Motif ID: ELF1,2,4.p2

Z-value: 2.226


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_404543600.757.8e-04Click!
ELF2chr4_-_140317686-0.552.7e-02Click!
ELF4chrX_-_1290721030.116.7e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_110653407 2.656 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr5_+_61910318 2.133 NM_181506
 LRRC70
leucine rich repeat containing 70
chr3_-_184756101 2.093 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr5_-_124108672 2.087 NM_020747
 ZNF608
zinc finger protein 608
chr17_-_18890963 2.001 NM_006613
 GRAP
GRB2-related adaptor protein
chr7_+_150044530 1.947 NM_130759
 GIMAP1
GTPase, IMAP family member 1
chr22_+_25398690 1.808 LOC388889
hypothetical LOC388889
chr15_-_90999606 1.667 NM_207446
 FAM174B
family with sequence similarity 174, member B
chr3_+_120495906 1.658 NM_020754
 ARHGAP31
Rho GTPase activating protein 31
chr8_-_29262240 1.648 NM_057158
 DUSP4
dual specificity phosphatase 4
chr1_-_159306037 1.607 ARHGAP30
Rho GTPase activating protein 30
chr17_-_59451662 1.567 NM_001099786
NM_001099787
NM_001099788
NM_001099789
 ICAM2



intercellular adhesion molecule 2



chr9_+_115303527 1.545 NM_130795
 RGS3
regulator of G-protein signaling 3
chr19_+_3129735 1.513 NM_003775
 S1PR4
sphingosine-1-phosphate receptor 4
chr16_+_66129481 1.463 FAM65A
family with sequence similarity 65, member A
chr14_+_62740878 1.438 NM_020663
 RHOJ
ras homolog gene family, member J
chr14_+_60858151 1.400 NM_006255
 PRKCH
protein kinase C, eta
chr21_+_25856311 1.397 MIR155HG
MIR155 host gene (non-protein coding)
chr3_+_195889845 1.386 FAM43A
family with sequence similarity 43, member A
chr11_+_128069165 1.344 FLI1
Friend leukemia virus integration 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 64 entries
enrichment   p-value GO term description
2.14 3.93e-02 GO:0051053 negative regulation of DNA metabolic process
1.65 2.58e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.65 2.58e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.62 7.13e-04 GO:0030168 platelet activation
1.62 4.29e-03 GO:0000375 RNA splicing, via transesterification reactions
1.53 4.09e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.47 3.34e-05 GO:0001775 cell activation
1.47 1.38e-03 GO:0006397 mRNA processing
1.41 1.13e-03 GO:0006974 response to DNA damage stimulus
1.40 9.20e-05 GO:0006396 RNA processing
1.39 4.99e-04 GO:0006259 DNA metabolic process
1.37 3.36e-03 GO:0000278 mitotic cell cycle
1.37 1.04e-02 GO:0016071 mRNA metabolic process
1.34 3.70e-04 GO:0022402 cell cycle process
1.33 3.96e-03 GO:0022403 cell cycle phase
1.31 5.39e-13 GO:0090304 nucleic acid metabolic process
1.31 2.91e-03 GO:0046907 intracellular transport
1.30 2.20e-04 GO:0007049 cell cycle
1.29 4.63e-08 GO:0016070 RNA metabolic process
1.28 1.42e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
2.31 3.99e-02 GO:0030119 AP-type membrane coat adaptor complex
2.12 3.95e-04 GO:0030117 membrane coat
2.12 3.95e-04 GO:0048475 coated membrane
1.76 6.56e-04 GO:0005681 spliceosomal complex
1.51 5.86e-08 GO:0030529 ribonucleoprotein complex
1.47 2.89e-03 GO:0015629 actin cytoskeleton
1.47 3.70e-02 GO:0016604 nuclear body
1.37 1.81e-03 GO:0005730 nucleolus
1.36 3.30e-11 GO:0005654 nucleoplasm
1.34 1.45e-14 GO:0031981 nuclear lumen
1.34 2.46e-03 GO:0005694 chromosome
1.34 2.00e-02 GO:0044427 chromosomal part
1.32 6.83e-16 GO:0044428 nuclear part
1.32 4.19e-04 GO:0044451 nucleoplasm part
1.30 1.69e-14 GO:0043233 organelle lumen
1.29 2.69e-14 GO:0031974 membrane-enclosed lumen
1.28 1.09e-12 GO:0070013 intracellular organelle lumen
1.28 1.63e-11 GO:0005829 cytosol
1.19 4.30e-19 GO:0005634 nucleus
1.19 2.88e-09 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.55 3.29e-03 GO:0003713 transcription coactivator activity
1.46 4.79e-04 GO:0003712 transcription cofactor activity
1.45 5.73e-04 GO:0000988 protein binding transcription factor activity
1.45 5.73e-04 GO:0000989 transcription factor binding transcription factor activity
1.38 3.44e-07 GO:0003723 RNA binding
1.35 1.31e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.35 1.59e-02 GO:0030695 GTPase regulator activity
1.28 1.02e-02 GO:0019899 enzyme binding
1.20 2.19e-09 GO:0003676 nucleic acid binding
1.16 2.68e-03 GO:0003677 DNA binding
1.15 8.95e-17 GO:0005515 protein binding
1.15 9.81e-03 GO:0000166 nucleotide binding
1.07 8.70e-12 GO:0005488 binding