Motif ID: ELF1,2,4.p2

Z-value: 2.226


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_404543600.757.8e-04Click!
ELF2chr4_-_140317686-0.552.7e-02Click!
ELF4chrX_-_1290721030.116.7e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_110653407 2.656 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr5_+_61910318 2.133 NM_181506
LRRC70
leucine rich repeat containing 70
chr3_-_184756101 2.093 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr5_-_124108672 2.087 NM_020747
ZNF608
zinc finger protein 608
chr17_-_18890963 2.001 NM_006613
GRAP
GRB2-related adaptor protein
chr7_+_150044530 1.947 NM_130759
GIMAP1
GTPase, IMAP family member 1
chr22_+_25398690 1.808 LOC388889
hypothetical LOC388889
chr15_-_90999606 1.667 NM_207446
FAM174B
family with sequence similarity 174, member B
chr3_+_120495906 1.658 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr8_-_29262240 1.648 NM_057158
DUSP4
dual specificity phosphatase 4
chr1_-_159306037 1.607 ARHGAP30
Rho GTPase activating protein 30
chr17_-_59451662 1.567 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr9_+_115303527 1.545 NM_130795
RGS3
regulator of G-protein signaling 3
chr19_+_3129735 1.513 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr16_+_66129481 1.463 FAM65A
family with sequence similarity 65, member A
chr14_+_62740878 1.438 NM_020663
RHOJ
ras homolog gene family, member J
chr14_+_60858151 1.400 NM_006255
PRKCH
protein kinase C, eta
chr21_+_25856311 1.397 MIR155HG
MIR155 host gene (non-protein coding)
chr3_+_195889845 1.386 FAM43A
family with sequence similarity 43, member A
chr11_+_128069165 1.344 FLI1
Friend leukemia virus integration 1
chr1_-_159306273 1.342 ARHGAP30
Rho GTPase activating protein 30
chr1_-_159306210 1.329 ARHGAP30
Rho GTPase activating protein 30
chr11_+_128069183 1.324 FLI1
Friend leukemia virus integration 1
chr11_+_128068982 1.319 NM_002017
FLI1
Friend leukemia virus integration 1
chr4_+_91035025 1.315 NM_007351
MMRN1
multimerin 1
chr7_+_149842850 1.313 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr11_+_128069203 1.283 FLI1
Friend leukemia virus integration 1
chr9_-_116190038 1.278 AKNA
AT-hook transcription factor
chr14_+_75058591 1.249 BATF
basic leucine zipper transcription factor, ATF-like
chr16_-_3567354 1.248 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr14_-_37795001 1.243 CLEC14A
C-type lectin domain family 14, member A
chr14_+_75058518 1.239 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr12_-_3732614 1.222 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr12_-_6668880 1.189 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr2_-_175255717 1.185 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_11490487 1.180 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr3_+_120799411 1.169 NM_015900
PLA1A
phospholipase A1 member A
chr14_-_37795290 1.164 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr11_-_72111027 1.162 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr15_+_79376295 1.151 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr10_+_8137356 1.140 GATA3
GATA binding protein 3
chr3_+_120496180 1.137 ARHGAP31
Rho GTPase activating protein 31
chr11_+_128069340 1.130 FLI1
Friend leukemia virus integration 1
chr12_-_6668680 1.121 ZNF384
zinc finger protein 384
chr1_-_31003181 1.103 LAPTM5
lysosomal protein transmembrane 5
chrX_+_15428820 1.098 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr1_-_31003260 1.069 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr9_-_133141726 1.065 NM_033387
FAM78A
family with sequence similarity 78, member A
chr1_+_32489426 1.063 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr3_+_29297806 1.033 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr9_-_122731263 1.029 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr16_+_48865521 1.028 ADCY7
adenylate cyclase 7
chrX_-_50403412 1.023 SHROOM4
shroom family member 4
chr12_-_6668787 1.021 NM_001039918
NM_133476
ZNF384

