 GO:0043228 non-membrane-bounded organelle
1.41 1.95e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
9.88 2.01e-06 GO:0003823 antigen binding
1.77 2.52e-02 GO:0001071 nucleic acid binding transcription factor activity
1.77 2.52e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 1.16e-03 GO:0003677 DNA binding
1.52 1.04e-02 GO:0004871 signal transducer activity
1.52 1.04e-02 GO:0060089 molecular transducer activity