Motif ID: NFE2.p2

Z-value: 1.200


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2chr12_-_529809840.467.1e-02Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_156923111 2.919 NM_003126
 SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chrX_-_100527799 2.725 NM_000061
 BTK
Bruton agammaglobulinemia tyrosine kinase
chr5_-_141041982 2.628 NM_022481
 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_+_118463906 2.433 NM_001024382
 HMBS
hydroxymethylbilane synthase
chr22_+_21495273 2.418


chr3_-_197549640 2.404 NM_138461
 TM4SF19
transmembrane 4 L six family member 19
chr10_-_6059460 2.306 NM_002189
NM_172200
 IL15RA

interleukin 15 receptor, alpha

chr3_-_197549588 2.296 TM4SF19
transmembrane 4 L six family member 19
chrX_-_154216929 2.233 NM_001289
 CLIC2
chloride intracellular channel 2
chr5_-_141041933 2.190 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr7_-_86526880 2.153 NM_001142749
 KIAA1324L
KIAA1324-like
chr12_-_15005761 2.126 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_12046020 2.035 NM_001243
 TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chrX_+_65299352 1.918 HEPH
hephaestin
chr11_+_384199 1.881 NM_007183
 PKP3
plakophilin 3
chr6_+_106653429 1.814 NM_182907
 PRDM1
PR domain containing 1, with ZNF domain
chr11_+_20342262 1.786 NM_001098523
 HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr4_+_22608252 1.772


chr22_+_21370394 1.747 IGL@
immunoglobulin lambda locus
chr12_-_51629874 1.746 KRT8
keratin 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
4.51 9.02e-03 GO:0006521 regulation of cellular amino acid metabolic process
4.02 1.64e-02 GO:0033238 regulation of cellular amine metabolic process
2.19 3.93e-02 GO:0031401 positive regulation of protein modification process
1.76 2.97e-04 GO:0043067 regulation of programmed cell death
1.75 3.94e-04 GO:0042981 regulation of apoptosis
1.73 6.02e-04 GO:0010941 regulation of cell death
1.60 2.90e-02 GO:0051246 regulation of protein metabolic process
1.31 2.31e-02 GO:0007165 signal transduction
1.29 2.35e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
4.38 3.63e-04 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.68 1.52e-03 GO:0005126 cytokine receptor binding