zinc finger protein 384

chr1_+_182040837 0.990 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr3_-_122862447 0.988 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_26358097 0.986 NM_024869
GRRP1
glycine/arginine rich protein 1
chr3_-_122862391 0.983 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_50335113 0.962 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr12_+_11694172 0.948 ETV6
ets variant 6
chr11_+_107304344 0.948 NM_017516
RAB39
RAB39, member RAS oncogene family
chr7_-_3049872 0.937 NM_032415
CARD11
caspase recruitment domain family, member 11
chr3_-_120878910 0.936 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr1_-_224993498 0.934 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chrX_-_10504852 0.912 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr6_-_56824672 0.911 DST
dystonin
chr17_-_40843530 0.905 ARHGAP27
Rho GTPase activating protein 27
chr8_-_11096257 0.903 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr17_-_44010543 0.902 NM_024015
HOXB4
homeobox B4
chr12_+_11693993 0.893 NM_001987
ETV6
ets variant 6
chr12_-_3732478 0.891 EFCAB4B
EF-hand calcium binding domain 4B
chr17_-_74244539 0.880


chr4_+_2783743 0.878 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr1_-_111548440 0.858 DENND2D
DENN/MADD domain containing 2D
chr4_-_153820535 0.852 NM_152680
TMEM154
transmembrane protein 154
chr16_-_28843955 0.849 NM_024816
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr2_+_237143118 0.840 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr7_+_93388951 0.840 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr17_-_60208083 0.837 LOC146880
hypothetical LOC146880
chr11_+_1830763 0.832 NM_002339
LSP1
lymphocyte-specific protein 1
chr17_-_59817456 0.832 PECAM1
platelet/endothelial cell adhesion molecule
chr12_-_6103945 0.831 NM_000552
VWF
von Willebrand factor
chr12_+_11693909 0.822 ETV6
ets variant 6
chr10_-_116434364 0.820 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr3_-_172660545 0.820 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr6_-_42527760 0.799 NM_033502
TRERF1
transcriptional regulating factor 1
chr2_-_197883569 0.788 ANKRD44
ankyrin repeat domain 44
chr19_+_39860398 0.788 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr17_-_59817575 0.785 PECAM1
platelet/endothelial cell adhesion molecule
chr1_-_23376860 0.783 LUZP1
leucine zipper protein 1
chr8_-_6407882 0.780 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr1_-_159306327 0.774 ARHGAP30
Rho GTPase activating protein 30
chr12_+_36996823 0.774 NM_001013620
ALG10B
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)
chr19_-_53935648 0.762 NM_017805
RASIP1
Ras interacting protein 1
chr9_-_94472363 0.758 NM_022755
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr10_+_31650069 0.757 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr1_-_21478571 0.754 NM_001113347
ECE1
endothelin converting enzyme 1
chr16_-_21739231 0.753 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chr17_-_59817654 0.743 PECAM1
platelet/endothelial cell adhesion molecule
chr21_+_42807052 0.743 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr17_-_59817722 0.740 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr1_+_84382575 0.734 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr18_-_51219880 0.731 TCF4
transcription factor 4
chr1_+_84382562 0.730 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_19998955 0.729 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr12_+_120840829 0.728 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr22_-_36212160 0.728 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr16_+_28993770 0.722 RRN3P2
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
chrX_+_114734074 0.711 NM_001136025
NM_001172335
PLS3

plastin 3

chr2_-_197883703 0.710 ANKRD44
ankyrin repeat domain 44
chr1_+_84382529 0.706 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_94472090 0.705 IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr10_+_49562866 0.705 WDFY4
WDFY family member 4
chr2_-_242205556 0.695 NM_001164356
THAP4
THAP domain containing 4
chr11_-_407324 0.694 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr17_-_19821727 0.694 AKAP10
A kinase (PRKA) anchor protein 10
chr13_-_30089509 0.693 HMGB1
high-mobility group box 1
chr19_-_19615369 0.681 GMIP
GEM interacting protein
chr16_+_30102426 0.668 CORO1A
coronin, actin binding protein, 1A
chr22_-_42539399 0.666 NM_022785
NM_198856
EFCAB6

EF-hand calcium binding domain 6

chr3_+_99733432 0.663 NM_005290
GPR15
G protein-coupled receptor 15
chr9_-_21325239 0.662 NM_018847
KLHL9
kelch-like 9 (Drosophila)
chrX_-_128616594 0.660 NM_017413
APLN
apelin
chr10_+_75174125 0.660 NM_004922
NM_198597
SEC24C

SEC24 family, member C (S. cerevisiae)

chr16_-_49272617 0.659 SNX20
sorting nexin 20
chr9_-_133574928 0.659 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr19_-_19615452 0.658 NM_016573
GMIP
GEM interacting protein
chr2_-_128138435 0.655 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr22_+_36334811 0.649 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr19_+_10242763 0.647 ICAM1
intercellular adhesion molecule 1
chr12_+_95112131 0.643 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr20_-_1321744 0.642 NM_000801
NM_054014
FKBP1A

FK506 binding protein 1A, 12kDa

chr1_+_15955719 0.642 FBLIM1
filamin binding LIM protein 1
chr17_-_59818033 0.642 PECAM1
platelet/endothelial cell adhesion molecule
chr4_-_99283323 0.641 NM_174952
C4orf37
chromosome 4 open reading frame 37
chr20_+_19815075 0.641 RIN2
Ras and Rab interactor 2
chr1_+_35104120 0.635


chr19_-_39859997 0.627


chr6_-_166502119 0.625 NM_003181
T
T, brachyury homolog (mouse)
chr10_+_75174151 0.623 SEC24C
SEC24 family, member C (S. cerevisiae)
chr16_-_29664765 0.622 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr1_+_155130146 0.617 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr19_-_17819773 0.613 JAK3
Janus kinase 3
chrX_+_95826507 0.612 DIAPH2
diaphanous homolog 2 (Drosophila)
chr7_+_73145481 0.606 LIMK1
LIM domain kinase 1
chr10_-_27570998 0.603 ACBD5
acyl-CoA binding domain containing 5
chr9_-_129656413 0.602 ENG
endoglin
chr3_+_120781045 0.601 ADPRH
ADP-ribosylarginine hydrolase
chr10_+_129735796 0.600 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_-_116434102 0.599 ABLIM1
actin binding LIM protein 1
chr19_+_47073029 0.599 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr19_+_47593137 0.599


chr2_-_37752731 0.595 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr13_+_30089829 0.593 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr10_-_112668892 0.593 NM_001195304
NM_001195305
NM_001195307
BBIP1


BBSome interacting protein 1


chr11_+_122258600 0.593 NM_024806
NM_199124
C11orf63

chromosome 11 open reading frame 63

chr19_-_17819814 0.589 NM_000215
JAK3
Janus kinase 3
chr2_-_73817935 0.588 NM_016058
TPRKB
TP53RK binding protein
chr4_-_647974 0.588 PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr12_-_56157898 0.586 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr1_-_159306369 0.584 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr17_-_19821583 0.583 NM_007202
AKAP10
A kinase (PRKA) anchor protein 10
chr1_+_202000906 0.581 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr10_+_44816278 0.581 NM_006963
ZNF22
zinc finger protein 22 (KOX 15)
chr16_+_66236559 0.580 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr3_+_9826643 0.578 NM_001025930
TTLL3
tubulin tyrosine ligase-like family, member 3
chr11_-_117628211 0.577 NM_198275
MPZL3
myelin protein zero-like 3
chr21_-_38792173 0.576 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr22_+_36334622 0.574 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr9_-_129656581 0.573 ENG
endoglin
chr17_-_3814334 0.567 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr5_-_171547700 0.566 STK10
serine/threonine kinase 10
chrX_+_64804318 0.565 MSN
moesin
chr6_-_46997579 0.564 NM_001098518
GPR116
G protein-coupled receptor 116
chr5_-_138822475 0.560 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr9_-_35744271 0.554 NM_001044264
MSMP
microseminoprotein, prostate associated
chr19_-_4510713 0.554 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr2_-_197883739 0.554 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr2_-_207738858 0.551 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_-_53493198 0.550 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chrX_+_64804259 0.548 MSN
moesin
chr17_-_53764867 0.546


chr16_+_66236512 0.544 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr16_+_30569675 0.544 PRR14
proline rich 14
chr7_-_144164051 0.543 NM_001042482
NM_022445
TPK1

thiamin pyrophosphokinase 1

chr4_+_39874921 0.540 NM_004310
RHOH
ras homolog gene family, member H
chr8_-_78074851 0.539 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr12_-_78608154 0.538 PAWR
PRKC, apoptosis, WT1, regulator
chr13_+_41744255 0.537 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr1_+_112740380 0.536 LOC100129406
CTTNBP2NL
hypothetical protein LOC100129406
CTTNBP2 N-terminal like
chr1_+_112740322 0.536 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr14_+_92721048 0.535 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr1_+_204797516 0.531 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr20_-_1321571 0.531 FKBP1A
FK506 binding protein 1A, 12kDa
chr9_-_129656778 0.530 ENG
endoglin
chr1_+_22224571 0.529 HSPC157
hypothetical LOC29092
chr2_-_225519974 0.528 DOCK10
dedicator of cytokinesis 10
chr1_+_150428404 0.528


chr3_+_44665220 0.523 NM_003420
ZNF35
zinc finger protein 35
chr2_-_96174502 0.522 DUSP2
dual specificity phosphatase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 4.78e-18 GO:0044260 cellular macromolecule metabolic process
1.28 1.42e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 4.93e-13 GO:0043170 macromolecule metabolic process
1.31 5.39e-13 GO:0090304 nucleic acid metabolic process
1.14 2.29e-10 GO:0044237 cellular metabolic process
1.21 3.70e-09 GO:0034641 cellular nitrogen compound metabolic process
1.20 5.93e-09 GO:0006807 nitrogen compound metabolic process
1.13 6.06e-09 GO:0044238 primary metabolic process
1.29 4.63e-08 GO:0016070 RNA metabolic process
1.27 1.44e-07 GO:0010467 gene expression
1.28 2.85e-07 GO:0009059 macromolecule biosynthetic process
1.28 5.75e-07 GO:0034645 cellular macromolecule biosynthetic process
1.10 1.42e-06 GO:0008152 metabolic process
1.06 3.99e-06 GO:0009987 cellular process
1.26 4.14e-06 GO:0006996 organelle organization
1.17 1.07e-05 GO:0071840 cellular component organization or biogenesis
1.10 1.44e-05 GO:0050789 regulation of biological process
1.19 3.24e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.47 3.34e-05 GO:0001775 cell activation
1.10 3.68e-05 GO:0050794 regulation of cellular process
1.18 4.68e-05 GO:0048518 positive regulation of biological process
1.16 6.23e-05 GO:0016043 cellular component organization
1.16 8.83e-05 GO:0060255 regulation of macromolecule metabolic process
1.40 9.20e-05 GO:0006396 RNA processing
1.09 9.67e-05 GO:0065007 biological regulation
1.19 1.33e-04 GO:0044267 cellular protein metabolic process
1.19 1.74e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 1.77e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.30 2.20e-04 GO:0007049 cell cycle
1.18 2.26e-04 GO:0071842 cellular component organization at cellular level
1.18 3.04e-04 GO:0048522 positive regulation of cellular process
1.34 3.70e-04 GO:0022402 cell cycle process
1.18 4.56e-04 GO:0044249 cellular biosynthetic process
1.39 4.99e-04 GO:0006259 DNA metabolic process
1.62 7.13e-04 GO:0030168 platelet activation
1.17 8.44e-04 GO:0010468 regulation of gene expression
1.17 8.80e-04 GO:0009889 regulation of biosynthetic process
1.41 1.13e-03 GO:0006974 response to DNA damage stimulus
1.17 1.24e-03 GO:0009058 biosynthetic process
1.17 1.32e-03 GO:0031326 regulation of cellular biosynthetic process
1.47 1.38e-03 GO:0006397 mRNA processing
1.14 2.40e-03 GO:0031323 regulation of cellular metabolic process
1.65 2.58e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.65 2.58e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.31 2.91e-03 GO:0046907 intracellular transport
1.37 3.36e-03 GO:0000278 mitotic cell cycle
1.33 3.96e-03 GO:0022403 cell cycle phase
1.62 4.29e-03 GO:0000375 RNA splicing, via transesterification reactions
1.12 4.40e-03 GO:0019222 regulation of metabolic process
1.28 4.76e-03 GO:0032774 RNA biosynthetic process
1.17 9.48e-03 GO:0051252 regulation of RNA metabolic process
1.37 1.04e-02 GO:0016071 mRNA metabolic process
1.13 1.13e-02 GO:0080090 regulation of primary metabolic process
1.15 1.51e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 1.84e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.27 2.39e-02 GO:0009891 positive regulation of biosynthetic process
1.28 2.61e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.16 3.37e-02 GO:0006355 regulation of transcription, DNA-dependent
1.17 3.78e-02 GO:0043412 macromolecule modification
2.14 3.93e-02 GO:0051053 negative regulation of DNA metabolic process
1.53 4.09e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.27 4.17e-02 GO:0033554 cellular response to stress
1.22 4.84e-02 GO:0009893 positive regulation of metabolic process
1.21 4.99e-02 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 2.63e-24 GO:0044424 intracellular part
1.10 2.41e-23 GO:0005622 intracellular
1.12 7.86e-22 GO:0043229 intracellular organelle
1.12 1.15e-21 GO:0043226 organelle
1.14 3.15e-21 GO:0043227 membrane-bounded organelle
1.14 4.03e-21 GO:0043231 intracellular membrane-bounded organelle
1.19 4.30e-19 GO:0005634 nucleus
1.32 6.83e-16 GO:0044428 nuclear part
1.34 1.45e-14 GO:0031981 nuclear lumen
1.30 1.69e-14 GO:0043233 organelle lumen
1.29 2.69e-14 GO:0031974 membrane-enclosed lumen
1.16 3.04e-13 GO:0044446 intracellular organelle part
1.28 1.09e-12 GO:0070013 intracellular organelle lumen
1.16 1.90e-12 GO:0044422 organelle part
1.28 1.63e-11 GO:0005829 cytosol
1.36 3.30e-11 GO:0005654 nucleoplasm
1.10 5.60e-10 GO:0005737 cytoplasm
1.13 6.58e-10 GO:0044444 cytoplasmic part
1.19 2.88e-09 GO:0032991 macromolecular complex
1.51 5.86e-08 GO:0030529 ribonucleoprotein complex
1.19 8.78e-07 GO:0043228 non-membrane-bounded organelle
1.19 8.78e-07 GO:0043232 intracellular non-membrane-bounded organelle
2.12 3.95e-04 GO:0030117 membrane coat
2.12 3.95e-04 GO:0048475 coated membrane
1.32 4.19e-04 GO:0044451 nucleoplasm part
1.15 4.57e-04 GO:0043234 protein complex
1.76 6.56e-04 GO:0005681 spliceosomal complex
1.03 1.28e-03 GO:0044464 cell part
1.03 1.37e-03 GO:0005623 cell
1.37 1.81e-03 GO:0005730 nucleolus
1.34 2.46e-03 GO:0005694 chromosome
1.47 2.89e-03 GO:0015629 actin cytoskeleton
1.34 2.00e-02 GO:0044427 chromosomal part
1.47 3.70e-02 GO:0016604 nuclear body
2.31 3.99e-02 GO:0030119 AP-type membrane coat adaptor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 8.95e-17 GO:0005515 protein binding
1.07 8.70e-12 GO:0005488 binding
1.20 2.19e-09 GO:0003676 nucleic acid binding
1.38 3.44e-07 GO:0003723 RNA binding
1.46 4.79e-04 GO:0003712 transcription cofactor activity
1.45 5.73e-04 GO:0000988 protein binding transcription factor activity
1.45 5.73e-04 GO:0000989 transcription factor binding transcription factor activity
1.16 2.68e-03 GO:0003677 DNA binding
1.55 3.29e-03 GO:0003713 transcription coactivator activity
1.15 9.81e-03 GO:0000166 nucleotide binding
1.28 1.02e-02 GO:0019899 enzyme binding
1.35 1.31e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.35 1.59e-02 GO:0030695 GTPase regulator activity